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2016

The CO Photodissociation and Recombination Dynamics of the W172Y/F282T Ligand Channel Mutant of Rhodobacter sphaeroides aa3 Cytochrome c Oxidase

Cassano, J. A., Choi, S. K., McDonald, W., Szundi, I., Villa Gawboy, T. R., Gennis, R. B. & Einarsdóttir, Ó., May 1 2016, In : Photochemistry and Photobiology. 92, 3, p. 410-419 10 p.

Research output: Contribution to journalArticle

Photodissociation
Rhodobacter sphaeroides
oxidase
cytochromes
Electron Transport Complex IV
2010

Partial steps of charge translocation in the nonpumping N139l mutant of rhodobacter sphaeroides cytochrome c oxidase with a blocked d-channel

Siletsky, S. A., Zhu, J., Gennis, R. B. & Konstantinov, A. A., Apr 13 2010, In : Biochemistry. 49, 14, p. 3060-3073 14 p.

Research output: Contribution to journalArticle

Rhodobacter sphaeroides
Electron Transport Complex IV
Protons
Enzymes
Oxidoreductases
2011

2D-SEIRA spectroscopy to highlight conformational changes of the cytochrome c oxidase induced by direct electron transfer

Nowak, C., Laredo, T., Gebert, J., Lipkowski, J., Gennis, R. B., Ferguson-Miller, S., Knoll, W. & Naumann, R. L. C., Jun 1 2011, In : Metallomics. 3, 6, p. 619-627 9 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Spectrum Analysis
Spectroscopy
Electrons
Biomimetics
2016
Thermus thermophilus
Lipid bilayers
Lipid Bilayers
Catalytic Domain
Tunnels
2012
Rhodobacter capsulatus
Rhodobacter sphaeroides
Bacterial Proteins
Electron Transport Complex IV
Protons
Rhodobacter sphaeroides
Electron Transport Complex IV
Cytochromes c
Horses
His-His-His-His-His-His
2013

Solid-state NMR study of a 41 kDa membrane protein complex DsbA/DsbB

Sperling, L. J., Tang, M., Berthold, D. A., Nesbitt, A. E., Gennis, R. B. & Rienstra, C. M., May 23 2013, In : Journal of Physical Chemistry B. 117, 20, p. 6052-6060 9 p.

Research output: Contribution to journalArticle

Chemical shift
chemical equilibrium
Catalytic Domain
Membrane Proteins
Nuclear magnetic resonance
2011

Entrance of the proton pathway in cbb 3-type heme-copper oxidases

Lee, H. J., Gennis, R. B. & Ädelroth, P., Oct 25 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17661-17666 6 p.

Research output: Contribution to journalArticle

Heme
Protons
Rhodobacter sphaeroides
Proton-Motive Force
Membranes
2013

Characterization of the nitric oxide reductase from Thermus thermophilus

Schurig-Briccio, L. A., Venkatakrishnan, P., Hemp, J., Bricio, C., Berenguer, J. & Gennis, R. B., Jul 30 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 31, p. 12613-12618 6 p.

Research output: Contribution to journalArticle

Thermus thermophilus
Heme
Catalytic Domain
Oxidoreductases
Enzymes
2015

The two transmembrane helices of CcoP are sufficient for assembly of the cbb3-type heme-copper oxygen reductase from Vibrio cholerae

Ahn, Y. O., Lee, H. J., Kaluka, D., Yeh, S. R., Rousseau, D. L., Ädelroth, P. & Gennis, R. B., Jul 13 2015, In : Biochimica et Biophysica Acta - Bioenergetics. 1847, 10, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Heme
Copper
Oxidoreductases
Oxygen
2018
Oxidoreductases
Nitric Oxide
Substrates
Catalytic Domain
Tunnels
2013

Direct electrochemistry of cytochrome bo3 oxidase at a series of gold nanoparticles-modified electrodes

Melin, F., Meyer, T., Lankiang, S., Choi, S. K., Gennis, R. B., Blanck, C., Schmutz, M. & Hellwig, P., Jan 1 2013, In : Electrochemistry Communications. 26, 1, p. 105-108 4 p.

Research output: Contribution to journalArticle

Electrochemistry
Gold
Nanoparticles
Proteins
Immobilized Enzymes
2010

A positive feedback-based gene circuit to increase the production of a membrane protein

Bansal, K., Yang, K., Nistala, G. J., Gennis, R. B. & Bhalerao, K. D., May 25 2010, In : Journal of Biological Engineering. 4, 6.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Membrane Proteins
Genes
Proteins
Membranes
2013

Proton uptake and pKa changes in the uncoupled Asn139Cys variant of cytochrome c oxidase

Johansson, A. L., Carlsson, J., Högbom, M., Hosler, J. P., Gennis, R. B. & Brzezinski, P., Feb 5 2013, In : Biochemistry. 52, 5, p. 827-836 10 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Protons
Membrane Proteins
Membranes
Proton Pumps
2012

Functional importance of a pair of conserved glutamic acid residues and of Ca2+ binding in the cbb 3-type oxygen reductases from rhodobacter sphaeroides and vibrio cholerae

Ouyang, H., Han, H., Roh, J. H., Hemp, J., Hosler, J. P. & Gennis, R. B., Sep 18 2012, In : Biochemistry. 51, 37, p. 7290-7296 7 p.

Research output: Contribution to journalArticle

Rhodobacter sphaeroides
Vibrio cholerae
Heme
Glutamic Acid
Glutamates

Interactions of intermediate semiquinone with surrounding protein residues at the QH site of wild-type and D75H mutant cytochrome bo 3 from Escherichia coli

Lin, M. T., Baldansuren, A., Hart, R., Samoilova, R. I., Narasimhulu, K. V., Yap, L. L., Choi, S. K., O'Malley, P. J., Gennis, R. B. & Dikanov, S. A., May 8 2012, In : Biochemistry. 51, 18, p. 3827-3838 12 p.

Research output: Contribution to journalArticle

Cytochromes
Labeling
Escherichia coli
Nitrogen
Proteins
2015

Plasticity in the High Affinity Menaquinone Binding Site of the Cytochrome aa3-600 Menaquinol Oxidase from Bacillus subtilis

Yi, S. M., Taguchi, A. T., Samoilova, R. I., O'Malley, P. J., Gennis, R. B. & Dikanov, S. A., Jul 21 2015, In : Biochemistry. 54, 32, p. 5030-5044 15 p.

Research output: Contribution to journalArticle

Vitamin K 2
Electron Transport Complex IV
Bacilli
Bacillus subtilis
Plasticity
2010

Functional interactions between membrane-bound transporters and membranes

Öjemyr, L. N., Lee, H. J., Gennis, R. B. & Brzezinski, P., Sep 7 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 36, p. 15763-15767 5 p.

Research output: Contribution to journalArticle

Membrane Transport Proteins
Membranes
Protons
Membrane Proteins
Respiratory Transport
2018

Role of the tightly bound quinone for the oxygen reaction of cytochrome bo3 oxidase from Escherichia coli

Melin, F., Sabuncu, S., Choi, S. K., Leprince, A., Gennis, R. B. & Hellwig, P., Oct 2018, In : FEBS Letters. 592, 20, p. 3380-3387 8 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Escherichia coli
Oxygen
Quinones
Ubiquinone
2012

Characterization of the PIB-Type ATPases present in Thermus thermophilus

Schurig-Briccio, L. A. & Gennis, R. B., Aug 1 2012, In : Journal of bacteriology. 194, 15, p. 4107-4113 7 p.

Research output: Contribution to journalArticle

Thermus thermophilus
Adenosine Triphosphatases
Copper
Genes
Cadmium
2018

The electron distribution in the "activated" state of cytochrome c oxidase

Vilhjálmsdóttir, J., Gennis, R. B. & Brzezinski, P., Dec 1 2018, In : Scientific reports. 8, 1, 7502.

Research output: Contribution to journalArticle

Open Access
Electron Transport Complex IV
Electrons
Protons
Free energy
Membranes
2010

Characterization of the semiquinone radical stabilized by the cytochrome aa3-600 menaquinol oxidase of Bacillus subtilis

Yi, S. M., Narasimhulu, K. V., Samoilova, R. I., Gennis, R. B. & Dikanov, S. A., Jun 11 2010, In : Journal of Biological Chemistry. 285, 24, p. 18241-18251 11 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Bacilli
Cytochromes
Bacillus subtilis
Ubiquinone
2016

The unusual redox properties of C-type oxidases

Melin, F., Xie, H., Meyer, T., Ahn, Y. O., Gennis, R. B., Michel, H. & Hellwig, P., Dec 1 2016, In : Biochimica et Biophysica Acta - Bioenergetics. 1857, 12, p. 1892-1899 8 p.

Research output: Contribution to journalArticle

Heme
Oxidation-Reduction
Oxidoreductases
Protons
Pseudomonas stutzeri

A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site

Hosseinzadeh, P., Tian, S., Marshall, N. M., Hemp, J., Mullen, T., Nilges, M. J., Gao, Y. G., Robinson, H., Stahl, D. A., Gennis, R. B. & Lu, Y., May 25 2016, In : Journal of the American Chemical Society. 138, 20, p. 6324-6327 4 p.

Research output: Contribution to journalArticle

Binding sites
Copper
Binding Sites
electron spin resonance
copper
2019

Microcin J25 inhibits ubiquinol oxidase activity of purified cytochrome bd-I from Escherichia coli

Galván, A. E., Chalón, M. C., Ríos Colombo, N. S., Schurig-Briccio, L. A., Sosa-Padilla, B., Gennis, R. B. & Bellomio, A., May 2019, In : Biochimie. 160, p. 141-147 7 p.

Research output: Contribution to journalArticle

Cytochromes
Escherichia coli
Peptides
Cyanides
Electron Transport
2012

Exploring the proton pump and exit pathway for pumped protons in cytochrome ba 3 from Thermus thermophilus

Chang, H. Y., Choi, S. K., Vakkasoglu, A. S., Chen, Y., Hemp, J., Fee, J. A. & Gennis, R. B., Apr 3 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5259-5264 6 p.

Research output: Contribution to journalArticle

Thermus thermophilus
Proton Pumps
Propionates
Protons
Hydrogen
2013

Characterization of the Type III sulfide:quinone oxidoreductase from Caldivirga maquilingensis and its membrane binding

Lencina, A. M., Ding, Z., Schurig-Briccio, L. A. & Gennis, R. B., Mar 1 2013, In : Biochimica et Biophysica Acta - Bioenergetics. 1827, 3, p. 266-275 10 p.

Research output: Contribution to journalArticle

sulfide quinone reductase
Membranes
Sulfides
Enzymes
Electrons

Structure of the disulfide bond generating membrane protein DsbB in the lipid bilayer

Tang, M., Nesbitt, A. E., Sperling, L. J., Berthold, D. A., Schwieters, C. D., Gennis, R. B. & Rienstra, C. M., May 27 2013, In : Journal of Molecular Biology. 425, 10, p. 1670-1682 13 p.

Research output: Contribution to journalArticle

Lipid Bilayers
Molecular Dynamics Simulation
Disulfides
Membrane Proteins
X-Rays
2010
Rhodobacter sphaeroides
Electron Transport Complex IV
Heme
Electrons
Protons
2013

Alternate pathways for NADH oxidation in Thermus thermophilus using type 2 NADH dehydrogenases

Venkatakrishnan, P., Lencina, A. M., Schurig-Briccio, L. A. & Gennis, R. B., May 1 2013, In : Biological Chemistry. 394, 5, p. 667-676 10 p.

Research output: Contribution to journalArticle

Thermus thermophilus
NADH Dehydrogenase
NAD
Genes
Oxidation
2018

Mechanism of proton transfer through the KC proton pathway in the Vibrio cholerae cbb3 terminal oxidase

Ahn, Y. O., Albertsson, I., Gennis, R. B. & Ädelroth, P., Nov 2018, In : Biochimica et Biophysica Acta - Bioenergetics. 1859, 11, p. 1191-1198 8 p.

Research output: Contribution to journalArticle

Proton transfer
Vibrio cholerae
Protons
Oxidoreductases
Oxygen
2012

Cell-free synthesis of cytochrome bo 3 ubiquinol oxidase in artificial membranes

Yildiz, A. A., Knoll, W., Gennis, R. B. & Sinner, E. K., Apr 1 2012, In : Analytical Biochemistry. 423, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

Artificial Membranes
Cytochromes
Membranes
Membrane Proteins
Proteins
2010

Intricate role of water in proton transport through cytochrome c oxidase

Lee, H. J., Svahn, E., Swanson, J. M. J., Lepp, H., Voth, G. A., Brzezinski, P. & Gennis, R. B., Nov 17 2010, In : Journal of the American Chemical Society. 132, 45, p. 16225-16239 15 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
cytochrome
Protons
mutation
Water
2012

Structure changes upon deprotonation of the proton release group in the bacteriorhodopsin photocycle

Morgan, J. E., Vakkasoglu, A. S., Lanyi, J. K., Lugtenburg, J., Gennis, R. B. & Maeda, A., Aug 8 2012, In : Biophysical journal. 103, 3, p. 444-452 9 p.

Research output: Contribution to journalArticle

Bacteriorhodopsins
Protons
Water
Fourier Analysis
2019

Characterization and X-ray structure of the NADH-dependent coenzyme A disulfide reductase from Thermus thermophilus

Lencina, A. M., Koepke, J., Preu, J., Muenke, C., Gennis, R. B., Michel, H. & Schurig-Briccio, L. A., Nov 1 2019, In : Biochimica et Biophysica Acta - Bioenergetics. 1860, 11, 148080.

Research output: Contribution to journalArticle

Thermus thermophilus
Vitamin K 3
NAD
Oxidoreductases
X-Rays
2012

Timing of electron and proton transfer in the ba3 cytochrome c oxidase from Thermus thermophilus

Von Ballmoos, C., Lachmann, P., Gennis, R. B., Ädelroth, P. & Brzezinski, P., Jun 5 2012, In : Biochemistry. 51, 22, p. 4507-4517 11 p.

Research output: Contribution to journalArticle

Thermus thermophilus
Proton transfer
Electron Transport Complex IV
Protons
Electrons
2017

Dynamics of the KB Proton Pathway in Cytochrome ba3 from Thermus thermophilus

von Ballmoos, C., Smirnova, I., Poiana, F., Gonska, N., Chang, H. Y., Gennis, R. B., Brzezinski, P. & Ädelroth, P., May 1 2017, In : Israel Journal of Chemistry. 57, 5, p. 424-436 13 p.

Research output: Contribution to journalArticle

Protons
Oxidoreductases
Proton transfer
Pumps
Proton Pumps
2016

CtaM is required for menaquinol oxidase aa 3 function in Staphylococcus aureus

Hammer, N. D., Schurig-Briccio, L. A., Gerdes, S. Y., Gennis, R. B. & Skaar, E. P., Jul 1 2016, In : mBio. 7, 4, e00823-16.

Research output: Contribution to journalArticle

Staphylococcus aureus
Oxidoreductases
Electron Transport
Heme
Oxygen
2010

Conformational transitions and molecular hysteresis of cytochrome c oxidase: Varying the redox state by electronic wiring

Nowak, C., Santonicola, M. G., Schach, D., Zhu, J., Gennis, R. B., Ferguson-Miller, S., Baurecht, D., Walz, D., Knoll, W. & Naumann, R. L. C., Nov 7 2010, In : Soft Matter. 6, 21, p. 5523-5532 10 p.

Research output: Contribution to journalArticle

wiring
oxidase
cytochromes
Electron Transport Complex IV
Electric wiring
2013

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase

Johansson, A. L., Högbom, M., Carlsson, J., Gennis, R. B. & Brzezinski, P., May 28 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 22, p. 8912-8917 6 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Aspartic Acid
Protons
Biological Phenomena
Membranes
2017

X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization

Schieferstein, J. M., Pawate, A. S., Sun, C., Wan, F., Sheraden, P. N., Broecker, J., Ernst, O. P., Gennis, R. B. & Kenis, P. J. A., Mar 1 2017, In : Biomicrofluidics. 11, 2, 024118.

Research output: Contribution to journalArticle

Microfluidics
Crystallization
Screening
Membrane Proteins
screening
2015

Escherichia coli Auxotroph Host Strains for Amino Acid-Selective Isotope Labeling of Recombinant Proteins

Lin, M. T., Fukazawa, R., Miyajima-Nakano, Y., Matsushita, S., Choi, S. K., Iwasaki, T. & Gennis, R. B., Jan 1 2015, Methods in Enzymology. Academic Press Inc., p. 45-66 22 p. (Methods in Enzymology; vol. 565).

Research output: Chapter in Book/Report/Conference proceedingChapter

Isotope Labeling
Recombinant Proteins
Isotopes
Labeling
Escherichia coli
2010

Catalase activity of cytochrome c oxidase assayed with hydrogen peroxide-sensitive electrode microsensor

Bolshakov, I. A., Vygodina, T. V., Gennis, R. B., Karyakin, A. A. & Konstantinov, A. A., Nov 1 2010, In : Biochemistry (Moscow). 75, 11, p. 1352-1360 9 p.

Research output: Contribution to journalArticle

Microsensors
Electron Transport Complex IV
Catalase
Hydrogen Peroxide
Electrodes
2017

Location of the Substrate Binding Site of the Cytochrome bo3 Ubiquinol Oxidase from Escherichia coli

Choi, S. K., Schurig-Briccio, L., Ding, Z., Hong, S., Sun, C. & Gennis, R. B., Jun 21 2017, In : Journal of the American Chemical Society. 139, 24, p. 8346-8354 9 p.

Research output: Contribution to journalArticle

Binding sites
Cytochromes
Escherichia coli
cytochrome
coenzyme Q10
2010
Bacteriorhodopsins
Deprotonation
Proton transfer
Protons
Water
Rhodobacter sphaeroides
Electron Transport Complex IV
Protons
Hydrogen
Mutation
2011

Exploring by pulsed EPR the electronic structure of ubisemiquinone bound at the QH site of cytochrome bo3 from Escherichia coli with in vivo 13C-labeled methyl and methoxy substituents

Lin, M. T., Shubin, A. A., Samoilova, R. I., Narasimhulu, K. V., Baldansuren, A., Gennis, R. B. & Dikanov, S. A., Mar 25 2011, In : Journal of Biological Chemistry. 286, 12, p. 10105-10114 10 p.

Research output: Contribution to journalArticle

coenzyme Q10
Cytochromes
Escherichia coli
Electronic structure
Paramagnetic resonance
2010

The diheme cytochrome c 4 from Vibrio cholerae is a natural electron donor to the respiratory cbb 3 oxygen reductase

Chang, H. Y., Ahn, Y., Pace, L. A., Lin, M. T., Lin, Y. H. & Gennis, R. B., Sep 7 2010, In : Biochemistry. 49, 35, p. 7494-7503 10 p.

Research output: Contribution to journalArticle

Vibrio cholerae
Oxidoreductases
Electrons
Oxygen
Proteobacteria
2015

Review and Hypothesis. New insights into the reaction mechanism of transhydrogenase: Swivelling the dIII component may gate the proton channel

Jackson, J. B., Leung, J. H., Stout, C. D., Schurig-Briccio, L. A. & Gennis, R. B., Jul 20 2015, In : FEBS Letters. 589, 16, p. 2027-2033 7 p.

Research output: Contribution to journalReview article

NADP
Protons
Thermus thermophilus
Mitochondria
Enzymes