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  • Yi Lu
2014

Fast screening of ligand-protein interactions based on ligand-induced protein stabilization of gold nanoparticles

New, S. Y., Aung, K. M. M., Lim, G. L., Hong, S., Tan, S. K., Lu, Y., Cheung, E. & Su, X., Mar 4 2014, In : Analytical chemistry. 86, 5, p. 2361-2370 10 p.

Research output: Contribution to journalArticle

2015

Nanomaterial-based biosensors using dual transducing elements for solution phase detection

Li, N., Su, X. & Lu, Y., May 7 2015, In : Analyst. 140, 9, p. 2916-2943 28 p.

Research output: Contribution to journalReview article

2014

Functional Nucleic Acid-Directed Assembly of Nanomaterials and Their Applications as Colorimetric and Fluorescent Sensors for Trace Contaminants in Water

Mazumdar, D., Liu, J. & Lu, Y., May 6 2014, Nanotechnology Applications for Clean Water: Solutions for Improving Water Quality: Second Edition. Elsevier Inc., p. 73-92 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Insights into the Competition between K+ and Pb2+ Binding to a G-Quadruplex and Discovery of a Novel K+-Pb2+-Quadruplex Intermediate

Yu, Z., Zhou, W., Ma, G., Li, Y., Fan, L., Li, X. & Lu, Y., Oct 11 2018, In : Journal of Physical Chemistry B. 122, 40, p. 9382-9388 7 p.

Research output: Contribution to journalArticle

2012

Label-free catalytic and molecular beacon containing an abasic site for sensitive fluorescent detection of small inorganic and organic molecules

Song, P., Xiang, Y., Xing, H., Zhou, Z., Tong, A. & Lu, Y., Mar 20 2012, In : Analytical chemistry. 84, 6, p. 2916-2922 7 p.

Research output: Contribution to journalArticle

2016

Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions

Hosseinzadeh, P., Mirts, E. N., Pfister, T. D., Gao, Y. G., Mayne, C., Robinson, H., Tajkhorshid, E. & Lu, Y., Mar 15 2016, In : Biochemistry. 55, 10, p. 1494-1502 9 p.

Research output: Contribution to journalArticle

Design of a single protein that spans the entire 2-V range of physiological redox potentials

Hosseinzadeh, P., Marshall, N. M., Chacón, K. N., Yu, Y., Nilges, M. J., New, S. Y., Tashkov, S. A., Blackburn, N. J. & Lu, Y., Jan 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 2, p. 262-267 6 p.

Research output: Contribution to journalArticle

2012

In vitro selection of metal Ion-Selective DNAzymes

Ihms, H. E. & Lu, Y., 2012, Ribozymes: Methods and Protocols. Hartig, J. (ed.). p. 297-316 20 p. (Methods in Molecular Biology; vol. 848).

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Direct EPR observation of a tyrosyl radical in a functional oxidase model in myoglobin during both H2O2 and O2 reactions

Yu, Y., Mukherjee, A., Nilges, M. J., Hosseinzadeh, P., Miner, K. D. & Lu, Y., Jan 29 2014, In : Journal of the American Chemical Society. 136, 4, p. 1174-1177 4 p.

Research output: Contribution to journalArticle

2017

Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids

Yu, Y., Cui, C., Wang, J. & Lu, Y., Feb 1 2017, In : Science China Chemistry. 60, 2, p. 188-200 13 p.

Research output: Contribution to journalReview article

2015

Long-range electron transfer in engineered azurins exhibits Marcus inverted region behavior

Farver, O., Hosseinzadeh, P., Marshall, N. M., Wherland, S., Lu, Y. & Pecht, I., Jan 2 2015, In : Journal of Physical Chemistry Letters. 6, 1, p. 100-105 6 p.

Research output: Contribution to journalArticle

Binuclear CuA Formation in Biosynthetic Models of CuA in Azurin Proceeds via a Novel Cu(Cys)2His Mononuclear Copper Intermediate

Chakraborty, S., Polen, M. J., Chacón, K. N., Wilson, T. D., Yu, Y., Reed, J., Nilges, M. J., Blackburn, N. J. & Lu, Y., Oct 6 2015, In : Biochemistry. 54, 39, p. 6071-6081 11 p.

Research output: Contribution to journalArticle

2011

Kinetics of copper incorporation into a biosynthetic purple Cu A azurin: Characterization of red, blue, and a new intermediate species

Wilson, T. D., Savelieff, M. G., Nilges, M. J., Marshall, N. M. & Lu, Y., Dec 28 2011, In : Journal of the American Chemical Society. 133, 51, p. 20778-20792 15 p.

Research output: Contribution to journalArticle

2013

PH-dependent evolution of five-star gold nanostructures: An experimental and computational study

Wang, Z., Bharathi, M. S., Hariharaputran, R., Xing, H., Tang, L., Li, J., Zhang, Y. W. & Lu, Y., Mar 26 2013, In : ACS Nano. 7, 3, p. 2258-2265 8 p.

Research output: Contribution to journalArticle

2012

Significant increase of oxidase activity through the genetic incorporation of a tyrosine-histidine cross-link in a myoglobin model of heme-copper oxidase

Liu, X., Yu, Y., Hu, C., Zhang, W., Lu, Y. & Wang, J., Apr 27 2012, In : Angewandte Chemie - International Edition. 51, 18, p. 4312-4316 5 p.

Research output: Contribution to journalArticle

2014

Redesigning the blue copper azurin into a redox-active mononuclear nonheme iron protein: Preparation and study of Fe(II)-M121E azurin

Liu, J., Meier, K. K., Tian, S., Zhang, J. L., Guo, H., Schulz, C. E., Robinson, H., Nilges, M. J., Münck, E. & Lu, Y., Sep 3 2014, In : Journal of the American Chemical Society. 136, 35, p. 12337-12344 8 p.

Research output: Contribution to journalArticle

2018
2013

A smart T1-weighted MRI contrast agent for uranyl cations based on a DNAzyme-gadolinium conjugate

Xu, W., Xing, H. & Lu, Y., Nov 7 2013, In : Analyst. 138, 21, p. 6266-6269 4 p.

Research output: Contribution to journalArticle

2014

Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterials

Wu, P., Yu, Y., McGhee, C. E., Tan, L. H. & Lu, Y., Dec 10 2014, In : Advanced Materials. 26, 46, p. 7849-7872 24 p.

Research output: Contribution to journalArticle

2017

Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand

Xing, H., Bai, Y., Bai, Y., Tan, L. H., Tao, J., Pedretti, B., Vincil, G. A., Lu, Y. & Zimmerman, S. C., Mar 15 2017, In : Journal of the American Chemical Society. 139, 10, p. 3623-3626 4 p.

Research output: Contribution to journalArticle

2011

A smart magnetic resonance imaging contrast agent responsive to adenosine based on a DNA aptamer-conjugated gadolinium complex

Xu, W. & Lu, Y., May 7 2011, In : Chemical Communications. 47, 17, p. 4998-5000 3 p.

Research output: Contribution to journalArticle

2016

Multimodal Detection of a Small Molecule Target Using Stimuli-Responsive Liposome Triggered by Aptamer-Enzyme Conjugate

Xing, H., Zhang, C. L., Ruan, G., Zhang, J., Hwang, K. & Lu, Y., Feb 2 2016, In : Analytical chemistry. 88, 3, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

Size-dependent modulation of graphene oxide-aptamer interactions for an amplified fluorescence-based detection of aflatoxin B1 with a tunable dynamic range

Zhang, J., Li, Z., Zhao, S. & Lu, Y., Jul 7 2016, In : Analyst. 141, 13, p. 4029-4034 6 p.

Research output: Contribution to journalArticle

2014

DNA aptamer technology for personalized medicine

Xing, H., Hwang, K., Li, J., Torabi, S. F. & Lu, Y., May 2014, In : Current Opinion in Chemical Engineering. 4, p. 79-87 9 p.

Research output: Contribution to journalReview article

2012

Biomimetic surface engineering of lanthanide-doped upconversion nanoparticles as versatile bioprobes

Li, L. L., Zhang, R., Yin, L., Zheng, K., Qin, W., Selvin, P. R. & Lu, Y., Jun 18 2012, In : Angewandte Chemie - International Edition. 51, 25, p. 6121-6125 5 p.

Research output: Contribution to journalArticle

2015

A biosynthetic model of cytochrome c oxidase as an electrocatalyst for oxygen reduction

Mukherjee, S., Mukherjee, A., Bhagi-Damodaran, A., Mukherjee, M., Lu, Y. & Dey, A., Oct 12 2015, In : Nature communications. 6, 8467.

Research output: Contribution to journalArticle

Recent Advances in Biosynthetic Modeling of Nitric Oxide Reductases and Insights Gained from Nuclear Resonance Vibrational and Other Spectroscopic Studies

Chakraborty, S., Reed, J., Sage, J. T., Branagan, N. C., Petrik, I. D., Miner, K. D., Hu, M. Y., Zhao, J., Alp, E. E. & Lu, Y., Aug 14 2015, In : Inorganic Chemistry. 54, 19, p. 9317-9329 13 p.

Research output: Contribution to journalArticle

2013

Metal ion as both a cofactor and a probe of metal-binding sites in a uranyl-specific DNAzyme: A uranyl photocleavage study

Cepeda-Plaza, M., Null, E. L. & Lu, Y., Nov 2013, In : Nucleic acids research. 41, 20, p. 9361-9370 10 p.

Research output: Contribution to journalArticle

2016

Design and engineering of artificial oxygen-activating metalloenzymes

Nastri, F., Chino, M., Maglio, O., Bhagi-Damodaran, A., Lu, Y. & Lombardi, A., Sep 21 2016, In : Chemical Society Reviews. 45, 18, p. 5020-5054 35 p.

Research output: Contribution to journalReview article

2017

Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme–Catalytic Hairpin Assembly Probe

Wu, Z., Fan, H., Satyavolu, N. S. R., Wang, W. J., Lake, R., Jiang, J. H. & Lu, Y., Jul 17 2017, In : Angewandte Chemie - International Edition. 56, 30, p. 8721-8725 5 p.

Research output: Contribution to journalArticle

2020

Precision-Guided Missile-Like DNA Nanostructure Containing Warhead and Guidance Control for Aptamer-Based Targeted Drug Delivery into Cancer Cells in Vitro and in Vivo

Ouyang, C., Zhang, S., Xue, C., Yu, X., Xu, H., Wang, Z., Lu, Y. & Wu, Z. S., Jan 22 2020, In : Journal of the American Chemical Society. 142, 3, p. 1265-1277 13 p.

Research output: Contribution to journalArticle

2013

A DNAzyme-gold nanoparticle probe for uranyl ion in living cells

Wu, P., Hwang, K., Lan, T. & Lu, Y., Apr 10 2013, In : Journal of the American Chemical Society. 135, 14, p. 5254-5257 4 p.

Research output: Contribution to journalArticle

2018

Evidence of a General Acid-Base Catalysis Mechanism in the 8-17 DNAzyme

Cepeda-Plaza, M., McGhee, C. E. & Lu, Y., Mar 6 2018, In : Biochemistry. 57, 9, p. 1517-1522 6 p.

Research output: Contribution to journalArticle

2016

A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site

Hosseinzadeh, P., Tian, S., Marshall, N. M., Hemp, J., Mullen, T., Nilges, M. J., Gao, Y. G., Robinson, H., Stahl, D. A., Gennis, R. B. & Lu, Y., May 25 2016, In : Journal of the American Chemical Society. 138, 20, p. 6324-6327 4 p.

Research output: Contribution to journalArticle

2014

Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers

Liu, X., Jiang, L., Li, J., Wang, L., Yu, Y., Zhou, Q., Lv, X., Gong, W., Lu, Y. & Wang, J., Sep 24 2014, In : Journal of the American Chemical Society. 136, 38, p. 13094-13097 4 p.

Research output: Contribution to journalArticle

Copper-sulfenate complex from oxidation of a cavity mutant of pseudomonas aeruginosa azurin

Sieracki, N. A., Tian, S., Hadt, R. G., Zhang, J. L., Woertink, J. S., Nilges, M. J., Sun, F., Solomon, E. I. & Lu, Y., Jan 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 924-929 6 p.

Research output: Contribution to journalArticle

2011
2014

Simple and efficient method to purify DNA-protein conjugates and its sensing applications

Zhou, Z., Xiang, Y., Tong, A. & Lu, Y., Apr 15 2014, In : Analytical chemistry. 86, 8, p. 3869-3875 7 p.

Research output: Contribution to journalArticle

2016

A density functional theory protocol for the calculation of redox potentials of copper complexes

Yan, L., Lu, Y. & Li, X., 2016, In : Physical Chemistry Chemical Physics. 18, 7, p. 5529-5536 8 p.

Research output: Contribution to journalArticle

Reversible S-nitrosylation in an engineered azurin

Tian, S., Liu, J., Cowley, R. E., Hosseinzadeh, P., Marshall, N. M., Yu, Y., Robinson, H., Nilges, M. J., Blackburn, N. J., Solomon, E. I. & Lu, Y., Jul 1 2016, In : Nature Chemistry. 8, 7, p. 670-677 8 p.

Research output: Contribution to journalArticle

2014

Correlating nuclear frequencies by two-dimensional ELDOR-detected NMR spectroscopy

Kaminker, I., Wilson, T. D., Savelieff, M. G., Hovav, Y., Zimmermann, H., Lu, Y. & Goldfarb, D., Mar 1 2014, In : Journal of Magnetic Resonance. 240, p. 77-89 13 p.

Research output: Contribution to journalArticle

2015

DNA-Encoded Tuning of Geometric and Plasmonic Properties of Nanoparticles Growing from Gold Nanorod Seeds

Song, T., Tang, L., Tan, L. H., Wang, X., Satyavolu, N. S. R., Xing, H., Wang, Z., Li, J., Liang, H. & Lu, Y., Jul 1 2015, In : Angewandte Chemie - International Edition. 54, 28, p. 8114-8118 5 p.

Research output: Contribution to journalArticle

In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing

Torabi, S. F., Wu, P., McGhee, C. E., Chen, L., Hwang, K., Zheng, N., Cheng, J. & Lu, Y., May 12 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 19, p. 5903-5908 6 p.

Research output: Contribution to journalArticle

2018

Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles

Yang, Z., Loh, K. Y., Chu, Y. T., Feng, R., Satyavolu, N. S. R., Xiong, M., Nakamata Huynh, S. M., Hwang, K., Li, L., Xing, H., Zhang, X., Chemla, Y. R., Gruebele, M. & Lu, Y., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17656-17665 10 p.

Research output: Contribution to journalArticle

2013

Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo

Xing, H., Tang, L., Yang, X., Hwang, K., Wang, W., Yin, Q., Wong, N. Y., Dobrucki, L. W., Yasui, N., Katzenellenbogen, J. A., Helferich, W. G., Cheng, J. & Lu, Y., Oct 21 2013, In : Journal of Materials Chemistry B. 1, 39, p. 5288-5297 10 p.

Research output: Contribution to journalArticle

2014

Uranium extraction: Coordination chemistry in the ocean

Lu, Y., Mar 1 2014, In : Nature Chemistry. 6, 3, p. 175-176 2 p.

Research output: Contribution to journalComment/debate

2020

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

Xiong, Y., Zhang, J., Yang, Z., Mou, Q., Ma, Y., Xiong, Y. & Lu, Y., Jan 8 2020, In : Journal of the American Chemical Society. 142, 1, p. 207-213 7 p.

Research output: Contribution to journalArticle

A photo-regulated aptamer sensor for spatiotemporally controlled monitoring of ATP in the mitochondria of living cells

Hong, S., Zhang, X., Lake, R. J., Pawel, G. T., Guo, Z., Pei, R. & Lu, Y., Jan 1 2020, In : Chemical Science. 11, 3, p. 713-720 8 p.

Research output: Contribution to journalArticle

Open Access
2016

DNA-Mediated Morphological Control of Pd-Au Bimetallic Nanoparticles

Satyavolu, N. S. R., Tan, L. H. & Lu, Y., Dec 21 2016, In : Journal of the American Chemical Society. 138, 50, p. 16542-16548 7 p.

Research output: Contribution to journalArticle