Find Research outputs — University of Illinois Urbana-Champaign

2020

A ferredoxin-dependent dihydropyrimidine dehydrogenase in Clostridium chromiireducens

Wang, F., Wei, Y., Lu, Q., Ang, E. L., Zhao, H. & Zhang, Y., Jul 2020, In: Bioscience Reports. 40, 7, BSR20201642.

Research output: Contribution to journal › Article › peer-review

Open Access

A genetic toolbox for metabolic engineering of Issatchenkia orientalis

Cao, M., Fatma, Z., Song, X., Hsieh, P. H., Tran, V. G., Lyon, W. L., Sayadi, M., Shao, Z., Yoshikuni, Y. & Zhao, H., May 2020, In: Metabolic Engineering. 59, p. 87-97 11 p.

Research output: Contribution to journal › Article › peer-review

A mass spectrometry-based high-throughput screening method for engineering fatty acid synthases with improved production of medium-chain fatty acids

Xue, P., Si, T., Mishra, S., Zhang, L., Choe, K., Sweedler, J. V. & Zhao, H., Jul 1 2020, In: Biotechnology and bioengineering. 117, 7, p. 2131-2138 8 p.

Research output: Contribution to journal › Article › peer-review

A New Biosensor for Stilbenes and a Cannabinoid Enabled by Genome Mining of a Transcriptional Regulator

Sun, H., Zhao, H. & Ang, E. L., Apr 17 2020, In: ACS synthetic biology. 9, 4, p. 698-705 8 p.

Research output: Contribution to journal › Article › peer-review

A pathway for degradation of uracil to acetyl coenzyme a in bacillus megaterium

Zhu, D., Wei, Y., Yin, J., Liu, D., Ang, E. L., Zhao, H. & Zhang, Y., Apr 1 2020, In: Applied and environmental microbiology. 86, 7, e02837.

Research output: Contribution to journal › Article › peer-review

A transaldolase-dependent sulfoglycolysis pathway in Bacillus megaterium DSM 1804

Liu, Y., Wei, Y., Zhou, Y., Ang, E. L., Zhao, H. & Zhang, Y., Dec 17 2020, In: Biochemical and Biophysical Research Communications. 533, 4, p. 1109-1114 6 p.

Research output: Contribution to journal › Article › peer-review

Biosynthetic engineering of the antifungal, anti-MRSA auroramycin

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Ching, K. C., Tsai, D. J., Jhang, Y. W., Lauderdale, T. L., Shia, K. S., Zhao, H., Ang, E. L., Zhang, M. M., Lim, Y. H. & Wong, F. T., Jan 6 2020, In: Microbial cell factories. 19, 1, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

Biosystems design by directed evolution

Wang, Y., Yu, X. & Zhao, H., Mar 1 2020, In: AIChE Journal. 66, 3, e16716.

Research output: Contribution to journal › Review article › peer-review

Biosystems Design by Machine Learning

Volk, M. J., Lourentzou, I., Mishra, S., Vo, L. T., Zhai, C. & Zhao, H., Jul 17 2020, In: ACS synthetic biology. 9, 7, p. 1514-1533 20 p.

Research output: Contribution to journal › Article › peer-review

Computational Tools for Discovering and Engineering Natural Product Biosynthetic Pathways

Ren, H., Shi, C. & Zhao, H., Jan 24 2020, In: iScience. 23, 1, 100795.

Research output: Contribution to journal › Review article › peer-review

Open Access

Discovery and Characterization of a Class IV Lanthipeptide with a Nonoverlapping Ring Pattern

Ren, H., Shi, C., Bothwell, I. R., Van Der Donk, W. A., Van Der Donk, W. A., Van Der Donk, W. A., Zhao, H., Zhao, H., Zhao, H., Zhao, H. & Zhao, H., Jun 19 2020, In: ACS chemical biology. 15, 6, p. 1642-1649 8 p.

Research output: Contribution to journal › Article › peer-review

DNA punch cards for storing data on native DNA sequences via enzymatic nicking

Tabatabaei, S. K., Wang, B., Athreya, N. B. M., Enghiad, B., Hernandez, A. G., Fields, C. J., Leburton, J. P., Soloveichik, D., Zhao, H. & Milenkovic, O., Dec 1 2020, In: Nature communications. 11, 1, 1742.

Research output: Contribution to journal › Article › peer-review

Open Access

Emerging molecular biology tools and strategies for engineering natural product biosynthesis

Xu, W., Klumbys, E., Ang, E. L. & Zhao, H., Jun 2020, In: Metabolic Engineering Communications. 10, e00108.

Research output: Contribution to journal › Review article › peer-review

Open Access

Evolutionary context-integrated deep sequence modeling for protein engineering

Luo, Y., Vo, L., Ding, H., Su, Y., Liu, Y., Qian, W. W., Zhao, H. & Peng, J., 2020, Research in Computational Molecular Biology - 24th Annual International Conference, RECOMB 2020, Proceedings. Schwartz, R. (ed.). Springer, p. 261-263 3 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12074 LNBI).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fine-tuning the regulation of Cas9 expression levels for efficient CRISPR-Cas9 mediated recombination in Streptomyces

Ye, S., Enghiad, B., Zhao, H. & Takano, E., May 1 2020, In: Journal of Industrial Microbiology and Biotechnology. 47, 4-5, p. 413-423 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Genome-scale metabolic reconstruction of the non-model yeast Issatchenkia orientalis SD108 and its application to organic acids production

Suthers, P. F., Dinh, H. V., Fatma, Z., Shen, Y., Chan, S. H. J., Rabinowitz, J. D., Zhao, H. & Maranas, C. D., Dec 2020, In: Metabolic Engineering Communications. 11, p. e00148 e00148.

Research output: Contribution to journal › Article › peer-review

Open Access

Identification and Characterization of Citrus Peel Uronic Acid Oxidase

Wei, Y., Tan, Y. L., Ang, E. L. & Zhao, H., Mar 16 2020, In: ChemBioChem. 21, 6, p. 797-800 4 p.

Research output: Contribution to journal › Article › peer-review

Integrating biocatalysis with chemocatalysis for selective transformations

Huang, X., Cao, M. & Zhao, H., Apr 2020, In: Current Opinion in Chemical Biology. 55, p. 161-170 10 p.

Research output: Contribution to journal › Review article › peer-review

Optically guided mass spectrometry to screen microbial colonies for directed enzyme evolution

Xue, P., Si, T. & Zhao, H., 2020, Methods in Enzymology. Tawfik, D. S. (ed.). Academic Press Inc., p. 255-273 19 p. (Methods in Enzymology; vol. 644).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Photoenzymatic enantioselective intermolecular radical hydroalkylation

Huang, X., Wang, B., Wang, Y., Jiang, G., Feng, J. & Zhao, H., Aug 6 2020, In: Nature. 584, 7819, p. 69-74 6 p.

Research output: Contribution to journal › Article › peer-review

Recent advances in domesticating non-model microorganisms

Fatma, Z., Schultz, J. C. & Zhao, H., Sep 1 2020, In: Biotechnology Progress. 36, 5, e3008.

Research output: Contribution to journal › Review article › peer-review

Reconstruction of Lead Acid Battery Negative Electrodes after Hard Sulfation Using Controlled Chelation Chemistry

Gossage, Z. T., Guo, F., Hatfield, K. O., Martin, T. A., Tian, Q., Gao, E. J., Kumar, A., Rodríguez-López, J. & Zhao, H., Jan 9 2020, In: Journal of the Electrochemical Society. 167, 12, 120537.

Research output: Contribution to journal › Article › peer-review

Stereoconvergent Reduction of Activated Alkenes by a Nicotinamide Free Synergistic Photobiocatalytic System

Wang, Y., Huang, X., Hui, J., Vo, L. T. & Zhao, H., Aug 21 2020, In: ACS Catalysis. 10, 16, p. 9431-9437 7 p.

Research output: Contribution to journal › Article › peer-review

Towards oilcane: Engineering hyperaccumulation of triacylglycerol into sugarcane stems

Parajuli, S., Kannan, B., Karan, R., Sanahuja, G., Liu, H., Garcia-Ruiz, E., Kumar, D., Singh, V., Zhao, H., Long, S., Shanklin, J. & Altpeter, F., Jul 1 2020, In: GCB Bioenergy. 12, 7, p. 476-490 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Two-Color Imaging of Nonrepetitive Endogenous Loci in Human Cells

Tasan, I., Su, C. J., Enghiad, B., Zhang, M., Mishra, S. & Zhao, H., Sep 18 2020, In: ACS synthetic biology. 9, 9, p. 2502-2514 13 p.

Research output: Contribution to journal › Article › peer-review

Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate

Liu, J., Wei, Y., Lin, L., Teng, L., Yin, J., Lu, Q., Chen, J., Zheng, Y., Li, Y., Xu, R., Zhai, W., Liu, Y., Liu, Y., Cao, P., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jul 7 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 27, p. 15599-155608 140010 p.

Research output: Contribution to journal › Article › peer-review

Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

Wang, B. & Zhao, H., Mar 2020, In: Synthetic and Systems Biotechnology. 5, 1, p. 21-22 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Unlocking nature's biosynthetic potential by directed genome evolution

Cao, M., Tran, V. G. & Zhao, H., Dec 2020, In: Current Opinion in Biotechnology. 66, p. 95-104 10 p.

Research output: Contribution to journal › Review article › peer-review

Unraveling the iterative type I polyketide synthases hidden in Streptomyces

Wang, B., Guo, F., Huang, C. & Zhao, H., Apr 14 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 15, p. 8449-8454 6 p.

Research output: Contribution to journal › Article › peer-review

2018

A coupled chlorinase-fluorinase system with a high efficiency of trans -halogenation and a shared substrate tolerance

Sun, H., Zhao, H. & Ang, E. L., 2018, In: Chemical Communications. 54, 68, p. 9458-9461 4 p.

Research output: Contribution to journal › Article › peer-review

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

Lian, J., HamediRad, M. & Zhao, H., Sep 2018, In: Biotechnology Journal. 13, 9, 1700601.

Research output: Contribution to journal › Review article › peer-review

Applying advanced dna assembly methods to generate pathway libraries

Eriksen, D. T., Chao, R. & Zhao, H., Mar 15 2018, Synthetic Biology: Parts, Devices and Applications. Wiley-VCH Verlag, p. 331-347 17 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation

Lim, Y. H., Wong, F. T., Yeo, W. L., Ching, K. C., Lim, Y. W., Heng, E., Chen, S., Tsai, D. J., Lauderdale, T. L., Shia, K. S., Ho, Y. S., Hoon, S., Ang, E. L., Zhang, M. M. & Zhao, H., Aug 16 2018, In: ChemBioChem. 19, 16, p. 1716-1719 4 p.

Research output: Contribution to journal › Article › peer-review

Biocatalysis for the synthesis of pharmaceuticals and pharmaceutical intermediates

Sun, H., Zhang, H., Ang, E. L. & Zhao, H., Apr 1 2018, In: Bioorganic and Medicinal Chemistry. 26, 7, p. 1275-1284 10 p.

Research output: Contribution to journal › Review article › peer-review

Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis

Litman, Z. C., Wang, Y., Zhao, H. & Hartwig, J. F., Aug 16 2018, In: Nature. 560, 7718, p. 355-359 5 p.

Research output: Contribution to journal › Article › peer-review

CRISPR/Cas9-mediated knock-in of an optimized TetO repeat for live cell imaging of endogenous loci

Tasan, I., Sustackova, G., Zhang, L., Kim, J., Sivaguru, M., HamediRad, M., Wang, Y., Genova, J., Ma, J., Belmont, A. S. & Zhao, H., Sep 28 2018, In: Nucleic acids research. 46, 17, e100.

Research output: Contribution to journal › Article › peer-review

Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface

Limsakul, P., Peng, Q., Wu, Y., Allen, M. E., Liang, J., Remacle, A. G., Lopez, T., Ge, X., Kay, B. K., Zhao, H., Strongin, A. Y., Yang, X. L., Lu, S. & Wang, Y., Apr 19 2018, In: Cell chemical biology. 25, 4, p. 370-379.e4

Research output: Contribution to journal › Article › peer-review

Engineered CRISPR/Cas9 system for multiplex genome engineering of polyploid industrial yeast strains

Lian, J., Bao, Z., Hu, S. & Zhao, H., Jun 2018, In: Biotechnology and bioengineering. 115, 6, p. 1630-1635 6 p.

Research output: Contribution to journal › Article › peer-review

Expanding the boundary of biocatalysis: design and optimization of in vitro tandem catalytic reactions for biochemical production

Wang, Y., Ren, H. & Zhao, H., Mar 4 2018, In: Critical Reviews in Biochemistry and Molecular Biology. 53, 2, p. 115-129 15 p.

Research output: Contribution to journal › Review article › peer-review

Genome-scale engineering of Saccharomyces cerevisiae with single-nucleotide precision

Bao, Z., HamediRad, M., Xue, P., Xiao, H., Tasan, I., Chao, R., Liang, J. & Zhao, H., Jul 1 2018, In: Nature Biotechnology. 36, 6, p. 505-508 4 p.

Research output: Contribution to journal › Article › peer-review

Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes

Tapsin, S., Sun, M., Shen, Y., Zhang, H., Lim, X. N., Susanto, T. T., Yang, S. L., Zeng, G. S., Lee, J., Lezhava, A., Ang, E. L., Zhang, L. H., Wang, Y., Zhao, H., Nagarajan, N. & Wan, Y., Dec 1 2018, In: Nature communications. 9, 1, 1289.

Research output: Contribution to journal › Article › peer-review

Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole

Liu, D., Wei, Y., Liu, X., Zhou, Y., Jiang, L., Yin, J., Wang, F., Hu, Y., Nanjaraj Urs, A. N., Liu, Y., Ang, E. L., Zhao, S., Zhao, H. & Zhang, Y., Dec 1 2018, In: Nature communications. 9, 1, 4224.

Research output: Contribution to journal › Article › peer-review

Insights into Cell-Free Conversion of CO₂ to Chemicals by a Multienzyme Cascade Reaction

Singh, R. K., Singh, R., Sivakumar, D., Kondaveeti, S., Kim, T., Li, J., Sung, B. H., Cho, B. K., Kim, D. R., Kim, S. C., Kalia, V. C., Zhang, Y. H. P. J., Zhao, H., Kang, Y. C. & Lee, J. K., Dec 7 2018, In: ACS Catalysis. 8, 12, p. 11085-11093 9 p.

Research output: Contribution to journal › Article › peer-review

In vivo biosensors: mechanisms, development, and applications

Shi, S., Ang, E. L. & Zhao, H., Jul 1 2018, In: Journal of Industrial Microbiology and Biotechnology. 45, 7, p. 491-516 26 p.

Research output: Contribution to journal › Article › peer-review

Metabolic Engineering of Saccharomyces cerevisiae Using a Trifunctional CRISPR/Cas System for Simultaneous Gene Activation, Interference, and Deletion

Schultz, C., Lian, J. & Zhao, H., Jan 1 2018, Methods in Enzymology. Scrutton, N. (ed.). Academic Press Inc., p. 265-276 12 p. (Methods in Enzymology; vol. 608).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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