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  • Huimin Zhao
2016

ACS Catalysis and the Scope of Papers Sought in Three Catalysis Subdisciplines: Biocatalysis and Enzymology, Molecular Catalysis for Organic Synthesis, and Heterogeneous Photocatalysis

Chang, S., Fornasiero, P., Gunnoe, T. B., Jones, C. W., Linic, S., Ooi, T., Williams, R. M. & Zhao, H., Jul 1 2016, In : ACS Catalysis. 6, 7, p. 4782-4785 4 p.

Research output: Contribution to journalReview article

2017

A plug-and-play pathway refactoring workflow for natural product research in Escherichia coli and Saccharomyces cerevisiae

Ren, H., Hu, P. & Zhao, H., Aug 2017, In : Biotechnology and bioengineering. 114, 8, p. 1847-1854 8 p.

Research output: Contribution to journalArticle

2018

Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis

Litman, Z. C., Wang, Y., Zhao, H. & Hartwig, J. F., Aug 16 2018, In : Nature. 560, 7718, p. 355-359 5 p.

Research output: Contribution to journalLetter

2016

New tools for reconstruction and heterologous expression of natural product biosynthetic gene clusters

Luo, Y., Enghiad, B. & Zhao, H., Feb 2016, In : Natural Product Reports. 33, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

2019

An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine

Yin, J., Wei, Y., Liu, D., Hu, Y., Lu, Q., Lui Ang, E., Zhao, H. & Zhang, Y., Jan 1 2019, In : Journal of Biological Chemistry. 294, 43, p. 15662-15671 10 p.

Research output: Contribution to journalArticle

2020

Computational Tools for Discovering and Engineering Natural Product Biosynthetic Pathways

Ren, H., Shi, C. & Zhao, H., Jan 24 2020, In : iScience. 23, 1, 100795.

Research output: Contribution to journalReview article

Open Access
2016

Editorial: Synthetic biology and bioinformatics

Medema, M. H. & Zhao, H., Aug 2016, In : Natural Product Reports. 33, 8, p. 913-914 2 p.

Research output: Contribution to journalEditorial

2019

A gene cluster for taurine sulfur assimilation in an anaerobic human gut bacterium

Xing, M., Wei, Y., Hua, G., Li, M., Nanjaraj Urs, A. N., Wang, F., Hu, Y., Zhai, W., Liu, Y., Ang, E. L., Zhao, H. & Zhang, Y., Aug 15 2019, In : Biochemical Journal. 476, 15, p. 2271-2279 9 p.

Research output: Contribution to journalArticle

2016

Accelerated genome engineering through multiplexing

Bao, Z., Cobb, R. E. & Zhao, H., Jan 1 2016, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 8, 1, p. 5-21 17 p.

Research output: Contribution to journalReview article

2019

Author Correction: Building a global alliance of biofoundries (Nature Communications, (2019), 10, 1, (2040), 10.1038/s41467-019-10079-2)

Hillson, N., Caddick, M., Cai, Y., Carrasco, J. A., Chang, M. W., Curach, N. C., Bell, D. J., Feuvre, R. L., Friedman, D. C., Fu, X., Gold, N. D., Herrgård, M. J., Holowko, M. B., Johnson, J. R., Johnson, R. A., Keasling, J. D., Kitney, R. I., Kondo, A., Liu, C., Martin, V. J. J. & 16 others, Menolascina, F., Ogino, C., Patron, N. J., Pavan, M., Poh, C. L., Pretorius, I. S., Rosser, S. J., Scrutton, N. S., Storch, M., Tekotte, H., Travnik, E., Vickers, C. E., Yew, W. S., Yuan, Y., Zhao, H. & Freemont, P. S., Dec 1 2019, In : Nature communications. 10, 1, 3132.

Research output: Contribution to journalComment/debate

Open Access
2018

Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole

Liu, D., Wei, Y., Liu, X., Zhou, Y., Jiang, L., Yin, J., Wang, F., Hu, Y., Nanjaraj Urs, A. N., Liu, Y., Ang, E. L., Zhao, S., Zhao, H. & Zhang, Y., Dec 1 2018, In : Nature communications. 9, 1, 4224.

Research output: Contribution to journalArticle

Recent developments in the application of P450 based biocatalysts

Wei, Y., Ang, E. L. & Zhao, H., Apr 2018, In : Current Opinion in Chemical Biology. 43, p. 1-7 7 p.

Research output: Contribution to journalReview article

2019

Development of a CRISPR/Cas9 system for high efficiency multiplexed gene deletion in Rhodosporidium toruloides

Schultz, J. C., Cao, M. & Zhao, H., Aug 2019, In : Biotechnology and bioengineering. 116, 8, p. 2103-2109 7 p.

Research output: Contribution to journalArticle

2017

Combining Rh-Catalyzed Diazocoupling and Enzymatic Reduction to Efficiently Synthesize Enantioenriched 2-Substituted Succinate Derivatives

Wang, Y., Bartlett, M. J., Denard, C. A., Hartwig, J. F. & Zhao, H., Apr 7 2017, In : ACS Catalysis. 7, 4, p. 2548-2552 5 p.

Research output: Contribution to journalArticle

2016

Engineered minicellulosomes for consolidated bioprocessing

Liang, Y., Ang, E. L. & Zhao, H., Jul 11 2016, Handbook of Carbohydrate-Modifying Biocatalysts. Pan Stanford Publishing Pte. Ltd., Vol. 2. p. 965-992 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Twin-primer non-enzymatic DNA assembly: An efficient and accurate multi-part DNA assembly method

Liang, J., Liu, Z., Low, X. Z., Ang, E. L. & Zhao, H., Jun 1 2017, In : Nucleic acids research. 45, 11, p. e94

Research output: Contribution to journalArticle

2019

Identification and Characterization of Citrus Peel Uronic Acid Oxidase

Wei, Y., Tan, Y. L., Ang, E. L. & Zhao, H., Jan 1 2019, (Accepted/In press) In : ChemBioChem.

Research output: Contribution to journalArticle

2017

Discovery of a Phosphonoacetic Acid Derived Natural Product by Pathway Refactoring

Freestone, T. S., Ju, K. S., Wang, B. & Zhao, H., Feb 17 2017, In : ACS synthetic biology. 6, 2, p. 217-223 7 p.

Research output: Contribution to journalArticle

2016

Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate

Sun, H., Yeo, W. L., Lim, Y. H., Chew, X., Smith, D. J., Xue, B., Chan, K. P., Robinson, R. C., Robins, E. G., Zhao, H. & Ang, E. L., Jan 1 2016, In : Angewandte Chemie - International Edition. 55, 46, p. 14277-14280 4 p.

Research output: Contribution to journalArticle

2017

A New Era of Genome Integration - Simply Cut and Paste!

Liu, Z., Liang, Y., Ang, E. L. & Zhao, H., Apr 21 2017, In : ACS synthetic biology. 6, 4, p. 601-609 9 p.

Research output: Contribution to journalReview article

Inducible Control of mRNA Transport Using Reprogrammable RNA-Binding Proteins

Abil, Z., Gumy, L. F., Zhao, H. & Hoogenraad, C. C., Jun 16 2017, In : ACS synthetic biology. 6, 6, p. 950-956 7 p.

Research output: Contribution to journalArticle

2019

A continuing career in biocatalysis: Frances H. Arnold

Fasan, R., Jennifer Kan, S. B. & Zhao, H., Nov 1 2019, In : ACS Catalysis. 9, 11, p. 9775-9788 14 p.

Research output: Contribution to journalArticle

2018

A coupled chlorinase-fluorinase system with a high efficiency of trans -halogenation and a shared substrate tolerance

Sun, H., Zhao, H. & Ang, E. L., Jan 1 2018, In : Chemical Communications. 54, 68, p. 9458-9461 4 p.

Research output: Contribution to journalArticle

2016

CRISPR/Cas9 mediated targeted mutagenesis of the fast growing cyanobacterium Synechococcus elongatus UTEX 2973

Wendt, K. E., Ungerer, J., Cobb, R. E., Zhao, H. & Pakrasi, H. B., Jun 23 2016, In : Microbial cell factories. 15, 1, 115.

Research output: Contribution to journalArticle

2020

Biosynthetic engineering of the antifungal, anti-MRSA auroramycin

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Ching, K. C., Tsai, D. J., Jhang, Y. W., Lauderdale, T. L., Shia, K. S., Zhao, H., Ang, E. L., Zhang, M. M., Lim, Y. H. & Wong, F. T., Jan 6 2020, In : Microbial cell factories. 19, 1, 3.

Research output: Contribution to journalArticle

Open Access
2019

Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Lim, Y. H., Hoon, S., Zhao, H., Zhang, M. M. & Wong, F. T., Jan 1 2019, In : Biotechnology and bioengineering. 116, 9, p. 2330-2338 9 p.

Research output: Contribution to journalArticle

2018

Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface

Limsakul, P., Peng, Q., Wu, Y., Allen, M. E., Liang, J., Remacle, A. G., Lopez, T., Ge, X., Kay, B. K., Zhao, H., Strongin, A. Y., Yang, X. L., Lu, S. & Wang, Y., Apr 19 2018, In : Cell chemical biology. 25, 4, p. 370-379.e4

Research output: Contribution to journalArticle

2020

Integrating biocatalysis with chemocatalysis for selective transformations

Huang, X., Cao, M. & Zhao, H., Apr 2020, In : Current Opinion in Chemical Biology. 55, p. 161-170 10 p.

Research output: Contribution to journalReview article

2018

Rapid Screening of Lanthipeptide Analogs via In-Colony Removal of Leader Peptides in Escherichia coli

Si, T., Tian, Q., Min, Y., Zhang, L., Sweedler, J. V., Van Der Donk, W. A. & Zhao, H., Sep 26 2018, In : Journal of the American Chemical Society. 140, 38, p. 11884-11888 5 p.

Research output: Contribution to journalArticle

Pathway design, engineering, and optimization

Garcia-Ruiz, E., HamediRad, M. & Zhao, H., Jan 1 2018, Advances in Biochemical Engineering/Biotechnology. Springer Science and Business Media Deutschland GmbH, (Advances in Biochemical Engineering/Biotechnology; vol. 162).

Research output: Chapter in Book/Report/Conference proceedingChapter

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

Lian, J., HamediRad, M. & Zhao, H., Sep 2018, In : Biotechnology Journal. 13, 9, 1700601.

Research output: Contribution to journalReview article

2017

A Scalable Epitope Tagging Approach for High Throughput ChIP-Seq Analysis

Xiong, X., Zhang, Y., Yan, J., Jain, S., Chee, S., Ren, B. & Zhao, H., Jun 16 2017, In : ACS synthetic biology. 6, 6, p. 1034-1042 9 p.

Research output: Contribution to journalArticle

Orthogonal Genetic Regulation in Human Cells Using Chemically Induced CRISPR/Cas9 Activators

Bao, Z., Jain, S., Jaroenpuntaruk, V. & Zhao, H., Apr 21 2017, In : ACS synthetic biology. 6, 4, p. 686-693 8 p.

Research output: Contribution to journalArticle

2019

A pathway for isethionate dissimilation in Bacillus krulwichiae

Tong, Y., Wei, Y., Hu, Y., Ang, E. L., Zhao, H. & Zhang, Y., Jan 1 2019, In : Applied and environmental microbiology. 85, 15, e00793-19.

Research output: Contribution to journalArticle

2018

Applying advanced dna assembly methods to generate pathway libraries

Eriksen, D. T., Chao, R. & Zhao, H., Mar 15 2018, Synthetic Biology: Parts, Devices and Applications. Wiley-VCH Verlag, p. 331-347 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Standardization for natural product synthetic biology

Zhao, H. & Medema, M. H., Aug 2016, In : Natural Product Reports. 33, 8, p. 920-924 5 p.

Research output: Contribution to journalReview article

2018

Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR-Cas9 Activation

Lim, Y. H., Wong, F. T., Yeo, W. L., Ching, K. C., Lim, Y. W., Heng, E., Chen, S., Tsai, D. J., Lauderdale, T. L., Shia, K. S., Ho, Y. S., Hoon, S., Ang, E. L., Zhang, M. M. & Zhao, H., Aug 16 2018, In : ChemBioChem. 19, 16, p. 1716-1719 4 p.

Research output: Contribution to journalArticle

2019

Identification and characterization of a new sulfoacetaldehyde reductase from the human gut bacterium Bifidobacterium kashiwanohense

Zhou, Y., Wei, Y., Nanjaraj Urs, A. N., Lin, L., Xu, T., Hu, Y., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jan 1 2019, In : Bioscience Reports. 39, 6, Y.

Research output: Contribution to journalArticle

Open Access
2018

Quantifying the effects of pollen nutrition on honey bee queen egg laying with a new laboratory system

Fine, J. D., Shpigler, H. Y., Ray, A. M., Beach, N. J., Sankey, A. L., Cash-Ahmed, A., Huang, Z. Y., Astrauskaite, I., Chao, R., Zhao, H. & Robinson, G. E., Sep 2018, In : PloS one. 13, 9, e0203444.

Research output: Contribution to journalArticle

2019

Biochemical and structural investigation of taurine:2-oxoglutarate aminotransferase from Bifidobacterium kashiwanohense

Li, M., Wei, Y., Yin, J., Lin, L., Zhou, Y., Hua, G., Cao, P., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jan 1 2019, In : Biochemical Journal. 476, 11, p. 1605-1619 15 p.

Research output: Contribution to journalArticle

2016

Members of the rusc protein family interact with Sufu and inhibit vertebrate hedgehog signaling

Jin, Z., Schwend, T., Fu, J., Bao, Z., Liang, J., Zhao, H., Mei, W. & Yang, J., Nov 1 2016, In : Development (Cambridge). 143, 21, p. 3944-3955 12 p.

Research output: Contribution to journalArticle

2017

Automated multiplex genome-scale engineering in yeast

Si, T., Chao, R., Min, Y., Wu, Y., Ren, W. & Zhao, H., Jan 1 2017, In : Nature communications. 8, 15187.

Research output: Contribution to journalArticle

2016

Combined and iterative use of computational design and directed evolution for protein-ligand binding design

Wang, M. & Zhao, H., May 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 139-153 15 p. (Methods in Molecular Biology; vol. 1414).

Research output: Chapter in Book/Report/Conference proceedingChapter

A step through the looking glass

Liang, Y., Ang, E. L. & Zhao, H., Sep 1 2016, In : Science China Life Sciences. 59, 9, p. 979-980 2 p.

Research output: Contribution to journalArticle

2018

Metabolic Engineering of Saccharomyces cerevisiae Using a Trifunctional CRISPR/Cas System for Simultaneous Gene Activation, Interference, and Deletion

Schultz, C., Lian, J. & Zhao, H., Jan 1 2018, Methods in Enzymology. Scrutton, N. (ed.). Academic Press Inc., p. 265-276 12 p. (Methods in Enzymology; vol. 608).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Biochemical and structural investigation of sulfoacetaldehyde reductase from Klebsiella oxytoca

Zhou, Y., Wei, Y., Lin, L., Xu, T., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jan 1 2019, In : Biochemical Journal. 476, 4, p. 733-746 14 p.

Research output: Contribution to journalArticle

2016

Metabolic engineering of a synergistic pathway for n-butanol production in Saccharomyces cerevisiae

Shi, S., Si, T., Liu, Z., Zhang, H., Ang, E. L. & Zhao, H., May 10 2016, In : Scientific reports. 6, 25675.

Research output: Contribution to journalArticle

High-Efficiency Genome Editing of Streptomyces Species by an Engineered CRISPR/Cas System

Wang, Y., Cobb, R. E. & Zhao, H., 2016, Methods in Enzymology. O'Connor, S. E. (ed.). Academic Press Inc., p. 271-284 14 p. (Methods in Enzymology; vol. 575).

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes

Tapsin, S., Sun, M., Shen, Y., Zhang, H., Lim, X. N., Susanto, T. T., Yang, S. L., Zeng, G. S., Lee, J., Lezhava, A., Ang, E. L., Zhang, L. H., Wang, Y., Zhao, H., Nagarajan, N. & Wan, Y., Dec 1 2018, In : Nature communications. 9, 1, 1289.

Research output: Contribution to journalArticle