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Article
Integration of untargeted metabolomics with transcriptomics reveals active metabolic pathways
Cho, K., Evans, B. S., Wood, B. M. K., Kumar, R., Erb, T. J., Warlick, B. P., Gerlt, J. A. & Sweedler, J. V., Jun 1 2015, In: Metabolomics. 11, 3, p. 503-517 15 p.Research output: Contribution to journal › Article › peer-review
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Label-free quantitation of peptide release from neurons in a microfluidic device with mass spectrometry imaging
Zhong, M., Lee, C. Y., Croushore, C. A. & Sweedler, J. V., May 8 2012, In: Lab on a chip. 12, 11, p. 2037-2045 9 p.Research output: Contribution to journal › Article › peer-review
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Lipid Analysis of 30 000 Individual Rodent Cerebellar Cells Using High-Resolution Mass Spectrometry
Neumann, E. K., Ellis, J. F., Triplett, A. E., Rubakhin, S. S. & Sweedler, J. V., Jan 1 2019, In: Analytical Chemistry.Research output: Contribution to journal › Article › peer-review
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Lipid Heterogeneity between Astrocytes and Neurons Revealed by Single-Cell MALDI-MS Combined with Immunocytochemical Classification
Neumann, E. K., Comi, T. J., Rubakhin, S. S. & Sweedler, J. V., Apr 23 2019, In: Angewandte Chemie - International Edition. 58, 18, p. 5910-5914 5 p.Research output: Contribution to journal › Article › peer-review
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MALDI-guided SIMS: Multiscale imaging of metabolites in bacterial biofilms
Lanni, E. J., Masyuko, R. N., Driscoll, C. M., Aerts, J. T., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Sep 1 2014, In: Analytical chemistry. 86, 18, p. 9139-9145 7 p.Research output: Contribution to journal › Article › peer-review
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MALDI mass spectrometry imaging of neuronal cell cultures
Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 2011, In: Journal of the American Society for Mass Spectrometry. 22, 5, p. 828-836 9 p.Research output: Contribution to journal › Article › peer-review
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MALDI MS Guided Liquid Microjunction Extraction for Capillary Electrophoresis-Electrospray Ionization MS Analysis of Single Pancreatic Islet Cells
Comi, T. J., Makurath, M. A., Philip, M. C., Rubakhin, S. S. & Sweedler, J. V., Jul 18 2017, In: Analytical Chemistry. 89, 14, p. 7765-7772 8 p.Research output: Contribution to journal › Article › peer-review
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Mass spectrometry imaging and GC-MS profiling of the mammalian peripheral sensory-motor circuit
Rubakhin, S. S., Ulanov, A. & Sweedler, J. V., Jun 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 6, p. 958-966 9 p.Research output: Contribution to journal › Article › peer-review
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Mass spectrometry imaging and identification of peptides associated with cephalic ganglia regeneration in Schmidtea mediterranea
Ong, T. H., Romanova, E. V., Roberts-Galbraith, R. H., Yang, N., Zimmerman, T. A., Collins, J. J., Lee, J. E., Kelleher, N. L., Newmark, P. A. & Sweedler, J. V., Apr 8 2016, In: Journal of Biological Chemistry. 291, 15, p. 8109-8120 12 p.Research output: Contribution to journal › Article › peer-review
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Mass spectrometry imaging of complex microbial communities
Dunham, S. J. B., Ellis, J. F., Li, B. & Sweedler, J. V., 2017, In: Accounts of chemical research. 50, 1, p. 96-104 9 p.Research output: Contribution to journal › Article › peer-review
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Mechanical tension modulates local and global vesicle dynamics in neurons
Ahmed, W. W., Li, T. C., Rubakhin, S. S., Chiba, A., Sweedler, J. V. & Saif, T. A., Jun 1 2012, In: Cellular and Molecular Bioengineering. 5, 2, p. 155-164 10 p.Research output: Contribution to journal › Article › peer-review
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Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry
Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Sep 1 2011, In: Analytical chemistry. 83, 17, p. 6810-6817 8 p.Research output: Contribution to journal › Article › peer-review
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Metal-assisted polyatomic SIMS and laser desorption/ionization for enhanced small molecule imaging of bacterial biofilms
Dunham, S. J. B., Comi, T. J., Ko, K., Li, B., Baig, N. F., Morales-Soto, N., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Jun 1 2016, In: Biointerphases. 11, 2, 02A325.Research output: Contribution to journal › Article › peer-review
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Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord
Miller, L. K., Hou, X., Rodriguiz, R. M., Gagnidze, K., Sweedler, J. V., Wetsel, W. C. & Devi, L. A., Dec 2011, In: Journal of Neurochemistry. 119, 5, p. 1074-1085 12 p.Research output: Contribution to journal › Article › peer-review
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Microbeam-coupled capillary electrophoresis
Garty, G., Ehsan, M. U., Buonanno, M., Yang, Z., Sweedler, J. V. & Brenner, D. J., Sep 1 2015, In: Radiation Protection Dosimetry. 166, 1-4, p. 188-191 4 p., ncv148.Research output: Contribution to journal › Article › peer-review
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Microfluidic device for the selective chemical stimulation of neurons and characterization of peptide release with mass spectrometry
Croushore, C. A., Supharoek, S. A., Lee, C. Y., Jakmunee, J. & Sweedler, J. V., Nov 6 2012, In: Analytical Chemistry. 84, 21, p. 9446-9452 7 p.Research output: Contribution to journal › Article › peer-review
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microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling
Comi, T. J., Neumann, E. K., Do, T. D. & Sweedler, J. V., Sep 1 2017, In: Journal of the American Society for Mass Spectrometry. 28, 9, p. 1919-1928 10 p.Research output: Contribution to journal › Article › peer-review
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Molecular organization of drosophila neuroendocrine cells by dimmed
Park, D., Hadžić, T., Yin, P., Rusch, J., Abruzzi, K., Rosbash, M., Skeath, J. B., Panda, S., Sweedler, J. V. & Taghert, P. H., Sep 27 2011, In: Current Biology. 21, 18, p. 1515-1524 10 p.Research output: Contribution to journal › Article › peer-review
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Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
Park, H. M., Satta, R., Davis, R. G., Goo, Y. A., Leduc, R. D., Fellers, R. T., Greer, J. B., Romanova, E. V., Rubakhin, S. S., Tai, R., Thomas, P. M., Sweedler, J. V., Kelleher, N. L., Patrie, S. M. & Lasek, A. W., Nov 1 2019, In: Journal of Proteome Research. 18, 11, p. 3999-4012 14 p.Research output: Contribution to journal › Article › peer-review
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Multimodal chemical imaging of molecular messengers in emerging Pseudomonas aeruginosa bacterial communities
Baig, N. F., Dunham, S. J. B., Morales-Soto, N., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 7 2015, In: Analyst. 140, 19, p. 6544-6552 9 p.Research output: Contribution to journal › Article › peer-review
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Nanopipet-based liquid-liquid interface probes for the electrochemical detection of acetylcholine, tryptamine, and serotonin via ionic transfer
Colombo, M. L., Sweedler, J. V. & Shen, M., May 19 2015, In: Analytical chemistry. 87, 10, p. 5095-5100 6 p.Research output: Contribution to journal › Article › peer-review
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On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues
Wu, Q., Comi, T. J., Li, B., Rubakhin, S. S. & Sweedler, J. V., Jun 7 2016, In: Analytical Chemistry. 88, 11, p. 5988-5995 8 p.Research output: Contribution to journal › Article › peer-review
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Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens
Zhang, P., Moye, L. S., Southey, B. R., Dripps, I., Sweedler, J. V., Pradhan, A. & Rodriguez-Zas, S. L., Dec 1 2019, In: Molecular Neurobiology. 56, 12, p. 7929-7949 21 p.Research output: Contribution to journal › Article › peer-review
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PACAP and other neuropeptide targets link chronic migraine and opioid-induced hyperalgesia in mouse models
Anapindi, K. D. B., Yang, N., Romanova, E. V., Rubakhin, S. S., Tipton, A., Dripps, I., Sheets, Z., Sweedler, J. V. & Pradhan, A. A., 2019, In: Molecular and Cellular Proteomics. 18, 12, p. 2447-2458 12 p.Research output: Contribution to journal › Article › peer-review
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Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization
Aerts, J. T., Louis, K. R., Crandall, S. R., Govindaiah, G., Cox, C. L. & Sweedler, J. V., 2014, In: Analytical chemistry. 86, 6, p. 3203-3208 6 p.Research output: Contribution to journal › Article › peer-review
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Peptidomic analyses of mouse astrocytic cell lines and rat primary cultured astrocytes
Yin, P., Knolhoff, A. M., Rosenberg, H. J., Millet, L. J., Gillette, M. U. & Sweedler, J. V., Aug 3 2012, In: Journal of Proteome Research. 11, 8, p. 3965-3973 9 p.Research output: Contribution to journal › Article › peer-review
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Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System
Tillmaand, E. G., Yang, N., Kindt, C. A. C., Romanova, E. V., Rubakhin, S. S. & Sweedler, J. V., Dec 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 12, p. 2051-2061 11 p.Research output: Contribution to journal › Article › peer-review
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Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine
Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In: mBio. 5, 1, e00933-13.Research output: Contribution to journal › Article › peer-review
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Probing the production of amidated peptides following genetic and dietary copper manipulations
Yin, P., Bousquet-Moore, D., Annangudi, S. P., Southey, B. R., Mains, R. E., Eipper, B. A. & Sweedler, J. V., Dec 16 2011, In: PloS one. 6, 12, e28679.Research output: Contribution to journal › Article › peer-review
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Profiling metabolites and peptides in single cells
Rubakhin, S. S., Romanova, E. V., Nemes, P. & Sweedler, J. V., Apr 2011, In: Nature Methods. 8, 4, p. S20-S29Research output: Contribution to journal › Article › peer-review
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Profiling of Microbial Colonies for High-Throughput Engineering of Multistep Enzymatic Reactions via Optically Guided Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
Si, T., Li, B., Comi, T. J., Wu, Y., Hu, P., Wu, Y., Min, Y., Mitchell, D. A., Zhao, H. & Sweedler, J. V., 2017, In: Journal of the American Chemical Society. 139, 36, p. 12466-12473 8 p.Research output: Contribution to journal › Article › peer-review
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Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models
Tillmaand, E. G., Anapindi, K. D. B., De La Toba, E. A., Guo, C. J., Krebs, J., Lenhart, A. E., Liu, Q. & Sweedler, J. V., Mar 6 2020, In: Journal of Proteome Research. 19, 3, p. 1248-1257 10 p.Research output: Contribution to journal › Article › peer-review
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Quantitative Imprint Mass Spectrometry Imaging of Endogenous Ceramides in Rat Brain Tissue with Kinetic Calibration
Wu, Q., Rubakhin, S. S. & Sweedler, J. V., May 5 2020, In: Analytical chemistry. 92, 9, p. 6613-6621 9 p.Research output: Contribution to journal › Article › peer-review
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Quantitative Reflection Imaging for the Morphology and Dynamics of Live Aplysia californica Pedal Ganglion Neurons Cultured on Nanostructured Plasmonic Crystals
Kang, S., Badea, A., Rubakhin, S. S., Sweedler, J. V., Rogers, J. A. & Nuzzo, R. G., Sep 5 2017, In: Langmuir. 33, 35, p. 8640-8650 11 p.Research output: Contribution to journal › Article › peer-review
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Rapid mitogenic regulation of the mTORC1 Inhibitor, DEPTOR, by phosphatidic acid
Yoon, M. S., Rosenberger, C. L., Wu, C., Truong, N., Sweedler, J. V. & Chen, J., May 7 2015, In: Molecular cell. 58, 3, p. 549-556 8 p.Research output: Contribution to journal › Article › peer-review
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Relative quantitation of neuropeptides over a thousand-fold concentration range
Hou, X., Xie, F. & Sweedler, J. V., Dec 2012, In: Journal of the American Society for Mass Spectrometry. 23, 12, p. 2083-2093 11 p.Research output: Contribution to journal › Article › peer-review
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Removing Formaldehyde-Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin-Fixed Paraffin-Embedded Tissues
Lee, D. K., Rubakhin, S. S., Kusmartseva, I., Wasserfall, C., Atkinson, M. A. & Sweedler, J. V., Dec 7 2020, In: Angewandte Chemie - International Edition. 59, 50, p. 22584-22590 7 p.Research output: Contribution to journal › Article › peer-review
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Seasonal adaptations of the hypothalamo-neurohypophyseal system of the dromedary camel
Alim, F. Z. D., Romanova, E. V., Tay, Y. L., Rahman, A. Y. B. A., Chan, K. G., Hong, K. W., Rogers, M., Southey, B. R., Greenwood, M. P., Mecawi, A. S., Mustafa, M. R., Mahy, N., Campbell, C., Antunes-Rodrigues, J., Sweedler, J. V., Murphy, D. & Hindmarch, C. C. T., Jun 2019, In: PloS one. 14, 6, e0216679.Research output: Contribution to journal › Article › peer-review
Open Access -
Secondary ion mass spectrometry imaging of molecular distributions in cultured neurons and their processes: Comparative analysis of sample preparation
Tucker, K. R., Li, Z., Rubakhin, S. S. & Sweedler, J. V., Nov 2012, In: Journal of the American Society for Mass Spectrometry. 23, 11, p. 1931-1938 8 p.Research output: Contribution to journal › Article › peer-review
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Serotonin of mast cell origin contributes to hippocampal function
Nautiyal, K. M., Dailey, C. A., Jahn, J. L., Rodriquez, E., Son, N. H., Sweedler, J. V. & Silver, R., Aug 2012, In: European Journal of Neuroscience. 36, 3, p. 2347-2359 13 p.Research output: Contribution to journal › Article › peer-review
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Single-Cell Classification Using Mass Spectrometry through Interpretable Machine Learning
Xie, Y. R., Castro, D. C., Bell, S. E., Rubakhin, S. & Sweedler, J. V., Jul 7 2020, In: Analytical chemistry. 92, 13, p. 9338-9347 10 p.Research output: Contribution to journal › Article › peer-review
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Single-cell metabolomics: Changes in the metabolome of freshly isolated and cultured neurons
Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Oct 17 2012, In: ACS Chemical Neuroscience. 3, 10, p. 782-792 11 p.Research output: Contribution to journal › Article › peer-review
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Single Cell Peptide Heterogeneity of Rat Islets of Langerhans
Jansson, E. T., Comi, T. J., Rubakhin, S. S. & Sweedler, J. V., Sep 16 2016, In: ACS chemical biology. 11, 9, p. 2588-2595 8 p.Research output: Contribution to journal › Article › peer-review
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Single Cell Profiling Using Ionic Liquid Matrix-Enhanced Secondary Ion Mass Spectrometry for Neuronal Cell Type Differentiation
Do, T. D., Comi, T. J., Dunham, S. J. B., Rubakhin, S. S. & Sweedler, J. V., Mar 7 2017, In: Analytical Chemistry. 89, 5, p. 3078-3086 9 p.Research output: Contribution to journal › Article › peer-review
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Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry
Amaya, K. R., Sweedler, J. V. & Clayton, D. F., Aug 2011, In: Journal of Neurochemistry. 118, 4, p. 499-511 13 p.Research output: Contribution to journal › Article › peer-review
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Spatial organization of pseudomonas aeruginosa biofilms probed by combined matrix-assisted laser desorption ionization mass spectrometry and confocal raman microscopy
Masyuko, R. N., Lanni, E. J., Driscoll, C. M., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 15 2014, In: Analyst. 139, 22, p. 5700-5708 9 p.Research output: Contribution to journal › Article › peer-review
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Spatiotemporal distribution of Pseudomonas aeruginosa alkyl quinolones under metabolic and competitive stress
Cao, T., Sweedler, J. V., Bohn, P. W. & Shrout, J. D., Jul 1 2020, In: mSphere. 5, 4, e00426-20.Research output: Contribution to journal › Article › peer-review
Open Access -
Stretched tissue mounting for MALDI mass spectrometry imaging
Tucker, K. R., Lanni, E. J., Serebryannyy, L. A., Rubakhin, S. & Sweedler, J. V., Dec 1 2011, In: Analytical chemistry. 83, 23, p. 9181-9185 5 p.Research output: Contribution to journal › Article › peer-review
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Targeted single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons
Neupert, S., Rubakhin, S. S. & Sweedler, J. V., Aug 24 2012, In: Chemistry and Biology. 19, 8, p. 1010-1019 10 p.Research output: Contribution to journal › Article › peer-review
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The ctenophore genome and the evolutionary origins of neural systems
Moroz, L. L., Kocot, K. M., Citarella, M. R., Dosung, S., Norekian, T. P., Povolotskaya, I. S., Grigorenko, A. P., Dailey, C., Berezikov, E., Buckley, K. M., Ptitsyn, A., Reshetov, D., Mukherjee, K., Moroz, T. P., Bobkova, Y., Yu, F., Kapitonov, V. V., Jurka, J., Bobkov, Y. V., Swore, J. J. & 16 others, , 2014, In: Nature. 510, 7503, p. 109-114 6 p.Research output: Contribution to journal › Article › peer-review