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• Non-targeted identification of d-amino acid-containing peptides through enzymatic screening, chiral amino acid analysis, and LC-MS

  Tai, H. C., Checco, J. W. & Sweedler, J. V., 2018, Methods in Molecular Biology. Humana Press Inc., p. 107-118 12 p. (Methods in Molecular Biology; vol. 1719).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amino Acids
  • Peptides
  • Post Translational Protein Processing
  • Mass Spectrometry
  • Animals

• Now it is a highlight, not an acceleration

  Sweedler, J. V., Sep 4 2012, In: Analytical chemistry. 84, 17, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues

  Wu, Q., Comi, T. J., Li, B., Rubakhin, S. S. & Sweedler, J. V., Jun 7 2016, In: Analytical Chemistry. 88, 11, p. 5988-5995 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Rats
  • Desorption
  • Fatty Acids

• Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens

  Zhang, P., Moye, L. S., Southey, B. R., Dripps, I., Sweedler, J. V., Pradhan, A. & Rodriguez-Zas, S. L., Dec 1 2019, In: Molecular Neurobiology. 56, 12, p. 7929-7949 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Trigeminal Nuclei
  • Trigeminal Ganglion
  • Hyperalgesia
  • Nucleus Accumbens
  • Circadian Rhythm

• Optically Guided Single Cell Mass Spectrometry of Rat Dorsal Root Ganglia to Profile Lipids, Peptides and Proteins

  Do, T. D., Ellis, J. F., Neumann, E. K., Comi, T. J., Tillmaand, E. G., Lenhart, A. E., Rubakhin, S. S. & Sweedler, J. V., May 22 2018, In: ChemPhysChem. 19, 10, p. 1180-1191 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Rats
  • peptides
  • rats
  • lipids

• Our evolving editorial team

  Sweedler, J. V., Sep 6 2016, In: Analytical Chemistry. 88, 17, p. 8347 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• PACAP and other neuropeptide targets link chronic migraine and opioid-induced hyperalgesia in mouse models

  Anapindi, K. D. B., Yang, N., Romanova, E. V., Rubakhin, S. S., Tipton, A., Dripps, I., Sheets, Z., Sweedler, J. V. & Pradhan, A. A., 2019, In: Molecular and Cellular Proteomics. 18, 12, p. 2447-2458 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Hyperalgesia
  • Neuropeptides
  • Migraine Disorders
  • Opioid Analgesics

• Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization

  Aerts, J. T., Louis, K. R., Crandall, S. R., Govindaiah, G., Cox, C. L. & Sweedler, J. V., 2014, In: Analytical chemistry. 86, 6, p. 3203-3208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillary electrophoresis
  • Metabolomics
  • Electrophysiology
  • Mass spectrometry
  • Clamping devices

• Peptide identifications and false discovery rates using different mass spectrometry platforms

  Anapindi, K. D. B., Romanova, E. V., Southey, B. R. & Sweedler, J. V., May 15 2018, In: Talanta. 182, p. 456-463 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Peptides
  • Neuropeptides
  • Protein Precursors
  • Bioinformatics

• Peptidomic analyses of mouse astrocytic cell lines and rat primary cultured astrocytes

  Yin, P., Knolhoff, A. M., Rosenberg, H. J., Millet, L. J., Gillette, M. U. & Sweedler, J. V., Aug 3 2012, In: Journal of Proteome Research. 11, 8, p. 3965-3973 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Astrocytes
  • Rats
  • Cells
  • Peptides
  • Cell Line

• Please Welcome John Yates, III as Editor of the Journal of Proteome Research

  Sweedler, J. V., Apr 1 2016, In: Journal of Proteome Research. 15, 4, p. 1115 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

  Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In: mBio. 5, 1, e00933-13.

  Research output: Contribution to journal › Article › peer-review

  • stachydrine
  • Betaine
  • Paracoccus denitrificans
  • Hydroxyproline
  • Metabolomics

• Probing the production of amidated peptides following genetic and dietary copper manipulations

  Yin, P., Bousquet-Moore, D., Annangudi, S. P., Southey, B. R., Mains, R. E., Eipper, B. A. & Sweedler, J. V., Dec 16 2011, In: PloS one. 6, 12, e28679.

  Research output: Contribution to journal › Article › peer-review

  • peptidylglycine monooxygenase
  • Mixed Function Oxygenases
  • Copper
  • copper
  • peptides

• Professional Editors or Scientist Editors? Both perspectives have value.

  Sweedler, J. V., Mar 6 2012, In: Analytical chemistry. 84, 5, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Profiling metabolites and peptides in single cells

  Rubakhin, S. S., Romanova, E. V., Nemes, P. & Sweedler, J. V., Apr 2011, In: Nature Methods. 8, 4, p. S20-S29

  Research output: Contribution to journal › Article › peer-review

  • Metabolites
  • Developmental Biology
  • Cytology
  • Stem cells
  • Microanalysis

• Profiling of Microbial Colonies for High-Throughput Engineering of Multistep Enzymatic Reactions via Optically Guided Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

  Si, T., Li, B., Comi, T. J., Wu, Y., Hu, P., Wu, Y., Min, Y., Mitchell, D. A., Zhao, H. & Sweedler, J. V., 2017, In: Journal of the American Chemical Society. 139, 36, p. 12466-12473 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Desorption
  • ionization

• Publish only your original research

  Sweedler, J. V., Apr 1 2014, In: Analytical chemistry. 86, 7, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models

  Tillmaand, E. G., Anapindi, K. D. B., De La Toba, E. A., Guo, C. J., Krebs, J., Lenhart, A. E., Liu, Q. & Sweedler, J. V., Mar 6 2020, In: Journal of Proteome Research. 19, 3, p. 1248-1257 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Spinal Cord Dorsal Horn
  • Spinal Ganglia
  • Neuropeptides
  • Peptides
  • Atopic Dermatitis

• Quantitative Imprint Mass Spectrometry Imaging of Endogenous Ceramides in Rat Brain Tissue with Kinetic Calibration

  Wu, Q., Rubakhin, S. S. & Sweedler, J. V., May 5 2020, In: Analytical chemistry. 92, 9, p. 6613-6621 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Ceramides
  • Rats
  • Tissue
  • Brain

• Quantitative Reflection Imaging for the Morphology and Dynamics of Live Aplysia californica Pedal Ganglion Neurons Cultured on Nanostructured Plasmonic Crystals

  Kang, S., Badea, A., Rubakhin, S. S., Sweedler, J. V., Rogers, J. A. & Nuzzo, R. G., Sep 5 2017, In: Langmuir. 33, 35, p. 8640-8650 11 p.

  Research output: Contribution to journal › Article › peer-review

  • pedals
  • Plasmonics
  • Polyelectrolytes
  • neurons
  • Crystals

• Quantitative SIMS Imaging of Agar-Based Microbial Communities

  Dunham, S. J. B., Ellis, J. F., Baig, N. F., Morales-Soto, N., Cao, T., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., May 1 2018, In: Analytical Chemistry. 90, 9, p. 5654-5663 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary ion mass spectrometry
  • Agar
  • Imaging techniques
  • Biofilms
  • Ions

• Rapid Screening of Lanthipeptide Analogs via In-Colony Removal of Leader Peptides in Escherichia coli

  Si, T., Tian, Q., Min, Y., Zhang, L., Sweedler, J. V., Van Der Donk, W. A. & Zhao, H., Sep 26 2018, In: Journal of the American Chemical Society. 140, 38, p. 11884-11888 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Sorting Signals
  • Escherichia coli
  • peptide
  • Screening
  • screening

• Rejections with editorial expertise and without external review: Are these fair?

  Sweedler, J. V., Dec 4 2012, In: Analytical chemistry. 84, 23, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Relative quantitation of neuropeptides over a thousand-fold concentration range

  Hou, X., Xie, F. & Sweedler, J. V., Dec 2012, In: Journal of the American Society for Mass Spectrometry. 23, 12, p. 2083-2093 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Neuropeptides
  • Mass Spectrometry
  • Electrospray ionization
  • Ionization

• Removing Formaldehyde-Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin-Fixed Paraffin-Embedded Tissues

  Lee, D. K., Rubakhin, S. S., Kusmartseva, I., Wasserfall, C., Atkinson, M. A. & Sweedler, J. V., Dec 7 2020, In: Angewandte Chemie - International Edition. 59, 50, p. 22584-22590 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Hormones
  • Mass spectrometry
  • Formaldehyde
  • Paraffins
  • Paraffin

• Reproducibility and Replicability

  Sweedler, J. V., Jul 2 2019, In: Analytical chemistry. 91, 13, p. 7971-7972 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Reviews, perspectives, features: What's the difference?

  Sweedler, J. V., Feb 7 2012, In: Analytical chemistry. 84, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Safety: Declare the Hidden Risks and Hazards of Your Research

  Sweedler, J. V., 2016, In: Analytical Chemistry. 88, 23, p. 11261 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Salami Publications and Duplicate Submissions: Put Them on Your List of Things to Avoid

  Sweedler, J. V., Mar 5 2019, In: Analytical chemistry. 91, 5, p. 3177-3178 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Sampling techniques for single-cell electrophoresis

  Cecala, C. & Sweedler, J. V., Jul 7 2012, In: Analyst. 137, 13, p. 2922-2929 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Electrophoresis
  • sampling technique
  • electrokinesis
  • Sampling
  • Fluorescence

• Science Communication: A Science Not an Art

  Sweedler, J. V., Mar 7 2017, In: Analytical Chemistry. 89, 5, p. 2645 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Science Research - Looking in the Mirror

  Sweedler, J. V., Nov 6 2018, In: Analytical Chemistry. 90, 21, p. 12323-12324 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Seasonal adaptations of the hypothalamo-neurohypophyseal system of the dromedary camel

  Alim, F. Z. D., Romanova, E. V., Tay, Y. L., Rahman, A. Y. B. A., Chan, K. G., Hong, K. W., Rogers, M., Southey, B. R., Greenwood, M. P., Mecawi, A. S., Mustafa, M. R., Mahy, N., Campbell, C., Antunes-Rodrigues, J., Sweedler, J. V., Murphy, D. & Hindmarch, C. C. T., Jun 2019, In: PloS one. 14, 6, e0216679.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Camelus
  • Camelus dromedarius
  • Neuropeptides
  • arginine vasopressin
  • neuropeptides

• Secondary ion mass spectrometry imaging of molecular distributions in cultured neurons and their processes: Comparative analysis of sample preparation

  Tucker, K. R., Li, Z., Rubakhin, S. S. & Sweedler, J. V., Nov 2012, In: Journal of the American Society for Mass Spectrometry. 23, 11, p. 1931-1938 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary Ion Mass Spectrometry
  • Secondary ion mass spectrometry
  • Molecular Imaging
  • Neurons
  • Imaging techniques

• Serotonin of mast cell origin contributes to hippocampal function

  Nautiyal, K. M., Dailey, C. A., Jahn, J. L., Rodriquez, E., Son, N. H., Sweedler, J. V. & Silver, R., Aug 2012, In: European Journal of Neuroscience. 36, 3, p. 2347-2359 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Mast Cells
  • Serotonin
  • Neurogenesis
  • Hippocampus
  • Fluoxetine

• Single-cell analysis at the threshold

  Chen, X., Love, J. C., Navin, N. E., Pachter, L., Stubbington, M. J. T., Svensson, V., Sweedler, J. V. & Teichmann, S. A., Nov 8 2016, In: Nature Biotechnology. 34, 11, p. 1111-1118 8 p.

  Research output: Contribution to journal › Review article › peer-review

• Single-Cell Classification Using Mass Spectrometry through Interpretable Machine Learning

  Xie, Y. R., Castro, D. C., Bell, S. E., Rubakhin, S. & Sweedler, J. V., Jul 7 2020, In: Analytical chemistry. 92, 13, p. 9338-9347 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Astrocytes
  • Machine learning
  • Biochemistry
  • Mass spectrometers

• Single-cell metabolomics: Changes in the metabolome of freshly isolated and cultured neurons

  Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Oct 17 2012, In: ACS Chemical Neuroscience. 3, 10, p. 782-792 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolome
  • Neurons
  • Glycerol
  • Metabolites

• Single Cell Neurometabolomics

  Qi, M., Philip, M. C., Yang, N. & Sweedler, J. V., Jan 17 2018, In: ACS Chemical Neuroscience. 9, 1, p. 40-50 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolomics
  • Molecules
  • Astrocytes
  • Brain
  • Metabolites

• Single Cell Peptide Heterogeneity of Rat Islets of Langerhans

  Jansson, E. T., Comi, T. J., Rubakhin, S. S. & Sweedler, J. V., Sep 16 2016, In: ACS chemical biology. 11, 9, p. 2588-2595 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Polypeptide
  • Rats
  • Islets of Langerhans
  • Peptides
  • neuropeptide Y4 receptor

• Single Cell Profiling Using Ionic Liquid Matrix-Enhanced Secondary Ion Mass Spectrometry for Neuronal Cell Type Differentiation

  Do, T. D., Comi, T. J., Dunham, S. J. B., Rubakhin, S. S. & Sweedler, J. V., Mar 7 2017, In: Analytical Chemistry. 89, 5, p. 3078-3086 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionic Liquids
  • Secondary ion mass spectrometry
  • Phosphatidylcholines
  • Lipids
  • Rats

• Single Synaptic Observation of Cholinergic Neurotransmission on Living Neurons: Concentration and Dynamics

  Shen, M., Qu, Z., Deslaurier, J., Welle, T. M., Sweedler, J. V. & Chen, R., Jun 27 2018, In: Journal of the American Chemical Society. 140, 25, p. 7764-7768 5 p.

  Research output: Contribution to journal › Article › peer-review

  • in situ measurement
  • Synaptic Transmission
  • Cholinergic Agents
  • Acetylcholine
  • Neurons

• Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry

  Amaya, K. R., Sweedler, J. V. & Clayton, D. F., Aug 2011, In: Journal of Neurochemistry. 118, 4, p. 499-511 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary Ion Mass Spectrometry
  • Secondary ion mass spectrometry
  • Finches
  • Equidae
  • Music

• Small-Volume Analysis of Cell-Cell Signaling Molecules in the Brain

  Romanova, E. V., Aerts, J. T., Croushore, C. A. & Sweedler, J. V., Jan 2014, In: Neuropsychopharmacology. 39, 1, p. 50-64 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Size
  • Brain
  • Nervous System
  • Technology
  • Drug Discovery

• So you want to be a principal investigator?

  Sweedler, J. V., Aug 5 2014, In: Analytical chemistry. 86, 15, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Spatially dependent alkyl quinolone signaling responses to antibiotics in Pseudomonas aeruginosa swarms

  Morales-Soto, N., Dunham, S. J. B., Baig, N. F., Ellis, J. F., Madukoma, C. S., Bohn, P. W., Sweedler, J. V. & Shrout, J. D., Jun 15 2018, In: Journal of Biological Chemistry. 293, 24, p. 9544-9552 9 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-heptyl-3-hydroxy-4-quinolone
  • Hydroxyquinolines
  • Quinolones
  • Tobramycin
  • Pseudomonas aeruginosa

• Spatial organization of pseudomonas aeruginosa biofilms probed by combined matrix-assisted laser desorption ionization mass spectrometry and confocal raman microscopy

  Masyuko, R. N., Lanni, E. J., Driscoll, C. M., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 15 2014, In: Analyst. 139, 22, p. 5700-5708 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Biofilms
  • Ionization
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Desorption

• Spatiotemporal distribution of Pseudomonas aeruginosa alkyl quinolones under metabolic and competitive stress

  Cao, T., Sweedler, J. V., Bohn, P. W. & Shrout, J. D., Jul 1 2020, In: mSphere. 5, 4, e00426-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2-heptyl-3-hydroxy-4-quinolone
  • Physiological Stress
  • Quinolones
  • Pseudomonas aeruginosa
  • 2-(n-heptyl)-4-hydroxyquinoline N-oxide

• Spatiotemporal dynamics of molecular messaging in bacterial co-cultures studied by multimodal chemical imaging

  Cao, T., Morales-Soto, N., Jia, J., Baig, N. F., Dunham, S. J. B., Ellis, J., Sweedler, J. V., Shrout, J. D. & Bohn, P. W., Jan 1 2019, Photonic Diagnosis and Treatment of Infections and Inflammatory Diseases II. Dai, T., Popp, J. & Wu, M. X. (eds.). SPIE, 108630A. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10863).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Co-culture
  • Quorum Sensing
  • Imaging
  • Microscopic examination
  • Imaging techniques

• Strange Advice for Authors: Submit Your Manuscript with a Short Title on a Weekday

  Sweedler, J. V., Feb 4 2020, In: Analytical Chemistry. 92, 3, p. 2351-2352 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access