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  • Huimin Zhao
2019

Highly Efficient Single-Pot Scarless Golden Gate Assembly

Hamedirad, M., Weisberg, S., Chao, R., Lian, J. & Zhao, H., May 17 2019, In : ACS synthetic biology. 8, 5, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

2018

In vivo biosensors: mechanisms, development, and applications

Shi, S., Ang, E. L. & Zhao, H., Jul 1 2018, In : Journal of Industrial Microbiology and Biotechnology. 45, 7, p. 491-516 26 p.

Research output: Contribution to journalArticle

2011

New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF

Bae, B., Cobb, R. E., DeSieno, M. A., Zhao, H. & Nair, S. K., Oct 14 2011, In : Journal of Biological Chemistry. 286, 41, p. 36132-36141 10 p.

Research output: Contribution to journalArticle

2014

A single-chain TALEN architecture for genome engineering

Sun, N. & Zhao, H., Mar 1 2014, In : Molecular BioSystems. 10, 3, p. 446-453 8 p.

Research output: Contribution to journalArticle

2015

Engineering reprogrammable RNA-binding proteins for study and manipulation of the transcriptome

Abil, Z. & Zhao, H., Jul 6 2015, In : Molecular BioSystems. 11, 10, p. 2658-2665 8 p.

Research output: Contribution to journalArticle

2017

Probing the molecular determinants of fluorinase specificity

Yeo, W. L., Chew, X., Smith, D. J., Chan, K. P., Sun, H., Zhao, H., Lim, Y. H. & Ang, E. L., Jan 1 2017, In : Chemical Communications. 53, 17, p. 2559-2562 4 p.

Research output: Contribution to journalArticle

2016
2010

Crystal structure and computational analyses provide insights into the catalytic mechanism of 2,4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens

He, Y. X., Huang, L., Xue, Y., Fei, X., Teng, Y. B., Rubin-Pitel, S. B., Zhao, H. & Zhou, C. Z., Feb 12 2010, In : Journal of Biological Chemistry. 285, 7, p. 4603-4611 9 p.

Research output: Contribution to journalArticle

Discovery and characterization of novel d-xylose-specific transporters from Neurospora crassa and Pichia stipitis

Du, J., Li, S. & Zhao, H., Nov 1 2010, In : Molecular BioSystems. 6, 11, p. 2150-2156 7 p.

Research output: Contribution to journalArticle

2015

Chromatin architecture reorganization during stem cell differentiation

Dixon, J. R., Jung, I., Selvaraj, S., Shen, Y., Antosiewicz-Bourget, J. E., Lee, A. Y., Ye, Z., Kim, A., Rajagopal, N., Xie, W., Diao, Y., Liang, J., Zhao, H., Lobanenkov, V. V., Ecker, J. R., Thomson, J. A. & Ren, B., Feb 19 2015, In : Nature. 518, 7539, p. 331-336 6 p.

Research output: Contribution to journalArticle

Regulatory RNA-assisted genome engineering in microorganisms

Si, T., HamediRad, M. & Zhao, H., Dec 1 2015, In : Current Opinion in Biotechnology. 36, p. 85-90 6 p.

Research output: Contribution to journalReview article

2012

Biocatalyst development by directed evolution

Wang, M., Si, T. & Zhao, H., Jul 2012, In : Bioresource Technology. 115, p. 117-125 9 p.

Research output: Contribution to journalArticle

2017

A plug-and-play pathway refactoring workflow for natural product research in Escherichia coli and Saccharomyces cerevisiae

Ren, H., Hu, P. & Zhao, H., Aug 2017, In : Biotechnology and bioengineering. 114, 8, p. 1847-1854 8 p.

Research output: Contribution to journalArticle

2011

A new fluorescence complementation biosensor for detection of estrogenic compounds

Mclachlan, M. J., Katzenellenbogen, J. A. & Zhao, H., Dec 2011, In : Biotechnology and bioengineering. 108, 12, p. 2794-2803 10 p.

Research output: Contribution to journalArticle

2016

ACS Catalysis and the Scope of Papers Sought in Three Catalysis Subdisciplines: Biocatalysis and Enzymology, Molecular Catalysis for Organic Synthesis, and Heterogeneous Photocatalysis

Chang, S., Fornasiero, P., Gunnoe, T. B., Jones, C. W., Linic, S., Ooi, T., Williams, R. M. & Zhao, H., Jul 1 2016, In : ACS Catalysis. 6, 7, p. 4782-4785 4 p.

Research output: Contribution to journalReview article

2015

High throughput screening and selection methods for directed enzyme evolution

Xiao, H., Bao, Z. & Zhao, H., Apr 29 2015, In : Industrial and Engineering Chemistry Research. 54, 16, p. 4011-4020 10 p.

Research output: Contribution to journalArticle

2011

Engineering microbial factories for synthesis of value-added products

Du, J., Shao, Z. & Zhao, H., Aug 2011, In : Journal of Industrial Microbiology and Biotechnology. 38, 8, p. 873-890 18 p.

Research output: Contribution to journalReview article

2017

Breaking the silence: new strategies for discovering novel natural products

Ren, H., Wang, B. & Zhao, H., Dec 1 2017, In : Current Opinion in Biotechnology. 48, p. 21-27 7 p.

Research output: Contribution to journalReview article

2016

Rapid and efficient galactose fermentation by engineered Saccharomyces cerevisiae

Quarterman, J., Skerker, J. M., Feng, X., Liu, I. Y., Zhao, H., Arkin, A. P. & Jin, Y. S., Jul 10 2016, In : Journal of Biotechnology. 229, p. 13-21 9 p.

Research output: Contribution to journalArticle

2014

Directed evolution of a cellodextrin transporter for improved biofuel production under anaerobic conditions in Saccharomyces cerevisiae

Lian, J., Li, Y., HamediRad, M. & Zhao, H., Aug 2014, In : Biotechnology and bioengineering. 111, 8, p. 1521-1531 11 p.

Research output: Contribution to journalArticle

2019

Development of a CRISPR/Cas9-based tool for gene deletion in Issatchenkia orientalis

Tran, V. G., Cao, M., Fatma, Z., Song, X. & Zhao, H., May 1 2019, In : mSphere. 4, 3, e00345-19.

Research output: Contribution to journalArticle

Open Access
2016

RNAi-assisted genome evolution (RAGE) in Saccharomyces cerevisiae

Si, T. & Zhao, H., Jan 1 2016, In : Methods in Molecular Biology. 1470, p. 183-198 16 p.

Research output: Contribution to journalArticle

2019

Towards a fully automated algorithm driven platform for biosystems design

HamediRad, M., Chao, R., Weisberg, S., Lian, J., Sinha, S. & Zhao, H., Nov 13 2019, In : Nature communications. 10, 1, 5150.

Research output: Contribution to journalArticle

Open Access
2018
2019

Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes

Yeo, W. L., Heng, E., Tan, L. L., Lim, Y. W., Lim, Y. H., Hoon, S., Zhao, H., Zhang, M. M. & Wong, F. T., 2019, In : Biotechnology and bioengineering. 116, 9, p. 2330-2338 9 p.

Research output: Contribution to journalArticle

2015

High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System

Cobb, R. E., Wang, Y. & Zhao, H., Jun 19 2015, In : ACS synthetic biology. 4, 6, p. 723-728 6 p.

Research output: Contribution to journalArticle

2016

High-throughput screening or selection methods for evolutionary enzyme engineering

Shi, S., Zhang, H., Ang, E. L. & Zhao, H., May 17 2016, Understanding Enzymes: Function, Design, Engineering and Analysis. Pan Stanford Publishing Pte. Ltd., p. 707-744 38 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Pathway design, engineering, and optimization

Garcia-Ruiz, E., HamediRad, M. & Zhao, H., Jan 1 2018, Advances in Biochemical Engineering/Biotechnology. Springer Science and Business Media Deutschland GmbH, (Advances in Biochemical Engineering/Biotechnology; vol. 162).

Research output: Chapter in Book/Report/Conference proceedingChapter

Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System

Lian, J., HamediRad, M. & Zhao, H., Sep 2018, In : Biotechnology Journal. 13, 9, 1700601.

Research output: Contribution to journalReview article

2011

Cloning and characterization of a type III polyketide synthase from Aspergillus niger

Li, J., Luo, Y., Lee, J. K. & Zhao, H., Oct 15 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 20, p. 6085-6089 5 p.

Research output: Contribution to journalArticle

Synthetic biology: Putting synthesis into biology

Liang, J., Luo, Y. & Zhao, H., Jan 1 2011, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 3, 1, p. 7-20 14 p.

Research output: Contribution to journalReview article

2019

A continuing career in biocatalysis: Frances H. Arnold

Fasan, R., Jennifer Kan, S. B. & Zhao, H., Nov 1 2019, In : ACS Catalysis. 9, 11, p. 9775-9788 14 p.

Research output: Contribution to journalArticle

2012

Role of conserved glycine in zinc-dependent medium chain dehydrogenase/reductase superfamily

Tiwari, M. K., Singh, R. K., Singh, R., Jeya, M., Zhao, H. & Lee, J. K., Jun 1 2012, In : Journal of Biological Chemistry. 287, 23, p. 19429-19439 11 p.

Research output: Contribution to journalArticle

2019

Biochemical and structural investigation of sulfoacetaldehyde reductase from Klebsiella oxytoca

Zhou, Y., Wei, Y., Lin, L., Xu, T., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jan 1 2019, In : Biochemical Journal. 476, 4, p. 733-746 14 p.

Research output: Contribution to journalArticle

A pathway for isethionate dissimilation in Bacillus krulwichiae

Tong, Y., Wei, Y., Hu, Y., Ang, E. L., Zhao, H. & Zhang, Y., 2019, In : Applied and environmental microbiology. 85, 15, e00793-19.

Research output: Contribution to journalArticle

2016

Engineered minicellulosomes for consolidated bioprocessing

Liang, Y., Ang, E. L. & Zhao, H., Jul 11 2016, Handbook of Carbohydrate-Modifying Biocatalysts. Pan Stanford Publishing Pte. Ltd., Vol. 2. p. 965-992 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Engineering chimeric RNA-binding proteins: Modular design, novel function

Abil, Z., Denard, C. A., Hoogenraad, C. & Zhao, H., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, 1 p. (Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Design and construction of acetyl-CoA overproducing Saccharomyces cerevisiae strains

Lian, J., Si, T., Nair, N. U. & Zhao, H., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, p. 750-760 11 p. (Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2011

Combinatorial optimization of a highly efficient xylose utilization pathway in saccharomyces cerevisiae

Du, J., Kim, B. & Zhao, H., Dec 1 2011, 11AIChE - 2011 AIChE Annual Meeting, Conference Proceedings. (11AIChE - 2011 AIChE Annual Meeting, Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2015

Recent advances in DNA assembly technologies

Chao, R., Yuan, Y. & Zhao, H., 2015, In : FEMS yeast research. 15, 1, 12171.

Research output: Contribution to journalShort survey

2014

Characterization and engineering of the adenylation domain of a NRPS-like protein: A potential biocatalyst for aldehyde generation

Wang, M. & Zhao, H., Apr 4 2014, In : ACS Catalysis. 4, 4, p. 1219-1225 7 p.

Research output: Contribution to journalArticle

2016

Accelerated genome engineering through multiplexing

Bao, Z., Cobb, R. E. & Zhao, H., Jan 1 2016, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 8, 1, p. 5-21 17 p.

Research output: Contribution to journalReview article

2015

Improving and repurposing biocatalysts via directed evolution

Denard, C. A., Ren, H. & Zhao, H., Apr 1 2015, In : Current Opinion in Chemical Biology. 25, p. 55-64 10 p.

Research output: Contribution to journalReview article

2018

Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis

Litman, Z. C., Wang, Y., Zhao, H. & Hartwig, J. F., Aug 16 2018, In : Nature. 560, 7718, p. 355-359 5 p.

Research output: Contribution to journalArticle

2016

Editorial: Synthetic biology and bioinformatics

Medema, M. H. & Zhao, H., Aug 2016, In : Natural Product Reports. 33, 8, p. 913-914 2 p.

Research output: Contribution to journalEditorial

2012

DNA assembler: A synthetic biology tool for characterizing and engineering natural product gene clusters

Shao, Z. & Zhao, H., 2012, Natural Product Biosynthesis by Microorganisms and Plants, Part C. Academic Press Inc., p. 203-224 22 p. (Methods in Enzymology; vol. 517).

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Protein design for pathway engineering

Eriksen, D. T., Lian, J. & Zhao, H., Feb 2014, In : Journal of Structural Biology. 185, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

2012

Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration

Zou, Y., Zhang, H., Brunzelle, J. S., Johannes, T. W., Woodyer, R., Hung, J. E., Nair, N., Van Der Donk, W. A., Zhao, H. & Nair, S. K., May 29 2012, In : Biochemistry. 51, 21, p. 4263-4270 8 p.

Research output: Contribution to journalArticle