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• 2012

  1-methylthio-d-xylulose 5-phosphate methylsulfurylase: A novel route to 1-deoxy-d-xylulose 5-phosphate in Rhodospirillum rubrum

  Warlick, B. P., Evans, B. S., Erb, T. J., Ramagopal, U. A., Sriram, J., Imker, H. J., Sauder, J. M., Bonanno, J. B., Burley, S. K., Tabita, F. R., Almo, S. C., Sweedler, J. S. & Gerlt, J. A., Oct 23 2012, In: Biochemistry. 51, 42, p. 8324-8326 3 p.

  Research output: Contribution to journal › Article › peer-review

  • xylulose-5-phosphate
  • Rhodospirillum rubrum
  • ribose 1-phosphate
  • dimethyl disulfide
  • 5'-methylthioadenosine

• A hyphenated optical trap capillary electrophoresis laser induced native fluorescence system for single-cell chemical analysis

  Cecala, C., Rubakhin, S. S., Mitchell, J. W., Gillette, M. U. & Sweedler, J. V., Jul 7 2012, In: Analyst. 137, 13, p. 2965-2972 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Capillary electrophoresis
  • Optical Tweezers
  • Single-Cell Analysis
  • Capillary Electrophoresis
  • Fluorescence

• Analyses of pig genomes provide insight into porcine demography and evolution

  Groenen, M. A. M., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H. J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C., Auvil, L. & 116 others, Badaoui, B., Beattie, C. W., Bendixen, C., Berman, D., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Bujie, Z., Bystrom, M., Capitanu, B., Carvalho-Silva, D., Chardon, P., Chen, C., Cheng, R., Choi, S. H., Chow, W., Clark, R. C., Clee, C., Crooijmans, R. P. M. A., Dawson, H. D., Dehais, P., De Sapio, F., Dibbits, B., Drou, N., Du, Z. Q., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G. J., Fowler, K. E., Fredholm, M., Fritz, E., Gilbert, J. G. R., Giuffra, E., Gorodkin, J., Griffin, D. K., Harrow, J. L., Hayward, A., Howe, K., Hu, Z. L., Humphray, S. J., Hunt, T., Hornshoøj, H., Jeon, J. T., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Kim, J., Kim, J. H., Kim, K. W., Kim, T. H., Larson, G., Lee, K., Lee, K. T., Leggett, R., Lewin, H. A., Li, Y., Liu, W., Loveland, J. E., Lu, Y., Lunney, J. K., Ma, J., Madsen, O., Mann, K., Matthews, L., McLaren, S., Morozumi, T., Murtaugh, M. P., Narayan, J., Nguyen, D. T., Ni, P., Oh, S. J., Onteru, S., Panitz, F., Park, E. W., Park, H. S., Pascal, G., Paudel, Y., Perez-Enciso, M., Ramirez-Gonzalez, R., Reecy, J. M., Rodriguez-Zas, S., Rohrer, G. A., Rund, L., Sang, Y., Schachtschneider, K., Schraiber, J. G., Schwartz, J., Scobie, L., Scott, C., Searle, S., Servin, B., Southey, B. R., Sperber, G., Stadler, P., Sweedler, J. V., Tafer, H., Thomsen, B., Wali, R., Wang, J., Wang, J., White, S., Xu, X., Yerle, M., Zhang, G., Zhang, J., Zhang, J., Zhao, S., Rogers, J., Churcher, C. & Schook, L. B., Nov 15 2012, In: Nature. 491, 7424, p. 393-398 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Sus scrofa
  • Swine
  • Genome
  • Demography
  • Smell

• Analytical chemistry: The synergies between the division and the journal

  Sweedler, J. V. & Koppenaal, D. W., Nov 6 2012, In: Analytical chemistry. 84, 21, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• An enhanced protein crosslink identification strategy using CID-cleavable chemical crosslinkers and LC/MS ⁿ analysis

  Liu, F., Wu, C., Sweedler, J. V. & Goshe, M. B., Feb 2012, In: Proteomics. 12, 3, p. 401-405 5 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Peptides
  • aspartyl-proline
  • Cross-Linking Reagents
  • Proteins
  • Optical resolving power

• A protease for 'middle-down' proteomics

  Wu, C., Tran, J. C., Zamdborg, L., Durbin, K. R., Li, M., Ahlf, D. R., Early, B. P., Thomas, P. M., Sweedler, J. V. & Kelleher, N. L., Aug 1 2012, In: Nature Methods. 9, 8, p. 822-824 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Peptide Hydrolases
  • Peptides
  • Proteolysis
  • Membranes

• Are we growing more picky, more careless or simply under more pressure?

  Sweedler, J. V., Aug 7 2012, In: Analytical chemistry. 84, 15, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis

  Erb, T. J., Evans, B. S., Cho, K., Warlick, B. P., Sriram, J., Wood, B. M. K., Imker, H. J., Sweedler, J. V., Tabita, F. R. & Gerlt, J. A., Nov 2012, In: Nature chemical biology. 8, 11, p. 926-932 7 p.

  Research output: Contribution to journal › Article › peer-review

  • ribulose-1,5 diphosphate
  • Oxygenases
  • link protein
  • Terpenes
  • Rhodospirillum rubrum

• Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons

  Wang, T. A., Yu, Y. V., Govindaiah, G., Ye, X., Artinian, L., Coleman, T. P., Sweedler, J. V., Cox, C. L. & Gillette, M. U., Aug 17 2012, In: Science. 337, 6096, p. 839-842 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Suprachiasmatic Nucleus Neurons
  • Suprachiasmatic Nucleus
  • Circadian Rhythm
  • Circadian Clocks
  • Potassium Channels

• Collaborators, colleagues, and friends need not be listed

  Sweedler, J. V., May 1 2012, In: Analytical chemistry. 84, 9, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Comparative peptidomics analysis of neural adaptations in rats repeatedly exposed to amphetamine

  Romanova, E. V., Lee, J. E., Kelleher, N. L., Sweedler, J. V. & Gulley, J. M., Nov 2012, In: Journal of Neurochemistry. 123, 2, p. 276-287 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Rats
  • Amphetamine
  • Mass spectrometry
  • Peptides
  • Liquid chromatography

• D-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems

  Ota, N., Shi, T. & Sweedler, J. V., Nov 2012, In: Amino Acids. 43, 5, p. 1873-1886 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • D-Aspartic Acid
  • Neurosecretory Systems
  • Neurology
  • Molecules
  • Nervous System

• Don't grow your article too long: We do have length guidelines

  Sweedler, J. V., Jul 3 2012, In: Analytical chemistry. 84, 13, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Evaluation of database search programs for accurate detection of neuropeptides in tandem mass spectrometry experiments

  Akhtar, M. N., Southey, B. R., Andrén, P. E., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 7 2012, In: Journal of Proteome Research. 11, 12, p. 6044-6055 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Neuropeptides
  • Peptides
  • Databases

• Filling Royce's shoes

  Sweedler, J., Jan 3 2012, In: Analytical chemistry. 84, 1, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• First survey and functional annotation of prohormone and convertase genes in the pig

  Porter, K. I., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., Nov 15 2012, In: BMC genomics. 13, 1, 582.

  Research output: Contribution to journal › Article › peer-review

  • Proprotein Convertases
  • Swine
  • Urocortins
  • Neuropeptides
  • Genes

• Glial D-serine gates NMDA receptors at excitatory synapses in prefrontal cortex

  Fossat, P., Turpin, F. R., Sacchi, S., Dulong, J., Shi, T., Rivet, J. M., Sweedler, J. V., Pollegioni, L., Millan, M. J., Oliet, S. H. R. & Mothet, J. P., Mar 2012, In: Cerebral Cortex. 22, 3, p. 595-606 12 p.

  Research output: Contribution to journal › Article › peer-review

  • N-Methyl-D-Aspartate Receptors
  • Synapses
  • Prefrontal Cortex
  • Neuroglia
  • Glycine

• Label-free quantitation of peptide release from neurons in a microfluidic device with mass spectrometry imaging

  Zhong, M., Lee, C. Y., Croushore, C. A. & Sweedler, J. V., May 8 2012, In: Lab on a chip. 12, 11, p. 2037-2045 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Lab-On-A-Chip Devices
  • Peptides
  • Mass spectrometry
  • Microfluidics
  • Neurons

• Let's get social

  Sweedler, J. V., Apr 3 2012, In: Analytical chemistry. 84, 7, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Mass spectrometry imaging and profiling of single cells

  Lanni, E. J., Rubakhin, S. S. & Sweedler, J. V., Aug 30 2012, In: Journal of Proteomics. 75, 16, p. 5036-5051 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Mass spectrometry
  • Secondary Ion Mass Spectrometry
  • Mass Spectrometry
  • Imaging techniques
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

• Mechanical tension modulates local and global vesicle dynamics in neurons

  Ahmed, W. W., Li, T. C., Rubakhin, S. S., Chiba, A., Sweedler, J. V. & Saif, T. A., Jun 2012, In: Cellular and Molecular Bioengineering. 5, 2, p. 155-164 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Vesicles
  • Neuron
  • Aplysia
  • Drosophila
  • Neurons

• Metabolomics in analytical chemistry

  Sweedler, J. V., Jul 17 2012, In: Analytical chemistry. 84, 14, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Microfluidic device for the selective chemical stimulation of neurons and characterization of peptide release with mass spectrometry

  Croushore, C. A., Supharoek, S. A., Lee, C. Y., Jakmunee, J. & Sweedler, J. V., Nov 6 2012, In: Analytical Chemistry. 84, 21, p. 9446-9452 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Microfluidics
  • Neurons
  • Characterization (materials science)
  • Peptides

• Now it is a highlight, not an acceleration

  Sweedler, J. V., Sep 4 2012, In: Analytical chemistry. 84, 17, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Peptidomic analyses of mouse astrocytic cell lines and rat primary cultured astrocytes

  Yin, P., Knolhoff, A. M., Rosenberg, H. J., Millet, L. J., Gillette, M. U. & Sweedler, J. V., Aug 3 2012, In: Journal of Proteome Research. 11, 8, p. 3965-3973 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Astrocytes
  • Rats
  • Cells
  • Peptides
  • Cell Line

• Professional Editors or Scientist Editors? Both perspectives have value.

  Sweedler, J. V., Mar 6 2012, In: Analytical chemistry. 84, 5, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Rejections with editorial expertise and without external review: Are these fair?

  Sweedler, J. V., Dec 4 2012, In: Analytical chemistry. 84, 23, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Relative quantitation of neuropeptides over a thousand-fold concentration range

  Hou, X., Xie, F. & Sweedler, J. V., Dec 2012, In: Journal of the American Society for Mass Spectrometry. 23, 12, p. 2083-2093 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Neuropeptides
  • Mass Spectrometry
  • Electrospray ionization
  • Ionization

• Reviews, perspectives, features: What's the difference?

  Sweedler, J. V., Feb 7 2012, In: Analytical chemistry. 84, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Sampling techniques for single-cell electrophoresis

  Cecala, C. & Sweedler, J. V., Jul 7 2012, In: Analyst. 137, 13, p. 2922-2929 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Electrophoresis
  • sampling technique
  • electrokinesis
  • Sampling
  • Fluorescence

• Secondary ion mass spectrometry imaging of molecular distributions in cultured neurons and their processes: Comparative analysis of sample preparation

  Tucker, K. R., Li, Z., Rubakhin, S. S. & Sweedler, J. V., Nov 2012, In: Journal of the American Society for Mass Spectrometry. 23, 11, p. 1931-1938 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary Ion Mass Spectrometry
  • Secondary ion mass spectrometry
  • Molecular Imaging
  • Neurons
  • Imaging techniques

• Serotonin of mast cell origin contributes to hippocampal function

  Nautiyal, K. M., Dailey, C. A., Jahn, J. L., Rodriquez, E., Son, N. H., Sweedler, J. V. & Silver, R., Aug 2012, In: European Journal of Neuroscience. 36, 3, p. 2347-2359 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Mast Cells
  • Serotonin
  • Neurogenesis
  • Hippocampus
  • Fluoxetine

• Single-cell metabolomics: Changes in the metabolome of freshly isolated and cultured neurons

  Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Oct 17 2012, In: ACS Chemical Neuroscience. 3, 10, p. 782-792 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolome
  • Neurons
  • Glycerol
  • Metabolites

• Targeted single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons

  Neupert, S., Rubakhin, S. S. & Sweedler, J. V., Aug 24 2012, In: Chemistry and Biology. 19, 8, p. 1010-1019 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Single-Cell Analysis
  • paraform
  • Mass spectrometry
  • Neuropeptides
  • Molecules

• The Hypothalamic-Neurohypophyseal System: From Genome to Physiology

  Murphy, D., Konopacka, A., Hindmarch, C., Paton, J. F. R., Sweedler, J. V., Gillette, M. U., Ueta, Y., Grinevich, V., Lozic, M. & Japundzic-Zigon, N., Apr 2012, In: Journal of Neuroendocrinology. 24, 4, p. 539-553 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Oxytocin
  • Genome
  • Optogenetics
  • Neuroanatomy
  • Breeding

• Therapeutic peptide production in Drosophila

  Park, D., Hou, X., Sweedler, J. V. & Taghert, P. H., Aug 2012, In: Peptides. 36, 2, p. 251-256 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Drosophila
  • Peptides
  • Metabolic Engineering
  • Metabolic engineering
  • Synthetic Chemistry Techniques

• Two unrelated items to avoid, one for me and one for you

  Sweedler, J. V., Jun 5 2012, In: Analytical chemistry. 84, 11, p. 4635-4636 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Urotensin II in Invertebrates: From Structure to Function in Aplysia californica

  Romanova, E. V., Sasaki, K., Alexeeva, V., Vilim, F. S., Jing, J., Richmond, T. A., Weiss, K. R. & Sweedler, J. V., Nov 8 2012, In: PloS one. 7, 11, e48764.

  Research output: Contribution to journal › Article › peer-review

  • Invertebrates
  • urotensin II
  • Aplysia californica
  • Aplysia
  • invertebrates
• 2011

  A diverse family of novel peptide toxins from an unusual cone snail, Conus californicus

  Gilly, W. F., Richmond, T. A., Duda, T. F., Elliger, C., Lebaric, Z., Schulz, J., Bingham, J. P. & Sweedler, J. V., Jan 2011, In: Journal of Experimental Biology. 214, 1, p. 147-161 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Conus Snail
  • Conus
  • seed cones
  • snail
  • toxin

• A novel pyridoxal 5'-phosphate-dependent amino acid racemase in the aplysia californica central nervous system

  Wang, L., Ota, N., Romanova, E. V. & Sweedler, J. V., Apr 15 2011, In: Journal of Biological Chemistry. 286, 15, p. 13765-13774 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Isomerases
  • aspartate racemase
  • D-Aspartic Acid
  • Aplysia
  • Pyridoxal Phosphate

• Chronic morphine alters the presynaptic protein profile: Identification of novel molecular targets using proteomics and network analysis

  Abul-Husn, N. S., Annangudi, S. P., Ma'ayan, A., Ramos-Ortolaza, D. L., Stockton, S. D., Gomes, I., Sweedler, J. V. & Devi, L. A., Oct 17 2011, In: PloS one. 6, 10, e25535.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • morphine
  • Electric network analysis
  • protein composition
  • Morphine

• Collection of peptides released from single neurons with particle-embedded monolithic capillaries followed by detection with matrix-assisted laser desorption/ionization mass spectrometry

  Fan, Y., Rubakhin, S. & Sweedler, J. V., Dec 15 2011, In: Analytical Chemistry. 83, 24, p. 9557-9563 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Desorption
  • Pyrrolidinones
  • ethylenediamine

• Comparison of tandem mass spectrometry search methods to identify neuropeptides

  Akhtar, M. N., Southey, B. R., Porter, K. I., Sweedler, J. V. & Rodriguez-Zas, S. L., 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 982-984 3 p. 6112530. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Neuropeptides
  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Peptides
  • Amino acids

• Direct cellular peptidomics of hypothalamic neurons

  Mitchell, J. W., Atkins, N., Sweedler, J. V. & Gillette, M. U., Oct 2011, In: Frontiers in Neuroendocrinology. 32, 4, p. 377-386 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neurons
  • Peptides
  • Cell signaling
  • Supraoptic Nucleus
  • Suprachiasmatic Nucleus

• Distinguishing endogenous d-amino acid-containing neuropeptides in individual neurons using tandem mass spectrometry

  Bai, L., Romanova, E. V. & Sweedler, J. V., Apr 1 2011, In: Analytical Chemistry. 83, 7, p. 2794-2800 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Neuropeptides
  • Neurons
  • Amino Acids
  • Peptides

• Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history

  Elliger, C. A., Richmond, T. A., Lebaric, Z. N., Pierce, N. T., Sweedler, J. V. & Gilly, W. F., Feb 2011, In: Toxicon. 57, 2, p. 311-322 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Conotoxins
  • History
  • Peptides
  • Molluscs
  • Gene encoding

• Integration of sequence and functional information to identify and annotate neuropeptides in the pig genome

  Porter, K. I., Southey, B. R., Akhtar, M. N., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 988-990 3 p. 6112532. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Neuropeptides
  • Genes
  • Swine
  • Genome
  • proenkephalin

• MALDI mass spectrometry imaging of neuronal cell cultures

  Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 2011, In: Journal of the American Society for Mass Spectrometry. 22, 5, p. 828-836 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell culture
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Aplysia
  • Mass Spectrometry

• Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry

  Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Sep 1 2011, In: Analytical chemistry. 83, 17, p. 6810-6817 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Mass spectrometry
  • Neurons
  • Metabolites

• Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord

  Miller, L. K., Hou, X., Rodriguiz, R. M., Gagnidze, K., Sweedler, J. V., Wetsel, W. C. & Devi, L. A., Dec 2011, In: Journal of Neurochemistry. 119, 5, p. 1074-1085 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin-Converting Enzymes
  • Morphine
  • Spinal Cord
  • Peptides
  • Neuropeptides