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• 2011

  A diverse family of novel peptide toxins from an unusual cone snail, Conus californicus

  Gilly, W. F., Richmond, T. A., Duda, T. F., Elliger, C., Lebaric, Z., Schulz, J., Bingham, J. P. & Sweedler, J. V., Jan 2011, In: Journal of Experimental Biology. 214, 1, p. 147-161 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Conus Snail
  • Conus
  • seed cones
  • snail
  • toxin

• A novel pyridoxal 5'-phosphate-dependent amino acid racemase in the aplysia californica central nervous system

  Wang, L., Ota, N., Romanova, E. V. & Sweedler, J. V., Apr 15 2011, In: Journal of Biological Chemistry. 286, 15, p. 13765-13774 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Isomerases
  • aspartate racemase
  • D-Aspartic Acid
  • Aplysia
  • Pyridoxal Phosphate

• Chronic morphine alters the presynaptic protein profile: Identification of novel molecular targets using proteomics and network analysis

  Abul-Husn, N. S., Annangudi, S. P., Ma'ayan, A., Ramos-Ortolaza, D. L., Stockton, S. D., Gomes, I., Sweedler, J. V. & Devi, L. A., Oct 17 2011, In: PloS one. 6, 10, e25535.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • morphine
  • Electric network analysis
  • protein composition
  • Morphine

• Collection of peptides released from single neurons with particle-embedded monolithic capillaries followed by detection with matrix-assisted laser desorption/ionization mass spectrometry

  Fan, Y., Rubakhin, S. & Sweedler, J. V., Dec 15 2011, In: Analytical Chemistry. 83, 24, p. 9557-9563 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Desorption
  • Pyrrolidinones
  • ethylenediamine

• Comparison of tandem mass spectrometry search methods to identify neuropeptides

  Akhtar, M. N., Southey, B. R., Porter, K. I., Sweedler, J. V. & Rodriguez-Zas, S. L., 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 982-984 3 p. 6112530. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Neuropeptides
  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Peptides
  • Amino acids

• Direct cellular peptidomics of hypothalamic neurons

  Mitchell, J. W., Atkins, N., Sweedler, J. V. & Gillette, M. U., Oct 2011, In: Frontiers in Neuroendocrinology. 32, 4, p. 377-386 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neurons
  • Peptides
  • Cell signaling
  • Supraoptic Nucleus
  • Suprachiasmatic Nucleus

• Distinguishing endogenous d-amino acid-containing neuropeptides in individual neurons using tandem mass spectrometry

  Bai, L., Romanova, E. V. & Sweedler, J. V., Apr 1 2011, In: Analytical Chemistry. 83, 7, p. 2794-2800 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Neuropeptides
  • Neurons
  • Amino Acids
  • Peptides

• Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history

  Elliger, C. A., Richmond, T. A., Lebaric, Z. N., Pierce, N. T., Sweedler, J. V. & Gilly, W. F., Feb 2011, In: Toxicon. 57, 2, p. 311-322 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Conotoxins
  • History
  • Peptides
  • Molluscs
  • Gene encoding

• Integration of sequence and functional information to identify and annotate neuropeptides in the pig genome

  Porter, K. I., Southey, B. R., Akhtar, M. N., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 988-990 3 p. 6112532. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Neuropeptides
  • Genes
  • Swine
  • Genome
  • proenkephalin

• MALDI mass spectrometry imaging of neuronal cell cultures

  Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 2011, In: Journal of the American Society for Mass Spectrometry. 22, 5, p. 828-836 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell culture
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Aplysia
  • Mass Spectrometry

• Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry

  Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Sep 1 2011, In: Analytical chemistry. 83, 17, p. 6810-6817 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Mass spectrometry
  • Neurons
  • Metabolites

• Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord

  Miller, L. K., Hou, X., Rodriguiz, R. M., Gagnidze, K., Sweedler, J. V., Wetsel, W. C. & Devi, L. A., Dec 2011, In: Journal of Neurochemistry. 119, 5, p. 1074-1085 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin-Converting Enzymes
  • Morphine
  • Spinal Cord
  • Peptides
  • Neuropeptides

• Model of ion intensity from tandem mass spectra for improved peptide identification and simulation

  Fazal, Z., Southey, B. R., Sadeque, A., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 994-996 3 p. 6112534. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Peptides
  • Ions
  • Mass spectrometry
  • Protons
  • Tandem Mass Spectrometry

• Molecular organization of drosophila neuroendocrine cells by dimmed

  Park, D., Hadžić, T., Yin, P., Rusch, J., Abruzzi, K., Rosbash, M., Skeath, J. B., Panda, S., Sweedler, J. V. & Taghert, P. H., Sep 27 2011, In: Current Biology. 21, 18, p. 1515-1524 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroendocrine Cells
  • Drosophila
  • Assays
  • Secretory Vesicles
  • cytochrome b561

• Neuropeptidomics: Mass spectrometry-based qualitative and quantitative analysis

  Yin, P., Hou, X., Romanova, E. V. & Sweedler, J. V., 2011, Neuropeptides: Methods and Protocols. Merighi, A. (ed.). p. 223-236 14 p. (Methods in Molecular Biology; vol. 789).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neuropeptides
  • Mass Spectrometry
  • Liquid Chromatography
  • Peptides
  • Protein Precursors

• Neuropeptidomics

  Sweedler, J. V., Xie, F. & Bora, A., Sep 23 2011, Protein and Peptide Mass Spectrometry in Drug Discovery. John Wiley and Sons, p. 393-433 41 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Neuropeptidomics of the mammalian brain

  Xie, F., Romanova, E. V. & Sweedler, J. V., Jun 3 2011, Neuroproteomics. Li, K. W. (ed.). p. 229-242 14 p. (Neuromethods; vol. 57).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Brain
  • Mass spectrometry
  • Peptides
  • Mass Spectrometry
  • Liquid chromatography

• Probing the production of amidated peptides following genetic and dietary copper manipulations

  Yin, P., Bousquet-Moore, D., Annangudi, S. P., Southey, B. R., Mains, R. E., Eipper, B. A. & Sweedler, J. V., Dec 16 2011, In: PloS one. 6, 12, e28679.

  Research output: Contribution to journal › Article › peer-review

  • peptidylglycine monooxygenase
  • Mixed Function Oxygenases
  • Copper
  • copper
  • peptides

• Profiling metabolites and peptides in single cells

  Rubakhin, S. S., Romanova, E. V., Nemes, P. & Sweedler, J. V., Apr 2011, In: Nature Methods. 8, 4, p. S20-S29

  Research output: Contribution to journal › Article › peer-review

  • Metabolites
  • Developmental Biology
  • Cytology
  • Stem cells
  • Microanalysis

• Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry

  Amaya, K. R., Sweedler, J. V. & Clayton, D. F., Aug 2011, In: Journal of Neurochemistry. 118, 4, p. 499-511 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary Ion Mass Spectrometry
  • Secondary ion mass spectrometry
  • Finches
  • Equidae
  • Music

• Stretched tissue mounting for MALDI mass spectrometry imaging

  Tucker, K. R., Lanni, E. J., Serebryannyy, L. A., Rubakhin, S. & Sweedler, J. V., Dec 1 2011, In: Analytical Chemistry. 83, 23, p. 9181-9185 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Desorption
  • Mountings
  • Tissue

• The enzyme function initiative

  Gerlt, J. A., Allen, K. N., Almo, S. C., Armstrong, R. N., Babbitt, P. C., Cronan, J. E., Dunaway-Mariano, D., Imker, H. J., Jacobson, M. P., Minor, W., Poulter, C. D., Raushel, F. M., Sali, A., Shoichet, B. K. & Sweedler, J. V., Nov 22 2011, In: Biochemistry. 50, 46, p. 9950-9962 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Enzymes
  • Microbiology
  • Genes
  • Amidohydrolases
  • Genome

• The mechanical sensitivity of vesicle dynamics in in vivo and in vitro neurons

  Ahmed, W. W., Li, T. C., Rubakhin, S., Chiba, A., Sweedler, J. V. & Saif, M. T. A., Nov 23 2011, Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011. p. 436-439 4 p. (Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011; vol. 3).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Neurons
  • Cones
  • Imaging techniques

• The modified-bead stretched sample method: Development and application to MALDI-MS imaging of protein localization in the spinal cord

  Tucker, K. R., Serebryannyy, L. A., Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., 2011, In: Chemical Science. 2, 4, p. 785-795 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Desorption
  • Imaging techniques
  • Lasers

• The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary

  Aujla, P. K., Bora, A., Monahan, P., Sweedler, J. V. & Raetzman, L. T., May 1 2011, In: Developmental Biology. 353, 1, p. 61-71 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Arginine Vasopressin
  • Neuropeptides
  • Axons
  • Supraoptic Nucleus
  • Paraventricular Hypothalamic Nucleus

• Using microfluidics and mass spectrometry to study peptide release in neurons

  Croushore, C. A., Lee, C. Y., Zhong, M. & Sweedler, J. V., Dec 1 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. p. 858-860 3 p. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; vol. 2).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Peptides
  • Mass spectrometry
  • Microfluidics
  • Neurons
  • Neuropeptides
• 2013

  Are we virtual yet?

  Sweedler, J. V., Apr 2 2013, In: Analytical chemistry. 85, 7, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Automated method for analysis of tryptophan and tyrosine metabolites using capillary electrophoresis with native fluorescence detection

  Dailey, C. A., Garnier, N., Rubakhin, S. S. & Sweedler, J. V., Mar 2013, In: Analytical and bioanalytical chemistry. 405, 8, p. 2451-2459 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillary electrophoresis
  • Metabolites
  • Capillary Electrophoresis
  • Fluorescence
  • Tryptophan

• Buyer beware! Think twice when selecting a journal (or attending a conference)

  Sweedler, J. V., Nov 5 2013, In: Analytical chemistry. 85, 21, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Celebrating the 75th anniversary of the ACS division of analytical chemistry: A special collection of the most highly cited analytical chemistry papers published between 1938 and 2012

  Larive, C. K. & Sweedler, J. V., May 7 2013, In: Analytical chemistry. 85, 9, p. 4201-4202 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Characterization of GdFFD, a D-amino acid-containing neuropeptide that functions as an extrinsic modulator of the Aplysia feeding circuit

  Bai, L., Livnat, I., Romanova, E. V., Alexeeva, V., Yau, P. M., Vilim, F. S., Weiss, K. R., Jing, J. & Sweedler, J. V., Nov 15 2013, In: Journal of Biological Chemistry. 288, 46, p. 32837-32851 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Aplysia
  • Neuropeptides
  • Modulators
  • Amino Acids
  • Peptides

• Combining small-volume metabolomic and transcriptomic approaches for assessing brain chemistry

  Knolhoff, A. M., Nautiyal, K. M., Nemes, P., Kalachikov, S., Morozova, I., Silver, R. & Sweedler, J. V., Mar 19 2013, In: Analytical Chemistry. 85, 6, p. 3136-3143 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolites
  • Capillary electrophoresis
  • Mass spectrometry
  • Brain

• Correlated imaging-a grand challenge in chemical analysis

  Masyuko, R., Lanni, E. J., Sweedler, J. V. & Bohn, P. W., Apr 7 2013, In: Analyst. 138, 7, p. 1924-1939 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • chemical analysis
  • Imaging techniques
  • Chemical analysis
  • chemical
  • experiment

• Details matter, and so do statistics

  Sweedler, J. V., Jun 4 2013, In: Analytical chemistry. 85, 11, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Discovery of new enzymes and metabolic pathways by using structure and genome context

  Zhao, S., Kumar, R., Sakai, A., Vetting, M. W., Wood, B. M. K., Brown, S., Bonanno, J. B., Hillerich, B. S., Seidel, R. D., Babbitt, P. C., Almo, S. C., Sweedler, J. V., Gerlt, J. A., Cronan, J. E. & Jacobson, M. P., 2013, In: Nature. 502, 7473, p. 698-702 5 p.

  Research output: Contribution to journal › Article › peer-review

  • stachydrine
  • Metabolic Networks and Pathways
  • Substrate Specificity
  • Multigene Family
  • Genome

• Laminar stream of detergents for subcellular neurite damage in a microfluidic device: A simple tool for the study of neuroregeneration

  Lee, C. Y., Romanova, E. V. & Sweedler, J. V., Jun 2013, In: Journal of Neural Engineering. 10, 3, 036020.

  Research output: Contribution to journal › Article › peer-review

  • Lab-On-A-Chip Devices
  • Detergents
  • Neurites
  • Microfluidics
  • Neurons

• Meet our second advisory board, the analytical chemistry features panel

  Sweedler, J. V., Aug 20 2013, In: Analytical chemistry. 85, 16, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Meet the Analytical Chemistry editorial advisory board

  Sweedler, J. V., Feb 5 2013, In: Analytical chemistry. 85, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Microfluidic systems for studying neurotransmitters and neurotransmission

  Croushore, C. A. & Sweedler, J. V., May 7 2013, In: Lab on a chip. 13, 9, p. 1666-1676 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Microfluidics
  • Molecules
  • Synaptic Transmission
  • Neurotransmitter Agents
  • Cell signaling

• Multifactorial understanding of ion abundance in tandem mass spectrometry experiments

  Fazal, Z., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., 2013, In: Journal of Proteomics and Bioinformatics. 6, 2, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Ions
  • Peptides
  • Experiments

• New Mass Spectrometric Approaches for Uncovering Neuropeptides

  Hou, X. & Sweedler, J. V., Aug 29 2013, Handbook of Biologically Active Peptides. Elsevier Inc., p. 1749-1756 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Pittcon: Still vibrant after more than 60 years

  Sweedler, J. V., Mar 5 2013, In: Analytical chemistry. 85, 5, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Progress toward single cell metabolomics

  Rubakhin, S. S., Lanni, E. J. & Sweedler, J. V., Feb 2013, In: Current Opinion in Biotechnology. 24, 1, p. 95-104 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolomics
  • Metabolites
  • Molecules
  • Mass spectrometry
  • Microfluidics

• Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry

  Nemes, P., Rubakhin, S. S., Aerts, J. T. & Sweedler, J. V., Apr 2013, In: Nature Protocols. 8, 4, p. 783-799 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Metabolomics
  • Electrospray Ionization Mass Spectrometry
  • Capillary Electrophoresis

• Quantitation of endogenous peptides using mass spectrometry based methods

  Romanova, E. V., Dowd, S. E. & Sweedler, J. V., Oct 2013, In: Current Opinion in Chemical Biology. 17, 5, p. 801-808 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Mass spectrometry
  • Mass Spectrometry
  • Peptides
  • Molecular interactions
  • Industrial Development

• Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus

  Lee, J. E., Zamdborg, L., Southey, B. R., Atkins, N., Mitchell, J. W., Li, M., Gillette, M. U., Kelleher, N. L. & Sweedler, J. V., Feb 1 2013, In: Journal of Proteome Research. 12, 2, p. 585-593 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Suprachiasmatic Nucleus
  • Rats
  • Peptides
  • Mammals
  • Optic Chiasm

• Quantitative reflection imaging of fixed aplysia californica pedal ganglion neurons on nanostructured plasmonic crystals

  Le, A. P., Kang, S., Thompson, L. B., Rubakhin, S. S., Sweedler, J. V., Rogers, J. A. & Nuzzo, R. G., Nov 4 2013, In: Journal of Physical Chemistry B. 117, 42, p. 13069-13081 13 p.

  Research output: Contribution to journal › Article › peer-review

  • pedals
  • Surface plasmon resonance
  • Plasmonics
  • neurons
  • Crystals

• Reflections from my first year

  Sweedler, J. V., Jan 2 2013, In: Analytical chemistry. 85, 1, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Signals from the Brainstem Sleep/Wake Centers Regulate Behavioral Timing via the Circadian Clock

  Abbott, S. M., Arnold, J. M., Chang, Q., Miao, H., Ota, N., Cecala, C., Gold, P. E., Sweedler, J. V. & Gillette, M. U., Aug 12 2013, In: PloS one. 8, 8, e70481.

  Research output: Contribution to journal › Article › peer-review

  • Suprachiasmatic Nucleus
  • Circadian Clocks
  • brain stem
  • circadian clocks
  • sleep

• Stimulation and release from neurons via a dual capillary collection device interfaced to mass spectrometry

  Fan, Y., Lee, C. Y., Rubakhin, S. S. & Sweedler, J. V., Nov 7 2013, In: Analyst. 138, 21, p. 6337-6346 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuropeptides
  • Peptides
  • Mass spectrometry
  • Neurons
  • Mass Spectrometry