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  • Yi Lu
2020

Independent control over size, valence, and elemental composition in the synthesis of DNA-nanoparticle conjugates

Bai, Y., Xing, H., Bai, Y., Tan, L. H., Hwang, K., Li, J., Lu, Y. & Zimmerman, S. C., Feb 14 2020, In : Chemical Science. 11, 6, p. 1564-1572 9 p.

Research output: Contribution to journalArticle

Open Access
2019

Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors

Hwang, K., Mou, Q., Lake, R. J., Xiong, M., Holland, B. & Lu, Y., Oct 21 2019, In : Inorganic Chemistry. 58, 20, p. 13696-13708 13 p.

Research output: Contribution to journalReview article

2017

Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme–Catalytic Hairpin Assembly Probe

Wu, Z., Fan, H., Satyavolu, N. S. R., Wang, W. J., Lake, R., Jiang, J. H. & Lu, Y., Jul 17 2017, In : Angewandte Chemie - International Edition. 56, 30, p. 8721-8725 5 p.

Research output: Contribution to journalArticle

2019

Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter

Xu, J., Qiao, X., Zhang, J., Cheng, N., Sheng, Q., Zheng, J., Cao, W., Yue, T. & Lu, Y., Apr 14 2019, In : Analytical Methods. 11, 14, p. 1849-1856 8 p.

Research output: Contribution to journalArticle

Discovery of and Insights into DNA “Codes” for Tunable Morphologies of Metal Nanoparticles

Satyavolu, N. S. R., Loh, K. Y., Tan, L. H. & Lu, Y., Jun 26 2019, In : Small. 15, 26, 1900975.

Research output: Contribution to journalReview article

Cupredoxin engineered upconversion nanoparticles for ratiometric luminescence sensing of Cu2+

Liu, C., Yu, Y., Chen, D., Zhao, J., Yu, Y., Li, L. & Lu, Y., Jan 1 2019, In : Nanoscale Advances. 1, 7, p. 2580-2585 6 p.

Research output: Contribution to journalArticle

Open Access
2016

Design of a single protein that spans the entire 2-V range of physiological redox potentials

Hosseinzadeh, P., Marshall, N. M., Chacón, K. N., Yu, Y., Nilges, M. J., New, S. Y., Tashkov, S. A., Blackburn, N. J. & Lu, Y., Jan 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 2, p. 262-267 6 p.

Research output: Contribution to journalArticle

Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities

Bhagi-Damodaran, A., Petrik, I. & Lu, Y., Oct 1 2016, In : Israel Journal of Chemistry. 56, 9-10, p. 773-790 18 p.

Research output: Contribution to journalReview article

Design of Heteronuclear Metalloenzymes

Bhagi-Damodaran, A., Hosseinzadeh, P., Mirts, E., Reed, J., Petrik, I. D. & Lu, Y., Jan 1 2016, Methods in Enzymology. Academic Press Inc., p. 501-537 37 p. (Methods in Enzymology; vol. 580).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Y-Shaped Backbone-Rigidified Triangular DNA Scaffold-Directed Stepwise Movement of a DNAzyme Walker for Sensitive MicroRNA Imaging within Living Cells

Xue, C., Zhang, S., Li, C., Yu, X., Ouyang, C., Lu, Y. & Wu, Z. S., Dec 17 2019, In : Analytical chemistry. 91, 24, p. 15678-15685 8 p.

Research output: Contribution to journalArticle

2016

A density functional theory protocol for the calculation of redox potentials of copper complexes

Yan, L., Lu, Y. & Li, X., Jan 1 2016, In : Physical Chemistry Chemical Physics. 18, 7, p. 5529-5536 8 p.

Research output: Contribution to journalArticle

2019

CHAPTER 2: Design and Engineering of Heme Enzymes with O2-dependent Catalytic Activity

Cui, C., Reed, J. H., Mirts, E. N. & Lu, Y., Jan 1 2019, Dioxygen-dependent Heme Enzymes. Ikeda-Saito, M. & Raven, E. (eds.). 13 ed. Royal Society of Chemistry, p. 37-62 26 p. (RSC Metallobiology; vol. 2019-January, no. 13).

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism

Reed, J. H., Shi, Y., Zhu, Q., Chakraborty, S., Mirts, E. N., Petrik, I. D., Bhagi-Damodaran, A., Ross, M., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Sep 6 2017, In : Journal of the American Chemical Society. 139, 35, p. 12209-12218 10 p.

Research output: Contribution to journalArticle

2016

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

Zhang, J. J., Cheng, F. F., Li, J. J., Zhu, J. J. & Lu, Y., Jun 1 2016, In : Nano Today. 11, 3, p. 309-329 21 p.

Research output: Contribution to journalReview article

2018

Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles

Yang, Z., Loh, K. Y., Chu, Y. T., Feng, R., Satyavolu, N. S. R., Xiong, M., Nakamata Huynh, S. M., Hwang, K., Li, L., Xing, H., Zhang, X., Chemla, Y. R., Gruebele, M. & Lu, Y., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17656-17665 10 p.

Research output: Contribution to journalArticle

2017

Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases

Bhagi-Damodaran, A., Michael, M. A., Zhu, Q., Reed, J., Sandoval, B. A., Mirts, E. N., Chakraborty, S., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Mar 1 2017, In : Nature Chemistry. 9, 3, p. 257-263 7 p.

Research output: Contribution to journalArticle

2016

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

Hwang, K., Hosseinzadeh, P. & Lu, Y., Jan 1 2016, In : Inorganica Chimica Acta. 452, p. 12-24 13 p.

Research output: Contribution to journalReview article

2017

DNAzyme sensors for detection of metal ions in the environment and imaging them in living cells

McGhee, C. E., Loh, K. Y. & Lu, Y., Jun 1 2017, In : Current Opinion in Biotechnology. 45, p. 191-201 11 p.

Research output: Contribution to journalReview article

Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase

Bhagi-Damodaran, A., Kahle, M., Shi, Y., Zhang, Y., Ädelroth, P. & Lu, Y., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 23, p. 6622-6626 5 p.

Research output: Contribution to journalArticle

2016

Reversible S-nitrosylation in an engineered azurin

Tian, S., Liu, J., Cowley, R. E., Hosseinzadeh, P., Marshall, N. M., Yu, Y., Robinson, H., Nilges, M. J., Blackburn, N. J., Solomon, E. I. & Lu, Y., Jul 1 2016, In : Nature Chemistry. 8, 7, p. 670-677 8 p.

Research output: Contribution to journalArticle

2018

Translating molecular detections into a simple temperature test using a target-responsive smart thermometer

Zhang, J., Xing, H. & Lu, Y., Jan 1 2018, In : Chemical Science. 9, 16, p. 3906-3910 5 p.

Research output: Contribution to journalArticle

2016

A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site

Hosseinzadeh, P., Tian, S., Marshall, N. M., Hemp, J., Mullen, T., Nilges, M. J., Gao, Y. G., Robinson, H., Stahl, D. A., Gennis, R. B. & Lu, Y., May 25 2016, In : Journal of the American Chemical Society. 138, 20, p. 6324-6327 4 p.

Research output: Contribution to journalArticle

2019

Digital-resolution detection of microRNA with singlebase selectivity by photonic resonator absorption microscopy

Canady, T. D., Li, N., Smith, L. D., Lu, Y., Kohli, M., Smith, A. M. & Cunningham, B. T., Sep 24 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 39, p. 19362-19367 6 p.

Research output: Contribution to journalArticle

Open Access
2017

“Dipstick” colorimetric detection of metal ions based on immobilization of DNAzyme and gold nanoparticles onto a lateral flow device

Mazumdar, D., Lan, T. & Lu, Y., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 389-406 18 p. (Methods in Molecular Biology; vol. 1571).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Advancing point-of-care diagnostics of metabolites through engineering semisynthetic proteins

Zhang, J. J. & Lu, Y., Apr 2019, In : Clinical Chemistry. 65, 4, p. 507-509 3 p.

Research output: Contribution to journalReview article

2017

Thiolate Spin Population of Type I Copper in Azurin Derived from33S Hyperfine Coupling

Ramirez Cohen, M., Mendelman, N., Radoul, M., Wilson, T. D., Savelieff, M. G., Zimmermann, H., Kaminker, I., Feintuch, A., Lu, Y. & Goldfarb, D., Jun 5 2017, In : Inorganic Chemistry. 56, 11, p. 6163-6174 12 p.

Research output: Contribution to journalArticle

2019
2016

Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions

Hosseinzadeh, P., Mirts, E. N., Pfister, T. D., Gao, Y. G., Mayne, C., Robinson, H., Tajkhorshid, E. & Lu, Y., Mar 15 2016, In : Biochemistry. 55, 10, p. 1494-1502 9 p.

Research output: Contribution to journalArticle

2020
2017

The "ok, molly" chemistry

Lu, Y., Jan 1 2017, In : Accounts of chemical research. 50, 3, p. 647-651 5 p.

Research output: Contribution to journalReview article

2016

Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase

Chauhan, S., Hosseinzadeh, P., Lu, Y. & Blackburn, N. J., Apr 19 2016, In : Biochemistry. 55, 13, p. 2008-2021 14 p.

Research output: Contribution to journalArticle

Multimodal Detection of a Small Molecule Target Using Stimuli-Responsive Liposome Triggered by Aptamer-Enzyme Conjugate

Xing, H., Zhang, C. L., Ruan, G., Zhang, J., Hwang, K. & Lu, Y., Feb 2 2016, In : Analytical chemistry. 88, 3, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

Design and engineering of artificial oxygen-activating metalloenzymes

Nastri, F., Chino, M., Maglio, O., Bhagi-Damodaran, A., Lu, Y. & Lombardi, A., Sep 21 2016, In : Chemical Society Reviews. 45, 18, p. 5020-5054 35 p.

Research output: Contribution to journalReview article

DNA-Mediated Morphological Control of Pd-Au Bimetallic Nanoparticles

Satyavolu, N. S. R., Tan, L. H. & Lu, Y., Dec 21 2016, In : Journal of the American Chemical Society. 138, 50, p. 16542-16548 7 p.

Research output: Contribution to journalArticle

2019

Silver-Assisted Synthesis of High-Indexed Palladium Tetrahexahedral Nanoparticles and Their Morphological Variants

Satyavolu, N. S. R., Peinetti, A. S., Wang, Y., Ali, A. S., Lin, J. W. & Lu, Y., Apr 23 2019, In : Chemistry of Materials. 31, 8, p. 2923-2929 7 p.

Research output: Contribution to journalArticle

2018

Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells

Zhao, J., Gao, J., Xue, W., Di, Z., Xing, H., Lu, Y. & Li, L., Jan 17 2018, In : Journal of the American Chemical Society. 140, 2, p. 578-581 4 p.

Research output: Contribution to journalArticle

2017

Advances in the development of aptamer drug conjugates for targeted drug delivery

Chen, K., Liu, B., Yu, B., Zhong, W., Lu, Y., Zhang, J., Liao, J., Liu, J., Pu, Y., Qiu, L., Zhang, L., Liu, H. & Tan, W., May 1 2017, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 9, 3, e1438.

Research output: Contribution to journalReview article

Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids

Yu, Y., Cui, C., Wang, J. & Lu, Y., Feb 1 2017, In : Science China Chemistry. 60, 2, p. 188-200 13 p.

Research output: Contribution to journalReview article

2018

Insights into the Competition between K+ and Pb2+ Binding to a G-Quadruplex and Discovery of a Novel K+-Pb2+-Quadruplex Intermediate

Yu, Z., Zhou, W., Ma, G., Li, Y., Fan, L., Li, X. & Lu, Y., Oct 11 2018, In : Journal of Physical Chemistry B. 122, 40, p. 9382-9388 7 p.

Research output: Contribution to journalArticle

2016

Spectroscopic and Crystallographic Evidence for the Role of a Water-Containing H-Bond Network in Oxidase Activity of an Engineered Myoglobin

Petrik, I. D., Davydov, R., Ross, M., Zhao, X., Hoffman, B. & Lu, Y., Feb 3 2016, In : Journal of the American Chemical Society. 138, 4, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

2019

DNAzyme-Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells

Xiong, M., Yang, Z., Lake, R. J., Li, J., Hong, S., Fan, H., Zhang, X. B. & Lu, Y., Jan 1 2019, (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Contribution to journalArticle

2018

O 2 Reduction by Biosynthetic Models of Cytochrome c Oxidase: Insights into Role of Proton Transfer Residues from Perturbed Active Sites Models of CcO

Mukherjee, S., Mukherjee, M., Mukherjee, A., Bhagi-Damodaran, A., Lu, Y. & Dey, A., Sep 7 2018, In : ACS Catalysis. 8, 9, p. 8915-8924 10 p.

Research output: Contribution to journalArticle

Sequence-specific control of inorganic nanomaterials morphologies by biomolecules

Wang, Y., Reddy Satyavolu, N. S. & Lu, Y., Nov 2018, In : Current Opinion in Colloid and Interface Science. 38, p. 158-169 12 p.

Research output: Contribution to journalReview article

2019

A NIR Light Gated DNA Nanodevice for Spatiotemporally Controlled Imaging of MicroRNA in Cells and Animals

Zhao, J., Chu, H., Zhao, Y., Lu, Y. & Li, L., May 1 2019, In : Journal of the American Chemical Society. 141, 17, p. 7056-7062 7 p.

Research output: Contribution to journalArticle

2016

Integration of Solution-Based Assays onto Lateral Flow Device for One-Step Quantitative Point-of-Care Diagnostics Using Personal Glucose Meter

Zhang, J., Shen, Z., Xiang, Y. & Lu, Y., Sep 23 2016, In : ACS Sensors. 1, 9, p. 1091-1096 6 p.

Research output: Contribution to journalArticle

2017

Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand

Xing, H., Bai, Y., Bai, Y., Tan, L. H., Tao, J., Pedretti, B., Vincil, G. A., Lu, Y. & Zimmerman, S. C., Mar 15 2017, In : Journal of the American Chemical Society. 139, 10, p. 3623-3626 4 p.

Research output: Contribution to journalArticle

2019

Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications

Zhang, J. J., Lan, T. & Lu, Y., Mar 21 2019, In : Advanced Healthcare Materials. 8, 6, 1801158.

Research output: Contribution to journalReview article

2016

A Highly Efficient Single-Chain Metal-Organic Nanoparticle Catalyst for Alkyne-Azide "click" Reactions in Water and in Cells

Bai, Y., Feng, X., Xing, H., Xu, Y., Kim, B. K., Baig, N., Zhou, T., Gewirth, A. A., Lu, Y., Oldfield, E. & Zimmerman, S. C., Sep 7 2016, In : Journal of the American Chemical Society. 138, 35, p. 11077-11080 4 p.

Research output: Contribution to journalArticle

2017

Effect of circular permutation on the structure and function of type 1 blue copper center in azurin

Yu, Y., Petrik, I. D., Chacón, K. N., Hosseinzadeh, P., Chen, H., Blackburn, N. J. & Lu, Y., Feb 1 2017, In : Protein Science. 26, 2, p. 218-226 9 p.

Research output: Contribution to journalArticle

2018

A new era for electron bifurcation

Peters, J. W., Beratan, D. N., Bothner, B., Dyer, R. B., Harwood, C. S., Heiden, Z. M., Hille, R., Jones, A. K., King, P. W., Lu, Y., Lubner, C. E., Minteer, S. D., Mulder, D. W., Raugei, S., Schut, G. J., Seefeldt, L. C., Tokmina-Lukaszewska, M., Zadvornyy, O. A., Zhang, P. & Adams, M. WW., Dec 2018, In : Current Opinion in Chemical Biology. 47, p. 32-38 7 p.

Research output: Contribution to journalReview article