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2020
MicroRNA-210 Promotes Bile Acid–Induced Cholestatic Liver Injury by Targeting Mixed-Lineage Leukemia-4 Methyltransferase in Mice
Kim, Y. C., Jung, H., Seok, S., Zhang, Y., Ma, J., Li, T., Kemper, B. & Kemper, J. K., Jun 1 2020, In: Hepatology. 71, 6, p. 2118-2134 17 p.Research output: Contribution to journal › Article › peer-review
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2017
A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy
Byun, S., Kim, Y. C., Zhang, Y., Kong, B., Guo, G., Sadoshima, J., Ma, J., Kemper, B. & Kemper, J. K., Jun 14 2017, In: EMBO Journal. 36, 12, p. 1755-1769 15 p.Research output: Contribution to journal › Article › peer-review
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2020
Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A
Kim, Y-C., Seok, S., Zhang, Y., Ma, J., Kong, B., Guo, G., Kemper, B. & Kemper, J. K., Dec 2020, In: Nature communications. 11, 1, 5969.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Obesity-linked phosphorylation of SIRT1 by casein kinase 2 inhibits its nuclear localization and promotes fatty liver
Choi, S. E., Kwon, S., Seok, S., Xiao, Z., Lee, K. W., Kang, Y., Li, X., Shinoda, K., Kajimura, S., Kemper, B. & Kemper, J. K., Aug 1 2017, In: Molecular and cellular biology. 37, 15, e00006-17.Research output: Contribution to journal › Article › peer-review
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2018
Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid ß-oxidation
Seok, S., Kim, Y. C., Byun, S., Choi, S., Xiao, Z., Iwamori, N., Zhang, Y., Wang, C., Ma, J., Ge, K., Kemper, B. & Kemper, J. K., Jul 2 2018, In: Journal of Clinical Investigation. 128, 7, p. 3144-3159 16 p.Research output: Contribution to journal › Article › peer-review
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2020
Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase
Byun, S., Seok, S., Kim, Y. C., Zhang, Y., Yau, P., Iwamori, N., Xu, H. E., Ma, J., Kemper, B. & Kemper, J. K., Dec 1 2020, In: Nature communications. 11, 1, 807.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling–activated Src maintains cholesterol levels and protects from atherosclerosis
Byun, S., Jung, H., Chen, J., Kim, Y. C., Kim, D. H., Kong, B., Guo, G., Kemper, B. & Kemper, J. K., May 31 2019, In: Journal of Biological Chemistry. 294, 22, p. 8732-8744 13 p.Research output: Contribution to journal › Article › peer-review
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2020
Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver
Seok, S., Sun, H., Kim, Y-C., Kemper, B. & Kemper, J. K., Dec 16 2020, (E-pub ahead of print) In: Diabetes.Research output: Contribution to journal › Article › peer-review
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2018
Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis
Byun, S., Kim, D. H., Ryerson, D., Kim, Y. C., Sun, H., Kong, B., Yau, P., Guo, G., Eric Xu, H., Kemper, B. & Kemper, J. K., Dec 1 2018, In: Nature communications. 9, 1, 2590.Research output: Contribution to journal › Article › peer-review
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2019
Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption
Kim, Y. C., Byun, S., Seok, S., Guo, G., Xu, H. E., Kemper, B. & Kemper, J. K., Mar 2019, In: Gastroenterology. 156, 4, p. 1052-1065 14 p.Research output: Contribution to journal › Article › peer-review
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2018
AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
Kim, Y. C., Seok, S., Byun, S., Kong, B., Zhang, Y., Guo, G., Xie, W., Ma, J., Kemper, B. & Kemper, J. K., Dec 1 2018, In: Nature communications. 9, 1, 540.Research output: Contribution to journal › Article › peer-review
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2017
Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3
Kwon, S., Seok, S., Yau, P., Li, X., Kemper, B. & Kemper, J. K., Oct 20 2017, In: Journal of Biological Chemistry. 292, 42, p. 17312-17323 12 p.Research output: Contribution to journal › Article › peer-review