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  • Jie Chen
2018

Effects of rapamycin on growth hormone receptor knockout mice

Fang, Y., Hill, C. M., Darcy, J., Reyes-Ordoñez, A., Arauz, E., McFadden, S., Zhang, C., Osland, J., Gao, J., Zhang, T., Frank, S. J., Javors, M. A., Yuan, R., Kopchick, J. J., Sun, L. Y., Chen, J. & Bartke, A., Feb 13 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. E1495-E1503

Research output: Contribution to journalArticle

2014

Stoichiometry and assembly of mTOR complexes revealed by single-molecule pulldown

Jain, A., Arauz, E., Aggarwal, V., Ikon, N., Chen, J. & Ha, T., Dec 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 50, p. 17833-17838 6 p.

Research output: Contribution to journalArticle

2018

Mutually inhibitory Ras-PI(3,4)P2 feedback loops mediate cell migration

Li, X., Edwards, M., Swaney, K. F., Singh, N., Bhattacharya, S., Borleis, J., Long, Y., Iglesias, P. A., Chen, J. & Devreotes, P. N., Sep 25 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 39, p. E9125-E9134

Research output: Contribution to journalArticle

Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation

Dutta, D., Lai, K. Y., Reyes-Ordoñez, A., Chen, J. & van der Donk, W. A., Jan 1 2018, In : Journal of Lipid Research. 59, 8, p. 1433-1445 13 p.

Research output: Contribution to journalArticle

Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1

Kim, I. J., Lee, J., Oh, S. J., Yoon, M. S., Jang, S. S., Holland, R. L., Reno, M. L., Hamad, M. N., Maeda, T., Chung, H. J., Chen, J. & Blanke, S. R., May 9 2018, In : Cell Host and Microbe. 23, 5, p. 583-593.e8

Research output: Contribution to journalArticle

2016

Single-Molecule Analysis of Lipid-Protein Interactions in Crude Cell Lysates

Arauz, E., Aggarwal, V., Jain, A., Ha, T. & Chen, J., May 3 2016, In : Analytical chemistry. 88, 8, p. 4269-4276 8 p.

Research output: Contribution to journalArticle

2015

Rapid mitogenic regulation of the mTORC1 Inhibitor, DEPTOR, by phosphatidic acid

Yoon, M. S., Rosenberger, C. L., Wu, C., Truong, N., Sweedler, J. V. & Chen, J., May 7 2015, In : Molecular cell. 58, 3, p. 549-556 8 p.

Research output: Contribution to journalArticle

2017

LanCL proteins are not Involved in Lanthionine Synthesis in Mammals

He, C., Zeng, M., Dutta, D., Koh, T. H., Chen, J. & Van Der Donk, W. A., Jan 20 2017, In : Scientific reports. 7, 40980.

Research output: Contribution to journalArticle

2019

Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole-body homeostasis

Zhang, Q., Duplany, A., Moncollin, V., Mouradian, S., Goillot, E., Mazelin, L., Gauthier, K., Streichenberger, N., Angleraux, C., Chen, J., Ding, S., Schaeffer, L. & Gangloff, Y. G., Feb 2019, In : Journal of Cachexia, Sarcopenia and Muscle. 10, 1, p. 35-53 19 p.

Research output: Contribution to journalArticle

2014

Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax

Fang, X., Nevo, E., Han, L., Levanon, E. Y., Zhao, J., Avivi, A., Larkin, D., Jiang, X., Feranchuk, S., Zhu, Y., Fishman, A., Feng, Y., Sher, N., Xiong, Z., Hankeln, T., Huang, Z., Gorbunova, V., Zhang, L., Zhao, W., Wildman, D. E. & 33 others, Xiong, Y., Gudkov, A., Zheng, Q., Rechavi, G., Liu, S., Bazak, L., Chen, J., Knisbacher, B. A., Lu, Y., Shams, I., Gajda, K., Farré, M., Kim, J., Lewin, H. A., Ma, J., Band, M., Bicker, A., Kranz, A., Mattheus, T., Schmidt, H., Seluanov, A., Azpurua, J., McGowen, M. R., Ben Jacob, E., Li, K., Peng, S., Zhu, X., Liao, X., Li, S., Krogh, A., Zhou, X., Brodsky, L. & Wang, J., Jun 3 2014, In : Nature communications. 5, 3966.

Research output: Contribution to journalArticle

MicroRNA-146b promotes myogenic differentiation and modulates multiple gene targets in muscle cells

Khanna, N., Ge, Y. & Chen, J., Jun 23 2014, In : PloS one. 9, 6, e100657.

Research output: Contribution to journalArticle

2019

Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration

Son, K., You, J. S., Yoon, M. S., Dai, C., Kim, J. H., Khanna, N., Banerjee, A., Martinis, S. A., Han, G., Han, J. M., Kim, S. & Chen, J., May 1 2019, In : Journal of Clinical Investigation. 129, 5, p. 2088-2093 6 p.

Research output: Contribution to journalArticle

Open Access

Lentivirus-mediated RNAi in skeletal myogenesis

Kim, D., Reyes-Ordoñez, A. & Chen, J., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 95-110 16 p. (Methods in Molecular Biology; vol. 1889).

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt

Zeng, M., Van Der Donk, W. A. & Chen, J., Dec 1 2014, In : Molecular biology of the cell. 25, 24, p. 3954-3961 8 p.

Research output: Contribution to journalArticle

2020

Muscle-derived TRAIL negatively regulates myogenic differentiation

Kim, D., Singh, N., Waldemer-Streyer, R. J., Yoon, M. S. & Chen, J., Sep 1 2020, In : Experimental Cell Research. 394, 1, 112165.

Research output: Contribution to journalArticle

2018

To Grow or Not to Grow: TOR and SnRK2 Coordinate Growth and Stress Response in Arabidopsis

Rosenberger, C. L. & Chen, J., Jan 4 2018, In : Molecular cell. 69, 1, p. 3-4 2 p.

Research output: Contribution to journalShort survey

2017

α7β1 integrin regulation of gene transcription in skeletal muscle following an acute bout of eccentric exercise

Mahmassani, Z. S., Son, K., Pincu, Y., Munroe, M., Drnevich, J., Chen, J. & Boppart, M. D., May 11 2017, In : American Journal of Physiology - Cell Physiology. 312, 5, p. 638-650 13 p.

Research output: Contribution to journalArticle

2016

Leucyl-tRNA Synthetase Activates Vps34 in Amino Acid-Sensing mTORC1 Signaling

Yoon, M. S., Son, K., Arauz, E., Han, J. M., Kim, S. & Chen, J., Aug 9 2016, In : Cell Reports. 16, 6, p. 1510-1517 8 p.

Research output: Contribution to journalArticle

2017

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice

Arif, A., Terenzi, F., Potdar, A. A., Jia, J., Sacks, J., China, A., Halawani, D., Vasu, K., Li, X., Brown, J. M., Chen, J., Kozma, S. C., Thomas, G. & Fox, P. L., Feb 16 2017, In : Nature. 542, 7641, p. 357-361 5 p.

Research output: Contribution to journalArticle