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• Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry

  Nemes, P., Rubakhin, S. S., Aerts, J. T. & Sweedler, J. V., Apr 2013, In: Nature Protocols. 8, 4, p. 783-799 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Metabolomics
  • Electrospray Ionization Mass Spectrometry
  • Capillary Electrophoresis

• Publish only your original research

  Sweedler, J. V., Apr 1 2014, In: Analytical chemistry. 86, 7, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Progress toward single cell metabolomics

  Rubakhin, S. S., Lanni, E. J. & Sweedler, J. V., Feb 2013, In: Current Opinion in Biotechnology. 24, 1, p. 95-104 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolomics
  • Metabolites
  • Molecules
  • Mass spectrometry
  • Microfluidics

• Profiling of Microbial Colonies for High-Throughput Engineering of Multistep Enzymatic Reactions via Optically Guided Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

  Si, T., Li, B., Comi, T. J., Wu, Y., Hu, P., Wu, Y., Min, Y., Mitchell, D. A., Zhao, H. & Sweedler, J. V., 2017, In: Journal of the American Chemical Society. 139, 36, p. 12466-12473 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Desorption
  • ionization

• Production of nitric oxide within the aplysia californica nervous system

  Ye, X., Xie, F., Romanova, E. V., Rubakhin, S. S. & Sweedler, J. V., Mar 17 2010, In: ACS Chemical Neuroscience. 1, 3, p. 182-193 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Aplysia
  • Neurology
  • Fluorescence
  • Nervous System
  • Nitric Oxide

• Preface

  Rubakhin, S. & Sweedler, J. V., Dec 1 2010, In: Methods in Molecular Biology. 656

  Research output: Contribution to journal › Article › peer-review

• Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

  Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In: mBio. 5, 1, e00933-13.

  Research output: Contribution to journal › Article › peer-review

  • stachydrine
  • Betaine
  • Paracoccus denitrificans
  • Hydroxyproline
  • Metabolomics

• Pittcon: Still vibrant after more than 60 years

  Sweedler, J. V., Mar 5 2013, In: Analytical chemistry. 85, 5, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Peptidomics for the discovery and characterization of neuropeptides and hormones

  Romanova, E. V. & Sweedler, J. V., Sep 12 2015, In: Trends in Pharmacological Sciences. 36, 9, p. 579-586 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neuropeptides
  • G-Protein-Coupled Receptors
  • Hormones
  • Orphaned Children
  • Mass spectrometry

• Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System

  Tillmaand, E. G., Yang, N., Kindt, C. A. C., Romanova, E. V., Rubakhin, S. S. & Sweedler, J. V., Dec 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 12, p. 2051-2061 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Spinal Ganglia
  • Mass spectrometry
  • Peptides
  • Spinal Nerve Roots
  • Mass Spectrometry

• Peptide identifications and false discovery rates using different mass spectrometry platforms

  Anapindi, K. D. B., Romanova, E. V., Southey, B. R. & Sweedler, J. V., May 15 2018, In: Talanta. 182, p. 456-463 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Peptides
  • Neuropeptides
  • Protein Precursors
  • Bioinformatics

• Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization

  Aerts, J. T., Louis, K. R., Crandall, S. R., Govindaiah, G., Cox, C. L. & Sweedler, J. V., 2014, In: Analytical chemistry. 86, 6, p. 3203-3208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillary electrophoresis
  • Metabolomics
  • Electrophysiology
  • Mass spectrometry
  • Clamping devices

• Our editorial team

  Sweedler, J. V., Jun 2 2015, In: Analytical chemistry. 87, 11, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Optically Guided Single Cell Mass Spectrometry of Rat Dorsal Root Ganglia to Profile Lipids, Peptides and Proteins

  Do, T. D., Ellis, J. F., Neumann, E. K., Comi, T. J., Tillmaand, E. G., Lenhart, A. E., Rubakhin, S. S. & Sweedler, J. V., May 22 2018, In: ChemPhysChem. 19, 10, p. 1180-1191 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Rats
  • peptides
  • rats
  • lipids

• Non-targeted identification of d-amino acid-containing peptides through enzymatic screening, chiral amino acid analysis, and LC-MS

  Tai, H. C., Checco, J. W. & Sweedler, J. V., 2018, Methods in Molecular Biology. Humana Press Inc., p. 107-118 12 p. (Methods in Molecular Biology; vol. 1719).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amino Acids
  • Peptides
  • Post Translational Protein Processing
  • Mass Spectrometry
  • Animals

• New Mass Spectrometric Approaches for Uncovering Neuropeptides

  Hou, X. & Sweedler, J. V., Aug 29 2013, Handbook of Biologically Active Peptides. Elsevier Inc., p. 1749-1756 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Newly Identified Aplysia SPTR-Gene Family-Derived Peptides: Localization and Function

  Zhang, G., Yuan, W. D., Vilim, F. S., Romanova, E. V., Yu, K., Yin, S. Y., Le, Z. W., Xue, Y. Y., Chen, T. T., Chen, G. K., Chen, S. A., Cropper, E. C., Sweedler, J. V., Weiss, K. R. & Jing, J., Aug 15 2018, In: ACS Chemical Neuroscience. 9, 8, p. 2041-2053 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Aplysia
  • Interneurons
  • Genes
  • Cheek
  • Peptides

• Neuropeptidomics of the Rat Habenular Nuclei

  Yang, N., Anapindi, K. D. B., Rubakhin, S. S., Wei, P., Yu, Q., Li, L., Kenny, P. J. & Sweedler, J. V., Apr 6 2018, In: Journal of Proteome Research. 17, 4, p. 1463-1473 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Habenula
  • Mass spectrometry
  • Rats
  • Tandem Mass Spectrometry
  • Neuropeptides

• Neuropeptide release is impaired in a mouse model of fragile x mental retardation syndrome

  Annangudi, S. P., Luszpak, A. E., Kim, S. H., Ren, S., Hatcher, N. G., Weiler, I. J., Thornley, K. T., Kile, B. M., Wightman, R. M., Greenough, W. T. & Sweedler, J. V., Apr 21 2010, In: ACS Chemical Neuroscience. 1, 4, p. 306-314 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Fragile X Mental Retardation Protein
  • Neuropeptides
  • Intellectual Disability
  • Fragile X Syndrome
  • Biogenic Amines

• Nanopipet-based liquid-liquid interface probes for the electrochemical detection of acetylcholine, tryptamine, and serotonin via ionic transfer

  Colombo, M. L., Sweedler, J. V. & Shen, M., May 19 2015, In: Analytical chemistry. 87, 10, p. 5095-5100 6 p.

  Research output: Contribution to journal › Article › peer-review

  • tryptamine
  • Acetylcholine
  • Serotonin
  • Electrodes
  • Liquids

• Nanofluidics in chemical analysis

  Piruska, A., Gong, M., Sweedler, J. V. & Bohn, P. W., Feb 24 2010, In: Chemical Society Reviews. 39, 3, p. 1060-1072 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Nanofluidics
  • Nanopores
  • Chemical analysis
  • Microfluidics
  • Microsensors

• Multimodal chemical imaging of molecular messengers in emerging Pseudomonas aeruginosa bacterial communities

  Baig, N. F., Dunham, S. J. B., Morales-Soto, N., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 7 2015, In: Analyst. 140, 19, p. 6544-6552 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Multimodal Imaging
  • Biofilms
  • Pseudomonas aeruginosa
  • biofilm
  • Oxides

• Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging

  Neumann, E. K., Comi, T. J., Spegazzini, N., Mitchell, J. W., Rubakhin, S. S., Gillette, M. U., Bhargava, R. & Sweedler, J. V., Oct 2 2018, In: Analytical Chemistry. 90, 19, p. 11572-11580 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Infrared radiation
  • Brain
  • Imaging techniques
  • Chemical analysis

• Multifactorial understanding of ion abundance in tandem mass spectrometry experiments

  Fazal, Z., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., 2013, In: Journal of Proteomics and Bioinformatics. 6, 2, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Ions
  • Peptides
  • Experiments

• Molecular and Physiological Characterization of a Receptor for d -Amino Acid-Containing Neuropeptides

  Checco, J. W., Zhang, G., Yuan, W. D., Yu, K., Yin, S. Y., Roberts-Galbraith, R. H., Yau, P. M., Romanova, E. V., Jing, J. & Sweedler, J. V., May 18 2018, In: ACS chemical biology. 13, 5, p. 1343-1352 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Receptors
  • Neuropeptides
  • Neuropeptide Receptors
  • Amino Acids
  • Aplysia

• Microscale transport physics during atomic force microscopy mass spectrometry and improved sampling efficiency

  Moon, H., Comi, T. J., Dunham, S. J. B., Kwon, B., Sweedler, J. V. & King, W. P., Jul 26 2017, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., p. 24-27 4 p. 7993978. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Mass spectrometry
  • Atomic force microscopy
  • microbalances
  • mass spectroscopy
  • Physics

• microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling

  Comi, T. J., Neumann, E. K., Do, T. D. & Sweedler, J. V., Sep 1 2017, In: Journal of the American Society for Mass Spectrometry. 28, 9, p. 1919-1928 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Boidae
  • Mass spectrometry
  • Mass Spectrometry
  • Microscopic examination
  • Microscopy

• Microfluidic systems for studying neurotransmitters and neurotransmission

  Croushore, C. A. & Sweedler, J. V., May 7 2013, In: Lab on a chip. 13, 9, p. 1666-1676 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Microfluidics
  • Molecules
  • Synaptic Transmission
  • Neurotransmitter Agents
  • Cell signaling

• Microbeam-coupled capillary electrophoresis

  Garty, G., Ehsan, M. U., Buonanno, M., Yang, Z., Sweedler, J. V. & Brenner, D. J., Sep 1 2015, In: Radiation Protection Dosimetry. 166, 1-4, p. 188-191 4 p., ncv148.

  Research output: Contribution to journal › Article › peer-review

  • Capillary Electrophoresis
  • microbeams
  • electrophoresis
  • charged particles
  • Reactive Oxygen Species

• Metrics to Evaluate Journals, Scientists, and Science: We Are Not There Yet

  Sweedler, J. V., Jun 6 2017, In: Analytical Chemistry. 89, 11, p. 5653 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Methodologies for metabolomics: Experimental strategies and techniques

  Lutz, N. W., Sweedler, J. V. & Wevers, R. A., Jan 1 2010, Cambridge University Press. 627 p.

  Research output: Book/Report/Conference proceeding › Book

  • Metabolomics
  • Metabolites
  • Metabolic Networks and Pathways
  • Mass spectrometry
  • Metabolism

• Meet the Analytical Chemistry editorial advisory board

  Sweedler, J. V., Feb 5 2013, In: Analytical chemistry. 85, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Meet our second advisory board, the analytical chemistry features panel

  Sweedler, J. V., Aug 20 2013, In: Analytical chemistry. 85, 16, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Mass spectrometry screening reveals peptides modulated differentially in the medial prefrontal cortex of rats with disparate initial sensitivity to cocaine

  Romanova, E. V., Lee, J. E., Kelleher, N. L., Sweedler, J. V. & Gulley, J. M., Sep 2010, In: AAPS Journal. 12, 3, p. 443-454 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass Screening
  • Cocaine
  • Prefrontal Cortex
  • Mass Spectrometry
  • Peptides

• Mass spectrometry imaging using the stretched sample approach

  Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., 2010, Mass Spectrometry Imaging: Principles and Protocols. Rubakhin, S. & Sweedler, J. (eds.). p. 465-479 15 p. (Methods in Molecular Biology; vol. 656).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Mass Spectrometry
  • Membranes
  • Lasers
  • Computer-Assisted Image Processing
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

• Mass spectrometry imaging of complex microbial communities

  Dunham, S. J. B., Ellis, J. F., Li, B. & Sweedler, J. V., 2017, In: Accounts of chemical research. 50, 1, p. 96-104 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Imaging techniques
  • Metabolomics
  • Microbiology
  • Metabolites

• Mass spectrometry imaging and GC-MS profiling of the mammalian peripheral sensory-motor circuit

  Rubakhin, S. S., Ulanov, A. & Sweedler, J. V., Jun 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 6, p. 958-966 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Spinal Ganglia
  • Mass Spectrometry
  • Imaging techniques
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

• Mass Spectrometry Imaging: Principles and Protocols

  Rubakhin, S. (ed.) & Sweedler, J. V. (ed.), 2010, Humana Press. 488 p. (Methods in Molecular Biology; vol. 656)

  Research output: Book/Report/Conference proceeding › Book

  • Mass Spectrometry
  • Xenobiotics
  • Industry
  • Molecular Biology
  • Technology

• Mass spectrometry–based methodologies for single-cell metabolite detection and identification

  Knolhoff, A. M., Nemes, P., Rubakhin, S. & Sweedler, J. V., Jan 1 2010, Methodologies for Metabolomics: Experimental Strategies and Techniques. Cambridge University Press, p. 119-139 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Metabolomics
  • Metabolites
  • Fluorescence
  • Neuroglia
  • Tissue

• Mass spectrometry-based characterization of endogenous peptides and metabolites in small volume samples

  Ong, T. H., Tillmaand, E. G., Makurath, M., Rubakhin, S. S. & Sweedler, J. V., Jul 1 2015, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1854, 7, p. 732-740 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolites
  • Mass spectrometry
  • Mass Spectrometry
  • Peptides
  • Assays

• MALDI MS Guided Liquid Microjunction Extraction for Capillary Electrophoresis-Electrospray Ionization MS Analysis of Single Pancreatic Islet Cells

  Comi, T. J., Makurath, M. A., Philip, M. C., Rubakhin, S. S. & Sweedler, J. V., Jul 18 2017, In: Analytical Chemistry. 89, 14, p. 7765-7772 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Ionization
  • Mass spectrometry
  • Desorption

• MALDI-guided SIMS: Multiscale imaging of metabolites in bacterial biofilms

  Lanni, E. J., Masyuko, R. N., Driscoll, C. M., Aerts, J. T., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Sep 1 2014, In: Analytical chemistry. 86, 18, p. 9139-9145 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary ion mass spectrometry
  • Metabolites
  • Biofilms
  • Ionization
  • Desorption

• Making the Editor's Job Easier: Let Us Know about Prior Submissions and Related Manuscripts

  Sweedler, J. V., Apr 18 2017, In: Analytical Chemistry. 89, 8, p. 4329 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Laminar stream of detergents for subcellular neurite damage in a microfluidic device: A simple tool for the study of neuroregeneration

  Lee, C. Y., Romanova, E. V. & Sweedler, J. V., Jun 2013, In: Journal of Neural Engineering. 10, 3, 036020.

  Research output: Contribution to journal › Article › peer-review

  • Lab-On-A-Chip Devices
  • Detergents
  • Neurites
  • Microfluidics
  • Neurons

• Interrogation of spatial metabolome of Ginkgo biloba with high-resolution matrix-assisted laser desorption/ionization and laser desorption/ionization mass spectrometry imaging

  Li, B., Neumann, E. K., Ge, J., Gao, W., Yang, H., Li, P. & Sweedler, J. V., Nov 2018, In: Plant Cell and Environment. 41, 11, p. 2693-2703 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo
  • Ginkgo biloba
  • metabolome
  • Metabolome
  • ionization

• Integration of untargeted metabolomics with transcriptomics reveals active metabolic pathways

  Cho, K., Evans, B. S., Wood, B. M. K., Kumar, R., Erb, T. J., Warlick, B. P., Gerlt, J. A. & Sweedler, J. V., Jun 1 2015, In: Metabolomics. 11, 3, p. 503-517 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolic Networks and Pathways
  • Salvaging
  • Methionine
  • Metabolites

• Improved identification and quantitation of mature endogenous peptides in the rodent hypothalamus using a rapid conductive sample heating system

  Yang, N., Anapindi, K. D. B., Romanova, E. V., Rubakhin, S. S. & Sweedler, J. V., Dec 7 2017, In: Analyst. 142, 23, p. 4476-4485 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptides
  • Heating
  • rodent
  • peptide
  • Neuropeptides

• Identification of best indicators of peptide-spectrum match using a permutation resampling approach

  Akhtar, M. N., Southey, B. R., Andrén, P. E., Sweedler, J. V. & Rodriguez-Zas, S. L., Oct 30 2014, In: Journal of Bioinformatics and Computational Biology. 12, 5, 1440001.

  Research output: Contribution to journal › Article › peer-review

  • Peptides
  • Databases
  • Software

• Help your institutions reputation and publish in analytical chemistry

  Sweedler, J. V., Feb 3 2015, In: Analytical chemistry. 87, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Genome-wide census and expression profiling of chicken neuropeptide and prohormone convertase genes

  Delfino, K. R., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., Feb 2010, In: Neuropeptides. 44, 1, p. 31-44 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Proprotein Convertases
  • Censuses
  • Neuropeptides
  • Chickens
  • Genome