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• MALDI-guided SIMS: Multiscale imaging of metabolites in bacterial biofilms

  Lanni, E. J., Masyuko, R. N., Driscoll, C. M., Aerts, J. T., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Sep 1 2014, In: Analytical Chemistry. 86, 18, p. 9139-9145 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary ion mass spectrometry
  • Metabolites
  • Biofilms
  • Ionization
  • Desorption

• MALDI mass spectrometry imaging of neuronal cell cultures

  Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 2011, In: Journal of the American Society for Mass Spectrometry. 22, 5, p. 828-836 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell culture
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Aplysia
  • Mass Spectrometry

• Mass spectrometry-based characterization of endogenous peptides and metabolites in small volume samples

  Ong, T. H., Tillmaand, E. G., Makurath, M., Rubakhin, S. S. & Sweedler, J. V., Jul 1 2015, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1854, 7, p. 732-740 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolites
  • Mass spectrometry
  • Mass Spectrometry
  • Peptides
  • Assays

• Mass spectrometry imaging and GC-MS profiling of the mammalian peripheral sensory-motor circuit

  Rubakhin, S. S., Ulanov, A. & Sweedler, J. V., Jun 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 6, p. 958-966 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Spinal Ganglia
  • Mass Spectrometry
  • Imaging techniques
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

• Mass spectrometry imaging and identification of peptides associated with cephalic ganglia regeneration in Schmidtea mediterranea

  Ong, T. H., Romanova, E. V., Roberts-Galbraith, R. H., Yang, N., Zimmerman, T. A., Collins, J. J., Lee, J. E., Kelleher, N. L., Newmark, P. A. & Sweedler, J. V., Apr 8 2016, In: Journal of Biological Chemistry. 291, 15, p. 8109-8120 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Ganglia
  • Mass Spectrometry
  • Regeneration
  • Head

• Mass spectrometry of proteins

  Romanova, E. V., Annangudi, S. P., Tai, H. C. & Sweedler, J. V., Jan 1 2016, The Curated Reference Collection in Neuroscience and Biobehavioral Psychology. Elsevier Science Ltd., p. 681-687 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Mass Spectrometry
  • Proteins
  • Molecular Probes
  • Post Translational Protein Processing
  • Biomarkers

• Meet our second advisory board, the analytical chemistry features panel

  Sweedler, J. V., Aug 20 2013, In: Analytical chemistry. 85, 16, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Meet the Analytical Chemistry editorial advisory board

  Sweedler, J. V., Feb 5 2013, In: Analytical chemistry. 85, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry

  Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Sep 1 2011, In: Analytical chemistry. 83, 17, p. 6810-6817 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Mass spectrometry
  • Neurons
  • Metabolites

• Metal-assisted polyatomic SIMS and laser desorption/ionization for enhanced small molecule imaging of bacterial biofilms

  Dunham, S. J. B., Comi, T. J., Ko, K., Li, B., Baig, N. F., Morales-Soto, N., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Jun 1 2016, In: Biointerphases. 11, 2, 02A325.

  Research output: Contribution to journal › Article › peer-review

  • Secondary Ion Mass Spectrometry
  • Secondary ion mass spectrometry
  • biofilms
  • Biofilms
  • Ionization

• Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord

  Miller, L. K., Hou, X., Rodriguiz, R. M., Gagnidze, K., Sweedler, J. V., Wetsel, W. C. & Devi, L. A., Dec 2011, In: Journal of Neurochemistry. 119, 5, p. 1074-1085 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin-Converting Enzymes
  • Morphine
  • Spinal Cord
  • Peptides
  • Neuropeptides

• Microbeam-coupled capillary electrophoresis

  Garty, G., Ehsan, M. U., Buonanno, M., Yang, Z., Sweedler, J. V. & Brenner, D. J., Sep 1 2015, In: Radiation Protection Dosimetry. 166, 1-4, p. 188-191 4 p., ncv148.

  Research output: Contribution to journal › Article › peer-review

  • Capillary Electrophoresis
  • microbeams
  • electrophoresis
  • charged particles
  • Reactive Oxygen Species

• Microfluidic systems for studying neurotransmitters and neurotransmission

  Croushore, C. A. & Sweedler, J. V., May 7 2013, In: Lab on a chip. 13, 9, p. 1666-1676 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Microfluidics
  • Molecules
  • Synaptic Transmission
  • Neurotransmitter Agents
  • Cell signaling

• Model of ion intensity from tandem mass spectra for improved peptide identification and simulation

  Fazal, Z., Southey, B. R., Sadeque, A., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 994-996 3 p. 6112534. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Peptides
  • Ions
  • Mass spectrometry
  • Protons
  • Tandem Mass Spectrometry

• Molecular and Physiological Characterization of a Receptor for d -Amino Acid-Containing Neuropeptides

  Checco, J. W., Zhang, G., Yuan, W. D., Yu, K., Yin, S. Y., Roberts-Galbraith, R. H., Yau, P. M., Romanova, E. V., Jing, J. & Sweedler, J. V., May 18 2018, In: ACS chemical biology. 13, 5, p. 1343-1352 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Receptors
  • Neuropeptides
  • Neuropeptide Receptors
  • Amino Acids
  • Aplysia

• Molecular organization of drosophila neuroendocrine cells by dimmed

  Park, D., Hadžić, T., Yin, P., Rusch, J., Abruzzi, K., Rosbash, M., Skeath, J. B., Panda, S., Sweedler, J. V. & Taghert, P. H., Sep 27 2011, In: Current Biology. 21, 18, p. 1515-1524 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroendocrine Cells
  • Drosophila
  • Assays
  • Secretory Vesicles
  • cytochrome b561

• Multifactorial understanding of ion abundance in tandem mass spectrometry experiments

  Fazal, Z., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., 2013, In: Journal of Proteomics and Bioinformatics. 6, 2, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Ions
  • Peptides
  • Experiments

• Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging

  Neumann, E. K., Comi, T. J., Spegazzini, N., Mitchell, J. W., Rubakhin, S. S., Gillette, M. U., Bhargava, R. & Sweedler, J. V., Oct 2 2018, In: Analytical Chemistry. 90, 19, p. 11572-11580 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Infrared radiation
  • Brain
  • Imaging techniques
  • Chemical analysis

• Multimodal chemical imaging of molecular messengers in emerging Pseudomonas aeruginosa bacterial communities

  Baig, N. F., Dunham, S. J. B., Morales-Soto, N., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 7 2015, In: Analyst. 140, 19, p. 6544-6552 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Multimodal Imaging
  • Biofilms
  • Pseudomonas aeruginosa
  • biofilm
  • Oxides

• Nanopipet-based liquid-liquid interface probes for the electrochemical detection of acetylcholine, tryptamine, and serotonin via ionic transfer

  Colombo, M. L., Sweedler, J. V. & Shen, M., May 19 2015, In: Analytical Chemistry. 87, 10, p. 5095-5100 6 p.

  Research output: Contribution to journal › Article › peer-review

  • tryptamine
  • Acetylcholine
  • Serotonin
  • Electrodes
  • Liquids

• Neuropeptidomics: Mass spectrometry-based qualitative and quantitative analysis

  Yin, P., Hou, X., Romanova, E. V. & Sweedler, J. V., 2011, Neuropeptides: Methods and Protocols. Merighi, A. (ed.). p. 223-236 14 p. (Methods in Molecular Biology; vol. 789).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neuropeptides
  • Mass Spectrometry
  • Liquid Chromatography
  • Peptides
  • Protein Precursors

• Neuropeptidomics

  Sweedler, J. V., Xie, F. & Bora, A., Sep 23 2011, Protein and Peptide Mass Spectrometry in Drug Discovery. John Wiley and Sons, p. 393-433 41 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Neuropeptidomics of the mammalian brain

  Xie, F., Romanova, E. V. & Sweedler, J. V., Jun 3 2011, Neuroproteomics. Li, K. W. (ed.). p. 229-242 14 p. (Neuromethods; vol. 57).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Brain
  • Mass spectrometry
  • Peptides
  • Mass Spectrometry
  • Liquid chromatography

• Neuropeptidomics of the Rat Habenular Nuclei

  Yang, N., Anapindi, K. D. B., Rubakhin, S. S., Wei, P., Yu, Q., Li, L., Kenny, P. J. & Sweedler, J. V., Apr 6 2018, In: Journal of Proteome Research. 17, 4, p. 1463-1473 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Habenula
  • Mass spectrometry
  • Rats
  • Tandem Mass Spectrometry
  • Neuropeptides

• Newly Identified Aplysia SPTR-Gene Family-Derived Peptides: Localization and Function

  Zhang, G., Yuan, W. D., Vilim, F. S., Romanova, E. V., Yu, K., Yin, S. Y., Le, Z. W., Xue, Y. Y., Chen, T. T., Chen, G. K., Chen, S. A., Cropper, E. C., Sweedler, J. V., Weiss, K. R. & Jing, J., Aug 15 2018, In: ACS Chemical Neuroscience. 9, 8, p. 2041-2053 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Aplysia
  • Interneurons
  • Genes
  • Cheek
  • Peptides

• New Mass Spectrometric Approaches for Uncovering Neuropeptides

  Hou, X. & Sweedler, J. V., Aug 29 2013, Handbook of Biologically Active Peptides. Elsevier Inc., p. 1749-1756 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Nominate Outstanding Measurement Scientists for the 2020 Analytical Chemistry Young Innovator and the 2021 Advances in Measurement Science Lectureship Awards!

  Sweedler, J. V., Mar 3 2020, In: Analytical Chemistry. 92, 5, p. 3493 1 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Non-targeted identification of d-amino acid-containing peptides through enzymatic screening, chiral amino acid analysis, and LC-MS

  Tai, H. C., Checco, J. W. & Sweedler, J. V., 2018, Methods in Molecular Biology. Humana Press Inc., p. 107-118 12 p. (Methods in Molecular Biology; vol. 1719).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amino Acids
  • Peptides
  • Post Translational Protein Processing
  • Mass Spectrometry
  • Animals

• On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues

  Wu, Q., Comi, T. J., Li, B., Rubakhin, S. S. & Sweedler, J. V., Jun 7 2016, In: Analytical Chemistry. 88, 11, p. 5988-5995 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Rats
  • Desorption
  • Fatty Acids

• Optically Guided Single Cell Mass Spectrometry of Rat Dorsal Root Ganglia to Profile Lipids, Peptides and Proteins

  Do, T. D., Ellis, J. F., Neumann, E. K., Comi, T. J., Tillmaand, E. G., Lenhart, A. E., Rubakhin, S. S. & Sweedler, J. V., May 22 2018, In: ChemPhysChem. 19, 10, p. 1180-1191 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Rats
  • peptides
  • rats
  • lipids

• Our editorial team

  Sweedler, J. V., Jun 2 2015, In: Analytical chemistry. 87, 11, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Our evolving editorial team

  Sweedler, J. V., Sep 6 2016, In: Analytical Chemistry. 88, 17, p. 8347 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization

  Aerts, J. T., Louis, K. R., Crandall, S. R., Govindaiah, G., Cox, C. L. & Sweedler, J. V., Mar 18 2014, In: Analytical Chemistry. 86, 6, p. 3203-3208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillary electrophoresis
  • Metabolomics
  • Electrophysiology
  • Mass spectrometry
  • Clamping devices

• Peptide identifications and false discovery rates using different mass spectrometry platforms

  Anapindi, K. D. B., Romanova, E. V., Southey, B. R. & Sweedler, J. V., May 15 2018, In: Talanta. 182, p. 456-463 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Peptides
  • Neuropeptides
  • Protein Precursors
  • Bioinformatics

• Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System

  Tillmaand, E. G., Yang, N., Kindt, C. A. C., Romanova, E. V., Rubakhin, S. S. & Sweedler, J. V., Dec 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 12, p. 2051-2061 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Spinal Ganglia
  • Mass spectrometry
  • Peptides
  • Spinal Nerve Roots
  • Mass Spectrometry

• Peptidomics for the discovery and characterization of neuropeptides and hormones

  Romanova, E. V. & Sweedler, J. V., Sep 12 2015, In: Trends in Pharmacological Sciences. 36, 9, p. 579-586 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neuropeptides
  • G-Protein-Coupled Receptors
  • Hormones
  • Orphaned Children
  • Mass spectrometry

• Pittcon: Still vibrant after more than 60 years

  Sweedler, J. V., Mar 5 2013, In: Analytical chemistry. 85, 5, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Please Welcome John Yates, III as Editor of the Journal of Proteome Research

  Sweedler, J. V., Apr 1 2016, In: Journal of Proteome Research. 15, 4, p. 1115 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

  Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In: mBio. 5, 1, e00933-13.

  Research output: Contribution to journal › Article › peer-review

  • stachydrine
  • Betaine
  • Paracoccus denitrificans
  • Hydroxyproline
  • Metabolomics

• Probing the production of amidated peptides following genetic and dietary copper manipulations

  Yin, P., Bousquet-Moore, D., Annangudi, S. P., Southey, B. R., Mains, R. E., Eipper, B. A. & Sweedler, J. V., Dec 16 2011, In: PloS one. 6, 12, e28679.

  Research output: Contribution to journal › Article › peer-review

  • peptidylglycine monooxygenase
  • Mixed Function Oxygenases
  • Copper
  • copper
  • peptides

• Profiling metabolites and peptides in single cells

  Rubakhin, S. S., Romanova, E. V., Nemes, P. & Sweedler, J. V., Apr 2011, In: Nature Methods. 8, 4, p. S20-S29

  Research output: Contribution to journal › Article › peer-review

  • Metabolites
  • Developmental Biology
  • Cytology
  • Stem cells
  • Microanalysis

• Progress toward single cell metabolomics

  Rubakhin, S. S., Lanni, E. J. & Sweedler, J. V., Feb 2013, In: Current Opinion in Biotechnology. 24, 1, p. 95-104 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolomics
  • Metabolites
  • Molecules
  • Mass spectrometry
  • Microfluidics

• Publish only your original research

  Sweedler, J. V., Apr 1 2014, In: Analytical chemistry. 86, 7, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry

  Nemes, P., Rubakhin, S. S., Aerts, J. T. & Sweedler, J. V., Apr 2013, In: Nature Protocols. 8, 4, p. 783-799 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Metabolomics
  • Electrospray Ionization Mass Spectrometry
  • Capillary Electrophoresis

• Quantitation of endogenous peptides using mass spectrometry based methods

  Romanova, E. V., Dowd, S. E. & Sweedler, J. V., Oct 2013, In: Current Opinion in Chemical Biology. 17, 5, p. 801-808 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Mass spectrometry
  • Mass Spectrometry
  • Peptides
  • Molecular interactions
  • Industrial Development

• Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models

  Tillmaand, E. G., Anapindi, K. D. B., De La Toba, E. A., Guo, C. J., Krebs, J., Lenhart, A. E., Liu, Q. & Sweedler, J. V., Mar 6 2020, In: Journal of Proteome Research. 19, 3, p. 1248-1257 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Spinal Cord Dorsal Horn
  • Spinal Ganglia
  • Neuropeptides
  • Peptides
  • Atopic Dermatitis

• Quantitative Imprint Mass Spectrometry Imaging of Endogenous Ceramides in Rat Brain Tissue with Kinetic Calibration

  Wu, Q., Rubakhin, S. S. & Sweedler, J. V., May 5 2020, In: Analytical chemistry. 92, 9, p. 6613-6621 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Ceramides
  • Rats
  • Tissue
  • Brain

• Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus

  Lee, J. E., Zamdborg, L., Southey, B. R., Atkins, N., Mitchell, J. W., Li, M., Gillette, M. U., Kelleher, N. L. & Sweedler, J. V., Feb 1 2013, In: Journal of Proteome Research. 12, 2, p. 585-593 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Suprachiasmatic Nucleus
  • Rats
  • Peptides
  • Mammals
  • Optic Chiasm

• Quantitative reflection imaging of fixed aplysia californica pedal ganglion neurons on nanostructured plasmonic crystals

  Le, A. P., Kang, S., Thompson, L. B., Rubakhin, S. S., Sweedler, J. V., Rogers, J. A. & Nuzzo, R. G., Nov 4 2013, In: Journal of Physical Chemistry B. 117, 42, p. 13069-13081 13 p.

  Research output: Contribution to journal › Article › peer-review

  • pedals
  • Surface plasmon resonance
  • Plasmonics
  • neurons
  • Crystals

• Quantitative SIMS Imaging of Agar-Based Microbial Communities

  Dunham, S. J. B., Ellis, J. F., Baig, N. F., Morales-Soto, N., Cao, T., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., May 1 2018, In: Analytical Chemistry. 90, 9, p. 5654-5663 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary ion mass spectrometry
  • Agar
  • Imaging techniques
  • Biofilms
  • Ions