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• 2012

  Mechanistic diversity in the RuBisCO superfamily: RuBisCO from rhodospirillum rubrum is not promiscuous for reactions catalyzed by RuBisCO-like proteins

  Warlick, B. P. E., Imker, H. J., Sriram, J., Tabita, F. R. & Gerlt, J. A., Nov 27 2012, In: Biochemistry. 51, 47, p. 9470-9479 10 p.

  Research output: Contribution to journal › Article › peer-review
• 2003

  Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression

  Harrington, W. R., Sheng, S., Barnett, D. H., Petz, L. N., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Aug 29 2003, In: Molecular and Cellular Endocrinology. 206, 1-2, p. 13-22 10 p.

  Research output: Contribution to journal › Article › peer-review
• 1996

  Mechanism of the reaction catalyzed by mandelate racemase: Structure and mechanistic properties of the D270N mutant

  Schafer, S. L., Barrett, W. C., Kallarakal, A. T., Mitra, B., Kozarich, J. W., Gerlt, J. A., Clifton, J. G., Petsko, G. A. & Kenyon, G. L., May 7 1996, In: Biochemistry. 35, 18, p. 5662-5669 8 p.

  Research output: Contribution to journal › Article › peer-review
• 1991

  Structure of thialysine hydrochloride.

  Ammon, H. L., Prasad, S. M. & Gerlt, J. A., Jul 15 1991, In: Acta crystallographica. Section C, Crystal structure communications. 47 ( Pt 7), p. 1476-1478 3 p.

  Research output: Contribution to journal › Article › peer-review
• 1983

  17O NMR Spectral Properties of Pyrophosphate, Simple Phosphonates, and Thiophosphate and Phosphonate Analogues of ATP

  Gerlt, J. A., Reynolds, M. A., Demou, P. C. & Kenyon, G. L., Oct 1983, In: Journal of the American Chemical Society. 105, 21, p. 6469-6475 7 p.

  Research output: Contribution to journal › Article › peer-review
• 1984

  Estrogen receptor transformation in MCF-7 breast cancer cells: Characterization by immunochemical and sedimentation analyses

  Miller, M. A., Greene, G. L. & Katzenellenbogen, B. S., 1984, In: Endocrinology. 114, 1, p. 296-298 3 p.

  Research output: Contribution to journal › Article › peer-review
• 2012

  A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis

  Erb, T. J., Evans, B. S., Cho, K., Warlick, B. P., Sriram, J., Wood, B. M. K., Imker, H. J., Sweedler, J. V., Tabita, F. R. & Gerlt, J. A., Nov 2012, In: Nature chemical biology. 8, 11, p. 926-932 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2009

  Acetoacetate decarboxylase: Hydrophobics, not electrostatics

  Gerlt, J. A., Jul 2009, In: Nature chemical biology. 5, 7, p. 454-455 2 p.

  Research output: Contribution to journal › Short survey › peer-review

• Enzyme (re)design: lessons from natural evolution and computation

  Gerlt, J. A. & Babbitt, P. C., Feb 2009, In: Current Opinion in Chemical Biology. 13, 1, p. 10-18 9 p.

  Research output: Contribution to journal › Review article › peer-review
• 1981

  Additions and Corrections: The Solution Conformational Preferences of the Sugar and Sugar Phosphate Constituents of RNA and DNA (Journal of the American Chemical Society (1980) 103(25) (7433–7438))

  Gerlt, J. A. & Youngblood, A. V., Jun 1981, In: Journal of the American Chemical Society. 103, 12, 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• 1993

  Membrane proteins. Current Opinion in Structural Biology 1993, 3:499-500

  Gennis, R. B. & Kühlbrandt, W., Aug 1993, In: Current Opinion in Structural Biology. 3, 4, p. 499-500 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• 1984

  Identification of subunit I as the cytochrome b₅₅₈ component of the cytochrome d terminal oxidase complex of Escherichia coli

  Green, G. N., Kranz, R. G., Lorence, R. M. & Gennis, R. B., 1984, In: Journal of Biological Chemistry. 259, 12, p. 7994-7997 4 p.

  Research output: Contribution to journal › Article › peer-review
• 2006

  Metabolite ligands of estrogen receptor-β reduce primate coronary hyperreactivity

  Mishra, R. G., Stanczyk, F. Z., Burry, K. A., Oparil, S., Katzenellenbogen, B. S., Nealen, M. L., Katzenellenbogen, J. A. & Hermsmeyer, R. K., Jan 2006, In: American Journal of Physiology - Heart and Circulatory Physiology. 290, 1, p. H295-H303

  Research output: Contribution to journal › Article › peer-review
• 2005

  G204D, a mutation that blocks the proton-conducting D-channel of the aa₃-type cytochrome c oxidase from Rhodobacter sphaeroides

  Han, D., Morgan, J. E. & Gennis, R. B., Sep 27 2005, In: Biochemistry. 44, 38, p. 12767-12774 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2001

  Human estrogen receptor beta-specific monoclonal antibodies: Characterization and use in studies of estrogen receptor beta protein expression in reproductive tissues

  Choi, I., Ko, C., Park-Sarge, O. K., Nie, R., Hess, R. A., Graves, C. & Katzenellenbogen, B. S., Jul 5 2001, In: Molecular and Cellular Endocrinology. 181, 1-2, p. 139-150 12 p.

  Research output: Contribution to journal › Article › peer-review
• 1980

  Dynamics of steroid hormone receptor action

  Katzenellenbogen, B. S., Jan 1 1980, In: Annual review of physiology. Vol. 42, p. 17-35 19 p.

  Research output: Contribution to journal › Article › peer-review
• 2021

  Energy transfer between the nicotinamide nucleotide transhydrogenase and ATP synthase of Escherichia coli

  Graf, S. S., Hong, S., Müller, P., Gennis, R. & von Ballmoos, C., Dec 2021, In: Scientific reports. 11, 1, 21234.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 1982

  Proximity of Reactive Cysteine Residue and Flavin in Escherichia coli Pyruvate Oxidase As Estimated by Fluorescence Energy Transfer

  Koland, J. G. & Gennis, R. B., Aug 1982, In: Biochemistry. 21, 18, p. 4438-4442 5 p.

  Research output: Contribution to journal › Article › peer-review
• 1994

  Identification of the ubiquinol-binding site in the cytochrome bo₃- ubiquinol oxidase of Escherichia coli

  Welter, R., Gu, L. Q., Yu, L., Yu, C. A., Rumbley, J. & Gennis, R. B., 1994, In: Journal of Biological Chemistry. 269, 46, p. 28834-28838 5 p.

  Research output: Contribution to journal › Article › peer-review

• A Loop between Transmembrane Helices IX and X of Subunit I of Cytochrome c Oxidase Caps the Heme a-Heme a₃-Cu_B Center

  Hosler, J. P., Shapleigh, J. P., Tecklenburg, M. M. J., Thomas, J. W., Kim, Y., Espe, M., Fetter, J., Babcock, G. T., Alben, J. O., Gennis, R. B. & Ferguson-Miller, S., Feb 1 1994, In: Biochemistry. 33, 5, p. 1194-1201 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2002

  Activation volumes for intramolecular electron transfer in Escherichia coli cytochrome bo₃

  Ching, E., Gennis, R. B. & Larsen, R. W., Sep 11 2002, In: FEBS Letters. 527, 1-3, p. 81-85 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2001

  ph-dependent structural changes at the heme-copper binuclear center of cytochrome c oxidase

  Das, T. K., Tomson, F. L., Gennis, R. B., Gordon, M. & Rousseau, D. L., 2001, In: Biophysical journal. 80, 5, p. 2039-2045 7 p.

  Research output: Contribution to journal › Article › peer-review
• 1990

  Kinetic and Conformational Effects of Lysine Substitutions for Arginines 35 and 87 in the Active Site of Staphylococcal Nuclease

  Pourmotabbed, T., Dell’Acqua, M., Gerlt, J. A., Stanczyk, S. M. & Bolton, P. H., Apr 1 1990, In: Biochemistry. 29, 15, p. 3677-3683 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2000

  Evolution of enzymatic activities in the enolase superfamily: Crystallographic and mutagenesis studies of the reaction catalyzed by D- glucarate dehydratase from Escherichia coli

  Gulick, A. M., Hubbard, B. K., Gerlt, J. A. & Rayment, I., Apr 25 2000, In: Biochemistry. 39, 16, p. 4590-4602 13 p.

  Research output: Contribution to journal › Article › peer-review
• 2001

  Evolution of enzymatic activities in the enolase superfamily: Functional assignment of unknown proteins in bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases

  Schmidt, D. M. Z., Hubbard, B. K. & Gerlt, J. A., Dec 25 2001, In: Biochemistry. 40, 51, p. 15707-15715 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2000

  Discovering new enzymes and metabolic pathways: Conversion of succinate to propionate by Escherichia coli

  Haller, T., Buckel, T., Rétey, J. & Gerlt, J. A., Apr 25 2000, In: Biochemistry. 39, 16, p. 4622-4629 8 p.

  Research output: Contribution to journal › Article › peer-review
• 1991

  Mechanism of the Reaction Catalyzed by Mandelate Racemase. 3. Asymmetry in Reactions Catalyzed by the H297N Mutant

  Landro, J. A., Kallarakal, A. T., Ransom, S. C., Gerlt, J. A., Kozarich, J. W., Neidhart, D. J. & Kenyon, G. L., Sep 1 1991, In: Biochemistry. 30, 38, p. 9274-9281 8 p.

  Research output: Contribution to journal › Article › peer-review
• 1993

  An explanation for rapid enzyme-catalyzed proton abstraction from carbon acids: Importance of late transition states in concerted mechanisms

  Gerlt, J. A. & Gassman, P. G., Jan 1 1993, In: Journal of the American Chemical Society. 115, 24, p. 11552-11568 17 p.

  Research output: Contribution to journal › Article › peer-review
• 2015

  Enzyme function initiative-enzyme similarity tool (EFI-EST): A web tool for generating protein sequence similarity networks

  Gerlt, J. A., Bouvier, J. T., Davidson, D. B., Imker, H. J., Sadkhin, B., Slater, D. R. & Whalen, K. L., Aug 1 2015, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1854, 8, p. 1019-1037 19 p.

  Research output: Contribution to journal › Review article › peer-review
• 2014

  Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

  Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In: mBio. 5, 1, e00933-13.

  Research output: Contribution to journal › Article › peer-review
• 2001

  Divergent evolution of enzymatic function: Mechanistically diverse superfamilies and functionally distinct suprafamilies

  Gerlt, J. A. & Babbitt, P. C., Jul 30 2001, In: Annual review of biochemistry. 70, p. 209-246 38 p.

  Research output: Contribution to journal › Review article › peer-review
• 1992

  Phosphate Ester Hydrolysis

  Gerlt, J. A., Jan 1 1992, In: Enzymes. 20, C, p. 95-139 45 p.

  Research output: Contribution to journal › Article › peer-review
• 1996

  Evolution of enzymatic activities: Multiple pathways for generating and partitioning a common enolic intermediate by glucarate dehydratase from Pseudomonas putida

  Palmer, D. R. J. & Gerlt, J. A., Oct 23 1996, In: Journal of the American Chemical Society. 118, 42, p. 10323-10324 2 p.

  Research output: Contribution to journal › Article › peer-review
• 1973

  A Phosphodiesterase from Enterobacter aerogenes

  Gerlt, J. A. & Westheimer, F. H., Nov 1 1973, In: Journal of the American Chemical Society. 95, 24, p. 8166-8168 3 p.

  Research output: Contribution to journal › Letter › peer-review
• 1988

  Comparative analysis of estrogen receptors covalently labeled with an estrogen and an antiestrogen in several estrogen target cells as studied by limited proteolysis

  Elliston, J. F. & Katzenellenbogen, B. S., Jun 1988, In: Journal of Steroid Biochemistry. 29, 6, p. 559-569 11 p.

  Research output: Contribution to journal › Article › peer-review
• 1985

  Succinate dehydrogenase in Rhodopseudomonas sphaeroides: Subunit composition and immunocross-reactivity with other related bacteria

  Barassi, C. A., Kranz, R. G. & Gennis, R. B., 1985, In: Journal of bacteriology. 163, 2, p. 778-782 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  Estrogen-regulated gene networks in human breast cancer cells: Involvement of E2F1 in the regulation of cell proliferation

  Stender, J. D., Frasor, J., Komm, B., Chang, K. C. N., Kraus, W. L. & Katzenellenbogen, B. S., Sep 2007, In: Molecular Endocrinology. 21, 9, p. 2112-2123 12 p.

  Research output: Contribution to journal › Article › peer-review
• 1993

  Spectroscopic evidence for a heme-heme binuclear center in the cytochrome bd ubiquinol oxidase from Escherichia coli

  Hill, J. J., Alben, J. O. & Gennis, R. B., Jun 15 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 12, p. 5863-5867 5 p.

  Research output: Contribution to journal › Article › peer-review
• 1986

  Spectroscopic studies on heme d in the visible and infrared

  Vavra, M. R., Timkovich, R., Yap, F. & Gennis, R. B., Nov 1 1986, In: Archives of Biochemistry and Biophysics. 250, 2, p. 461-468 8 p.

  Research output: Contribution to journal › Article › peer-review
• 1992

  Characterization and regulation of estrogen and progesterone receptors in breast cancer.

  Read, L. D. & Katzenellenbogen, B. S., Dec 1 1992, In: Cancer treatment and research. 61, p. 277-299 23 p.

  Research output: Contribution to journal › Article › peer-review
• 1993

  Regulation of progesterone receptor gene expression and growth in the rat uterus: Modulation of estrogen actions by progesterone and sex steroid hormone antagonists

  Lee Kraus, W. & Katzenellenbogen, B. S., Jun 1993, In: Endocrinology. 132, 6, p. 2371-2379 9 p.

  Research output: Contribution to journal › Article › peer-review
• 1998

  Determinants of ligand specificity of estrogen receptor-α: Estrogen versus androgen discrimination

  Ekena, K., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 9 1998, In: Journal of Biological Chemistry. 273, 2, p. 693-699 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2005

  Photothermal studies of CO photodissociation from mixed valence Escherichia coli cytochrome bo₃

  Mikšovská, J., Gennis, R. B. & Larsen, R. W., Jun 6 2005, In: FEBS Letters. 579, 14, p. 3014-3018 5 p.

  Research output: Contribution to journal › Article › peer-review
• 1996

  Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones

  Katzenellenbogen, J. A., O'Malley, B. W. & Katzenellenbogen, B. S., Feb 13 1996, In: Molecular Endocrinology. 10, 2, p. 119-131 13 p.

  Research output: Contribution to journal › Short survey › peer-review
• 2004

  Allosteric Control of Ligand Selectivity between Estrogen Receptors α and β: Implications for Other Nuclear Receptors

  Nettles, K. W., Sun, J., Radek, J. T., Sheng, S., Rodriguez, A. L., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Greene, G. L., Feb 13 2004, In: Molecular cell. 13, 3, p. 317-327 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2009

  Mechanism of the orotidine 5′-monophosphate decarboxylase-catalyzed reaction: Evidence for substrate destabilization

  Chan, K. K., Wood, B. M. K., Fedorov, A. A., Fedorov, E. V., Imker, H. J., Amyes, T. L., Richard, J. P., Almo, S. C. & Gerlt, J. A., Jun 23 2009, In: Biochemistry. 48, 24, p. 5518-5531 14 p.

  Research output: Contribution to journal › Article › peer-review
• 2013

  Computational, structural, and kinetic evidence that Vibrio vulnificus FrsA is not a cofactor-independent pyruvate decarboxylase

  Kellett, W. F., Brunk, E., Desai, B. J., Fedorov, A. A., Almo, S. C., Gerlt, J. A., Rothlisberger, U. & Richards, N. G. J., Mar 19 2013, In: Biochemistry. 52, 11, p. 1842-1844 3 p.

  Research output: Contribution to journal › Article › peer-review
• 2018

  Enzyme Architecture: Breaking Down the Catalytic Cage that Activates Orotidine 5′-Monophosphate Decarboxylase for Catalysis

  Reyes, A. C., Plache, D. C., Koudelka, A. P., Amyes, T. L., Gerlt, J. A. & Richard, J. P., Dec 19 2018, In: Journal of the American Chemical Society. 140, 50, p. 17580-17590 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 1998

  Structure and mechanism of benzoylformate decarboxylase, a thiamin dtthosphate-dependent enzyme

  Kenvon, Q. L., Hasson, M. S., Muscate, A., McLeish, M. J., Harris, T. K., Babbitt, P. Ç., Gerlt, J. A., Petsko, G. A. & Rinye, D., Dec 1 1998, In: FASEB Journal. 12, 8, p. A1332

  Research output: Contribution to journal › Article › peer-review
• 1980

  Conformational Properties of 5-Alkoxy and 5-Alkyl Substituted Trimethylene Phosphates in Solution

  Gerlt, J. A., Gutterson, N. I., Drews, R. E. & Sokolow, J. A., Feb 1980, In: Journal of the American Chemical Society. 102, 5, p. 1665-1670 6 p.

  Research output: Contribution to journal › Article › peer-review