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  • Yi Lu
2018

Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase

Bhagi-Damodaran, A., Reed, J. H., Zhu, Q., Shi, Y., Hosseinzadeh, P., Sandoval, B. A., Harnden, K. A., Wang, S., Sponholtz, M. R., Mirts, E. N., Dwaraknath, S., Zhang, Y., Moënne-Loccoz, P. & Lu, Y., Jun 12 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 24, p. 6195-6200 6 p.

Research output: Contribution to journalArticle

2011

Spectroscopic characterization of mononitrosyl complexes in heme-nonheme diiron centers within the myoglobin scaffold (FeBMbs): Relevance to denitrifying No reductase

Hayashi, T., Miner, K. D., Yeung, N., Lin, Y. W., Lu, Y. & Moënne-Loccoz, P., Jul 5 2011, In : Biochemistry. 50, 26, p. 5939-5947 9 p.

Research output: Contribution to journalArticle

2012

DNA-directed assembly of asymmetric nanoclusters using Janus nanoparticles

Xing, H., Wang, Z., Xu, Z., Wong, N. Y., Xiang, Y., Liu, G. L. & Lu, Y., Jan 24 2012, In : ACS Nano. 6, 1, p. 802-809 8 p.

Research output: Contribution to journalArticle

2014

Functional DNA nanomaterials for sensing and imaging in living cells

Torabi, S. F. & Lu, Y., Aug 1 2014, In : Current Opinion in Biotechnology. 28, p. 88-95 8 p.

Research output: Contribution to journalReview article

2013
2019

Enzyme-Mediated Endogenous and Bioorthogonal Control of a DNAzyme Fluorescent Sensor for Imaging Metal Ions in Living Cells

Lin, Y., Yang, Z., Lake, R. J., Zheng, C. & Lu, Y., Nov 18 2019, In : Angewandte Chemie - International Edition. 58, 47, p. 17061-17067 7 p.

Research output: Contribution to journalArticle

2015

Using a Personal Glucose Meter and Alkaline Phosphatase for Point-of-Care Quantification of Galactose-1-Phosphate Uridyltransferase in Clinical Galactosemia Diagnosis

Zhang, J., Xiang, Y., Novak, D. E., Hoganson, G. E., Zhu, J. & Lu, Y., Oct 1 2015, In : Chemistry - An Asian Journal. 10, 10, p. 2221-2227 7 p.

Research output: Contribution to journalArticle

2016

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

Zhang, J. J., Cheng, F. F., Li, J. J., Zhu, J. J. & Lu, Y., Jun 1 2016, In : Nano Today. 11, 3, p. 309-329 21 p.

Research output: Contribution to journalReview article

2012

Spectroscopic and DFT studies of second-sphere variants of the type 1 copper site in azurin: Covalent and nonlocal electrostatic contributions to reduction potentials

Hadt, R. G., Sun, N., Marshall, N. M., Hodgson, K. O., Hedman, B., Lu, Y. & Solomon, E. I., Oct 10 2012, In : Journal of the American Chemical Society. 134, 40, p. 16701-16716 16 p.

Research output: Contribution to journalArticle

Polyvalent mesoporous silica nanoparticle-aptamer bioconjugates target breast cancer cells

Li, L. L., Yin, Q., Cheng, J. & Lu, Y., Sep 2012, In : Advanced Healthcare Materials. 1, 5, p. 567-572 6 p.

Research output: Contribution to journalArticle

2014

Identifying the elusive sites of tyrosyl radicals in cytochrome c peroxidase: Implications for oxidation of substrates bound at a site remote from the heme

Miner, K. D., Pfister, T. D., Hosseinzadeh, P., Karaduman, N., Donald, L. J., Loewen, P. C., Lu, Y. & Ivancich, A., Jun 17 2014, In : Biochemistry. 53, 23, p. 3781-3789 9 p.

Research output: Contribution to journalArticle

2013
2018

Nitric Oxide Reductase Activity in Heme-Nonheme Binuclear Engineered Myoglobins through a One-Electron Reduction Cycle

Sabuncu, S., Reed, J. H., Lu, Y. & Moënne-Loccoz, P., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17389-17393 5 p.

Research output: Contribution to journalArticle

2015

Mechanistic Insight into DNA-Guided Control of Nanoparticle Morphologies

Tan, L. H., Yue, Y., Satyavolu, N. S. R., Ali, A. S., Wang, Z., Wu, Y. & Lu, Y., Oct 22 2015, In : Journal of the American Chemical Society. 137, 45, p. 14456-14464 9 p.

Research output: Contribution to journalArticle

2014

Simple and efficient method to purify DNA-protein conjugates and its sensing applications

Zhou, Z., Xiang, Y., Tong, A. & Lu, Y., Apr 15 2014, In : Analytical chemistry. 86, 8, p. 3869-3875 7 p.

Research output: Contribution to journalArticle

2019

Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications

Zhang, J. J., Lan, T. & Lu, Y., Mar 21 2019, In : Advanced Healthcare Materials. 8, 6, 1801158.

Research output: Contribution to journalReview article

2015

Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid

Yu, Y., Zhou, Q., Wang, L., Liu, X., Zhang, W., Hu, M., Dong, J., Li, J., Lv, X., Ouyang, H., Li, H., Gao, F., Gong, W., Lu, Y. & Wang, J., Jul 1 2015, In : Chemical Science. 6, 7, p. 3881-3885 5 p.

Research output: Contribution to journalArticle

2012

Redox tuning of two biological copper centers through non-covalent interactions: Same trend but different magnitude

New, S. Y., Marshall, N. M., Hor, T. S. A., Xue, F. & Lu, Y., Apr 2 2012, In : Chemical Communications. 48, 35, p. 4217-4219 3 p.

Research output: Contribution to journalArticle

2014

The production of nitrous oxide by the heme/nonheme diiron center of engineered myoglobins (FeBMbs) proceeds through a trans -iron-nitrosyl dimer

Matsumura, H., Hayashi, T., Chakraborty, S., Lu, Y. & Moënne-Loccoz, P., Feb 12 2014, In : Journal of the American Chemical Society. 136, 6, p. 2420-2431 12 p.

Research output: Contribution to journalArticle

Spectroscopic and computational study of a nonheme iron nitrosyl center in a biosynthetic model of nitric oxide reductase

Chakraborty, S., Reed, J., Ross, M., Nilges, M. J., Petrik, I. D., Ghosh, S., Hammes-Schiffer, S., Sage, J. T., Zhang, Y., Schulz, C. E. & Lu, Y., Feb 24 2014, In : Angewandte Chemie - International Edition. 53, 9, p. 2417-2421 5 p.

Research output: Contribution to journalArticle

2017

Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase

Bhagi-Damodaran, A., Kahle, M., Shi, Y., Zhang, Y., Ädelroth, P. & Lu, Y., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 23, p. 6622-6626 5 p.

Research output: Contribution to journalArticle

2012

A designed functional metalloenzyme that reduces O 2 to H 2O with over one thousand turnovers

Miner, K. D., Mukherjee, A., Gao, Y. G., Null, E. L., Petrik, I. D., Zhao, X., Yeung, N., Robinson, H. & Lu, Y., Jun 4 2012, In : Angewandte Chemie - International Edition. 51, 23, p. 5589-5592 4 p.

Research output: Contribution to journalArticle

2016

Design of Heteronuclear Metalloenzymes

Bhagi-Damodaran, A., Hosseinzadeh, P., Mirts, E., Reed, J., Petrik, I. D. & Lu, Y., 2016, Methods in Enzymology. Academic Press Inc., p. 501-537 37 p. (Methods in Enzymology; vol. 580).

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

The importance of peripheral sequences in determining the metal selectivity of an in vitro-selected co 2+-Dependent DNAzyme

Nelson, K. E., Ihms, H. E., Mazumdar, D., Bruesehoff, P. J. & Lu, Y., Feb 13 2012, In : ChemBioChem. 13, 3, p. 381-391 11 p.

Research output: Contribution to journalArticle

Discovery of the DNA "genetic code" for abiological gold nanoparticle morphologies

Wang, Z., Tang, L., Tan, L. H., Li, J. & Lu, Y., Sep 3 2012, In : Angewandte Chemie - International Edition. 51, 36, p. 9078-9082 5 p.

Research output: Contribution to journalArticle

2014

DNazyme-functionalized gold nanoparticles for biosensing

Xiang, Y., Wu, P., Tan, L. H. & Lu, Y., 2014, In : Advances in Biochemical Engineering/Biotechnology. 140, p. 93-120 28 p.

Research output: Contribution to journalArticle

2015

DNA-Encoded Tuning of Geometric and Plasmonic Properties of Nanoparticles Growing from Gold Nanorod Seeds

Song, T., Tang, L., Tan, L. H., Wang, X., Satyavolu, N. S. R., Xing, H., Wang, Z., Li, J., Liang, H. & Lu, Y., Jul 1 2015, In : Angewandte Chemie - International Edition. 54, 28, p. 8114-8118 5 p.

Research output: Contribution to journalArticle

2017

Thiolate Spin Population of Type I Copper in Azurin Derived from33S Hyperfine Coupling

Ramirez Cohen, M., Mendelman, N., Radoul, M., Wilson, T. D., Savelieff, M. G., Zimmermann, H., Kaminker, I., Feintuch, A., Lu, Y. & Goldfarb, D., Jun 5 2017, In : Inorganic Chemistry. 56, 11, p. 6163-6174 12 p.

Research output: Contribution to journalArticle

2020

Structural Basis for a Quadratic Relationship between Electronic Absorption and Electronic Paramagnetic Resonance Parameters of Type 1 Copper Proteins

Yu, S. S., Li, J. J., Cui, C., Tian, S., Chen, J. J., Yu, H. Q., Hou, C., Nilges, M. J. & Lu, Y., 2020, (Accepted/In press) In : Inorganic Chemistry.

Research output: Contribution to journalArticle

2011

Small-molecule diagnostics based on functional DNA nanotechnology: A dipstick test for mercury

Torabi, S. F. & Lu, Y., 2011, In : Faraday Discussions. 149, p. 125-135 11 p.

Research output: Contribution to journalArticle

2012

Vibrational dynamics of oxygenated heme proteins

Zeng, W., Barabanschikov, A., Wang, N., Lu, Y., Zhao, J., Sturhahn, W., Alp, E. E. & Sage, J. T., May 30 2012, In : Chemical Communications. 48, 51, p. 6340-6342 3 p.

Research output: Contribution to journalArticle

2011

The important role of covalent anchor positions in tuning catalytic properties of a rationally designed Mnsalen-containing metalloenzyme

Garner, D. K., Liang, L., Barrios, D. A., Zhang, J. L. & Lu, Y., Sep 2 2011, In : ACS Catalysis. 1, 9, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

2013

A dual-emission fluorescent nanocomplex of gold-cluster-decorated silica particles for live cell imaging of highly reactive oxygen species

Chen, T., Hu, Y., Cen, Y., Chu, X. & Lu, Y., Aug 7 2013, In : Journal of the American Chemical Society. 135, 31, p. 11595-11602 8 p.

Research output: Contribution to journalArticle

2019

Functional Nucleic Acid Nanomaterials: Development, Properties, and Applications

Xu, W., He, W., Du, Z., Zhu, L., Huang, K., Lu, Y. & Luo, Y., 2019, (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Contribution to journalReview article

Bioapplications of DNA nanotechnology at the solid-liquid interface

Wang, W., Yu, S., Huang, S., Bi, S., Han, H., Zhang, J. R., Lu, Y. & Zhu, J. J., Sep 21 2019, In : Chemical Society Reviews. 48, 18, p. 4892-4920 29 p.

Research output: Contribution to journalReview article

2015

Jun-Long Zhang

Zhang, J. L., Che, C. M. & Lu, Y., Jan 2015, In : ChemPlusChem. 80, 1, p. 25 1 p.

Research output: Contribution to journalComment/debate

2017

“Dipstick” colorimetric detection of metal ions based on immobilization of DNAzyme and gold nanoparticles onto a lateral flow device

Mazumdar, D., Lan, T. & Lu, Y., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 389-406 18 p. (Methods in Molecular Biology; vol. 1571).

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Using aptamers to elucidate esophageal cancer clinical samples

Liu, Z., Lu, Y., Pu, Y., Liu, J., Liu, B., Yu, B., Chen, K., Fu, T., Yang, C. J., Liu, H. & Tan, W., Dec 21 2015, In : Scientific reports. 5, 18516.

Research output: Contribution to journalArticle

2016

Integration of Solution-Based Assays onto Lateral Flow Device for One-Step Quantitative Point-of-Care Diagnostics Using Personal Glucose Meter

Zhang, J., Shen, Z., Xiang, Y. & Lu, Y., Sep 23 2016, In : ACS Sensors. 1, 9, p. 1091-1096 6 p.

Research output: Contribution to journalArticle

2020

Independent control over size, valence, and elemental composition in the synthesis of DNA-nanoparticle conjugates

Bai, Y., Xing, H., Bai, Y., Tan, L. H., Hwang, K., Li, J., Lu, Y. & Zimmerman, S. C., Feb 14 2020, In : Chemical Science. 11, 6, p. 1564-1572 9 p.

Research output: Contribution to journalArticle

Open Access
2019

Discovery of and Insights into DNA “Codes” for Tunable Morphologies of Metal Nanoparticles

Satyavolu, N. S. R., Loh, K. Y., Tan, L. H. & Lu, Y., Jun 26 2019, In : Small. 15, 26, 1900975.

Research output: Contribution to journalReview article

2014

Photocaged DNAzymes as a general method for sensing metal ions in living cells

Hwang, K., Wu, P., Kim, T., Lei, L., Tian, S., Wang, Y. & Lu, Y., Oct 14 2014, In : Angewandte Chemie - International Edition. 53, 50, p. 13798-13802 5 p.

Research output: Contribution to journalArticle

2013

Facile and efficient preparation of anisotropic DNA-functionalized gold nanoparticles and their regioselective assembly

Tan, L. H., Xing, H., Chen, H. & Lu, Y., Nov 27 2013, In : Journal of the American Chemical Society. 135, 47, p. 17675-17678 4 p.

Research output: Contribution to journalArticle

2019

DNAzymes as Activity-Based Sensors for Metal Ions: Recent Applications, Demonstrated Advantages, Current Challenges, and Future Directions

Lake, R. J., Yang, Z., Zhang, J. J. & Lu, Y., Dec 17 2019, In : Accounts of chemical research. 52, 12, p. 3275-3286 12 p.

Research output: Contribution to journalArticle

Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter

Xu, J., Qiao, X., Zhang, J., Cheng, N., Sheng, Q., Zheng, J., Cao, W., Yue, T. & Lu, Y., Apr 14 2019, In : Analytical Methods. 11, 14, p. 1849-1856 8 p.

Research output: Contribution to journalArticle

2018

DNA-encoded morphological evolution of bimetallic Pd@Au core-shell nanoparticles from a high-indexed core

Satyavolu, N. S. R., Pishevaresfahani, N., Tan, L. H. & Lu, Y., Sep 1 2018, In : Nano Research. 11, 9, p. 4549-4561 13 p.

Research output: Contribution to journalArticle

2015

Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

Yu, Y., Lv, X., Li, J., Zhou, Q., Cui, C., Hosseinzadeh, P., Mukherjee, A., Nilges, M. J., Wang, J. & Lu, Y., Apr 15 2015, In : Journal of the American Chemical Society. 137, 14, p. 4594-4597 4 p.

Research output: Contribution to journalArticle

Chemical Control over Cellular Uptake of Organic Nanoparticles by Fine Tuning Surface Functional Groups

Bai, Y., Xing, H., Wu, P., Feng, X., Hwang, K., Lee, J. M., Phang, X. Y., Lu, Y. & Zimmerman, S. C., Sep 1 2015, In : ACS Nano. 9, 10, p. 10227-10236 10 p.

Research output: Contribution to journalArticle

2012

Direct detection of adenosine in undiluted serum using a luminescent aptamer sensor attached to a terbium complex

Li, L. L., Ge, P., Selvin, P. R. & Lu, Y., Sep 18 2012, In : Analytical chemistry. 84, 18, p. 7852-7856 5 p.

Research output: Contribution to journalArticle