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• 2021

  Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors

  Bayburt, T. H. & Sligar, S. G., Jan 26 2021, U.S. Patent No. 10900971, Nov 16 2016

  Research output: Patent

• 2009

  Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4

  Frank, D. J., Denisov, I. G. & Sligar, S. G., Aug 15 2009, In: Archives of Biochemistry and Biophysics. 488, 2, p. 146-152 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  Functional assays of membrane-bound proteins with SAMDI-TOF mass spectrometry

  Marin, V. L., Bayburt, T. H., Sligar, S. G. & Mrksich, M., 2007, In: Angewandte Chemie - International Edition. 46, 46, p. 8796-8798 3 p.

  Research output: Contribution to journal › Article › peer-review
• 1998

  Changes in solvation during DNA binding and cleavage are critical to altered specificity of the EcoRI endonuclease

  Robinson, C. R. & Sligar, S. G., Mar 3 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 5, p. 2186-2191 6 p.

  Research output: Contribution to journal › Article › peer-review
• 1993

  Intramolecular Electron Transfer in Cytochrome b₅ Labeled with Ruthenium(II) Polypyridine Complexes: Rate Measurements in the Marcus Inverted Region

  Scott, J. R., Willie, A., McLean, M., Stayton, P. S., Sligar, S. G., Durham, B. & Millett, F., Jul 1 1993, In: Journal of the American Chemical Society. 115, 15, p. 6820-6824 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2001

  Oxygen-binding heme proteins incorporating circularly-permuted globins

  Sanders, K. & Sligar, S. G., May 22 2001, U.S. Patent No. 6235500, Jun 28 1999

  Research output: Patent

• 1988

  Determination of cytochrome b₅ association reactions. Characterization of metmyoglobin and cytochrome P-450(cam) binding to genetically engineered cytochrome

  Stayton, P. S., Fisher, M. T. & Sligar, S. G., 1988, In: Journal of Biological Chemistry. 263, 27, p. 13544-13548 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2021

  Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

  Cho, H., Gonzales-Wartz, K. K., Huang, D., Yuan, M., Peterson, M., Liang, J., Beutler, N., Torres, J. L., Cong, Y., Postnikova, E., Bangaru, S., Talana, C. A., Shi, W., Yang, E. S., Zhang, Y., Leung, K., Wang, L., Peng, L., Skinner, J., Li, S. & 20 others, Wu, N. C., Liu, H., Dacon, C., Moyer, T., Cohen, M., Zhao, M., Lee, F. E-H., Weinberg, R. S., Douagi, I., Gross, R., Schmaljohn, C., Pegu, A., Mascola, J. R., Holbrook, M., Nemazee, D., Rogers, T. F., Ward, A. B., Wilson, I. A., Crompton, P. D. & Tan, J., Apr 1 2021, (In preparation) (bioRxiv).

  Research output: Working paper
• 2018

  Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library

  Merkouris, S., Barde, Y. A., Binley, K. E., Allen, N. D., Stepanov, A. V., Wu, N. C., Grande, G., Lin, C. W., Li, M., Nan, X., Chacon-Fernandez, P., DiStefano, P. S., Lindsay, R. M., Lerner, R. A. & Xie, J., Jul 24 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 30, p. E7023-E7032

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design

  Du, Y., Xin, L., Shi, Y., Zhang, T. H., Wu, N. C., Dai, L., Gong, D., Brar, G., Shu, S., Luo, J., Reiley, W., Tseng, Y. W., Bai, H., Wu, T. T., Wang, J., Shu, Y. & Sun, R., Jan 19 2018, In: Science. 359, 6373, p. 290-296 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2014

  High-throughput profiling of point mutations across the HIV-1 genome

  Al-Mawsawi, L. Q., Wu, N. C., Olson, C. A., Shi, C. C., Qi, H., Zheng, X., Wu, T. T. & Sun, R., Dec 19 2014, In: Retrovirology. 11, 1, 124.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2016

  A benchmark study on error-correction by read-pairing and tag-clustering in amplicon-based deep sequencing

  Zhang, T. H., Wu, N. C. & Sun, R., Feb 12 2016, In: BMC genomics. 17, 1, 108.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2021

  Unlocking capacities of viral genomics for the COVID-19 pandemic response

  Knyazev, S., Chhugani, K., Ayyala, R., Singh, H., Karthikeyan, S., Deshpande, D., Comarova, Z., Lu, A., Sarwal, V., Porozov, Y., Wu, A., Abedalthagafi, M., Nagaraj, S., Smith, A., Skums, P., Ladner, J., Lam, T. T-Y., Wu, N., Zelikovsky, A., Knight, R. & 2 others, Crandall, K. & Mangul, S., Apr 28 2021, (E-pub ahead of print) (ArXiv).

  Research output: Working paper › Preprint

• 2017

  The intestinal copper exporter CUA-1 is required for systemic copper homeostasis in Caenorhabditis elegans

  Chun, H., Sharma, A. K., Lee, J., Chan, J., Jia, S. & Kim, B. E., Jan 6 2017, In: Journal of Biological Chemistry. 292, 1, p. 1-14 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Damage-Responsive Microcapsules for Amplified Photoacoustic Detection of Microcracks in Polymers

  Geng, J. L., Li, W., Smaga, L. P., Sottos, N. R. & Chan, J., Apr 10 2018, In: Chemistry of Materials. 30, 7, p. 2198-2202 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2017

  Host and pathogen copper-transporting P-type ATPases function antagonistically during Salmonella infection

  Ladomersky, E., Khan, A., Shanbhag, V., Cavet, J. S., Chan, J., Weisman, G. A. & Petris, M. J., Sep 1 2017, In: Infection and immunity. 85, 9, e00351-17.

  Research output: Contribution to journal › Article › peer-review
• 2018

  Photophysical Tuning of N-Oxide-Based Probes Enables Ratiometric Photoacoustic Imaging of Tumor Hypoxia

  Knox, H. J., Kim, T. W., Zhu, Z. & Chan, J., Jul 20 2018, In: ACS chemical biology. 13, 7, p. 1838-1843 6 p.

  Research output: Contribution to journal › Article › peer-review
• 2012

  Enzymology of influenza virus sialidase

  Chan, J. & Bennet, A. J., Jan 1 2012, Influenza Virus Sialidase - A Drug Discovery Target. Springer, p. 47-66 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2011

  Turnover Is rate-limited by deglycosylation for micromonospora viridifaciens sialidase-catalyzed hydrolyses: Conformational implications for the Michaelis complex

  Chan, J., Lu, A. & Bennet, A. J., Mar 9 2011, In: Journal of the American Chemical Society. 133, 9, p. 2989-2997 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2014

  Transition-state structure for the quintessential S_N2 reaction of a carbohydrate: Reaction of α-glucopyranosyl fluoride with azide ion in Water

  Chan, J. K. F., Sannikova, N., Tang, A. & Bennet, A. J., Sep 3 2014, In: Journal of the American Chemical Society. 136, 35, p. 12225-12228 4 p.

  Research output: Contribution to journal › Article › peer-review

• Transition-state structure for the hydronium-ion-promoted hydrolysis of ±- d -glucopyranosyl fluoride

  Chan, J. K. F., Tang, A. & Bennet, A. J., Jan 1 2014, In: Canadian Journal of Chemistry. 93, 4, p. 463-467 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2012

  Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase

  Macauley, M. S., Chan, J., Zandberg, W. F., He, Y., Whitworth, G. E., Stubbs, K. A., Yuzwa, S. A., Bennet, A. J., Varki, A., Davies, G. J. & Vocadlo, D. J., Aug 17 2012, In: Journal of Biological Chemistry. 287, 34, p. 28882-28897 16 p.

  Research output: Contribution to journal › Article › peer-review

• A stepwise solvent-promoted S _Ni reaction of α-d- glucopyranosyl fluoride: Mechanistic implications for retaining glycosyltransferases

  Chan, J., Tang, A. & Bennet, A. J., Jan 18 2012, In: Journal of the American Chemical Society. 134, 2, p. 1212-1220 9 p.

  Research output: Contribution to journal › Article › peer-review

• Bacterial and viral sialidases: Contribution of the conserved active site glutamate to catalysis

  Chan, J., Watson, J. N., Lu, A., Cerda, V. C., Borgford, T. J. & Bennet, A. J., Jan 10 2012, In: Biochemistry. 51, 1, p. 433-441 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2014

  Copper is an endogenous modulator of neural circuit spontaneous activity

  Dodani, S. C., Firl, A., Chan, J., Nam, C. I., Aron, A. T., Onak, C. S., Ramos-Torres, K. M., Paek, J., Webster, C. M., Feller, M. B. & Chang, C. J., Nov 18 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 46, p. 16280-16285 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2017

  A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

  Knox, H. J., Hedhli, J., Kim, T. W., Khalili, K., Dobrucki, L. W. & Chan, J., Dec 1 2017, In: Nature communications. 8, 1, 1794.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Development of Photoacoustic Probes for in Vivo Molecular Imaging

  Reinhardt, C. J. & Chan, J., Jan 16 2018, In: Biochemistry. 57, 2, p. 194-199 6 p.

  Research output: Contribution to journal › Review article › peer-review
• 2015

  Slow release of organoboronic acids in cross-coupling reactions

  Gillis, E. P., Burke, M. D. & Knapp, D. M., Apr 14 2015, U.S. Patent No. 9006463, Nov 6 2012

  Research output: Patent

• 2018

  Methods for forming protected organoboronic acids

  Gillis, E. P., Burke, M. D., Klubnick, J. A., Dick, G. R., Knapp, D. M. & Uno, B. E., Mar 6 2018, U.S. Patent No. 9908900, May 31 2016

  Research output: Patent

• 2011

  System for controlling the reactivity of boronic acids

  Lee, S. J., Gillis, E. P., Burke, M. D., Knapp, D. M. & Gray, K. C., Sep 6 2011, U.S. Patent No. 8013203, Nov 8 2007

  Research output: Patent

• 2006

  Redox enzymes in tethered membranes

  Jeuken, L. J. C., Connell, S. D., Henderson, P. J. F., Gennis, R. B., Evans, S. D. & Bushby, R. J., Feb 8 2006, In: Journal of the American Chemical Society. 128, 5, p. 1711-1716 6 p.

  Research output: Contribution to journal › Article › peer-review
• 1994

  The cytochrome oxidase superfamily of redox-driven proton pumps

  Calhoun, M. W., Thomas, J. W. & Gennis, R. B., Aug 1994, In: Trends in Biochemical Sciences. 19, 8, p. 325-330 6 p.

  Research output: Contribution to journal › Review article › peer-review
• 1996

  Two hydrophobic subunits are essential for the heme b ligation and functional assembly of complex II (succinate-ubiquinone oxidoreductase) from Escherichia coli

  Nakamura, K., Yamaki, M., Sarada, M., Nakayama, S., Vibat, C. R. T., Gennis, R. B., Nakayashiki, T., Inokuchi, H., Kojima, S. & Kita, K., Jan 5 1996, In: Journal of Biological Chemistry. 271, 1, p. 521-527 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2005

  Helix switching of a key active-site residue in the cytochrome cbb ₃ oxidases

  Hemp, J., Christian, C., Barquera, B., Gennis, R. B. & Martínez, T. J., Aug 16 2005, In: Biochemistry. 44, 32, p. 10766-10775 10 p.

  Research output: Contribution to journal › Article › peer-review
• 1980

  Phosphonate analogues of pyruvate. Probes of substrate binding to pyruvate oxidase and other thiamin pyrophosphate-dependent decarboxylases

  O'Brien, T. A., Kluger, R., Pike, D. C. & Gennis, R. B., May 14 1980, In: BBA - Enzymology. 613, 1, p. 10-17 8 p.

  Research output: Contribution to journal › Article › peer-review
• 1994

  Energy transduction by cytochrome complexes in mitochondrial and bacterial respiration: The enzymology of coupling electron transfer reactions to transmembrane proton translocation

  Trumpower, B. L. & Gennis, R. B., 1994, In: Annual review of biochemistry. 63, p. 675-716 42 p.

  Research output: Contribution to journal › Review article › peer-review
• 2013

  Single mutations that redirect internal proton transfer in the ba ₃ oxidase from thermus thermophilus

  Smirnova, I., Chang, H. Y., Von Ballmoos, C., Ädelroth, P., Gennis, R. B. & Brzezinski, P., Oct 8 2013, In: Biochemistry. 52, 40, p. 7022-7030 9 p.

  Research output: Contribution to journal › Article › peer-review
• 1994

  Deletion of the gene encoding cytochrome b₅₆₂ from Rhodobacter sphaeroides

  Yun, C. H., Barquera, B., Iba, K., Takamiya, K. I., Shapleigh, J., Crofts, A. R. & Gennis, R. B., Jul 1 1994, In: FEMS microbiology letters. 120, 1-2, p. 105-110 6 p.

  Research output: Contribution to journal › Article › peer-review
• 2018

  The electron distribution in the "activated" state of cytochrome c oxidase

  Vilhjálmsdóttir, J., Gennis, R. B. & Brzezinski, P., Dec 1 2018, In: Scientific reports. 8, 1, 7502.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2005

  Protein kinetics via spectroscopic imaging on a microfluidic chip

  Toepke, M. W., Brewer, S. H., Morgan, J. E., Vu, D. M., Ganesan, K., Rector, K. D., Woodruff, W. H., Gennis, R. B., Dyer, R. B. & Kenis, P. J. A., 2005, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. p. 12694 1 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2011

  Fault injection-based assessment of partial fault tolerance in stream processing applications

  Jacques-Silva, G., Gedik, B., Andrade, H., Wu, K. L. & Iyer, R. K., 2011, DEBS'11 - Proceedings of the 5th ACM International Conference on Distributed Event-Based Systems. p. 231-242 12 p. (DEBS'11 - Proceedings of the 5th ACM International Conference on Distributed Event-Based Systems).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2020

  Reproducibility of Voice Parameters: The Effect of Room Acoustics and Microphones

  Bottalico, P., Codino, J., Cantor-Cutiva, L. C., Marks, K., Nudelman, C. J., Skeffington, J., Shrivastav, R., Jackson-Menaldi, M. C., Hunter, E. J. & Rubin, A. D., May 2020, In: Journal of Voice. 34, 3, p. 320-334

  Research output: Contribution to journal › Article › peer-review
• 2022

  Telogator: A method for reporting chromosome-specific telomere lengths from long reads

  Stephens, Z., Ferrer, A., Boardman, L., Iyer, R. K. & Kocher, J. P. A., Apr 1 2022, In: Bioinformatics. 38, 7, p. 1788-1793 6 p.

  Research output: Contribution to journal › Article › peer-review
• 2018

  Characterizing Supercomputer Traffic Networks Through Link-Level Analysis

  Jha, S., Brandt, J., Gentile, A., Kalbarczyk, Z. & Iyer, R., Oct 29 2018, Proceedings - 2018 IEEE International Conference on Cluster Computing, CLUSTER 2018. Institute of Electrical and Electronics Engineers Inc., p. 562-570 9 p. 8514916. (Proceedings - IEEE International Conference on Cluster Computing, ICCC; vol. 2018-September).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Hands off the wheel in autonomous vehicles? A systems perspective on over a million miles of field data

  Banerjee, S. S., Jha, S., Cyriac, J., Kalbarczyk, Z. T. & Iyer, R. K., Jul 19 2018, Proceedings - 48th Annual IEEE/IFIP International Conference on Dependable Systems and Networks, DSN 2018. Institute of Electrical and Electronics Engineers Inc., p. 586-597 12 p. 8416518. (Proceedings - 48th Annual IEEE/IFIP International Conference on Dependable Systems and Networks, DSN 2018).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2008

  Reconfigurable Tamper-resistant Hardware Support Against Insider Threats: The Trusted ILLIAC Approach

  Iyer, R. K., Dabrowski, P., Nakka, N. & Kalbarczyk, Z., Jan 1 2008, Insider Attack and Cyber Security: Beyond the Hacker. Springer, p. 133-151 19 p. (Advances in Information Security; vol. 39).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2013

  Catalyst-controlled aliphatic c-h oxidations with a predictive model for site-selectivity

  Gormisky, P. E. & White, M. C., Sep 25 2013, In: Journal of the American Chemical Society. 135, 38, p. 14052-14055 4 p.

  Research output: Contribution to journal › Article › peer-review
• 2019

  Fundamentals of reliability analysis

  Hu, C., Youn, B. D. & Wang, P., 2019, Springer Series in Reliability Engineering. Springer, p. 83-100 18 p. (Springer Series in Reliability Engineering; vol. 0).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2007

  Processor-level selective replication

  Nakka, N., Pattabiraman, K. & Iyer, R., Nov 16 2007, Proceedings - 37th Annual IEEE/IFIP International Conference on Dependable Systems and Networks, DSN 2007. p. 544-553 10 p. 4273005. (Proceedings of the International Conference on Dependable Systems and Networks).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 1986

  USER-ORIENTED ANALYSIS OF FILE USAGE IN UNIX.

  Devarakonda, M. V. & Iyer, R. K., Dec 1 1986, Proceedings - IEEE Computer Society's International Computer Software & Applications Conference. IEEE, p. 21-27 7 p. (Proceedings - IEEE Computer Society's International Computer Software & Applications Conference).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution