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2019

Enhanced supply of methionine or arginine alters mechanistic target of rapamycin signaling proteins, messenger RNA, and microRNA abundance in heat-stressed bovine mammary epithelial cells in vitro

Salama, A. A. K., Duque, M., Wang, L., Shahzad, K., Olivera, M. & Loor, J. J., Mar 2019, In : Journal of Dairy Science. 102, 3, p. 2469-2480 12 p.

Research output: Contribution to journalArticle

Open Access
TOR Serine-Threonine Kinases
messenger RNA
MicroRNAs
microRNA
Methionine
2018

Skeletal muscle and liver gene expression profiles in finishing steers supplemented with Amaize

Elolimy, A. A., Moisá, S. J., Brennan, K. M., Smith, A. C., Graugnard, D., Shike, D. W. & Loor, J. J., Aug 2018, In : Animal Science Journal. 89, 8, p. 1107-1119 13 p.

Research output: Contribution to journalArticle

Transcriptome
skeletal muscle
finishing
Skeletal Muscle
gene expression
2016

MicroRNA-26a/b and their host genes synergistically regulate triacylglycerol synthesis by targeting the INSIG1 gene

Wang, H., Luo, J., Zhang, T., Tian, H., Ma, Y., Xu, H., Yao, D. & Loor, J. J., Apr 13 2016, In : RNA Biology. 13, 5, p. 500-510 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Triglycerides
Insulin
Genes
Goats
2019

Hepatic 1-carbon metabolism enzyme activity, intermediate metabolites, and growth in neonatal Holstein dairy calves are altered by maternal supply of methionine during late pregnancy

Alharthi, A. S., Coleman, D. N., Liang, Y., Batistel, F., Elolimy, A. A., Yambao, R. C., Abdel-Hamied, E., Pan, Y. X., Parys, C., Alhidary, I. A., Abdelrahman, M. M. & Loor, J. J., Nov 2019, In : Journal of Dairy Science. 102, 11, p. 10291-10303 13 p.

Research output: Contribution to journalArticle

dairy calves
Methionine
methionine
Holstein
Carbon
Betaine-Homocysteine S-Methyltransferase
betaine-homocysteine S-methyltransferase
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
methionine synthase
choline
2015

Transcriptome profiles of whole blood in Italian Holstein and Italian Simmental lactating cows diverging for genetic merit for milk protein

Sandri, M., Stefanon, B. & Loor, J. J., Sep 1 2015, In : Journal of Dairy Science. 98, 9, p. 6119-6127 9 p.

Research output: Contribution to journalArticle

genetic merit
Milk Proteins
Simmental
dairy protein
Transcriptome

Triennial lactation symposium: Nutrigenomics in dairy cows: Nutrients, transcription factors, and techniques

Bionaz, M., Osorio, J. & Loor, J. J., Dec 18 2015, In : Journal of animal science. 93, 12, p. 5531-5553 23 p.

Research output: Contribution to journalArticle

Nutrigenomics
nutrigenomics
Lactation
Transcription Factors
dairy cows

Maternal consumption of organic trace minerals alters calf systemic and neutrophil mRNA and microRNA indicators of inflammation and oxidative stress

Jacometo, C. B., Osorio, J. S., Socha, M., Corrêa, M. N., Piccioli-Cappelli, F., Trevisi, E. & Loor, J. J., Nov 2015, In : Journal of Dairy Science. 98, 11, p. 7717-7729 13 p., 73889.

Research output: Contribution to journalArticle

Trace Elements
MicroRNAs
microRNA
trace elements
neutrophils
2017

Effect of circulating exosomes from transition cows on Madin-Darby bovine kidney cell function

Crookenden, M. A., Walker, C. G., Peiris, H., Koh, Y., Almughlliq, F., Vaswani, K., Reed, S., Heiser, A., Loor, J. J., Kay, J. K., Meier, S., Donkin, S. S., Murray, A., Dukkipati, V. S. R., Roche, J. R. & Mitchell, M. D., Jul 2017, In : Journal of Dairy Science. 100, 7, p. 5687-5700 14 p.

Research output: Contribution to journalArticle

exosomes
Exosomes
kidney cells
Kidney
cows
2016

Dietary impacts on rumen microbiota in beef and dairy production

Loor, J. J., Elolimy, A. A. & McCann, J. C., Jul 1 2016, In : Animal Frontiers. 6, 3, p. 22-29 8 p.

Research output: Contribution to journalArticle

Microbiota
Rumen
milk production
rumen
beef
2015

Short communication: Effect of inhibition of fatty acid synthase on triglyceride accumulation and effect on lipid metabolism genes in goat mammary epithelial cells

Zhu, J. J., Luo, J., Sun, Y. T., Shi, H. B., Li, J., Wu, M., Yu, K., Haile, A. B. & Loor, J. J., May 1 2015, In : Journal of Dairy Science. 98, 5, p. 3485-3491 7 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
fatty-acid synthase
Lipid Metabolism
Goats
lipid metabolism
2017

Strategies to gain body condition score in pasture-based dairy cows during late lactation and the far-off nonlactating period and their interaction with close-up dry matter intake

Roche, J. R., Heiser, A., Mitchell, M. D., Crookenden, M. A., Walker, C. G., Kay, J. K., Riboni, M. V., Loor, J. J. & Meier, S., Mar 1 2017, In : Journal of Dairy Science. 100, 3, p. 1720-1738 19 p.

Research output: Contribution to journalArticle

late lactation
Lactation
dry matter intake
body condition
dairy cows
2018

Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells

Xu, H., Luo, J., Ma, G., Zhang, X., Yao, D., Li, M. & Loor, J. J., Feb 1 2018, In : Journal of Cellular Physiology. 233, 2, p. 1005-1016 12 p.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Sterol Regulatory Element Binding Protein 1
Breast
Fatty Acids
Epithelial Cells
2019

Phosphorylation of AKT serine/threonine kinase and abundance of milk protein synthesis gene networks in mammary tissue in response to supply of methionine in periparturient Holstein cows

Ma, Y. F., Batistel, F., Xu, T. L., Han, L. Q., Bucktrout, R., Liang, Y., Coleman, D. N., Parys, C. & Loor, J. J., May 2019, In : Journal of Dairy Science. 102, 5, p. 4264-4274 11 p.

Research output: Contribution to journalArticle

Open Access
Ribosomal Protein S6
Gene Regulatory Networks
Milk Proteins
Protein-Serine-Threonine Kinases
dairy protein
2016

Rumen-protected methionine compared with rumen-protected choline improves immunometabolic status in dairy cows during the peripartal period

Zhou, Z., Bulgari, O., Vailati-Riboni, M., Trevisi, E., Ballou, M. A., Cardoso, F., Luchini, D. N. & Loor, J. J., Nov 1 2016, In : Journal of Dairy Science. 99, 11, p. 8956-8969 14 p.

Research output: Contribution to journalArticle

Rumen
choline
Choline
Methionine
methionine
2018

Serotonin induces parathyroid hormone-related protein in goat mammary gland

Zang, W. J., Li, H., Zhang, Z. F., QuZhen, R., CuoMu, Y. Z., Zhang, D. K., Luo, J., Loor, J. J. & Zheng, H. L., Apr 3 2018, In : Journal of animal science. 96, 3, p. 1010-1016 7 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
parathyroid hormone
Human Mammary Glands
serotonin
Goats
2017

miR-26b promoter analysis reveals regulatory mechanisms by lipid-related transcription factors in goat mammary epithelial cells

Wang, H., Luo, J., He, Q., Yao, D., Wu, J. & Loor, J. J., Jul 2017, In : Journal of Dairy Science. 100, 7, p. 5837-5849 13 p.

Research output: Contribution to journalArticle

Goats
breasts
Breast
epithelial cells
Transcription Factors
2019

Perilipin 5 promotes hepatic steatosis in dairy cows through increasing lipid synthesis and decreasing very low density lipoprotein assembly

Jia, H., Li, X., Liu, G., Loor, J. J., Bucktrout, R., Sun, X., Li, G., Shu, X., Dong, J., Wang, Y., Zuo, R., Wang, Z. & Li, X., Jan 2019, In : Journal of Dairy Science. 102, 1, p. 833-845 13 p.

Research output: Contribution to journalArticle

VLDL Lipoproteins
very low density lipoprotein
fatty liver
Fatty Liver
dairy cows
2016

Short communication: Altered expression of specificity protein 1 impairs milk fat synthesis in goat mammary epithelial cells

Zhu, J. J., Luo, J., Xu, H. F., Wang, H. & Loor, J. J., Jun 1 2016, In : Journal of Dairy Science. 99, 6, p. 4893-4898 6 p., 74515.

Research output: Contribution to journalArticle

Goats
animal communication
milk fat
Small Interfering RNA
droplets
2015

Prepartal dietary energy level affects peripartal bovine blood neutrophil metabolic, antioxidant, and inflammatory gene expression

Zhou, Z., Bu, D. P., Vailati Riboni, M., Khan, M. J., Graugnard, D. E., Luo, J., Cardoso, F. & Loor, J. J., Aug 1 2015, In : Journal of Dairy Science. 98, 8, p. 5492-5505 14 p.

Research output: Contribution to journalArticle

neutrophils
Neutrophils
Antioxidants
Gene Expression
antioxidants
2016

Parturition in dairy cows temporarily alters the expression of genes in circulating neutrophils

Crookenden, M. A., Heiser, A., Murray, A., Dukkipati, V. S. R., Kay, J. K., Loor, J. J., Meier, S., Mitchell, M. D., Moyes, K. M., Walker, C. G. & Roche, J. R., Aug 1 2016, In : Journal of Dairy Science. 99, 8, p. 6470-6483 14 p.

Research output: Contribution to journalArticle

neutrophils
Neutrophils
dairy cows
Parturition
parturition
2018

Maternal supply of methionine during late-pregnancy enhances rate of Holstein calf development in utero and postnatal growth to a greater extent than colostrum source

Alharthi, A. S., Batistel, F., Abdelmegeid, M. K., Lascano, G., Parys, C., Helmbrecht, A., Trevisi, E. & Loor, J. J., Jan 1 2018, In : Journal of Animal Science and Biotechnology. 9, 1, 83.

Research output: Contribution to journalArticle

Open Access
Colostrum
Pregnancy Rate
colostrum
pregnancy rate
Methionine

Rumen-protected methionine during the peripartal period in dairy cows and its effects on abundance of major species of ruminal bacteria

Abdelmegeid, M. K., Elolimy, A. A., Zhou, Z., Lopreiato, V., McCann, J. C. & Loor, J. J., Feb 7 2018, In : Journal of Animal Science and Biotechnology. 9, 1, 17.

Research output: Contribution to journalArticle

rumen bacteria
Dairies
Rumen
Methionine
methionine
2015

Triennial Lactation symposium: Nutrigenomics in livestock: Systems biology meets nutrition

Loor, J. J., Vailati-Riboni, M., McCann, J. C., Zhou, Z. & Bionaz, M., Dec 18 2015, In : Journal of animal science. 93, 12, p. 5554-5574 21 p.

Research output: Contribution to journalArticle

Nutrigenomics
nutrigenomics
Systems Biology
Livestock
Lactation
2017

Effects of dietary neutral detergent fiber and starch ratio on rumen epithelial cell morphological structure and gene expression in dairy cows

Ma, L., Zhao, M., Zhao, L. S., Xu, J. C., Loor, J. J. & Bu, D. P., May 2017, In : Journal of Dairy Science. 100, 5, p. 3705-3712 8 p.

Research output: Contribution to journalArticle

Rumen
Starch
Detergents
neutral detergent fiber
rumen
2016

Secretion of glucagon-like peptide-2 responds to nutrient intake but not glucose provision in milk-fed calves

Castro, J. J., Morrison, S. Y., Hosseinni, A., Loor, J. J., Drackley, J. K. & Ipharraguerre, I. R., Jul 1 2016, In : Journal of Dairy Science. 99, 7, p. 5793-5807 15 p., 74601.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 2
nutrient intake
Milk
secretion
calves
2017
choline
Choline
Methionine
methionine
Carbon
2016

Circulating amino acids in blood plasma during the peripartal period in dairy cows with different liver functionality index

Zhou, Z., Loor, J. J., Piccioli-Cappelli, F., Librandi, F., Lobley, G. E. & Trevisi, E., Mar 1 2016, In : Journal of Dairy Science. 99, 3, p. 2257-2267 11 p.

Research output: Contribution to journalArticle

blood plasma
dairy cows
Amino Acids
liver
amino acids
2019

Tilmicosin modulates the innate immune response and preserves casein production in bovine mammary alveolar cells during Staphylococcus aureus infection

Martínez-Corts, I., Acevedo-Domínguez, N. A., Olguin-Alor, R., Corts-Hernández, A., Álvarez-Jiḿnez, V., Campillo-Navarro, M., Sumano-López, H. S., Gutírrez-Olvera, L., Martínez-Gómez, D., Maravillas-Montero, J. L., Loor, J. J., García-Zepeda, E. A. & Soldevila, G., Feb 1 2019, In : Journal of animal science. 97, 2, p. 644-656 13 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Caseins
Innate Immunity
breasts
preserves
2017

Linking peripartal dynamics of ruminal microbiota to dietary changes and production parameters

Derakhshani, H., Tun, H. M., Cardoso, F. C., Plaizier, J. C., Khafipour, E. & Loor, J. J., Jan 12 2017, In : Frontiers in Microbiology. 7, JAN, 2143.

Research output: Contribution to journalArticle

Microbiota
Rumen
Acclimatization
Lactation
Milk

What are omics sciences?

Vailati-Riboni, M., Palombo, V. & Loor, J. J., Jan 1 2017, Periparturient Diseases of Dairy Cows: A Systems Biology Approach. Springer International Publishing, p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolomics
metabolomics
metabolome
Metabolites
Molecules
2019

Effects of arginase inhibition via jugular infusion of N ω -hydroxy-nor-L-arginine on metabolic and immune indices in lactating dairy cows

Ding, L. Y., Wang, Y. F., Shen, Y. Z., Zhou, G., Zhang, X., Wang, M. Z., Loor, J. J. & Zhang, J., Apr 2019, In : Journal of Dairy Science. 102, 4, p. 3310-3320 11 p.

Research output: Contribution to journalArticle

Arginase
arginase
dairy protein
neck
arginine

Cellular Mechanisms and Epigenetic Changes: Role of Nutrition in Livestock

Elolimy, A., Vailati-Riboni, M., Liang, Y. & Loor, J. J., Jul 2019, In : Veterinary Clinics of North America - Food Animal Practice. 35, 2, p. 249-263 15 p.

Research output: Contribution to journalReview article

Livestock
Epigenomics
epigenetics
livestock
nutrition

Effect of heat-shock protein B7 on oxidative stress in adipocytes from preruminant calves

Sun, X., Li, X., Jia, H., Loor, J. J., Bucktrout, R., Xu, Q., Wang, Y., Shu, X., Dong, J., Zuo, R., Yang, L., Liu, G. & Li, X., Jun 2019, In : Journal of Dairy Science. 102, 6, p. 5673-5685 13 p.

Research output: Contribution to journalArticle

Heat-Shock Proteins
adipocytes
heat shock proteins
Adipocytes
Oxidative Stress
2015

Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows

Akbar, H., Grala, T. M., Vailati Riboni, M., Cardoso, F. C., Verkerk, G., McGowan, J., Macdonald, K., Webster, J., Schutz, K., Meier, S., Matthews, L., Roche, J. R. & Loor, J. J., Feb 1 2015, In : Journal of Dairy Science. 98, 2, p. 1019-1032 14 p.

Research output: Contribution to journalArticle

Transcriptome
transcriptome
body condition
calving
Milk
2017
Betaine-Homocysteine S-Methyltransferase
Rumen
Methionine
methionine
rumen
2018
Antioxidant Response Elements
heme oxygenase (biliverdin-producing)
response elements
breasts
Heme Oxygenase-1
2015

Identification and characterization of microRNA sequences from bovine mammary epithelial cells

Bu, D. P., Nan, X. M., Wang, F., Loor, J. J. & Wang, J. Q., Mar 1 2015, In : Journal of Dairy Science. 98, 3, p. 1696-1705 10 p.

Research output: Contribution to journalArticle

MicroRNAs
microRNA
breasts
Breast
epithelial cells
2019

Effects of rumen-protected betaine supplementation on meat quality and the composition of fatty and amino acids in growing lambs

Dong, L., Zhong, Z. X., Cui, H. H., Wang, S. N., Luo, Y., Yu, L. H., Loor, J. J. & Wang, H. R., Jan 1 2019, (Accepted/In press) In : Animal.

Research output: Contribution to journalArticle

betaine
amino acid composition
meat quality
rumen
lambs

N -carbamylglutamate and l-arginine promote intestinal function in suckling lambs with intrauterine growth restriction by regulating antioxidant capacity via a nitric oxide-dependent pathway

Zhang, H., Sun, H., Peng, A., Guo, S., Wang, M., Loor, J. J. & Wang, H., Oct 2019, In : Food and Function. 10, 10, p. 6374-6384 11 p.

Research output: Contribution to journalArticle

suckling
nitric oxide
arginine
Arginine
Nitric Oxide
2016

Prepartum feeding level and body condition score affect immunological performance in grazing dairy cows during the transition period

Lange, J., McCarthy, A., Kay, J., Meier, S., Walker, C., Crookenden, M. A., Mitchell, M. D., Loor, J. J., Roche, J. R. & Heiser, A., Mar 1 2016, In : Journal of Dairy Science. 99, 3, p. 2329-2338 10 p.

Research output: Contribution to journalArticle

Immunocompetence
feeding level
Energy Intake
body condition
calving

Immunometabolic status during the peripartum period is enhanced with supplemental Zn, Mn, and Cu from amino acid complexes and Co from Co glucoheptonate

Batistel, F., Osorio, J. S., Ferrari, A., Trevisi, E., Socha, M. T. & Loor, J. J., May 2016, In : PloS one. 11, 5, e0155804.

Research output: Contribution to journalArticle

Peripartum Period
Nutrition
Liver
Diet
Trace Elements
2015

Adipocyte differentiation-related protein promotes lipid accumulation in goat mammary epithelial cells

Shi, H. B., Yu, K., Luo, J., Li, J., Tian, H. B., Zhu, J. J., Sun, Y. T., Yao, D. W., Xu, H. F., Shi, H. P. & Loor, J. J., Oct 1 2015, In : Journal of Dairy Science. 98, 10, p. 6954-6964 11 p., 73830.

Research output: Contribution to journalArticle

adipocytes
Adipocytes
Goats
breasts
Breast
2017

Grain challenge affects systemic and hepatic molecular biomarkers of inflammation, stress, and metabolic responses to a greater extent in Holstein than Jersey cows

Xu, T., Cardoso, F., Pineda, A., Trevisi, E., Shen, X., Rosa, F., Osorio, J. S. & Loor, J. J., Nov 2017, In : Journal of Dairy Science. 100, 11, p. 9153-9162 10 p.

Research output: Contribution to journalArticle

TOR Serine-Threonine Kinases
Physiological Stress
Jersey
biomarkers
Holstein
2019

Dietary N -carbamylglutamate and l-arginine supplementation improves intestinal energy status in intrauterine-growth-retarded suckling lambs

Zhang, H., Peng, A., Guo, S., Wang, M., Loor, J. J. & Wang, H., Apr 2019, In : Food and Function. 10, 4, p. 1903-1914 12 p.

Research output: Contribution to journalArticle

suckling
arginine
Arginine
lambs
energy
2018

Fertility and the transition dairy cow

Roche, J. R., Burke, C. R., Crookenden, M. A., Heiser, A., Loor, J. J., Meier, S., Mitchell, M. D., Phyn, C. V. C. & Turner, S. A., Jan 1 2018, In : Reproduction, Fertility and Development. 30, 1, p. 85-100 16 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Lactation
Minerals
Fertility
dairy cows
2017

Application of nutrigenomics in small ruminants: Lactation, growth, and beyond

Osorio, J. S., Vailati-Riboni, M., Palladino, A., Luo, J. & Loor, J. J., Sep 2017, In : Small Ruminant Research. 154, p. 29-44 16 p.

Research output: Contribution to journalReview article

Nutrigenomics
nutrigenomics
Ruminants
small ruminants
Lactation
2016

Transcriptome-Wide Analysis Reveals the Role of PPAR γ Controlling the Lipid Metabolism in Goat Mammary Epithelial Cells

Shi, H., Zhao, W., Zhang, C., Shahzad, K., Luo, J. & Loor, J. J., Jan 1 2016, In : PPAR Research. 2016, 9195680.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Gene Expression Profiling
Lipid Metabolism
Goats
Breast
2017

Nuclear receptor subfamily 1 group H member 2 (LXRB) is the predominant liver X receptor subtype regulating transcription of 2 major lipogenic genes in goat primary mammary epithelial cells

Shi, H. B., Zhang, C. H., Xu, Z. A., Xu, X. F., Lv, Z. B., Luo, J. & Loor, J. J., Aug 2017, In : Journal of Dairy Science. 100, 8, p. 6743-6752 10 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Fatty Acid Synthases
major genes
fatty-acid synthase
Goats