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2017

The omics side of fatty liver: A holistic approach for a commonly occurring peripartal disease

Vailati-Riboni, M., Palombo, V. & Loor, J. J., Jan 1 2017, Periparturient Diseases of Dairy Cows: A Systems Biology Approach. Springer International Publishing, p. 223-246 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

fatty liver
metabolic diseases
Fatty Liver
Liver
Dairies
2019

L-Arginine protects ovine intestinal epithelial cells from lipopolysaccharide-induced intestinal barrier injury

Zhang, H., Jin, Y., Peng, A., Guo, S., Loor, J. J. & Wang, H., Jan 1 2019, In : Food and Agricultural Immunology. 30, 1, p. 1067-1084 18 p.

Research output: Contribution to journalArticle

Open Access
lipopolysaccharides
arginine
Lipopolysaccharides
Arginine
Sheep
2016

Maternal Plane of Nutrition during Late-Gestation and Weaning Age Alter Steer Calf Longissimus Muscle Adipogenic MicroRNA and Target Gene Expression

Moisá, S. J., Shike, D. W., Shoup, L. & Loor, J. J., Jan 1 2016, In : Lipids. 51, 1, p. 123-138 16 p.

Research output: Contribution to journalArticle

Nutrition
Weaning
MicroRNAs
Gene expression
Muscle
2017

Rapid communication: Period2 gene silencing increases the synthesis of αs–casein protein in bovine mammary epithelial cells

Hu, L. Y., Wang, M. Z., Ouyang, J. L., Li, P. F. & Loor, J. J., Oct 2017, In : Journal of animal science. 95, 10, p. 4510-4513 4 p.

Research output: Contribution to journalArticle

Gene Silencing
gene silencing
animal communication
breasts
Breast
2015

Short communication: Effect of inhibition of fatty acid synthase on triglyceride accumulation and effect on lipid metabolism genes in goat mammary epithelial cells

Zhu, J. J., Luo, J., Sun, Y. T., Shi, H. B., Li, J., Wu, M., Yu, K., Haile, A. B. & Loor, J. J., May 1 2015, In : Journal of Dairy Science. 98, 5, p. 3485-3491 7 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
fatty-acid synthase
Lipid Metabolism
Goats
lipid metabolism
2017

miR-148a and miR-17–5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells

Chen, Z., Luo, J., Sun, S., Cao, D., Shi, H. & Loor, J. J., Mar 4 2017, In : RNA Biology. 14, 3, p. 326-338 13 p.

Research output: Contribution to journalArticle

Goats
Milk
Triglycerides
Breast
Epithelial Cells
2019

Transcriptome analysis of the effects of fasting caecotrophy on hepatic lipid metabolism in New Zealand rabbits

Wang, Y., Xu, H., Sun, G., Xue, M., Sun, S., Huang, T., Zhou, J., Loor, J. J. & Li, M., Sep 2019, In : Animals. 9, 9, 648.

Research output: Contribution to journalArticle

Open Access
Gene Expression Profiling
transcriptomics
Lipid Metabolism
lipid metabolism
fasting
2016

Effect of dietary vegetable oils on the fatty acid profile of plasma lipoproteins in dairy cows

Vargas-Bello-Pérez, E., Íñiguez-González, G., Cancino-Padilla, N., Loor, J. J. & Garnsworthy, P. C., Jul 3 2016, In : Archives of Animal Nutrition. 70, 4, p. 322-332 11 p.

Research output: Contribution to journalArticle

Unsaturated Dietary Fats
Soybean Oil
Plant Oils
vegetable oil
lipoproteins
2017

Grain challenge affects systemic and hepatic molecular biomarkers of inflammation, stress, and metabolic responses to a greater extent in Holstein than Jersey cows

Xu, T., Cardoso, F. C., Pineda, A., Trevisi, E., Shen, X., Rosa, F., Osorio, J. S. & Loor, J. J., Nov 2017, In : Journal of Dairy Science. 100, 11, p. 9153-9162 10 p.

Research output: Contribution to journalArticle

TOR Serine-Threonine Kinases
Physiological Stress
Jersey
biomarkers
Holstein
2019

Regulation of Stearoyl-Coenzyme A Desaturase 1 by trans-10, cis-12 Conjugated Linoleic Acid via SREBP1 in Primary Goat Mammary Epithelial Cells

Zhang, T., Li, C., Huang, L., Song, N., Cao, Y., Loor, J. J., Luo, J. & Shi, H., Feb 6 2019, In : Journal of Agricultural and Food Chemistry. 67, 5, p. 1463-1469 7 p.

Research output: Contribution to journalArticle

stearoyl-CoA desaturase
conjugated linoleic acid
Goats
breasts
Breast
2016

Nutritional systems biology to elucidate adaptations in lactation physiology of dairy cows

Vailati-Riboni, M., Elolimy, A. & Loor, J. J., Jan 1 2016, Systems Biology in Animal Production and Health, Vol. 2. Springer International Publishing, p. 97-125 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Systems Biology
Dairies
Rumen
Physiology
Nutrition
2019

High expression of cell death-inducing DFFA-like effector a (CIDEA) promotes milk fat content in dairy cows with clinical ketosis

Sun, X., Wang, Y., Loor, J. J., Bucktrout, R., Shu, X., Jia, H., Dong, J., Zuo, R., Liu, G., Li, X. & Li, X., Feb 2019, In : Journal of Dairy Science. 102, 2, p. 1682-1692 11 p.

Research output: Contribution to journalArticle

Ketosis
ketosis
milk fat
cell death
Milk
2016

Short communication: Altered expression of specificity protein 1 impairs milk fat synthesis in goat mammary epithelial cells

Zhu, J. J., Luo, J., Xu, H. F., Wang, H. & Loor, J. J., Jun 1 2016, In : Journal of Dairy Science. 99, 6, p. 4893-4898 6 p., 74515.

Research output: Contribution to journalArticle

Goats
animal communication
milk fat
Small Interfering RNA
droplets
2017

miR-26b promoter analysis reveals regulatory mechanisms by lipid-related transcription factors in goat mammary epithelial cells

Wang, H., Luo, J., He, Q., Yao, D., Wu, J. & Loor, J. J., Jul 2017, In : Journal of Dairy Science. 100, 7, p. 5837-5849 13 p.

Research output: Contribution to journalArticle

Goats
breasts
Breast
epithelial cells
Transcription Factors
2019

Inflammation and oxidative stress transcription profiles due to in vitro supply of methionine with or without choline in unstimulated blood polymorphonuclear leukocytes from lactating Holstein cows

Lopreiato, V., Vailati-Riboni, M., Bellingeri, A., Khan, I., Farina, G., Parys, C. & Loor, J. J., Nov 2019, In : Journal of Dairy Science. 102, 11, p. 10395-10410 16 p.

Research output: Contribution to journalArticle

Open Access
choline
Choline
Methionine
methionine
neutrophils
2016

Effect of short-chain fatty acids on triacylglycerol accumulation, lipid droplet formation and lipogenic gene expression in goat mammary epithelial cells

Sun, Y., Luo, J., Zhu, J., Shi, H., Li, J., Qiu, S., Wang, P. & Loor, J. J., Feb 1 2016, In : Animal Science Journal. 87, 2, p. 242-249 8 p.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Butyrates
Propionates
short chain fatty acids
butyrates
2015

Identification and characterization of microRNA sequences from bovine mammary epithelial cells

Bu, D. P., Nan, X. M., Wang, F., Loor, J. J. & Wang, J. Q., Mar 1 2015, In : Journal of Dairy Science. 98, 3, p. 1696-1705 10 p.

Research output: Contribution to journalArticle

MicroRNAs
microRNA
breasts
Breast
epithelial cells
2019

Hepatic 1-carbon metabolism enzyme activity, intermediate metabolites, and growth in neonatal Holstein dairy calves are altered by maternal supply of methionine during late pregnancy

Alharthi, A. S., Coleman, D. N., Liang, Y., Batistel, F., Elolimy, A. A., Yambao, R. C., Abdel-Hamied, E., Pan, Y. X., Parys, C., Alhidary, I. A., Abdelrahman, M. M. & Loor, J. J., Nov 2019, In : Journal of Dairy Science. 102, 11, p. 10291-10303 13 p.

Research output: Contribution to journalArticle

dairy calves
Methionine
methionine
Holstein
Carbon
2017

Effects of precalving body condition and prepartum feeding level on gene expression in circulating neutrophils

Crookenden, M. A., Walker, C. G., Heiser, A., Murray, A., Dukkipati, V. S. R., Kay, J. K., Meier, S., Moyes, K. M., Mitchell, M. D., Loor, J. J. & Roche, J. R., Mar 1 2017, In : Journal of Dairy Science. 100, 3, p. 2310-2322 13 p.

Research output: Contribution to journalArticle

feeding level
body condition
neutrophils
Neutrophils
Gene Expression
2015
fibroblast growth factors
Ketosis
ketosis
Nutrition
Holstein
2019

Effect of different exogenous fatty acids on the cytosolic triacylglycerol content in bovine mammary cells

Vargas-Bello-Pérez, E., Loor, J. J. & Garnsworthy, P. C., Jun 2019, In : Animal Nutrition. 5, 2, p. 202-208 7 p.

Research output: Contribution to journalArticle

breasts
Triglycerides
Breast
Fatty Acids
triacylglycerols
2017

Reticulo-rumen mass, epithelium gene expression, and systemic biomarkers of metabolism and inflammation in Holstein dairy cows fed a high-energy diet

Arroyo, J. M., Hosseini, A., Zhou, Z., Alharthi, A., Trevisi, E., Osorio, J. S. & Loor, J. J., Nov 2017, In : Journal of Dairy Science. 100, 11, p. 9352-9360 9 p.

Research output: Contribution to journalArticle

high energy diet
Rumen
rumen
biomarkers
Holstein
2019

Monensin controlled-release capsule administered in late-pregnancy differentially affects rumination patterns, metabolic status, and cheese-making properties of the milk in primiparous and multiparous cows

Mezzetti, M., Piccioli-Cappelli, F., Bani, P., Amadori, M., Calamari, L., Minuti, A., Loor, J. J., Bionaz, M. & Trevisi, E., Jan 1 2019, In : Italian Journal of Animal Science. 18, 1, p. 1271-1283 13 p.

Research output: Contribution to journalArticle

Open Access
rumination
monensin
cheesemaking
pregnancy
cows
2015

Transcriptome profiles of whole blood in Italian Holstein and Italian Simmental lactating cows diverging for genetic merit for milk protein

Sandri, M., Stefanon, B. & Loor, J. J., Sep 1 2015, In : Journal of Dairy Science. 98, 9, p. 6119-6127 9 p.

Research output: Contribution to journalArticle

genetic merit
Milk Proteins
Simmental
dairy protein
Transcriptome
2017

What are omics sciences?

Vailati-Riboni, M., Palombo, V. & Loor, J. J., Jan 1 2017, Periparturient Diseases of Dairy Cows: A Systems Biology Approach. Springer International Publishing, p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolomics
metabolomics
metabolome
Metabolites
Molecules
choline
Choline
Methionine
methionine
Carbon
2019
Open Access
Rumen
Methionine
adipose tissue
Glutathione
Adipose Tissue
2016

Short communication: Proteins from circulating exosomes represent metabolic state in transition dairy cows

Crookenden, M. A., Walker, C. G., Peiris, H., Koh, Y., Heiser, A., Loor, J. J., Moyes, K. M., Murray, A., Dukkipati, V. S. R., Kay, J. K., Meier, S., Roche, J. R. & Mitchell, M. D., Sep 1 2016, In : Journal of Dairy Science. 99, 9, p. 7661-7668 8 p.

Research output: Contribution to journalArticle

exosomes
Exosomes
animal communication
dairy cows
Communication
2015

Triennial lactation symposium: Nutrigenomics in dairy cows: Nutrients, transcription factors, and techniques

Bionaz, M., Osorio, J. & Loor, J. J., Dec 18 2015, In : Journal of animal science. 93, 12, p. 5531-5553 23 p.

Research output: Contribution to journalArticle

Nutrigenomics
nutrigenomics
Lactation
Transcription Factors
dairy cows
2016

Immunometabolic status during the peripartum period is enhanced with supplemental Zn, Mn, and Cu from amino acid complexes and Co from Co glucoheptonate

Batistel, F., Osorio, J. S., Ferrari, A., Trevisi, E., Socha, M. T. & Loor, J. J., May 2016, In : PloS one. 11, 5, e0155804.

Research output: Contribution to journalArticle

Peripartum Period
Nutrition
Liver
Diet
Trace Elements

Rumen-protected methionine compared with rumen-protected choline improves immunometabolic status in dairy cows during the peripartal period

Zhou, Z., Bulgari, O., Vailati-Riboni, M., Trevisi, E., Ballou, M. A., Cardoso, F., Luchini, D. N. & Loor, J. J., Nov 1 2016, In : Journal of Dairy Science. 99, 11, p. 8956-8969 14 p.

Research output: Contribution to journalArticle

Rumen
choline
Choline
Methionine
methionine
2017

Application of nutrigenomics in small ruminants: Lactation, growth, and beyond

Osorio, J. S., Vailati-Riboni, M., Palladino, A., Luo, J. & Loor, J. J., Sep 2017, In : Small Ruminant Research. 154, p. 29-44 16 p.

Research output: Contribution to journalReview article

Nutrigenomics
nutrigenomics
Ruminants
small ruminants
Lactation

Supplementation with rumen-protected methionine or choline during the transition period influences whole-blood immune response in periparturient dairy cows

Vailati-Riboni, M., Zhou, Z., Jacometo, C. B., Minuti, A., Trevisi, E., Luchini, D. N. & Loor, J. J., May 2017, In : Journal of Dairy Science. 100, 5, p. 3958-3968 11 p.

Research output: Contribution to journalArticle

Rumen
choline
Choline
Methionine
methionine
2015

Expression of NGF, BDNF and their receptors in subcutaneous adipose tissue of lactating cows

Colitti, M., Loor, J. J. & Stefanon, B., Oct 1 2015, In : Research in Veterinary Science. 102, p. 196-199 4 p.

Research output: Contribution to journalArticle

trkB Receptor
nerve growth factor
neurotrophins
Subcutaneous Fat
Brain-Derived Neurotrophic Factor
2016

Maternal rumen-protected methionine supplementation and its effect on blood and liver biomarkers of energy metabolism, inflammation, and oxidative stress in neonatal Holstein calves

Jacometo, C. B., Zhou, Z., Luchini, D., Trevisi, E., Corrêa, M. N. & Loor, J. J., Aug 1 2016, In : Journal of Dairy Science. 99, 8, p. 6753-6763 11 p.

Research output: Contribution to journalArticle

Rumen
Methionine
energy metabolism
Energy Metabolism
methionine
cobalt
Cobalt
neutrophils
Neutrophils
Diet
2017
Betaine-Homocysteine S-Methyltransferase
Rumen
Methionine
methionine
rumen
2016

Prepartum body condition score and plane of nutrition affect the hepatic transcriptome during the transition period in grazing dairy cows

Vailati-Riboni, M., Meier, S., Burke, C. R., Kay, J. K., Mitchell, M. D., Walker, C. G., Crookenden, M. A., Heiser, A., Rodriguez-Zas, S. L., Roche, J. R. & Loor, J. J., Nov 2 2016, In : BMC genomics. 17, 1, 854.

Research output: Contribution to journalArticle

Transcriptome
Liver
Lactation
Amino Acids
Carbohydrates
2017

Ethyl-cellulose rumen-protected methionine enhances performance during the periparturient period and early lactation in Holstein dairy cows

Batistel, F., Arroyo, J. M., Bellingeri, A., Wang, L., Saremi, B., Parys, C., Trevisi, E., Cardoso, F. C. & Loor, J. J., Sep 2017, In : Journal of Dairy Science. 100, 9, p. 7455-7467 13 p.

Research output: Contribution to journalArticle

Rumen
early lactation
Lactation
Methionine
methionine
TOR Serine-Threonine Kinases
Birth Weight
Methionine
Placenta
Sirolimus
2019

Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows

Shen, T., Li, X., Loor, J. J., Zhu, Y., Du, X., Wang, X., Xing, D., Shi, Z., Fang, Z., Li, X. & Liu, G., Nov 2019, In : Journal of Dairy Science. 102, 11, p. 10554-10563 10 p.

Research output: Contribution to journalArticle

Inflammasomes
Ketosis
ketosis
NF-kappa B
dairy cows
2015

Triennial Lactation symposium: Nutrigenomics in livestock: Systems biology meets nutrition

Loor, J. J., Vailati-Riboni, M., McCann, J. C., Zhou, Z. & Bionaz, M., Dec 18 2015, In : Journal of animal science. 93, 12, p. 5554-5574 21 p.

Research output: Contribution to journalArticle

Nutrigenomics
nutrigenomics
Systems Biology
Livestock
Lactation

Stress and inflammatory gene networks in bovine liver are altered by plane of dietary energy during late pregnancy

Khan, M. J., Jacometo, C. B., Vailati Riboni, M., Trevisi, E., Graugnard, D. E., Corrêa, M. N. & Loor, J. J., Sep 10 2015, In : Functional and Integrative Genomics. 15, 5, p. 563-576 14 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Endoplasmic Reticulum Stress
Parturition
Pregnancy
Liver
2016

Corium molecular biomarkers reveal a beneficial effect on hoof transcriptomics in peripartal dairy cows supplemented with zinc, manganese, and copper from amino acid complexes and cobalt from cobalt glucoheptonate

Osorio, J. S., Batistel, F., Garrett, E. F., Elhanafy, M. M., Tariq, M. R., Socha, M. T. & Loor, J. J., Dec 1 2016, In : Journal of Dairy Science. 99, 12, p. 9974-9982 9 p.

Research output: Contribution to journalArticle

Hoof and Claw
hooves
Dermis
cobalt
Manganese
2019

N-Carbamylglutamate and l-Arginine Promote Intestinal Absorption of Amino Acids by Regulating the mTOR Signaling Pathway and Amino Acid and Peptide Transporters in Suckling Lambs with Intrauterine Growth Restriction

Zhang, H., Peng, A., Yu, Y., Guo, S., Wang, M., Coleman, D. N., Loor, J. J. & Wang, H., Jan 1 2019, In : Journal of Nutrition. 149, 6, p. 923-932 10 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Intestinal Absorption
Sirolimus
Arginine
Amino Acids
2016

Induction of subacute ruminal acidosis affects the ruminal microbiome and epithelium

McCann, J. C., Luan, S., Cardoso, F. C., Derakhshani, H., Khafipour, E. & Loor, J. J., Jan 1 2016, In : Frontiers in Microbiology. 7, MAY, 701.

Research output: Contribution to journalArticle

Microbiota
Acidosis
Epithelium
Prevotella
Diet
2017

Nuclear receptor subfamily 1 group H member 2 (LXRB) is the predominant liver X receptor subtype regulating transcription of 2 major lipogenic genes in goat primary mammary epithelial cells

Shi, H. B., Zhang, C. H., Xu, Z. A., Xu, X. F., Lv, Z. B., Luo, J. & Loor, J. J., Aug 2017, In : Journal of Dairy Science. 100, 8, p. 6743-6752 10 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Fatty Acid Synthases
major genes
fatty-acid synthase
Goats
Betaine-Homocysteine S-Methyltransferase
Cystathionine
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Choline
Methionine
2015

Acute mammary and liver transcriptome responses after an intramammary escherichia coli lipopolysaccharide challenge in postpartal dairy cows

Minuti, A., Zhou, Z., Graugnard, D. E., Rodriguezzas, S. L., Palladino, A. R., Cardoso, F. C., Trevisi, E. & Loor, J. J., Jan 1 2015, In : Physiological Reports. 3, 4, e12388.

Research output: Contribution to journalArticle

Transcriptome
Lipopolysaccharides
Breast
Escherichia coli
Liver
2017

Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells

Bulgari, O., Dong, X., Roca, A. L., Caroli, A. M. & Loor, J. J., Apr 1 2017, In : Journal of Animal Science and Biotechnology. 8, 1, 29.

Research output: Contribution to journalArticle

Chemokine CXCL6
C Chemokines
prostaglandin synthase
Prostaglandin-Endoperoxide Synthases
Toll-Like Receptor 4