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Author

  • John E Cronan
Article

A Biotin Biosynthesis Gene Restricted to Helicobacter

Bi, H., Zhu, L., Jia, J. & Cronan, J. E., Feb 12 2016, In : Scientific reports. 6, 21162.

Research output: Contribution to journalArticle

A complex lipoate utilization pathway in Listeria monocytogenes

Christensen, Q. H., Hagar, J. A., O'Riordan, M. X. D. & Cronan, J. E., Sep 9 2011, In : Journal of Biological Chemistry. 286, 36, p. 31447-31456 10 p.

Research output: Contribution to journalArticle

A Francisella virulence factor catalyses an essential reaction of biotin synthesis

Feng, Y., Napier, B. A., Manandhar, M., Henke, S. K., Weiss, D. S. & Cronan, J. E., Jan 2014, In : Molecular Microbiology. 91, 2, p. 300-314 15 p.

Research output: Contribution to journalArticle

Altered regulation of escherichia coli biotin biosynthesis in bira superrepressor mutant strains

Chakravartty, V. & Cronan, J. E., Mar 2012, In : Journal of bacteriology. 194, 5, p. 1113-1126 14 p.

Research output: Contribution to journalArticle

An Atypical α/β-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae

Shi, J., Cao, X., Chen, Y., Cronan, J. E. & Guo, Z., Dec 6 2016, In : Biochemistry. 55, 48, p. 6705-6717 13 p.

Research output: Contribution to journalArticle

A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis

Christensen, Q. H., Martin, N., Mansilla, M. C., de Mendoza, D. & Cronan, J. E., Apr 2011, In : Molecular Microbiology. 80, 2, p. 350-363 14 p.

Research output: Contribution to journalArticle

A novel synthesis of trans-unsaturated fatty acids by the Gram-positive commensal bacterium Enterococcus faecalis FA2-2

Kondakova, T., Kumar, S. & Cronan, J. E., Aug 2019, In : Chemistry and Physics of Lipids. 222, p. 23-35 13 p.

Research output: Contribution to journalArticle

A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis

Martin, N., Christensen, Q. H., Mansilla, M. C., Cronan, J. E. & de Mendoza, D., Apr 2011, In : Molecular Microbiology. 80, 2, p. 335-349 15 p.

Research output: Contribution to journalArticle

Antibacterial activity of N-pentylpantothenamide is due to inhibition of coenzyme A synthesis

Thomas, J. & Cronan, J. E., Mar 2010, In : Antimicrobial Agents and Chemotherapy. 54, 3, p. 1374-1377 4 p.

Research output: Contribution to journalArticle

A series of medium and high copy number arabinose-inducible Escherichia coli expression vectors compatible with pBR322 and pACYC184

Chakravartty, V. & Cronan, J. E., Sep 1 2015, In : Plasmid. 81, p. 21-26 6 p.

Research output: Contribution to journalArticle

Biosynthesis of squalene from farnesyl diphosphate in Bacteria: Three steps catalyzed by three enzymes

Pan, J. J., Solbiati, J. O., Ramamoorthy, G., Hillerich, B. S., Seidel, R. D., Cronan, J. E., Almo, S. C. & Poulter, C. D., May 27 2015, In : ACS Central Science. 1, 2, p. 77-82 6 p.

Research output: Contribution to journalArticle

Biotin and lipoic acid: Synthesis, attachment, and regulation

Cronan, J. E., Jan 1 2014, In : EcoSal Plus. 6, 1, p. 1-39 39 p.

Research output: Contribution to journalArticle

Biotin synthesis begins by hijacking the fatty acid synthetic pathway

Lin, S., Hanson, R. E. & Cronan, J. E., Sep 2010, In : Nature chemical biology. 6, 9, p. 682-688 7 p.

Research output: Contribution to journalArticle

Complex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters

Feng, Y. & Cronan, J. E., Apr 2011, In : Molecular Microbiology. 80, 1, p. 195-218 24 p.

Research output: Contribution to journalArticle

Crosstalk of Escherichia coli FadR with Global Regulators in Expression of Fatty Acid Transport Genes

Feng, Y. & Cronan, J. E., Sep 28 2012, In : PloS one. 7, 9, e46275.

Research output: Contribution to journalArticle

Dimerization of the bacterial biotin carboxylase subunit is required for acetyl coenzyme A carboxylase activity In vivo

Smith, A. C. & Cronan, J. E., Jan 2012, In : Journal of bacteriology. 194, 1, p. 72-78 7 p.

Research output: Contribution to journalArticle

Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation

Goble, A. M., Feng, Y., Raushel, F. M. & Cronan, J. E., Dec 20 2013, In : ACS chemical biology. 8, 12, p. 2622-2629 8 p.

Research output: Contribution to journalArticle

Discovery of new enzymes and metabolic pathways by using structure and genome context

Zhao, S., Kumar, R., Sakai, A., Vetting, M. W., Wood, B. M. K., Brown, S., Bonanno, J. B., Hillerich, B. S., Seidel, R. D., Babbitt, P. C., Almo, S. C., Sweedler, J. V., Gerlt, J. A., Cronan, J. E. & Jacobson, M. P., 2013, In : Nature. 502, 7473, p. 698-702 5 p.

Research output: Contribution to journalArticle

Enterococcus faecalis encodes an atypical auxiliary acyl carrier protein required for efficient regulation of fatty acid synthesis by exogenous fatty acids

Zhu, L., Zou, Q., Cao, X. & Cronan, J. E., May 1 2019, In : mBio. 10, 3, e00577-19.

Research output: Contribution to journalArticle

Open Access

Escherichia coli vectors having stringently repressible replication origins allow a streamlining of Crispr/Cas9 gene editing

Srinivas, S., Hu, Z. & Cronan, J. E., May 2019, In : Plasmid. 103, p. 53-62 10 p.

Research output: Contribution to journalArticle

Evidence against translational repression by the carboxyltransferase component of Escherichia coli acetyl coenzyme a carboxylase

Smith, A. C. & Cronan, J. E., Jan 1 2014, In : Journal of bacteriology. 196, 21, p. 3768-3775 8 p.

Research output: Contribution to journalArticle

Evolution of a new function in an esterase: Simple amino acid substitutions enable the activity present in the larger paralog, BioH

Flores, H., Lin, S., Contreras-Ferrat, G., Cronan, J. E. & Morett, E., Aug 2012, In : Protein Engineering, Design and Selection. 25, 8, p. 387-395 9 p.

Research output: Contribution to journalArticle

Experimental strategies for functional annotation and metabolism discovery: Targeted screening of solute binding proteins and unbiased panning of metabolomes

Vetting, M. W., Al-Obaidi, N., Zhao, S., San Francisco, B., Kim, J., Wichelecki, D. J., Bouvier, J. T., Solbiati, J. O., Vu, H., Zhang, X., Rodionov, D. A., Love, J. D., Hillerich, B. S., Seidel, R. D., Quinn, R. J., Osterman, A. L., Cronan, J. E., Jacobson, M. P., Gerlt, J. A. & Almo, S. C., Jan 27 2015, In : Biochemistry. 54, 3, p. 909-931 23 p.

Research output: Contribution to journalArticle

Expression and activity of the BioH esterase of biotin synthesis is independent of genome context

Cao, X., Zhu, L., Hu, Z. & Cronan, J. E., Dec 1 2017, In : Scientific reports. 7, 1, 2141.

Research output: Contribution to journalArticle

Expression of Vibrio harveyi Acyl-ACP synthetase allows efficient entry of exogenous fatty acids into the Escherichia coli fatty acid and lipid a synthetic pathways

Jiang, Y., Morgan-Kiss, R. M., Campbell, J. W., Chan, C. H. & Cronan, J. E., Feb 2 2010, In : Biochemistry. 49, 4, p. 718-726 9 p.

Research output: Contribution to journalArticle

FabQ, a dual-function dehydratase/isomerase, circumvents the last step of the classical fatty acid synthesis cycle

Bi, H., Wang, H. & Cronan, J. E., Sep 19 2013, In : Chemistry and Biology. 20, 9, p. 1157-1167 11 p.

Research output: Contribution to journalArticle

Inefficient translation renders the enterococcus faecalis fabk enoyl- acyl carrier protein reductase phenotypically cryptic

Bi, H., Zhu, L., Wang, H. & Cronan, J. E., Jan 1 2014, In : Journal of bacteriology. 196, 1, p. 170-179 10 p.

Research output: Contribution to journalArticle

Intein-mediated cyclization of bacterial acyl carrier protein stabilizes its folded conformation but does not abolish function

Volkmann, G., Murphy, P. W., Rowland, E. E., Cronan, J. E., Liu, X. Q., Blouin, C. & Byers, D. M., Mar 19 2010, In : Journal of Biological Chemistry. 285, 12, p. 8605-8614 10 p.

Research output: Contribution to journalArticle

Lipoate-binding proteins and specific lipoate-protein ligases in microbial sulfur oxidation reveal an atpyical role for an old cofactor

Cao, X., Koch, T., Steffens, L., Finkensieper, J., Zigann, R., Cronan, J. E. & Dahl, C., Jul 13 2018, In : eLife. 7, e37439.

Research output: Contribution to journalArticle

Lipoic acid synthesis: A new family of octanoyltransferases generally annotated as lipoate protein ligases

Christensen, Q. H. & Cronan, J. E., Nov 23 2010, In : Biochemistry. 49, 46, p. 10024-10036 13 p.

Research output: Contribution to journalArticle

Novel Xanthomonas campestris long-chain-specific 3-oxoacyl- acyl carrier protein reductase involved in diffusible signal factor synthesis

Hu, Z., Dong, H., Ma, J. C., Yu, Y., Li, K. H., Guo, Q. Q., Zhang, C., Zhang, W. B., Cao, X., Cronan, J. E. & Wang, H., May 1 2018, In : mBio. 9, 3, e00596-18.

Research output: Contribution to journalArticle

Only one of the five Ralstonia solanacearum long-chain 3-ketoacyl-acyl carrier protein synthase homologues functions in fatty acid synthesis

Cheng, J., Ma, J., Lin, J., Fan, Z. C., Cronan, J. E. & Wang, H., Mar 2012, In : Applied and environmental microbiology. 78, 5, p. 1563-1573 11 p.

Research output: Contribution to journalArticle

Overlapping repressor binding sites result in additive regulation of Escherichia coli FadH by FadR and ArcA

Feng, Y. & Cronan, J. E., Sep 2010, In : Journal of bacteriology. 192, 17, p. 4289-4299 11 p.

Research output: Contribution to journalArticle

PBR322 vectors having tetracycline-dependent replication

Cronan, J. E., Mar 1 2016, In : Plasmid. 84-85, p. 20-26 7 p.

Research output: Contribution to journalArticle

PdhR, the pyruvate dehydrogenase repressor, does not regulate lipoic acid synthesis

Feng, Y. & Cronan, J. E., Jul 2014, In : Research in Microbiology. 165, 6, p. 429-438 10 p.

Research output: Contribution to journalArticle

Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In : mBio. 5, 1, e00933-13.

Research output: Contribution to journalArticle

Profligate biotin synthesis in α-proteobacteria - a developing or degenerating regulatory system?

Feng, Y., Zhang, H. & Cronan, J. E., Apr 2013, In : Molecular Microbiology. 88, 1, p. 77-92 16 p.

Research output: Contribution to journalArticle

Proofreading of noncognate Acyl adenylates by an acyl-coenzyme a ligase

Manandhar, M. & Cronan, J. E., Dec 19 2013, In : Chemistry and Biology. 20, 12, p. 1441-1446 6 p.

Research output: Contribution to journalArticle

Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism

Hassan, B. H. & Cronan, J. E., Mar 11 2011, In : Journal of Biological Chemistry. 286, 10, p. 8263-8276 14 p.

Research output: Contribution to journalArticle

Remarkable Diversity in the Enzymes Catalyzing the Last Step in Synthesis of the Pimelate Moiety of Biotin

Shapiro, M. M., Chakravartty, V. & Cronan, J. E., Nov 9 2012, In : PloS one. 7, 11, e49440.

Research output: Contribution to journalArticle