Find Research Outputs — University of Illinois at Urbana-Champaign

2012

A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency

Jeya, M., Kim, T. S., Kumar Tiwari, M., Li, J., Zhao, H. & Lee, J. K., Dec 2012, In: Molecular BioSystems. 8, 12, p. 3103-3106 4 p.

Research output: Contribution to journal › Article › peer-review

Biocatalyst development by directed evolution

Wang, M., Si, T. & Zhao, H., Jul 2012, In: Bioresource Technology. 115, p. 117-125 9 p.

Research output: Contribution to journal › Article › peer-review

Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae

Sun, J., Shao, Z., Zhao, H., Nair, N., Wen, F., Xu, J. H. & Zhao, H., Aug 2012, In: Biotechnology and bioengineering. 109, 8, p. 2082-2092 11 p.

Research output: Contribution to journal › Article › peer-review

CmlI is an N-oxygenase in the biosynthesis of chloramphenicol

Lu, H., Chanco, E. & Zhao, H., Sep 16 2012, In: Tetrahedron. 68, 37, p. 7651-7654 4 p.

Research output: Contribution to journal › Article › peer-review

Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration

Zou, Y., Zhang, H., Brunzelle, J. S., Johannes, T. W., Woodyer, R., Hung, J. E., Nair, N., Van Der Donk, W. A., Zhao, H. & Nair, S. K., May 29 2012, In: Biochemistry. 51, 21, p. 4263-4270 8 p.

Research output: Contribution to journal › Article › peer-review

Customized optimization of metabolic pathways by combinatorial transcriptional engineering

Du, J., Yuan, Y., Si, T., Lian, J. & Zhao, H., Oct 2012, In: Nucleic acids research. 40, 18, p. e142

Research output: Contribution to journal › Article › peer-review

Direct cloning of large genomic sequences

Cobb, R. E. & Zhao, H., May 1 2012, In: Nature Biotechnology. 30, 5, p. 405-406 2 p.

Research output: Contribution to journal › Short survey › peer-review

Direct conversion of xylan to ethanol by recombinant Saccharomyces cerevisiae strains displaying an engineered minihemicellulosome

Sun, J., Wen, F., Si, T., Xu, J. H. & Zhao, H., Jun 2012, In: Applied and environmental microbiology. 78, 11, p. 3837-3845 9 p.

Research output: Contribution to journal › Article › peer-review

Directed evolution: An evolving and enabling synthetic biology tool

Cobb, R. E., Si, T. & Zhao, H., Aug 1 2012, In: Current Opinion in Chemical Biology. 16, 3-4, p. 285-291 7 p.

Research output: Contribution to journal › Review article › peer-review

DNA assembler: A synthetic biology tool for characterizing and engineering natural product gene clusters

Shao, Z. & Zhao, H., 2012, Natural Product Biosynthesis by Microorganisms and Plants, Part C. Academic Press Inc., p. 203-224 22 p. (Methods in Enzymology; vol. 517).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

DNA assembler method for construction of zeaxanthin-producing strains of saccharomyces cerevisiae

Shao, Z., Luo, Y. & Zhao, H., 2012, Microbial Carotenoids From Fungi: Methods and Protocols. Jose-Luis, B. (ed.). p. 251-262 12 p. (Methods in Molecular Biology; vol. 898).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Improving the thermostability of lipase Lip2 from Yarrowia lipolytica

Wen, S., Tan, T. & Zhao, H., Dec 5 2012, In: Journal of Biotechnology. 164, 2, p. 248-253 6 p.

Research output: Contribution to journal › Article › peer-review

Investigation of the role of Arg301 identified in the X-ray structure of phosphite dehydrogenase

Hung, J. E., Fogle, E. J., Christman, H. D., Johannes, T. W., Zhao, H., Metcalf, W. W. & Van Der Donk, W. A., May 29 2012, In: Biochemistry. 51, 21, p. 4254-4262 9 p.

Research output: Contribution to journal › Article › peer-review

Mechanistic studies on the flavin:NADH reductase (PrnF) from Pseudomonas fluorescens involved in arylamine oxygenation

Tiwari, M. K., Singh, R. K., Lee, J. K. & Zhao, H., Feb 1 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 3, p. 1344-1347 4 p.

Research output: Contribution to journal › Article › peer-review

Mutagenic inverted repeats assisted genome engineering (MIRAGE) in saccharomyces cerevisiae: Deletion of gal7

Nair, N. U. & Zhao, H., Jan 20 2012, Microbial Metabolic Engineering: Methods and Protocols. Cheng, Q. (ed.). p. 63-73 11 p. (Methods in Molecular Biology; vol. 834).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease

Sun, N., Liang, J., Abil, Z. & Zhao, H., Mar 1 2012, In: Molecular BioSystems. 8, 4, p. 1255-1263 9 p.

Research output: Contribution to journal › Article › peer-review

Recent advances in targeted genome engineering in mammalian systems

Sun, N., Abil, Z. & Zhao, H., Sep 2012, In: Biotechnology Journal. 7, 9, p. 1074-1087 14 p.

Research output: Contribution to journal › Review article › peer-review

Role of conserved glycine in zinc-dependent medium chain dehydrogenase/reductase superfamily

Tiwari, M. K., Singh, R. K., Singh, R., Jeya, M., Zhao, H. & Lee, J. K., Jun 1 2012, In: Journal of Biological Chemistry. 287, 23, p. 19429-19439 11 p.

Research output: Contribution to journal › Article › peer-review

Strain Improvement via Evolutionary Engineering

Kim, B., Du, J. & Zhao, H., Oct 24 2012, Engineering Complex Phenotypes in Industrial Strains. John Wiley and Sons, p. 111-131 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

The Botrytis cinerea type III polyketide synthase shows unprecedented high catalytic efficiency toward long chain acyl-CoAs

Jeya, M., Kim, T. S., Tiwari, M. K., Li, J., Zhao, H. & Lee, J. K., Nov 1 2012, In: Molecular BioSystems. 8, 11, p. 2864-2867 4 p.

Research output: Contribution to journal › Article › peer-review

2013

Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster

Luo, Y., Huang, H., Liang, J., Wang, M., Lu, L., Shao, Z., Cobb, R. E. & Zhao, H., Dec 5 2013, In: Nature communications. 4, 2894.

Research output: Contribution to journal › Article › peer-review

Challenges and opportunities in synthetic biology for chemical engineers

Luo, Y., Lee, J. K. & Zhao, H., Nov 5 2013, In: Chemical Engineering Science. 103, p. 115-119 5 p.

Research output: Contribution to journal › Article › peer-review

Combinatorial design of a highly efficient xylose-utilizing pathway in Saccharomyces cerevisiae for the production of cellulosic biofuels

Kim, B., Du, J., Eriksen, D. T. & Zhao, H., Feb 2013, In: Applied and environmental microbiology. 79, 3, p. 931-941 11 p.

Research output: Contribution to journal › Article › peer-review

Construction and engineering of large biochemical pathways via DNA assembler

Shao, Z. & Zhao, H., 2013, Synthetic Biology. Polizzi, K. & Kontoravdi, C. (eds.). p. 85-106 22 p. (Methods in Molecular Biology; vol. 1073).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Construction and screening of an antigen-derived peptide library displayed on yeast cell surface for CD4⁺ T cell epitope identification

Wen, F. & Zhao, H., Sep 20 2013, Immunoproteomics: Methods and Protocols. Fulton, K. & Twine, S. (eds.). p. 245-264 20 p. (Methods in Molecular Biology; vol. 1061).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Coordinated induction of multi-gene pathways in Saccharomyces cerevisiae

Liang, J., Ning, J. C. & Zhao, H., Feb 2013, In: Nucleic acids research. 41, 4, p. e54

Research output: Contribution to journal › Article › peer-review

Customized optimization of metabolic pathways by combinatorial transcriptional engineering.

Yuan, Y., Du, J. & Zhao, H., Aug 2 2013, In: Methods in molecular biology (Clifton, N.J.). 985, p. 177-209 33 p.

Research output: Contribution to journal › Article › peer-review

Directed evolution: Past, present, and future

Cobb, R. E., Chao, R. & Zhao, H., May 2013, In: AIChE Journal. 59, 5, p. 1432-1440 9 p.

Research output: Contribution to journal › Article › peer-review

Directed evolution as a powerful synthetic biology tool

Cobb, R. E., Sun, N. & Zhao, H., Mar 15 2013, In: Methods. 60, 1, p. 81-90 10 p.

Research output: Contribution to journal › Review article › peer-review

Directed evolution of a cellobiose utilization pathway in Saccharomyces cerevisiae by simultaneously engineering multiple proteins

Eriksen, D. T., Hsieh, P. C. H., Lynn, P. & Zhao, H., Jun 26 2013, In: Microbial cell factories. 12, 1, 61.

Research output: Contribution to journal › Article › peer-review

Directed evolution of a highly efficient cellobiose utilizing pathway in an industrial saccharomyces cerevisiae strain

Yuan, Y. & Zhao, H., Nov 2013, In: Biotechnology and bioengineering. 110, 11, p. 2874-2881 8 p.

Research output: Contribution to journal › Article › peer-review

Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production

Rao, G., Lee, J. K. & Zhao, H., Jul 1 2013, In: Applied Microbiology and Biotechnology. 97, 13, p. 5861-5867 7 p.

Research output: Contribution to journal › Article › peer-review

Drug Discovery and Development via Synthetic Biology

Cobb, R. E., Luo, Y., Freestone, T. & Zhao, H., Aug 27 2013, Synthetic Biology. Elsevier Inc., p. 183-206 24 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Engineering novel tandem catalytic reactions using organometallic catalysts and metalloenzymes

Denard, C. A., Huang, H., Lu, L., Bartlett, M. J., Hartwig, J. F. & Zhao, H., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, 1 p. (Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Introduction

Zhao, H., Aug 27 2013, In: Synthetic Biology.

Research output: Contribution to journal › Article › peer-review

Investigating glucose and xylose metabolism in Saccharomyces cerevisiae and Scheffersomyces stipitis via ¹³C metabolic flux analysis

Feng, X. & Zhao, H., Sep 1 2013, In: AIChE Journal. 59, 9, p. 3195-3202 8 p.

Research output: Contribution to journal › Article › peer-review

Investigating host dependence of xylose utilization in recombinant Saccharomyces cerevisiae strains using RNA-seq analysis

Feng, X. & Zhao, H., 2013, In: Biotechnology for Biofuels. 6, 1, 96.

Research output: Contribution to journal › Article › peer-review

Investigating xylose metabolism in recombinant Saccharomyces cerevisiae via ¹³C metabolic flux analysis

Feng, X. & Zhao, H., Nov 18 2013, In: Microbial cell factories. 12, 1, 114.

Research output: Contribution to journal › Article › peer-review

Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization

Li, S., Ha, S. J., Kim, H. J., Galazka, J. M., Cate, J. H. D., Jin, Y. S. & Zhao, H., Oct 10 2013, In: Journal of Biotechnology. 168, 1, p. 1-6 6 p.

Research output: Contribution to journal › Article › peer-review

Modular assembly of designer Puf proteins for specific post-transcriptional regulation of endogenous RNA

Abil, Z. & Zhao, H., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, 1 p. (Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Multistep one-pot reactions combining biocatalysts and chemical catalysts for asymmetric synthesis

Denard, C. A., Hartwig, J. F. & Zhao, H., Dec 6 2013, In: ACS Catalysis. 3, 12, p. 2856-2864 9 p.

Research output: Contribution to journal › Review article › peer-review

Orthogonal control of endogenous gene expression in mammalian cells using synthetic ligands

Liang, J., Mclachlan, M. J. & Zhao, H., May 1 2013, In: Biotechnology and bioengineering. 110, 5, p. 1419-1429 11 p.

Research output: Contribution to journal › Article › peer-review

Pathway engineering as an enabling synthetic biology tool

Eriksen, D. T., Li, S. & Zhao, H., Aug 27 2013, Synthetic Biology. Elsevier Inc., p. 43-61 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold

Shao, Z., Rao, G., Li, C., Abil, Z., Luo, Y. & Zhao, H., Nov 15 2013, In: ACS synthetic biology. 2, 11, p. 662-669 8 p.

Research output: Contribution to journal › Article › peer-review

Synthetic Biology

Zhao, H., Jan 1 2013, Elsevier Inc.

Research output: Book/Report/Conference proceeding › Book

Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing.

Sun, N. & Zhao, H., Jul 2013, In: Biotechnology and bioengineering. 110, 7, p. 1811-1821 11 p.

Research output: Contribution to journal › Review article › peer-review

2014

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