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Author

  • Huimin Zhao
2011

Engineering microbial factories for synthesis of value-added products

Du, J., Shao, Z. & Zhao, H., Aug 2011, In : Journal of Industrial Microbiology and Biotechnology. 38, 8, p. 873-890 18 p.

Research output: Contribution to journalReview article

2019

Towards a fully automated algorithm driven platform for biosystems design

HamediRad, M., Chao, R., Weisberg, S., Lian, J., Sinha, S. & Zhao, H., Nov 13 2019, In : Nature communications. 10, 1, 5150.

Research output: Contribution to journalArticle

Open Access

A pathway for isethionate dissimilation in Bacillus krulwichiae

Tong, Y., Wei, Y., Hu, Y., Ang, E. L., Zhao, H. & Zhang, Y., 2019, In : Applied and environmental microbiology. 85, 15, e00793-19.

Research output: Contribution to journalArticle

2020

Biosynthetic engineering of the antifungal, anti-MRSA auroramycin

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Ching, K. C., Tsai, D. J., Jhang, Y. W., Lauderdale, T. L., Shia, K. S., Zhao, H., Ang, E. L., Zhang, M. M., Lim, Y. H. & Wong, F. T., Jan 6 2020, In : Microbial cell factories. 19, 1, 3.

Research output: Contribution to journalArticle

Open Access
2013

Introduction

Zhao, H., Aug 27 2013, In : Synthetic Biology.

Research output: Contribution to journalArticle

2012

DNA assembler: A synthetic biology tool for characterizing and engineering natural product gene clusters

Shao, Z. & Zhao, H., 2012, Natural Product Biosynthesis by Microorganisms and Plants, Part C. Academic Press Inc., p. 203-224 22 p. (Methods in Enzymology; vol. 517).

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster

Luo, Y., Huang, H., Liang, J., Wang, M., Lu, L., Shao, Z., Cobb, R. E. & Zhao, H., Dec 5 2013, In : Nature communications. 4, 2894.

Research output: Contribution to journalArticle

2011

Combinatorial optimization of a highly efficient xylose utilization pathway in saccharomyces cerevisiae

Du, J., Kim, B. & Zhao, H., Dec 1 2011, 11AIChE - 2011 AIChE Annual Meeting, Conference Proceedings. (11AIChE - 2011 AIChE Annual Meeting, Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2015

Recent advances in DNA assembly technologies

Chao, R., Yuan, Y. & Zhao, H., 2015, In : FEMS yeast research. 15, 1, 12171.

Research output: Contribution to journalShort survey

2014

Engineering chimeric RNA-binding proteins: Modular design, novel function

Abil, Z., Denard, C. A., Hoogenraad, C. & Zhao, H., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, 1 p. (Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2015

Improving and repurposing biocatalysts via directed evolution

Denard, C. A., Ren, H. & Zhao, H., Apr 1 2015, In : Current Opinion in Chemical Biology. 25, p. 55-64 10 p.

Research output: Contribution to journalReview article

2014

Characterization and engineering of the adenylation domain of a NRPS-like protein: A potential biocatalyst for aldehyde generation

Wang, M. & Zhao, H., Apr 4 2014, In : ACS Catalysis. 4, 4, p. 1219-1225 7 p.

Research output: Contribution to journalArticle

2020

Discovery and Characterization of a Class IV Lanthipeptide with a Nonoverlapping Ring Pattern

Ren, H., Shi, C., Bothwell, I. R., Van Der Donk, W. A., Van Der Donk, W. A., Van Der Donk, W. A., Zhao, H., Zhao, H., Zhao, H., Zhao, H. & Zhao, H., Jun 19 2020, In : ACS chemical biology. 15, 6, p. 1642-1649 8 p.

Research output: Contribution to journalArticle

2014

Directed evolution of a cellodextrin transporter for improved biofuel production under anaerobic conditions in Saccharomyces cerevisiae

Lian, J., Li, Y., HamediRad, M. & Zhao, H., Aug 2014, In : Biotechnology and bioengineering. 111, 8, p. 1521-1531 11 p.

Research output: Contribution to journalArticle

2013

Directed evolution: Past, present, and future

Cobb, R. E., Chao, R. & Zhao, H., May 2013, In : AIChE Journal. 59, 5, p. 1432-1440 9 p.

Research output: Contribution to journalArticle

2015

High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System

Cobb, R. E., Wang, Y. & Zhao, H., Jun 19 2015, In : ACS synthetic biology. 4, 6, p. 723-728 6 p.

Research output: Contribution to journalArticle

2011

Cloning and characterization of a type III polyketide synthase from Aspergillus niger

Li, J., Luo, Y., Lee, J. K. & Zhao, H., Oct 15 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 20, p. 6085-6089 5 p.

Research output: Contribution to journalArticle

2018

Pathway design, engineering, and optimization

Garcia-Ruiz, E., HamediRad, M. & Zhao, H., Jan 1 2018, Advances in Biochemical Engineering/Biotechnology. Springer Science and Business Media Deutschland GmbH, (Advances in Biochemical Engineering/Biotechnology; vol. 162).

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Engineering reprogrammable RNA-binding proteins for study and manipulation of the transcriptome

Abil, Z. & Zhao, H., Jul 6 2015, In : Molecular BioSystems. 11, 10, p. 2658-2665 8 p.

Research output: Contribution to journalArticle

2018

In vivo biosensors: mechanisms, development, and applications

Shi, S., Ang, E. L. & Zhao, H., Jul 1 2018, In : Journal of Industrial Microbiology and Biotechnology. 45, 7, p. 491-516 26 p.

Research output: Contribution to journalArticle

2019

Highly Efficient Single-Pot Scarless Golden Gate Assembly

Hamedirad, M., Weisberg, S., Chao, R., Lian, J. & Zhao, H., May 17 2019, In : ACS synthetic biology. 8, 5, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

2020

A New Biosensor for Stilbenes and a Cannabinoid Enabled by Genome Mining of a Transcriptional Regulator

Sun, H., Zhao, H. & Ang, E. L., Apr 17 2020, In : ACS synthetic biology. 9, 4, p. 698-705 8 p.

Research output: Contribution to journalArticle

2015

Regulatory RNA-assisted genome engineering in microorganisms

Si, T., HamediRad, M. & Zhao, H., Dec 1 2015, In : Current Opinion in Biotechnology. 36, p. 85-90 6 p.

Research output: Contribution to journalReview article

2011

New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF

Bae, B., Cobb, R. E., DeSieno, M. A., Zhao, H. & Nair, S. K., Oct 14 2011, In : Journal of Biological Chemistry. 286, 41, p. 36132-36141 10 p.

Research output: Contribution to journalArticle

2020

Emerging molecular biology tools and strategies for engineering natural product biosynthesis

Xu, W., Klumbys, E., Ang, E. L. & Zhao, H., Jun 2020, In : Metabolic Engineering Communications. 10, e00108.

Research output: Contribution to journalReview article

Open Access
2014

A single-chain TALEN architecture for genome engineering

Sun, N. & Zhao, H., Mar 1 2014, In : Molecular BioSystems. 10, 3, p. 446-453 8 p.

Research output: Contribution to journalArticle

2020

Unlocking nature's biosynthetic potential by directed genome evolution

Cao, M., Tran, V. G. & Zhao, H., Dec 2020, In : Current Opinion in Biotechnology. 66, p. 95-104 10 p.

Research output: Contribution to journalReview article

2012

Biocatalyst development by directed evolution

Wang, M., Si, T. & Zhao, H., Jul 2012, In : Bioresource Technology. 115, p. 117-125 9 p.

Research output: Contribution to journalArticle

2020

Towards oilcane: Engineering hyperaccumulation of triacylglycerol into sugarcane stems

Parajuli, S., Kannan, B., Karan, R., Sanahuja, G., Liu, H., Garcia-Ruiz, E., Kumar, D., Singh, V., Zhao, H., Long, S., Shanklin, J. & Altpeter, F., Jul 1 2020, In : GCB Bioenergy. 12, 7, p. 476-490 15 p.

Research output: Contribution to journalArticle

Open Access
2017

A plug-and-play pathway refactoring workflow for natural product research in Escherichia coli and Saccharomyces cerevisiae

Ren, H., Hu, P. & Zhao, H., Aug 2017, In : Biotechnology and bioengineering. 114, 8, p. 1847-1854 8 p.

Research output: Contribution to journalArticle

2015

High throughput screening and selection methods for directed enzyme evolution

Xiao, H., Bao, Z. & Zhao, H., Apr 29 2015, In : Industrial and Engineering Chemistry Research. 54, 16, p. 4011-4020 10 p.

Research output: Contribution to journalArticle

Rapid prototyping of microbial cell factories via genome-scale engineering

Si, T., Xiao, H. & Zhao, H., Nov 15 2015, In : Biotechnology Advances. 33, 7, p. 1420-1432 13 p.

Research output: Contribution to journalReview article

2013

Modular assembly of designer Puf proteins for specific post-transcriptional regulation of endogenous RNA

Abil, Z. & Zhao, H., Jan 1 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, 1 p. (Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2019

Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Lim, Y. H., Hoon, S., Zhao, H., Zhang, M. M. & Wong, F. T., 2019, In : Biotechnology and bioengineering. 116, 9, p. 2330-2338 9 p.

Research output: Contribution to journalArticle

2018
2017

Breaking the silence: new strategies for discovering novel natural products

Ren, H., Wang, B. & Zhao, H., Dec 1 2017, In : Current Opinion in Biotechnology. 48, p. 21-27 7 p.

Research output: Contribution to journalReview article

2014

Design and construction of acetyl-CoA overproducing Saccharomyces cerevisiae strains

Lian, J., Si, T., Nair, N. U. & Zhao, H., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, p. 750-760 11 p. (Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2020

A Pathway for Degradation of Uracil to Acetyl Coenzyme A in Bacillus megaterium

Zhu, D., Wei, Y., Yin, J., Liu, D., Ang, E. L., Zhao, H. & Zhang, Y., Mar 18 2020, In : Applied and environmental microbiology. 86, 7

Research output: Contribution to journalArticle

2011

A new fluorescence complementation biosensor for detection of estrogenic compounds

Mclachlan, M. J., Katzenellenbogen, J. A. & Zhao, H., Dec 2011, In : Biotechnology and bioengineering. 108, 12, p. 2794-2803 10 p.

Research output: Contribution to journalArticle

2017

Probing the molecular determinants of fluorinase specificity

Yeo, W. L., Chew, X., Smith, D. J., Chan, K. P., Sun, H., Zhao, H., Lim, Y. H. & Ang, E. L., Jan 1 2017, In : Chemical Communications. 53, 17, p. 2559-2562 4 p.

Research output: Contribution to journalArticle

2018

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

Lian, J., HamediRad, M. & Zhao, H., Sep 2018, In : Biotechnology Journal. 13, 9, 1700601.

Research output: Contribution to journalReview article

2012

Role of conserved glycine in zinc-dependent medium chain dehydrogenase/reductase superfamily

Tiwari, M. K., Singh, R. K., Singh, R., Jeya, M., Zhao, H. & Lee, J. K., Jun 1 2012, In : Journal of Biological Chemistry. 287, 23, p. 19429-19439 11 p.

Research output: Contribution to journalArticle

2019

A continuing career in biocatalysis: Frances H. Arnold

Fasan, R., Jennifer Kan, S. B. & Zhao, H., Nov 1 2019, In : ACS Catalysis. 9, 11, p. 9775-9788 14 p.

Research output: Contribution to journalArticle

Biochemical and structural investigation of sulfoacetaldehyde reductase from Klebsiella oxytoca

Zhou, Y., Wei, Y., Lin, L., Xu, T., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jan 1 2019, In : Biochemical Journal. 476, 4, p. 733-746 14 p.

Research output: Contribution to journalArticle

2020

Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate

Liu, J., Wei, Y., Lin, L., Teng, L., Yin, J., Lu, Q., Chen, J., Zheng, Y., Li, Y., Xu, R., Zhai, W., Liu, Y., Liu, Y., Cao, P., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jul 7 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 27, p. 15599-155608 140010 p.

Research output: Contribution to journalArticle

2014

Utilizing an endogenous pathway for 1-butanol production in Saccharomyces cerevisiae

Si, T., Luo, Y., Xiao, H. & Zhao, H., Mar 1 2014, In : Metabolic Engineering. 22, p. 60-68 9 p.

Research output: Contribution to journalArticle

Protein design for pathway engineering

Eriksen, D. T., Lian, J. & Zhao, H., Feb 2014, In : Journal of Structural Biology. 185, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

2020

Integrating biocatalysis with chemocatalysis for selective transformations

Huang, X., Cao, M. & Zhao, H., Apr 2020, In : Current Opinion in Chemical Biology. 55, p. 161-170 10 p.

Research output: Contribution to journalReview article