Find Research Outputs

Search results

• 2010

  Activation of ERα is necessary for estradiol's anorexigenic effect in female rats

  Santollo, J., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Eckel, L. A., Nov 2010, In: Hormones and Behavior. 58, 5, p. 872-877 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Estradiol
  • Eating
  • Estrogen Receptor Antagonists
  • Hormones

• Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs)

  Kieser, K. J., Kim, D. W., Carlson, K. E., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 22 2010, In: Journal of Medicinal Chemistry. 53, 8, p. 3320-3329 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • acrylic acid
  • Ligands
  • bicyclo(3.3.1)nonane
  • Cyclofenil

• Extranuclear estrogen receptor-α stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

  Wong, W. P. S., Tiano, J. P., Liu, S., Hewitt, S. C., Le May, C., Dalle, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Korach, K. S. & Mauvais-Jarvis, F., Jul 20 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 29, p. 13057-13062 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Insulin
  • Response Elements
  • Islets of Langerhans
  • Estrogens

• Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

  Stender, J. D., Kim, K., Charn, T. H., Komm, B., Chang, K. C. N., Kraus, W. L., Benner, C., Glass, C. K. & Katzenellenbogen, B. S., Aug 2010, In: Molecular and cellular biology. 30, 16, p. 3943-3955 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor alpha
  • Estrogen Receptors
  • Transcriptional Activation
  • Genome
  • Response Elements

• Genome-wide dynamics of chromatin binding of estrogen receptors α and β: Mutual restriction and competitive site selection

  Charn, T. H., Liu, E. T. B., Chang, E. C., Lee, Y. K., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 2010, In: Molecular Endocrinology. 24, 1, p. 47-59 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Chromatin
  • Binding Sites
  • Genome
  • Cytoplasmic and Nuclear Receptors

• Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

  Chambliss, K. L., Wu, Q., Oltmann, S., Konaniah, E. S., Umetani, M., Korach, K. S., Thomas, G. D., Mineo, C., Yuhanna, I. S., Kim, S. H., Madak-Erdogan, Z., Maggi, A., Dineen, S. P., Roland, C. L., Hui, D. Y., Brekken, R. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Shaul, P. W., Jul 1 2010, In: Journal of Clinical Investigation. 120, 7, p. 2319-2330 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Uterine Neoplasms
  • Dendrimers
  • Estrogen Receptors
  • Estrogens
  • Breast Neoplasms

• Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

  Marshall, G. M., Gherardi, S., Xu, N., Neiron, Z., Trahair, T., Scarlett, C. J., Chang, D. K., Liu, P. Y., Jankowski, K., Iraci, N., Haber, M., Norris, M. D., Keating, J., Sekyere, E., Jonquieres, G., Stossi, F., Katzenellenbogen, B. S., Biankin, A. V., Perini, G. & Liu, T., Nov 4 2010, In: Oncogene. 29, 44, p. 5957-5968 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclin G2
  • Histone Deacetylase 2
  • Histone Deacetylases
  • Up-Regulation
  • Neuroblastoma
• 2012

  Aryl hydrocarbon receptor modulation of estrogen receptor α-mediated gene regulation by a multimeric chromatin complex involving the two receptors and the coregulator RIP140

  Madak-Erdogan, Z. & Katzenellenbogen, B. S., 2012, In: Toxicological Sciences. 125, 2, p. 401-411 11 p., kfr300.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear Receptor Co-Repressor 1
  • Aryl Hydrocarbon Receptors
  • Gene expression
  • Estrogen Receptors
  • Chromatin

• Macrophage-elicited loss of estrogen receptor-α in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus

  Stossi, F., Madak-Erdoǧan, Z. & Katzenellenbogen, B. S., Apr 5 2012, In: Oncogene. 31, 14, p. 1825-1834 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitogen-Activated Protein Kinases
  • Estrogen Receptors
  • Macrophages
  • Breast Neoplasms
  • Macrophage Activation

• Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF^skp2 proteasomal complex

  Bhatt, S., Xiao, Z., Meng, Z. & Katzenellenbogen, B. S., May 2012, In: Molecular and cellular biology. 32, 10, p. 1928-1943 16 p.

  Research output: Contribution to journal › Article › peer-review

  • p38 Mitogen-Activated Protein Kinases
  • Estrogen Receptors
  • Phosphorylation
  • Breast Neoplasms
  • Estrogens

• Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

  Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In: Oncogene. 31, 1, p. 39-47 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Breast Cancer 3
  • Tamoxifen
  • MicroRNAs
  • Cell Survival
  • Down-Regulation

• Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA

  Park, S., Yoon, S., Zhao, Y., Park, S. E., Liao, L., Xu, J., Lydon, J. P., DeMayo, F. J., O'Malley, B. W., Bagchi, M. K. & Katzenellenbogen, B. S., Aug 1 2012, In: Endocrinology. 153, 8, p. 3982-3994 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Dosage
  • Cytoplasmic and Nuclear Receptors
  • Fertility
  • Infertility
  • Estrogen Receptors
• 2015

  Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

  Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C. M., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In: Science Translational Medicine. 7, 271, 271ra9.

  Research output: Contribution to journal › Article › peer-review

  • Endometriosis
  • Estrogen Receptors
  • Estrogens
  • Fertility
  • Ligands

• Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

  Paterni, I., Bertini, S., Granchi, C., Tuccinardi, T., Macchia, M., Martinelli, A., Caligiuri, I., Toffoli, G., Rizzolio, F., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Minutolo, F., Feb 12 2015, In: Journal of Medicinal Chemistry. 58, 3, p. 1184-1194 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Glioma
  • Estrogens
  • Heterografts
  • Ligands

• Ligand accessibility and bioactivity of a hormone-dendrimer conjugate depend on pH and pH history

  Kim, S. H., Madak-Erdogan, Z., Bae, S. C., Carlson, K. E., Mayne, C. G., Granick, S., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Aug 19 2015, In: Journal of the American Chemical Society. 137, 32, p. 10326-10335 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendrimers
  • Estrogens
  • Poly(amidoamine)
  • Hormones
  • Bioactivity

• Protective hematopoietic effect of estrogens in a mouse model of thrombosis: Respective roles of nuclear versus membrane estrogen receptor α

  Valera, M. C., Fontaine, C., Lenfant, F., Cabou, C., Guillaume, M., Smirnova, N., Kim, S. H., Chambon, P., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Payrastre, B. & Arnal, J. F., Nov 2015, In: Endocrinology. 156, 11, p. 4293-4301 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor alpha
  • Nuclear Envelope
  • Estrogen Receptors
  • Estrogens
  • Thrombosis

• Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

  Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In: Nature communications. 6, 8303.

  Research output: Contribution to journal › Article › peer-review

  • Neuroglia
  • Molecules
  • axons
  • molecules
  • prohibitin

• The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

  Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In: Circulation Research. 117, 9, p. 770-777 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Neointima
  • Estrogen Receptor alpha
  • Estrogen Receptors
  • Smooth Muscle Myocytes
  • Vascular Smooth Muscle
• 2016

  Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

  Madak-Erdogan, Z., Kim, S. H., Gong, P., Zhao, Y. C., Zhang, H., Chambliss, K. L., Carlson, K. E., Mayne, C. G., Shaul, P. W., Korach, K. S., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., May 24 2016, In: Science Signaling. 9, 429, ra53.

  Research output: Contribution to journal › Article › peer-review

  • Tissue
  • Estrogens
  • Blood Vessels
  • Ligands
  • Estrogen Receptors

• Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland

  Madak-Erdogan, Z., Gong, P., Zhao, Y. C., Xu, L., Wrobel, K. U., Hartman, J. A., Wang, M., Cam, A., Iwaniec, U. T., Turner, R. T., Twaddle, N. C., Doerge, D. R., Khan, I. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Helferich, W. G., Feb 1 2016, In: Molecular Nutrition and Food Research. 60, 2, p. 369-380 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Glycyrrhiza
  • licorice
  • fatty liver
  • isoliquiritigenin
  • Human Mammary Glands

• Differential utilization of nuclear and extranuclear receptor signaling pathways in the actions of estrogens, SERMs, and a tissue-selective estrogen complex (TSEC)

  Madak-Erdogan, Z., Gong, P. & Katzenellenbogen, B. S., Apr 1 2016, In: Journal of Steroid Biochemistry and Molecular Biology. 158, p. 198-206 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Conjugated (USP) Estrogens
  • Selective Estrogen Receptor Modulators
  • Cytoplasmic and Nuclear Receptors
  • Tissue
  • Estrogens

• Endocrine treatment in breast cancer: Cure, resistance and beyond

  Tryfonidis, K., Zardavas, D., Katzenellenbogen, B. S. & Piccart, M., Nov 1 2016, In: Cancer Treatment Reviews. 50, p. 68-81 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Breast Neoplasms
  • Tumor Microenvironment
  • Therapeutics
  • Hormones
  • Biomarkers

• Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

  Fanning, S. W., Mayne, C. G., Dharmarajan, V., Carlson, K. E., Martin, T. A., Novick, S. J., Toy, W., Green, B., Panchamukhi, S., Katzenellenbogen, B. S., Tajkhorshid, E., Griffin, P. R., Shen, Y., Chandarlapaty, S., Katzenellenbogen, J. A. & Greene, G. L., Feb 2 2016, In: eLife. 5, FEBRUARY2016, e12792.

  Research output: Contribution to journal › Article › peer-review

  • Conformations
  • Estrogen Receptor alpha
  • Estrogen Receptor Modulators
  • Breast Neoplasms
  • Mutation

• Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells

  Gong, P., Madak-Erdogan, Z., Flaws, J. A., Shapiro, D. J., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 5 2016, In: Molecular and Cellular Endocrinology. 437, p. 190-200 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aryl Hydrocarbon Receptors
  • Estrogen Receptors
  • Estrogens
  • Gene expression
  • Crosstalk

• Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities

  Boonmuen, N., Gong, P., Ali, Z., Chittiboyina, A. G., Khan, I., Doerge, D. R., Helferich, W. G., Carlson, K. E., Martin, T., Piyachaturawat, P., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2016, In: Steroids. 105, p. 42-49 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary supplements
  • liquiritigenin
  • isoliquiritigenin
  • Glycyrrhiza
  • Selective Estrogen Receptor Modulators

• Multiple beneficial roles of repressor of estrogen receptor activity (REA) in suppressing the progression of endometriosis

  Zhao, Y., Chen, Y., Kuang, Y., Bagchi, M. K., Taylor, R. N., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Feb 2016, In: Endocrinology. 157, 2, p. 900-912 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Endometriosis
  • Estrogen Receptors
  • Tissue Donors
  • prohibitin
  • Estradiol Receptors

• Nonnuclear estrogen receptor activation improves hepatic steatosis in female mice

  Chambliss, K. L., Barrera, J., Umetani, M., Umetani, J., Kim, S. H., Madak-Erdogan, Z., Huang, L., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C. & Shaul, P. W., 2016, In: Endocrinology. 157, 10, p. 3731-3741 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendrimers
  • Estrogen Receptors
  • Estrogens
  • Liver
  • Adiposity

• OCT-4: A novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells

  Bhatt, S., Stender, J. D., Joshi, S., Wu, G. & Katzenellenbogen, B. S., Nov 3 2016, In: Oncogene. 35, 44, p. 5722-5734 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Tamoxifen
  • Estrogen Receptors
  • Breast Neoplasms
  • Binding Sites
  • MCF-7 Cells

• Science Signaling podcast for 24 May 2016: Designer estrogens

  Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In: Science Signaling. 9, 429, pc13.

  Research output: Contribution to journal › Review article › peer-review

  • Webcasts
  • Estrogens
  • Metabolism
  • Bone
  • Estradiol Congeners

• The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

  Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In: Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

  Research output: Contribution to journal › Article › peer-review

  • dioscin
  • Dioscorea
  • Saponins
  • Cells
  • Breast Neoplasms
• 2017

  Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells

  Min, J., Guillen, V. S., Sharma, A., Zhao, Y., Ziegler, Y., Gong, P., Mayne, C. G., Srinivasan, S., Kim, S. H., Carlson, K. E., Nettles, K. W., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Jul 27 2017, In: Journal of Medicinal Chemistry. 60, 14, p. 6321-6336 16 p.

  Research output: Contribution to journal › Article › peer-review

  • acrylic acid
  • Estrogen Receptor Modulators
  • Estrogen Receptors
  • Breast Neoplasms
  • Down-Regulation

• Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

  Nelson, A. W., Groen, A. J., Miller, J. L., Warren, A. Y., Holmes, K. A., Tarulli, G. A., Tilley, W. D., Katzenellenbogen, B. S., Hawse, J. R., Gnanapragasam, V. J. & Carroll, J. S., Jan 15 2017, In: Molecular and Cellular Endocrinology. 440, p. 138-150 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor beta
  • Cells
  • Estrogen Receptors
  • Tissue
  • Cell Line

• Estrogen Receptor-β Modulation of the ERα-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer

  Lu, W. & Katzenellenbogen, B. S., Aug 1 2017, In: Hormones and Cancer. 8, 4, p. 230-242 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Breast Neoplasms
  • Apoptosis
  • Gene Expression
  • Histones

• Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms

  Martin, A., Yu, J., Xiong, J., Khalid, A. B., Katzenellenbogen, B., Kim, S. H., Katzenellenbogen, J. A., Malaivijitnond, S., Gabet, Y., Krum, S. A. & Frenkel, B., Dec 2017, In: Journal of Cellular Physiology. 232, 12, p. 3798-3807 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Osteoblasts
  • Dihydrotestosterone
  • Androgens
  • Membranes
  • Estrogens

• Full antagonism of the estrogen receptor without a prototypical ligand side chain

  Srinivasan, S., Nwachukwu, J. C., Bruno, N. E., Dharmarajan, V., Goswami, D., Kastrati, I., Novick, S., Nowak, J., Cavett, V., Zhou, H. B., Boonmuen, N., Zhao, Y., Min, J., Frasor, J., Katzenellenbogen, B. S., Griffin, P. R., Katzenellenbogen, J. A. & Nettles, K. W., Jan 1 2017, In: Nature chemical biology. 13, 1, p. 111-118 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Ligands
  • Breast Neoplasms
  • Chemoprevention
  • Patient Compliance

• Membrane and nuclear estrogen receptor alpha actions: From tissue specificity to medical implications

  Arnal, J. F., Lenfant, F., Metivier, R., Flouriot, G., Henrion, D., Adlanmerini, M., Fontaine, C., Gourdy, P., Chambon, P., Katzenellenbogen, B. & Katzenellenbogen, J., Jul 2017, In: Physiological Reviews. 97, 3, p. 1045-1087 43 p.

  Research output: Contribution to journal › Review article › peer-review

  • Organ Specificity
  • Estrogen Receptor alpha
  • Nuclear Envelope
  • Steroids
  • Membranes

• MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression

  Christenson, J. L., Butterfield, K. T., Spoelstra, N. S., Norris, J. D., Josan, J. S., Pollock, J. A., McDonnell, D. P., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Richer, J. K., Apr 1 2017, In: Hormones and Cancer. 8, 2, p. 69-77 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mouse mammary tumor virus
  • Triple Negative Breast Neoplasms
  • Androgen Receptors
  • Neoplasm Antigens
  • Breast Neoplasms

• Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice

  Menazza, S., Sun, J., Appachi, S., Chambliss, K. L., Kim, S. H., Aponte, A., Khan, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Shaul, P. W. & Murphy, E., Jun 1 2017, In: Journal of Molecular and Cellular Cardiology. 107, p. 41-51 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor alpha
  • Reperfusion Injury
  • Estrogen Receptors
  • Endothelium
  • Dendrimers

• Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors

  Zhao, Y., Laws, M. J., Guillen, V. S., Ziegler, Y., Min, J., Sharma, A., Kim, S. H., Chu, D., Park, B. H., Oesterreich, S., Mao, C., Shapiro, D. J., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 15 2017, In: Cancer Research. 77, 20, p. 5602-5613 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor Modulators
  • Estrogen Receptors
  • Breast Neoplasms
  • Neoplasms
  • Inbred NOD Mouse
• 2018

  Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain

  Sharma, A., Toy, W., Guillen, V. S., Sharma, N., Min, J., Carlson, K. E., Mayne, C. G., Lin, S., Sabio, M., Greene, G., Katzenellenbogen, B. S., Chandarlapaty, S. & Katzenellenbogen, J. A., Dec 21 2018, In: ACS chemical biology. 13, 12, p. 3374-3384 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor Modulators
  • Estrogen Receptors
  • Ligands
  • Cell proliferation
  • Breast Neoplasms

• New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons

  Wang, L., Guillen, V. S., Sharma, N., Flessa, K., Min, J., Carlson, K. E., Toy, W., Braqi, S., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Chandarlapaty, S. & Sharma, A., Aug 9 2018, In: ACS Medicinal Chemistry Letters. 9, 8, p. 803-808 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Scaffolds
  • Fulvestrant
  • Proteins
  • Cell proliferation

• Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice

  Miranda, C. L., Johnson, L. A., De Montgolfier, O., Elias, V. D., Ullrich, L. S., Hay, J. J., Paraiso, I. L., Choi, J., Reed, R. L., Revel, J. S., Kioussi, C., Bobe, G., Iwaniec, U. T., Turner, R. T., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Blakemore, P. R., Gombart, A. F., Maier, C. S., Raber, J. & 1 others, Stevens, J. F., Dec 1 2018, In: Scientific reports. 8, 1, 613.

  Research output: Contribution to journal › Article › peer-review

  • xanthohumol
  • Obese Mice
  • High Fat Diet
  • Cognitive Dysfunction
  • Insulin Resistance

• Predominant role of nuclear versus membrane estrogen receptor α in arterial protection: Implications for estrogen receptor α modulation in cardiovascular prevention/safety

  Guivarc’h, E., Buscato, M., Guihot, A. L., Favre, J., Vessières, E., Grimaud, L., Wakim, J., Melhem, N. J., Zahreddine, R., Adlanmerini, M., Loufrani, L., Knauf, C., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Foidart, J. M., Gourdy, P., Lenfant, F., Arnal, J. F., Henrion, D. & Fontaine, C., Jul 1 2018, In: Journal of the American Heart Association. 7, 13, e008950.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear Envelope
  • Estrogen Receptors
  • Safety
  • Estrogens
  • Estetrol

• Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: Implications for ERα modulation

  Vinel, A., Coudert, A. E., Buscato, M., Valera, M. C., Ostertag, A., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Berdal, A., Babajko, S., Arnal, J. F. & Fontaine, C., Aug 2018, In: Journal of Bone and Mineral Research. 33, 8, p. 1520-1531 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mandible
  • Estrogen Receptors
  • Bone and Bones
  • Membranes
  • Estrogens

• Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

  Selvaraj, U. M., Zuurbier, K. R., Whoolery, C. W., Plautz, E. J., Chambliss, K. L., Kong, X., Zhang, S., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C., Shaul, P. W. & Stowe, A. M., 2018, In: Endocrinology. 159, 11, p. 3848-3859 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Estrogens
  • Middle Cerebral Artery Infarction
  • Stroke
  • Uterine Neoplasms

• Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

  Katzenellenbogen, J. A., Mayne, C. G., Katzenellenbogen, B. S., Greene, G. L. & Chandarlapaty, S., Jun 1 2018, In: Nature Reviews Cancer. 18, 6, p. 377-388 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Estrogen Receptors
  • Ligands
  • Mutation
  • Androgen Receptors
  • Breast Neoplasms
• 2019

  Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

  Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In: npj Breast Cancer. 5, 1, 45.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Breast Neoplasms
  • Growth
  • Forkhead Box Protein M1
  • In Vitro Techniques
  • Triple Negative Breast Neoplasms