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  • Yi Lu
2016

Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase

Chauhan, S., Hosseinzadeh, P., Lu, Y. & Blackburn, N. J., Apr 19 2016, In : Biochemistry. 55, 13, p. 2008-2021 14 p.

Research output: Contribution to journalArticle

2017
2016

Effect of Outer-Sphere Side Chain Substitutions on the Fate of the trans Iron-Nitrosyl Dimer in Heme/Nonheme Engineered Myoglobins (FeBMbs): Insights into the Mechanism of Denitrifying NO Reductases

Matsumura, H., Chakraborty, S., Reed, J., Lu, Y. & Moënne-Loccoz, P., Apr 12 2016, In : Biochemistry. 55, 14, p. 2091-2099 9 p.

Research output: Contribution to journalArticle

2017

“Dipstick” colorimetric detection of metal ions based on immobilization of DNAzyme and gold nanoparticles onto a lateral flow device

Mazumdar, D., Lan, T. & Lu, Y., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 389-406 18 p. (Methods in Molecular Biology; vol. 1571).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

S-Click Reaction for Isotropic Orientation of Oxidases on Electrodes to Promote Electron Transfer at Low Potentials

Xia, L., Han, M. J., Zhou, L., Huang, A., Yang, Z., Wang, T., Li, F., Yu, L., Tian, C., Zang, Z., Yang, Q. Z., Liu, C., Hong, W., Lu, Y., Alfonta, L. & Wang, J., Nov 11 2019, In : Angewandte Chemie - International Edition. 58, 46, p. 16480-16484 5 p.

Research output: Contribution to journalArticle

2018

Translating molecular detections into a simple temperature test using a target-responsive smart thermometer

Zhang, J., Xing, H. & Lu, Y., Jan 1 2018, In : Chemical Science. 9, 16, p. 3906-3910 5 p.

Research output: Contribution to journalArticle

2019

DNAzymes as Activity-Based Sensors for Metal Ions: Recent Applications, Demonstrated Advantages, Current Challenges, and Future Directions

Lake, R. J., Yang, Z., Zhang, J. J. & Lu, Y., Dec 17 2019, In : Accounts of chemical research. 52, 12, p. 3275-3286 12 p.

Research output: Contribution to journalArticle

Understanding and Modulating Metalloenzymes with Unnatural Amino Acids, Non-Native Metal Ions, and Non-Native Metallocofactors

Mirts, E. N., Bhagi-Damodaran, A. & Lu, Y., Apr 16 2019, In : Accounts of chemical research. 52, 4, p. 935-944 10 p.

Research output: Contribution to journalArticle

2018

O2 Reduction by Biosynthetic Models of Cytochrome c Oxidase: Insights into Role of Proton Transfer Residues from Perturbed Active Sites Models of CcO

Mukherjee, S., Mukherjee, M., Mukherjee, A., Bhagi-Damodaran, A., Lu, Y. & Dey, A., Sep 7 2018, In : ACS Catalysis. 8, 9, p. 8915-8924 10 p.

Research output: Contribution to journalArticle

2019

Functional DNA Molecules Enable Selective and Stimuli-Responsive Nanoparticles for Biomedical Applications

Li, L., Xing, H., Zhang, J. & Lu, Y., Sep 17 2019, In : Accounts of chemical research. 52, 9, p. 2415-2426 12 p.

Research output: Contribution to journalArticle

2016

Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities

Bhagi-Damodaran, A., Petrik, I. & Lu, Y., Oct 1 2016, In : Israel Journal of Chemistry. 56, 9-10, p. 773-790 18 p.

Research output: Contribution to journalReview article

2019

Bioapplications of DNA nanotechnology at the solid-liquid interface

Wang, W., Yu, S., Huang, S., Bi, S., Han, H., Zhang, J. R., Lu, Y. & Zhu, J. J., Sep 21 2019, In : Chemical Society Reviews. 48, 18, p. 4892-4920 29 p.

Research output: Contribution to journalReview article

2016

Integration of Solution-Based Assays onto Lateral Flow Device for One-Step Quantitative Point-of-Care Diagnostics Using Personal Glucose Meter

Zhang, J., Shen, Z., Xiang, Y. & Lu, Y., Sep 23 2016, In : ACS Sensors. 1, 9, p. 1091-1096 6 p.

Research output: Contribution to journalArticle

Size-dependent modulation of graphene oxide-aptamer interactions for an amplified fluorescence-based detection of aflatoxin B1 with a tunable dynamic range

Zhang, J., Li, Z., Zhao, S. & Lu, Y., Jul 7 2016, In : Analyst. 141, 13, p. 4029-4034 6 p.

Research output: Contribution to journalArticle

2018

Evidence of a General Acid-Base Catalysis Mechanism in the 8-17 DNAzyme

Cepeda-Plaza, M., McGhee, C. E. & Lu, Y., Mar 6 2018, In : Biochemistry. 57, 9, p. 1517-1522 6 p.

Research output: Contribution to journalArticle

2016

Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions

Hosseinzadeh, P., Mirts, E. N., Pfister, T. D., Gao, Y. G., Mayne, C., Robinson, H., Tajkhorshid, E. & Lu, Y., Mar 15 2016, In : Biochemistry. 55, 10, p. 1494-1502 9 p.

Research output: Contribution to journalArticle

2019

Y-Shaped Backbone-Rigidified Triangular DNA Scaffold-Directed Stepwise Movement of a DNAzyme Walker for Sensitive MicroRNA Imaging within Living Cells

Xue, C., Zhang, S., Li, C., Yu, X., Ouyang, C., Lu, Y. & Wu, Z. S., Dec 17 2019, In : Analytical chemistry. 91, 24, p. 15678-15685 8 p.

Research output: Contribution to journalArticle

2017

Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases

Bhagi-Damodaran, A., Michael, M. A., Zhu, Q., Reed, J., Sandoval, B. A., Mirts, E. N., Chakraborty, S., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Mar 1 2017, In : Nature Chemistry. 9, 3, p. 257-263 7 p.

Research output: Contribution to journalArticle

2016

Reversible S-nitrosylation in an engineered azurin

Tian, S., Liu, J., Cowley, R. E., Hosseinzadeh, P., Marshall, N. M., Yu, Y., Robinson, H., Nilges, M. J., Blackburn, N. J., Solomon, E. I. & Lu, Y., Jul 1 2016, In : Nature Chemistry. 8, 7, p. 670-677 8 p.

Research output: Contribution to journalArticle

2017

Advances in the development of aptamer drug conjugates for targeted drug delivery

Chen, K., Liu, B., Yu, B., Zhong, W., Lu, Y., Zhang, J., Liao, J., Liu, J., Pu, Y., Qiu, L., Zhang, L., Liu, H. & Tan, W., May 1 2017, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 9, 3, e1438.

Research output: Contribution to journalReview article

2018

A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme

Mirts, E. N., Petrik, I. D., Hosseinzadeh, P., Nilges, M. J. & Lu, Y., Sep 14 2018, In : Science. 361, 6407, p. 1098-1101 4 p.

Research output: Contribution to journalArticle

2017

Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand

Xing, H., Bai, Y., Bai, Y., Tan, L. H., Tao, J., Pedretti, B., Vincil, G. A., Lu, Y. & Zimmerman, S. C., Mar 15 2017, In : Journal of the American Chemical Society. 139, 10, p. 3623-3626 4 p.

Research output: Contribution to journalArticle

2016

Spectroscopic and Crystallographic Evidence for the Role of a Water-Containing H-Bond Network in Oxidase Activity of an Engineered Myoglobin

Petrik, I. D., Davydov, R., Ross, M., Zhao, X., Hoffman, B. & Lu, Y., Feb 3 2016, In : Journal of the American Chemical Society. 138, 4, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

2018

Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells

Zhao, J., Gao, J., Xue, W., Di, Z., Xing, H., Lu, Y. & Li, L., Jan 17 2018, In : Journal of the American Chemical Society. 140, 2, p. 578-581 4 p.

Research output: Contribution to journalArticle

2017

DNA Aptamer-Based Activatable Probes for Photoacoustic Imaging in Living Mice

Zhang, J., Smaga, L. P., Satyavolu, N. S. R., Chan, J. & Lu, Y., Dec 6 2017, In : Journal of the American Chemical Society. 139, 48, p. 17225-17228 4 p.

Research output: Contribution to journalArticle

Recent advances in DNAzyme-based gene silencing

Fan, H., Zhang, X. & Lu, Y., May 1 2017, In : Science China Chemistry. 60, 5, p. 591-601 11 p.

Research output: Contribution to journalReview article

Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism

Reed, J. H., Shi, Y., Zhu, Q., Chakraborty, S., Mirts, E. N., Petrik, I. D., Bhagi-Damodaran, A., Ross, M., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Sep 6 2017, In : Journal of the American Chemical Society. 139, 35, p. 12209-12218 10 p.

Research output: Contribution to journalArticle

2016

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

Zhang, J. J., Cheng, F. F., Li, J. J., Zhu, J. J. & Lu, Y., Jun 1 2016, In : Nano Today. 11, 3, p. 309-329 21 p.

Research output: Contribution to journalReview article

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

Hwang, K., Hosseinzadeh, P. & Lu, Y., 2016, In : Inorganica Chimica Acta. 452, p. 12-24 13 p.

Research output: Contribution to journalReview article

2019

Silver-Assisted Synthesis of High-Indexed Palladium Tetrahexahedral Nanoparticles and Their Morphological Variants

Satyavolu, N. S. R., Peinetti, A. S., Wang, Y., Ali, A. S., Lin, J. W. & Lu, Y., Apr 23 2019, In : Chemistry of Materials. 31, 8, p. 2923-2929 7 p.

Research output: Contribution to journalArticle

Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter

Xu, J., Qiao, X., Zhang, J., Cheng, N., Sheng, Q., Zheng, J., Cao, W., Yue, T. & Lu, Y., Apr 14 2019, In : Analytical Methods. 11, 14, p. 1849-1856 8 p.

Research output: Contribution to journalArticle

Cupredoxin engineered upconversion nanoparticles for ratiometric luminescence sensing of Cu2+

Liu, C., Yu, Y., Chen, D., Zhao, J., Yu, Y., Li, L. & Lu, Y., 2019, In : Nanoscale Advances. 1, 7, p. 2580-2585 6 p.

Research output: Contribution to journalArticle

Open Access
2016

Transforming the blood glucose meter into a general healthcare meter for in vitro diagnostics in mobile health

Lan, T., Zhang, J. & Lu, Y., May 1 2016, In : Biotechnology Advances. 34, 3, p. 331-341 11 p.

Research output: Contribution to journalReview article

2017

Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase

Bhagi-Damodaran, A., Kahle, M., Shi, Y., Zhang, Y., Ädelroth, P. & Lu, Y., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 23, p. 6622-6626 5 p.

Research output: Contribution to journalArticle

Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme–Catalytic Hairpin Assembly Probe

Wu, Z., Fan, H., Satyavolu, N. S. R., Wang, W. J., Lake, R., Jiang, J. H. & Lu, Y., Jul 17 2017, In : Angewandte Chemie - International Edition. 56, 30, p. 8721-8725 5 p.

Research output: Contribution to journalArticle

2016

Design and engineering of artificial oxygen-activating metalloenzymes

Nastri, F., Chino, M., Maglio, O., Bhagi-Damodaran, A., Lu, Y. & Lombardi, A., Sep 21 2016, In : Chemical Society Reviews. 45, 18, p. 5020-5054 35 p.

Research output: Contribution to journalReview article

2020

A photo-regulated aptamer sensor for spatiotemporally controlled monitoring of ATP in the mitochondria of living cells

Hong, S., Zhang, X., Lake, R. J., Pawel, G. T., Guo, Z., Pei, R. & Lu, Y., Jan 1 2020, In : Chemical Science. 11, 3, p. 713-720 8 p.

Research output: Contribution to journalArticle

Open Access
2016

Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics

Hosseinzadeh, P. & Lu, Y., May 1 2016, In : Biochimica et Biophysica Acta - Bioenergetics. 1857, 5, p. 557-581 25 p.

Research output: Contribution to journalArticle

2019

Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors

Hwang, K., Mou, Q., Lake, R. J., Xiong, M., Holland, B. & Lu, Y., Oct 21 2019, In : Inorganic Chemistry. 58, 20, p. 13696-13708 13 p.

Research output: Contribution to journalReview article

2017

Thiolate Spin Population of Type I Copper in Azurin Derived from33S Hyperfine Coupling

Ramirez Cohen, M., Mendelman, N., Radoul, M., Wilson, T. D., Savelieff, M. G., Zimmermann, H., Kaminker, I., Feintuch, A., Lu, Y. & Goldfarb, D., Jun 5 2017, In : Inorganic Chemistry. 56, 11, p. 6163-6174 12 p.

Research output: Contribution to journalArticle

2020

Independent control over size, valence, and elemental composition in the synthesis of DNA-nanoparticle conjugates

Bai, Y., Xing, H., Bai, Y., Tan, L. H., Hwang, K., Li, J., Lu, Y. & Zimmerman, S. C., Feb 14 2020, In : Chemical Science. 11, 6, p. 1564-1572 9 p.

Research output: Contribution to journalArticle

Open Access
2016

Multimodal Detection of a Small Molecule Target Using Stimuli-Responsive Liposome Triggered by Aptamer-Enzyme Conjugate

Xing, H., Zhang, C. L., Ruan, G., Zhang, J., Hwang, K. & Lu, Y., Feb 2 2016, In : Analytical chemistry. 88, 3, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

2019

Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications

Zhang, J. J., Lan, T. & Lu, Y., Mar 21 2019, In : Advanced Healthcare Materials. 8, 6, 1801158.

Research output: Contribution to journalReview article

2018

Insights into the Competition between K+ and Pb2+ Binding to a G-Quadruplex and Discovery of a Novel K+-Pb2+-Quadruplex Intermediate

Yu, Z., Zhou, W., Ma, G., Li, Y., Fan, L., Li, X. & Lu, Y., Oct 11 2018, In : Journal of Physical Chemistry B. 122, 40, p. 9382-9388 7 p.

Research output: Contribution to journalArticle

2017

DNAzyme sensors for detection of metal ions in the environment and imaging them in living cells

McGhee, C. E., Loh, K. Y. & Lu, Y., Jun 1 2017, In : Current Opinion in Biotechnology. 45, p. 191-201 11 p.

Research output: Contribution to journalReview article

2019
2018

A new era for electron bifurcation

Peters, J. W., Beratan, D. N., Bothner, B., Dyer, R. B., Harwood, C. S., Heiden, Z. M., Hille, R., Jones, A. K., King, P. W., Lu, Y., Lubner, C. E., Minteer, S. D., Mulder, D. W., Raugei, S., Schut, G. J., Seefeldt, L. C., Tokmina-Lukaszewska, M., Zadvornyy, O. A., Zhang, P. & Adams, M. WW., Dec 2018, In : Current Opinion in Chemical Biology. 47, p. 32-38 7 p.

Research output: Contribution to journalReview article

2020