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Author

  • Jie Chen
2013

Duration of rapamycin treatment has differential effects on metabolism in mice

Fang, Y., Westbrook, R., Hill, C., Boparai, R. K., Arum, O., Spong, A., Wang, F., Javors, M. A., Chen, J., Sun, L. Y. & Bartke, A., Mar 5 2013, In : Cell Metabolism. 17, 3, p. 456-462 7 p.

Research output: Contribution to journalArticle

2015

Rapid mitogenic regulation of the mTORC1 Inhibitor, DEPTOR, by phosphatidic acid

Yoon, M. S., Rosenberger, C. L., Wu, C., Truong, N., Sweedler, J. V. & Chen, J., May 7 2015, In : Molecular cell. 58, 3, p. 549-556 8 p.

Research output: Contribution to journalArticle

2012

Mammalian target of rapamycin (mTOR) signaling network in skeletal myogenesis

Ge, Y. & Chen, J., Dec 21 2012, In : Journal of Biological Chemistry. 287, 52, p. 43928-43935 8 p.

Research output: Contribution to journalShort survey

2019

Lentivirus-mediated RNAi in skeletal myogenesis

Kim, D., Reyes-Ordoñez, A. & Chen, J., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 95-110 16 p. (Methods in Molecular Biology; vol. 1889).

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

α7β1 integrin regulation of gene transcription in skeletal muscle following an acute bout of eccentric exercise

Mahmassani, Z. S., Son, K., Pincu, Y., Munroe, M., Drnevich, J., Chen, J. & Boppart, M. D., May 11 2017, In : American Journal of Physiology - Cell Physiology. 312, 5, p. 638-650 13 p.

Research output: Contribution to journalArticle

2013

XPLN is an endogenous inhibitor of mTORC2

Khanna, N., Fang, Y., Yoon, M. S. & Chen, J., Oct 1 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. 15979-15984 6 p.

Research output: Contribution to journalArticle

2012

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

Sun, Z., Miller, R. A., Patel, R. T., Chen, J., Dhir, R., Wang, H., Zhang, D., Graham, M. J., Unterman, T. G., Shulman, G. I., Sztalryd, C., Bennett, M. J., Ahima, R. S., Birnbaum, M. J. & Lazar, M. A., Jun 1 2012, In : Nature Medicine. 18, 6, p. 934-942 9 p.

Research output: Contribution to journalArticle

2019

Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole-body homeostasis

Zhang, Q., Duplany, A., Moncollin, V., Mouradian, S., Goillot, E., Mazelin, L., Gauthier, K., Streichenberger, N., Angleraux, C., Chen, J., Ding, S., Schaeffer, L. & Gangloff, Y. G., Feb 2019, In : Journal of Cachexia, Sarcopenia and Muscle. 10, 1, p. 35-53 19 p.

Research output: Contribution to journalArticle

2013

Distinct amino acid-sensing mTOR pathways regulate skeletal myogenesis

Yoon, M. S. & Chen, J., Dec 1 2013, In : Molecular biology of the cell. 24, 23, p. 3754-3763 10 p.

Research output: Contribution to journalArticle

RNAi Screen Reveals Potentially Novel Roles of Cytokines in Myoblast Differentiation

Ge, Y., Waldemer, R. J., Nalluri, R., Nuzzi, P. D. & Chen, J., Jul 2 2013, In : PloS one. 8, 7, e68068.

Research output: Contribution to journalArticle

2018

Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation

Dutta, D., Lai, K. Y., Reyes-Ordoñez, A., Chen, J. & van der Donk, W. A., Jan 1 2018, In : Journal of Lipid Research. 59, 8, p. 1433-1445 13 p.

Research output: Contribution to journalArticle

2016

Single-Molecule Analysis of Lipid-Protein Interactions in Crude Cell Lysates

Arauz, E., Aggarwal, V., Jain, A., Ha, T. & Chen, J., May 3 2016, In : Analytical chemistry. 88, 8, p. 4269-4276 8 p.

Research output: Contribution to journalArticle

2018

Mutually inhibitory Ras-PI(3,4)P2 feedback loops mediate cell migration

Li, X., Edwards, M., Swaney, K. F., Singh, N., Bhattacharya, S., Borleis, J., Long, Y., Iglesias, P. A., Chen, J. & Devreotes, P. N., Sep 25 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 39, p. E9125-E9134

Research output: Contribution to journalArticle

2012

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling

Zhang, C., Wendel, A. A., Keogh, M. R., Harris, T. E., Chen, J. & Coleman, R. A., Jan 31 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 5, p. 1667-1672 6 p.

Research output: Contribution to journalArticle

2017

LanCL proteins are not Involved in Lanthionine Synthesis in Mammals

He, C., Zeng, M., Dutta, D., Koh, T. H., Chen, J. & Van Der Donk, W. A., Jan 20 2017, In : Scientific reports. 7, 40980.

Research output: Contribution to journalArticle

2018

Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1

Kim, I. J., Lee, J., Oh, S. J., Yoon, M. S., Jang, S. S., Holland, R. L., Reno, M. L., Hamad, M. N., Maeda, T., Chung, H. J., Chen, J. & Blanke, S. R., May 9 2018, In : Cell Host and Microbe. 23, 5, p. 583-593.e8

Research output: Contribution to journalArticle

2017

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice

Arif, A., Terenzi, F., Potdar, A. A., Jia, J., Sacks, J., China, A., Halawani, D., Vasu, K., Li, X., Brown, J. M., Chen, J., Kozma, S. C., Thomas, G. & Fox, P. L., Feb 16 2017, In : Nature. 542, 7641, p. 357-361 5 p.

Research output: Contribution to journalArticle

2019

Nontranslational function of leucyl-tRNA synthetase regulates myogenic differentiation and skeletal muscle regeneration

Son, K., You, J. S., Yoon, M. S., Dai, C., Kim, J. H., Khanna, N., Banerjee, A., Martinis, S. A., Han, G., Han, J. M., Kim, S. & Chen, J., May 1 2019, In : Journal of Clinical Investigation. 129, 5, p. 2088-2093 6 p.

Research output: Contribution to journalArticle

Open Access
2018

To Grow or Not to Grow: TOR and SnRK2 Coordinate Growth and Stress Response in Arabidopsis

Rosenberger, C. L. & Chen, J., Jan 4 2018, In : Molecular cell. 69, 1, p. 3-4 2 p.

Research output: Contribution to journalShort survey

2013

Flt3L is a novel regulator of skeletal myogenesis

Ge, Y., Waldemer, R. J., Nalluri, R., Nuzzi, P. D. & Chen, J., 2013, In : Journal of cell science. 126, 15, p. 3370-3379 10 p.

Research output: Contribution to journalArticle

Mechanistic target of rapamycin controls homeostasis of adipogenesis

Yoon, M. S., Zhang, C., Sun, Y., Schoenherr, C. J. & Chen, J., Aug 1 2013, In : Journal of Lipid Research. 54, 8, p. 2166-2173 8 p.

Research output: Contribution to journalArticle

Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton

He, Y., Li, D., Cook, S. L., Yoon, M. S., Kapoor, A., Rao, C. V., Kenis, P. J. A., Chen, J. & Wang, F., Nov 1 2013, In : Molecular biology of the cell. 24, 21, p. 3369-3380 12 p.

Research output: Contribution to journalArticle

2020

Muscle-derived TRAIL negatively regulates myogenic differentiation

Kim, D., Singh, N., Waldemer-Streyer, R. J., Yoon, M. S. & Chen, J., Sep 1 2020, In : Experimental Cell Research. 394, 1, 112165.

Research output: Contribution to journalArticle

2018

Effects of rapamycin on growth hormone receptor knockout mice

Fang, Y., Hill, C. M., Darcy, J., Reyes-Ordoñez, A., Arauz, E., McFadden, S., Zhang, C., Osland, J., Gao, J., Zhang, T., Frank, S. J., Javors, M. A., Yuan, R., Kopchick, J. J., Sun, L. Y., Chen, J. & Bartke, A., Feb 13 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. E1495-E1503

Research output: Contribution to journalArticle

2016

Leucyl-tRNA Synthetase Activates Vps34 in Amino Acid-Sensing mTORC1 Signaling

Yoon, M. S., Son, K., Arauz, E., Han, J. M., Kim, S. & Chen, J., Aug 9 2016, In : Cell Reports. 16, 6, p. 1510-1517 8 p.

Research output: Contribution to journalArticle