Find Research Outputs

Search in all content

Filters for Research & Scholarship

Search concepts
Selected Filters

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010

Author

  • Huimin Zhao
2013

Pathway engineering as an enabling synthetic biology tool

Eriksen, D. T., Li, S. & Zhao, H., Aug 27 2013, Synthetic Biology. Elsevier Inc., p. 43-61 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Twin-primer non-enzymatic DNA assembly: An efficient and accurate multi-part DNA assembly method

Liang, J., Liu, Z., Low, X. Z., Ang, E. L. & Zhao, H., Jun 1 2017, In : Nucleic acids research. 45, 11, p. e94

Research output: Contribution to journalArticle

2015

Illinois Biological Foundry for Advanced Biomanufacturing (iBioFAB)

Zhao, H., Jan 1 2015, Synthetic Biology: Engineering, Evolution, and Design Conference 2015, SEED 2015. AIChE, p. 784-785 2 p. (Synthetic Biology: Engineering, Evolution, and Design Conference 2015, SEED 2015; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2019

A gene cluster for taurine sulfur assimilation in an anaerobic human gut bacterium

Xing, M., Wei, Y., Hua, G., Li, M., Nanjaraj Urs, A. N., Wang, F., Hu, Y., Zhai, W., Liu, Y., Ang, E. L., Zhao, H. & Zhang, Y., Aug 15 2019, In : Biochemical Journal. 476, 15, p. 2271-2279 9 p.

Research output: Contribution to journalArticle

2012

Direct conversion of xylan to ethanol by recombinant Saccharomyces cerevisiae strains displaying an engineered minihemicellulosome

Sun, J., Wen, F., Si, T., Xu, J. H. & Zhao, H., Jun 1 2012, In : Applied and environmental microbiology. 78, 11, p. 3837-3845 9 p.

Research output: Contribution to journalArticle

2017

Combining Rh-Catalyzed Diazocoupling and Enzymatic Reduction to Efficiently Synthesize Enantioenriched 2-Substituted Succinate Derivatives

Wang, Y., Bartlett, M. J., Denard, C. A., Hartwig, J. F. & Zhao, H., Apr 7 2017, In : ACS Catalysis. 7, 4, p. 2548-2552 5 p.

Research output: Contribution to journalArticle

2014

Tandem catalytic conversion of glucose to 5-hydroxymethylfurfural with an immobilized enzyme and a solid acid

Huang, H., Denard, C. A., Alamillo, R., Crisci, A. J., Miao, Y., Dumesic, J. A., Scott, S. L. & Zhao, H., Jul 3 2014, In : ACS Catalysis. 4, 7, p. 2165-2168 4 p.

Research output: Contribution to journalArticle

2018

Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface

Limsakul, P., Peng, Q., Wu, Y., Allen, M. E., Liang, J., Remacle, A. G., Lopez, T., Ge, X., Kay, B. K., Zhao, H., Strongin, A. Y., Yang, X. L., Lu, S. & Wang, Y., Apr 19 2018, In : Cell chemical biology. 25, 4, p. 370-379.e4

Research output: Contribution to journalArticle

2019

An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine

Yin, J., Wei, Y., Liu, D., Hu, Y., Lu, Q., Lui Ang, E., Zhao, H. & Zhang, Y., Oct 25 2019, In : Journal of Biological Chemistry. 294, 43, p. 15662-15671 10 p.

Research output: Contribution to journalArticle

2013

Customized optimization of metabolic pathways by combinatorial transcriptional engineering.

Yuan, Y., Du, J. & Zhao, H., Aug 2 2013, In : Methods in molecular biology (Clifton, N.J.). 985, p. 177-209 33 p.

Research output: Contribution to journalArticle

2017

Targeting Specificity of the CRISPR/Cas9 System

Tasan, I. & Zhao, H., Sep 15 2017, In : ACS synthetic biology. 6, 9, p. 1609-1613 5 p.

Research output: Contribution to journalReview article

2013

Directed evolution as a powerful synthetic biology tool

Cobb, R. E., Sun, N. & Zhao, H., Mar 15 2013, In : Methods. 60, 1, p. 81-90 10 p.

Research output: Contribution to journalReview article

2014

Recent advances in natural product discovery

Luo, Y., Cobb, R. E. & Zhao, H., Dec 1 2014, In : Current Opinion in Biotechnology. 30, p. 230-237 8 p.

Research output: Contribution to journalReview article

2018

Synthetic biology advances and applications in the biotechnology industry: a perspective

Katz, L., Chen, Y. Y., Gonzalez, R., Peterson, T. C., Zhao, H. & Baltz, R. H., Jul 1 2018, In : Journal of Industrial Microbiology and Biotechnology. 45, 7, p. 449-461 13 p.

Research output: Contribution to journalArticle

2010
2017

Inducible Control of mRNA Transport Using Reprogrammable RNA-Binding Proteins

Abil, Z., Gumy, L. F., Zhao, H. & Hoogenraad, C. C., Jun 16 2017, In : ACS synthetic biology. 6, 6, p. 950-956 7 p.

Research output: Contribution to journalArticle

2014

SunnyTALEN: A second-generation TALEN system for human genome editing

Sun, N., Bao, Z., Xiong, X. & Zhao, H., Apr 2014, In : Biotechnology and bioengineering. 111, 4, p. 683-691 9 p.

Research output: Contribution to journalArticle

2018

Metabolic Engineering of Saccharomyces cerevisiae Using a Trifunctional CRISPR/Cas System for Simultaneous Gene Activation, Interference, and Deletion

Schultz, C., Lian, J. & Zhao, H., Jan 1 2018, Methods in Enzymology. Scrutton, N. (ed.). Academic Press Inc., p. 265-276 12 p. (Methods in Enzymology; vol. 608).

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNA

Abil, Z., Denard, C. A. & Zhao, H., Mar 1 2014, In : Journal of Biological Engineering. 8, 1, 7.

Research output: Contribution to journalArticle

2015

In Situ Assembly of Antifouling/Bacterial Silver Nanoparticle-Hydrogel Composites with Controlled Particle Release and Matrix Softening

Baek, K., Liang, J., Lim, W. T., Zhao, H., Kim, D. H. & Kong, H., Jul 22 2015, In : ACS Applied Materials and Interfaces. 7, 28, p. 15359-15367 9 p.

Research output: Contribution to journalArticle

2013

Directed evolution of a cellobiose utilization pathway in Saccharomyces cerevisiae by simultaneously engineering multiple proteins

Eriksen, D. T., Hsieh, P. C. H., Lynn, P. & Zhao, H., Jun 26 2013, In : Microbial cell factories. 12, 1, 61.

Research output: Contribution to journalArticle

2016

Metabolic engineering of Saccharomyces cerevisiae to produce 1-hexadecanol from xylose

Guo, W., Sheng, J., Zhao, H. & Feng, X., Feb 1 2016, In : Microbial cell factories. 15, 1, 24.

Research output: Contribution to journalArticle

2010

Selective reduction of xylose to xylitol from a mixture of hemicellulosic sugars

Nair, N. U. & Zhao, H., Sep 1 2010, In : Metabolic Engineering. 12, 5, p. 462-468 7 p.

Research output: Contribution to journalArticle

2017
2013

Synthetic Biology

Zhao, H., Jan 1 2013, Elsevier Inc.

Research output: Book/Report/Conference proceedingBook

2014

Homology-integrated CRISPR-cas (HI-CRISPR) system for one-step multigene disruption in saccharomyces cerevisiae

Bao, Z., Xiao, H., Liang, J., Zhang, L., Xiong, X., Sun, N., Si, T. & Zhao, H., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, p. 27-36 10 p. (Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2018

Recent developments in the application of P450 based biocatalysts

Wei, Y., Ang, E. L. & Zhao, H., Apr 2018, In : Current Opinion in Chemical Biology. 43, p. 1-7 7 p.

Research output: Contribution to journalReview article

2014

Comparative biochemical characterization of three exolytic oligoalginate lyases from Vibrio splendidus reveals complementary substrate scope, temperature, and pH adaptations

Jagtap, S. S., Hehemann, J. H., Polz, M. F., Lee, J. K. & Zhao, H., 2014, In : Applied and environmental microbiology. 80, 14, p. 4207-4214 8 p.

Research output: Contribution to journalArticle

2018

Rapid Discovery of Glycocins through Pathway Refactoring in Escherichia coli

Ren, H., Biswas, S., Ho, S., Van Der Donk, W. A. & Zhao, H., Oct 19 2018, In : ACS chemical biology. 13, 10, p. 2966-2972 7 p.

Research output: Contribution to journalArticle

2013

Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing.

Sun, N. & Zhao, H., Jul 2013, In : Biotechnology and bioengineering. 110, 7, p. 1811-1821 11 p.

Research output: Contribution to journalReview article

2014

Manipulating natural product biosynthetic pathways via DNA assembler

Shao, Z. & Zhao, H., 2014, In : Current protocols in chemical biology. 6, 2, p. 65-100 36 p.

Research output: Contribution to journalArticle

2015

RNAi-assisted genome evolution in saccharomyces cerevisiae for complex phenotype engineering

Si, T., Luo, Y., Bao, Z. & Zhao, H., Mar 20 2015, In : ACS synthetic biology. 4, 3, p. 283-291 9 p.

Research output: Contribution to journalArticle

2017

Twin-primer non-enzymatic DNA assembly: An efficient and accurate multi-part DNA assembly method

Liang, J., Liu, Z., Ang, E. L. & Zhao, H., 2017, Synthetic Biology Conference, SEED 2017: Engineering, Evolution, and Design. AIChE, p. 45-46 2 p. (Synthetic Biology Conference, SEED 2017: Engineering, Evolution, and Design).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2018

Quantifying the effects of pollen nutrition on honey bee queen egg laying with a new laboratory system

Fine, J. D., Shpigler, H. Y., Ray, A. M., Beach, N. J., Sankey, A. L., Cash-Ahmed, A., Huang, Z. Y., Astrauskaite, I., Chao, R., Zhao, H. & Robinson, G. E., Sep 2018, In : PloS one. 13, 9, e0203444.

Research output: Contribution to journalArticle

2013

Construction and screening of an antigen-derived peptide library displayed on yeast cell surface for CD4+ T cell epitope identification

Wen, F. & Zhao, H., Sep 20 2013, Immunoproteomics: Methods and Protocols. Fulton, K. & Twine, S. (eds.). p. 245-264 20 p. (Methods in Molecular Biology; vol. 1061).

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Engineering biological systems using automated biofoundries

Chao, R., Mishra, S., Si, T. & Zhao, H., Jul 2017, In : Metabolic Engineering. 42, p. 98-108 11 p.

Research output: Contribution to journalReview article

2016

Members of the rusc protein family interact with Sufu and inhibit vertebrate hedgehog signaling

Jin, Z., Schwend, T., Fu, J., Bao, Z., Liang, J., Zhao, H., Mei, W. & Yang, J., Nov 1 2016, In : Development (Cambridge). 143, 21, p. 3944-3955 12 p.

Research output: Contribution to journalArticle

2017

Automated multiplex genome-scale engineering in yeast

Si, T., Chao, R., Min, Y., Wu, Y., Ren, W. & Zhao, H., 2017, In : Nature communications. 8, 15187.

Research output: Contribution to journalArticle

2016

Biocatalysis for Drug Discovery and Development

Liang, Y., Zhang, M. M., Ang, E. L. & Zhao, H., May 13 2016, Green Biocatalysis. Wiley, p. 421-455 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

A coupled chlorinase-fluorinase system with a high efficiency of trans -halogenation and a shared substrate tolerance

Sun, H., Zhao, H. & Ang, E. L., 2018, In : Chemical Communications. 54, 68, p. 9458-9461 4 p.

Research output: Contribution to journalArticle

2010

Structure and Engineering of l-Arabinitol 4-Dehydrogenase from Neurospora crassa

Bae, B., Sullivan, R. P., Zhao, H. & Nair, S. K., Sep 2010, In : Journal of Molecular Biology. 402, 1, p. 230-240 11 p.

Research output: Contribution to journalArticle

2011

Directed evolution of the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo

Evans, B. S., Chen, Y., Metcalf, W. W., Zhao, H. & Kelleher, N. L., May 27 2011, In : Chemistry and Biology. 18, 5, p. 601-607 7 p.

Research output: Contribution to journalArticle

Drug Discovery and Development by Combinatorial Biosynthesis

Desieno, M. A., Denard, C. A. & Zhao, H., May 25 2011, Enzyme Technologies: Metagenomics, Evolution, Biocatalysis, and Biosynthesis. John Wiley and Sons, p. 251-283 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Biochemical and structural investigation of taurine:2-oxoglutarate aminotransferase from Bifidobacterium kashiwanohense

Li, M., Wei, Y., Yin, J., Lin, L., Zhou, Y., Hua, G., Cao, P., Ang, E. L., Zhao, H., Yuchi, Z. & Zhang, Y., Jan 1 2019, In : Biochemical Journal. 476, 11, p. 1605-1619 15 p.

Research output: Contribution to journalArticle

2018

Genome-scale engineering of Saccharomyces cerevisiae with single-nucleotide precision

Bao, Z., HamediRad, M., Xue, P., Xiao, H., Tasan, I., Chao, R., Liang, J. & Zhao, H., Jul 1 2018, In : Nature Biotechnology. 36, 6, p. 505-508 4 p.

Research output: Contribution to journalArticle

2012

A type III polyketide synthase from Rhizobium etli condenses malonyl CoAs to a heptaketide pyrone with unusually high catalytic efficiency

Jeya, M., Kim, T. S., Kumar Tiwari, M., Li, J., Zhao, H. & Lee, J. K., Dec 2012, In : Molecular BioSystems. 8, 12, p. 3103-3106 4 p.

Research output: Contribution to journalArticle

Investigation of the role of Arg301 identified in the X-ray structure of phosphite dehydrogenase

Hung, J. E., Fogle, E. J., Christman, H. D., Johannes, T. W., Zhao, H., Metcalf, W. W. & Van Der Donk, W. A., May 29 2012, In : Biochemistry. 51, 21, p. 4254-4262 9 p.

Research output: Contribution to journalArticle

2017

CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters

Zhang, M. M., Wong, F. T., Wang, Y., Luo, S., Lim, Y. H., Heng, E., Yeo, W. L., Cobb, R. E., Enghiad, B., Ang, E. L. & Zhao, H., Jun 1 2017, In : Nature chemical biology. 13, 6, p. 607-609 3 p.

Research output: Contribution to journalArticle

2012

Recent advances in targeted genome engineering in mammalian systems

Sun, N., Abil, Z. & Zhao, H., Sep 2012, In : Biotechnology Journal. 7, 9, p. 1074-1087 14 p.

Research output: Contribution to journalReview article

2017

Fully Automated One-Step Synthesis of Single-Transcript TALEN Pairs Using a Biological Foundry

Chao, R., Liang, J., Tasan, I., Si, T., Ju, L. & Zhao, H., Apr 21 2017, In : ACS synthetic biology. 6, 4, p. 678-685 8 p.

Research output: Contribution to journalArticle