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2019

DNAzyme-based biosensor as a rapid and accurate verification tool to complement simultaneous enzyme-based media for: E. Coli detection

Zaouri, N., Cui, Z., Peinetti, A. S., Lu, Y. & Hong, P. Y., Dec 2019, In : Environmental Science: Water Research and Technology. 5, 12, p. 2260-2268 9 p.

Research output: Contribution to journalArticle

Open Access
Biosensors
Escherichia coli
Enzymes
enzyme
fluorescence
2010

Label-free fluorescent functional DNA sensors using unmodified DNA: A vacant site approach

Xiang, Y., Wang, Z., Xing, H., Wong, N. Y. & Lu, Y., May 15 2010, In : Analytical chemistry. 82, 10, p. 4122-4129 8 p.

Research output: Contribution to journalArticle

Labels
DNA
Sensors
Catalytic DNA
Adenosine

Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates

Lee, J. H., Yigit, M. V., Mazumdar, D. & Lu, Y., Apr 1 2010, In : Advanced Drug Delivery Reviews. 62, 6, p. 592-605 14 p.

Research output: Contribution to journalReview article

Molecular Pathology
Nanostructures
Nanoparticles
Quantum Dots
Carbon Nanotubes
2012

Direct detection of adenosine in undiluted serum using a luminescent aptamer sensor attached to a terbium complex

Li, L. L., Ge, P., Selvin, P. R. & Lu, Y., Sep 18 2012, In : Analytical chemistry. 84, 18, p. 7852-7856 5 p.

Research output: Contribution to journalArticle

Terbium
Biosensors
Adenosine
Sensors
Nucleic Acids
2016

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

Zhang, J. J., Cheng, F. F., Li, J. J., Zhu, J. J. & Lu, Y., Jun 1 2016, In : Nano Today. 11, 3, p. 309-329 21 p.

Research output: Contribution to journalReview article

Nanoprobes
Nanostructures
Nanostructured materials
Metal ions
Quantum Dots
2012

Spectroscopic and DFT studies of second-sphere variants of the type 1 copper site in azurin: Covalent and nonlocal electrostatic contributions to reduction potentials

Hadt, R. G., Sun, N., Marshall, N. M., Hodgson, K. O., Hedman, B., Lu, Y. & Solomon, E. I., Oct 10 2012, In : Journal of the American Chemical Society. 134, 40, p. 16701-16716 16 p.

Research output: Contribution to journalArticle

Azurin
Static Electricity
Discrete Fourier transforms
Copper
Electrostatics
2014

Spectroscopic and computational study of a nonheme iron nitrosyl center in a biosynthetic model of nitric oxide reductase

Chakraborty, S., Reed, J., Ross, M., Nilges, M. J., Petrik, I. D., Ghosh, S., Hammes-Schiffer, S., Sage, J. T., Zhang, Y., Schulz, C. E. & Lu, Y., Feb 24 2014, In : Angewandte Chemie - International Edition. 53, 9, p. 2417-2421 5 p.

Research output: Contribution to journalArticle

Nitric oxide
Iron
Heme
Myoglobin
Electronic states
2015

Using DNA aptamer probe for immunostaining of cancer frozen tissues

Pu, Y., Liu, Z., Lu, Y., Yuan, P., Liu, J., Yu, B., Wang, G., Yang, C. J., Liu, H. & Tan, W., Feb 3 2015, In : Analytical chemistry. 87, 3, p. 1919-1924 6 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Cell Adhesion Molecules
Tissue
Paraffin
Tumors
2019

S-Click Reaction for Isotropic Orientation of Oxidases on Electrodes to Promote Electron Transfer at Low Potentials

Xia, L., Han, M. J., Zhou, L., Huang, A., Yang, Z., Wang, T., Li, F., Yu, L., Tian, C., Zang, Z., Yang, Q. Z., Liu, C., Hong, W., Lu, Y., Alfonta, L. & Wang, J., Nov 11 2019, In : Angewandte Chemie - International Edition. 58, 46, p. 16480-16484 5 p.

Research output: Contribution to journalArticle

Oxidoreductases
Enzymes
Electrochemical sensors
Electrodes
Electrons
2014

DNazyme-functionalized gold nanoparticles for biosensing

Xiang, Y., Wu, P., Tan, L. H. & Lu, Y., Jan 1 2014, In : Advances in Biochemical Engineering/Biotechnology. 140, p. 93-120 28 p.

Research output: Contribution to journalArticle

Catalytic DNA
Gold
Nanoparticles
Metal ions
DNA
2015

Compound Q is finally deciphered

Bhagi-Damodaran, A. & Lu, Y., Sep 1 2015, In : Inorganic Chemistry Frontiers. 2, 9, p. 824-826 3 p.

Research output: Contribution to journalArticle

methane monooxygenase
Trichosanthin
Methane
Methanol
2013

Enhanced and tunable fluorescent quantum dots within a single crystal of protein

Wei, H., House, S., Wu, J., Zhang, J., Wang, Z., He, Y., Gao, E. J., Gao, Y., Robinson, H., Li, W., Zuo, J-M., Robertson, I. M. & Lu, Y., Sep 1 2013, In : Nano Research. 6, 9, p. 627-634 8 p.

Research output: Contribution to journalArticle

Muramidase
Semiconductor quantum dots
Enzymes
Single crystals
Proteins
2012

A designed functional metalloenzyme that reduces O 2 to H 2O with over one thousand turnovers

Miner, K. D., Mukherjee, A., Gao, Y. G., Null, E. L., Petrik, I. D., Zhao, X., Yeung, N., Robinson, H. & Lu, Y., Jun 4 2012, In : Angewandte Chemie - International Edition. 51, 23, p. 5589-5592 4 p.

Research output: Contribution to journalArticle

Enzymes
Myoglobin
Reactive Oxygen Species
Oxidoreductases
Oxygen
2015

Nanomaterial-based biosensors using dual transducing elements for solution phase detection

Li, N., Su, X. & Lu, Y., May 7 2015, In : Analyst. 140, 9, p. 2916-2943 28 p.

Research output: Contribution to journalReview article

Nanostructures
Biosensing Techniques
transducer
Nanostructured materials
Biosensors
2011

Spectroscopic characterization of mononitrosyl complexes in heme-nonheme diiron centers within the myoglobin scaffold (FeBMbs): Relevance to denitrifying No reductase

Hayashi, T., Miner, K. D., Yeung, N., Lin, Y. W., Lu, Y. & Moënne-Loccoz, P., Jul 5 2011, In : Biochemistry. 50, 26, p. 5939-5947 9 p.

Research output: Contribution to journalArticle

Myoglobin
Heme
Scaffolds
Oxidoreductases
Paramagnetic resonance
2013

PH-dependent evolution of five-star gold nanostructures: An experimental and computational study

Wang, Z., Bharathi, M. S., Hariharaputran, R., Xing, H., Tang, L., Li, J., Zhang, Y. W. & Lu, Y., Mar 26 2013, In : ACS Nano. 7, 3, p. 2258-2265 8 p.

Research output: Contribution to journalArticle

Gold
Stars
Nanostructures
gold
stars

Rational Design of Protein Cages for Alternative Enzymatic Functions

Marshall, N. M., Miner, K. D., Wilson, T. D. & Lu, Y., Apr 2 2013, Coordination Chemistry in Protein Cages: Principles, Design, and Applications. John Wiley and Sons, p. 111-147 37 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteins
Catalysis
Scaffolds
Electrons
Inorganic Chemistry
2010

Branched silica nanostructures oriented by dynamic G-quadruplex transformation

Zhang, J., Zheng, L., Wang, X., Xiao, Y., Lu, Y. & Li, W., Dec 1 2010, In : Materials Research Bulletin. 45, 12, p. 1954-1959 6 p.

Research output: Contribution to journalArticle

Silicon Dioxide
Nanostructures
Silica
silicon dioxide
oligonucleotides
2013

Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo

Xing, H., Tang, L., Yang, X., Hwang, K., Wang, W., Yin, Q., Wong, N. Y., Dobrucki, L. W., Yasui, N., Katzenellenbogen, J. A., Helferich, W. G., Cheng, J. & Lu, Y., Oct 21 2013, In : Journal of Materials Chemistry B. 1, 39, p. 5288-5297 10 p.

Research output: Contribution to journalArticle

Liposomes
Cells
Nucleotide Aptamers
Breast Neoplasms
Nude Mice
2015

In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing

Torabi, S. F., Wu, P., McGhee, C. E., Chen, L., Hwang, K., Zheng, N., Cheng, J. & Lu, Y., May 12 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 19, p. 5903-5908 6 p.

Research output: Contribution to journalArticle

Catalytic DNA
Sodium
Metals
Ions
Ribonucleotides
2018

DNA-encoded morphological evolution of bimetallic Pd@Au core-shell nanoparticles from a high-indexed core

Satyavolu, N. S. R., Pishevaresfahani, N., Tan, L. H. & Lu, Y., Sep 1 2018, In : Nano Research. 11, 9, p. 4549-4561 13 p.

Research output: Contribution to journalArticle

Seed
DNA
Nanoparticles
Palladium
Interfacial energy
2019

Silver-Assisted Synthesis of High-Indexed Palladium Tetrahexahedral Nanoparticles and Their Morphological Variants

Satyavolu, N. S. R., Peinetti, A. S., Wang, Y., Ali, A. S., Lin, J. W. & Lu, Y., Apr 23 2019, In : Chemistry of Materials. 31, 8, p. 2923-2929 7 p.

Research output: Contribution to journalArticle

Palladium
Silver
Nanoparticles
Interfacial energy
Seed
2011
Catalytic DNA
Metal ions
Ionic strength
Fluorescence Resonance Energy Transfer
Catalysis
2013

A dual-emission fluorescent nanocomplex of gold-cluster-decorated silica particles for live cell imaging of highly reactive oxygen species

Chen, T., Hu, Y., Cen, Y., Chu, X. & Lu, Y., Aug 7 2013, In : Journal of the American Chemical Society. 135, 31, p. 11595-11602 8 p.

Research output: Contribution to journalArticle

Silicon Dioxide
Gold
Reactive Oxygen Species
gold
silica
2010

DNA-mediated control of metal nanoparticle shape: One-pot synthesis and cellular uptake of highly stable and functional gold nanoflowers

Wang, Z., Zhang, J., Ekman, J. M., Kenis, P. J. A. & Lu, Y., May 12 2010, In : Nano letters. 10, 5, p. 1886-1891 6 p.

Research output: Contribution to journalArticle

Nanoflowers
Metal nanoparticles
Gold
DNA
deoxyribonucleic acid
2016

Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics

Hosseinzadeh, P. & Lu, Y., May 1 2016, In : Biochimica et Biophysica Acta - Bioenergetics. 1857, 5, p. 557-581 25 p.

Research output: Contribution to journalArticle

Metalloproteins
Energy Metabolism
Oxidation-Reduction
Tuning
Electrons
2014

Functional Nucleic Acid-Directed Assembly of Nanomaterials and Their Applications as Colorimetric and Fluorescent Sensors for Trace Contaminants in Water

Mazumdar, D., Liu, J. & Lu, Y., May 6 2014, Nanotechnology Applications for Clean Water: Solutions for Improving Water Quality: Second Edition. Elsevier Inc., p. 73-92 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nucleic acids
Nanostructured materials
Impurities
Molecules
Sensors
2016

A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site

Hosseinzadeh, P., Tian, S., Marshall, N. M., Hemp, J., Mullen, T., Nilges, M. J., Gao, Y. G., Robinson, H., Stahl, D. A., Gennis, R. B. & Lu, Y., May 25 2016, In : Journal of the American Chemical Society. 138, 20, p. 6324-6327 4 p.

Research output: Contribution to journalArticle

Binding sites
Copper
Binding Sites
electron spin resonance
copper
2012

A new ratiometric and colorimetric chemosensor for cyanide anion based on Coumarin-hemicyanine hybrid

Yang, Z., Liu, Z., Chen, Y., Wang, X., He, W. & Lu, Y., Jul 14 2012, In : Organic and Biomolecular Chemistry. 10, 26, p. 5073-5076 4 p.

Research output: Contribution to journalArticle

Cyanides
cyanides
Anions
anions
conjugation
2011

Site-specific attachment of proteins onto a 3D DNA tetrahedron through backbone-modified phosphorothioate DNA

Wong, N. Y., Zhang, C., Tan, L. H. & Lu, Y., May 23 2011, In : Small. 7, 10, p. 1427-1430 4 p.

Research output: Contribution to journalArticle

DNA
Proteins
Nanostructures

The important role of covalent anchor positions in tuning catalytic properties of a rationally designed Mnsalen-containing metalloenzyme

Garner, D. K., Liang, L., Barrios, D. A., Zhang, J. L. & Lu, Y., Sep 2 2011, In : ACS Catalysis. 1, 9, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

Anchors
Tuning
Myoglobin
Catalyst selectivity
Enantioselectivity
2017

Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand

Xing, H., Bai, Y., Bai, Y., Tan, L. H., Tao, J., Pedretti, B., Vincil, G. A., Lu, Y. & Zimmerman, S. C., Mar 15 2017, In : Journal of the American Chemical Society. 139, 10, p. 3623-3626 4 p.

Research output: Contribution to journalArticle

Nanoparticles
DNA
Gold
Block copolymers
fluorescence
2010

Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin

Lin, Y. W., Yeung, N., Gao, Y. G., Miner, K. D., Tian, S., Robinson, H. & Lu, Y., May 11 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 19, p. 8581-8586 6 p.

Research output: Contribution to journalArticle

Glutamates
Myoglobin
Metals
Ions
Heme
2016

A density functional theory protocol for the calculation of redox potentials of copper complexes

Yan, L., Lu, Y. & Li, X., Jan 1 2016, In : Physical Chemistry Chemical Physics. 18, 7, p. 5529-5536 8 p.

Research output: Contribution to journalArticle

Gibbs free energy
Density functional theory
Copper
density functional theory
Redox reactions
2014

DNA as sensors and imaging agents for metal ions

Xiang, Y. & Lu, Y., Feb 17 2014, In : Inorganic Chemistry. 53, 4, p. 1925-1942 18 p.

Research output: Contribution to journalReview article

Metal ions
metal ions
deoxyribonucleic acid
Imaging techniques
DNA
2019

Y-Shaped Backbone-Rigidified Triangular DNA Scaffold-Directed Stepwise Movement of a DNAzyme Walker for Sensitive MicroRNA Imaging within Living Cells

Xue, C., Zhang, S., Li, C., Yu, X., Ouyang, C., Lu, Y. & Wu, Z. S., Dec 17 2019, In : Analytical chemistry. 91, 24, p. 15678-15685 8 p.

Research output: Contribution to journalArticle

Catalytic DNA
MicroRNAs
Scaffolds
Cells
Imaging techniques

Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications

Zhang, J. J., Lan, T. & Lu, Y., Mar 21 2019, In : Advanced Healthcare Materials. 8, 6, 1801158.

Research output: Contribution to journalReview article

Nanostructures
Nucleic acids
Nanostructured materials
Nucleic Acids
Point-of-Care Systems
2011

Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets

Xiang, Y. & Lu, Y., Sep 1 2011, In : Nature Chemistry. 3, 9, p. 697-703 7 p.

Research output: Contribution to journalArticle

beta-Fructofuranosidase
Glucose
DNA
Sensors
Catalytic DNA
2015

Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

Yu, Y., Lv, X., Li, J., Zhou, Q., Cui, C., Hosseinzadeh, P., Mukherjee, A., Nilges, M. J., Wang, J. & Lu, Y., Apr 15 2015, In : Journal of the American Chemical Society. 137, 14, p. 4594-4597 4 p.

Research output: Contribution to journalArticle

Tyrosine
Oxidoreductases
Tuning
Phenols
phenol
2016

Size-dependent modulation of graphene oxide-aptamer interactions for an amplified fluorescence-based detection of aflatoxin B1 with a tunable dynamic range

Zhang, J., Li, Z., Zhao, S. & Lu, Y., Jul 7 2016, In : Analyst. 141, 13, p. 4029-4034 6 p.

Research output: Contribution to journalArticle

Aflatoxins
Aflatoxin B1
Graphite
Oxides
Graphene
2015

Mechanistic Insight into DNA-Guided Control of Nanoparticle Morphologies

Tan, L. H., Yue, Y., Satyavolu, N. S. R., Ali, A. S., Wang, Z., Wu, Y. & Lu, Y., Oct 22 2015, In : Journal of the American Chemical Society. 137, 45, p. 14456-14464 9 p.

Research output: Contribution to journalArticle

Nanoparticles
DNA
Nanostructures
Nanostructured materials
Seed
2011

Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme

Wei, H., Wang, Z., Zhang, J., House, S., Gao, Y. G., Yang, L., Robinson, H., Tan, L. H., Xing, H., Hou, C., Robertson, I. M., Zuo, J. M. & Lu, Y., Feb 2011, In : Nature Nanotechnology. 6, 2, p. 93-97 5 p.

Research output: Contribution to journalArticle

lysozyme
Muramidase
Gold
Enzymes
Single crystals
2010

Lysozyme-stabilized gold fluorescent cluster: Synthesis and application as Hg2+ sensor

Wei, H., Wang, Z., Yang, L., Tian, S., Hou, C. & Lu, Y., Jun 1 2010, In : Analyst. 135, 6, p. 1406-1410 5 p.

Research output: Contribution to journalArticle

Muramidase
Gold
Enzymes
gold
sensor
2011

Kinetics of copper incorporation into a biosynthetic purple Cu A azurin: Characterization of red, blue, and a new intermediate species

Wilson, T. D., Savelieff, M. G., Nilges, M. J., Marshall, N. M. & Lu, Y., Dec 28 2011, In : Journal of the American Chemical Society. 133, 51, p. 20778-20792 15 p.

Research output: Contribution to journalArticle

Azurin
Copper
copper
kinetics
Kinetics

A smart magnetic resonance imaging contrast agent responsive to adenosine based on a DNA aptamer-conjugated gadolinium complex

Xu, W. & Lu, Y., May 7 2011, In : Chemical Communications. 47, 17, p. 4998-5000 3 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Gadolinium
Magnetic resonance
Adenosine
Magnetic resonance imaging
2013

A vitamin-responsive mesoporous nanocarrier with DNA aptamer-mediated cell targeting

Li, L. L., Xie, M., Wang, J., Li, X., Wang, C., Yuan, Q., Pang, D. W., Lu, Y. & Tan, W., Jul 4 2013, In : Chemical Communications. 49, 52, p. 5823-5825 3 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Vitamins
DNA
Cells
Proteins
2016

Reversible S-nitrosylation in an engineered azurin

Tian, S., Liu, J., Cowley, R. E., Hosseinzadeh, P., Marshall, N. M., Yu, Y., Robinson, H., Nilges, M. J., Blackburn, N. J., Solomon, E. I. & Lu, Y., Jul 1 2016, In : Nature Chemistry. 8, 7, p. 670-677 8 p.

Research output: Contribution to journalArticle

Azurin
Copper
S-Nitrosothiols
Metalloproteins
Proteins
2013

Functional DNA-integrated nanomaterials for biosensing

Li, L. & Lu, Y., Aug 1 2013, DNA Nanotechnology: From Structure to Function. Springer-Verlag Berlin Heidelberg, Vol. 9783642360770. p. 277-305 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nanostructures
Nanostructured materials
DNA
Nanoparticles
Molecules
2012

Redox tuning of two biological copper centers through non-covalent interactions: Same trend but different magnitude

New, S. Y., Marshall, N. M., Hor, T. S. A., Xue, F. & Lu, Y., May 4 2012, In : Chemical Communications. 48, 35, p. 4217-4219 3 p.

Research output: Contribution to journalArticle

Azurin
Copper
Tuning
Proteins
Scaffolds (biology)

Discovery of the DNA "genetic code" for abiological gold nanoparticle morphologies

Wang, Z., Tang, L., Tan, L. H., Li, J. & Lu, Y., Sep 3 2012, In : Angewandte Chemie - International Edition. 51, 36, p. 9078-9082 5 p.

Research output: Contribution to journalArticle

Gold
DNA
Oligonucleotides
Nanoparticles
Nucleotides