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  • Yi Lu
2015

Binuclear CuA Formation in Biosynthetic Models of CuA in Azurin Proceeds via a Novel Cu(Cys)2His Mononuclear Copper Intermediate

Chakraborty, S., Polen, M. J., Chacón, K. N., Wilson, T. D., Yu, Y., Reed, J., Nilges, M. J., Blackburn, N. J. & Lu, Y., Oct 6 2015, In : Biochemistry. 54, 39, p. 6071-6081 11 p.

Research output: Contribution to journalArticle

2019

CHAPTER 2: Design and Engineering of Heme Enzymes with O2-dependent Catalytic Activity

Cui, C., Reed, J. H., Mirts, E. N. & Lu, Y., Jan 1 2019, Dioxygen-dependent Heme Enzymes. Ikeda-Saito, M. & Raven, E. (eds.). 13 ed. Royal Society of Chemistry, p. 37-62 26 p. (RSC Metallobiology; vol. 2019-January, no. 13).

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Design of Heteronuclear Metalloenzymes

Bhagi-Damodaran, A., Hosseinzadeh, P., Mirts, E., Reed, J., Petrik, I. D. & Lu, Y., Jan 1 2016, Methods in Enzymology. Academic Press Inc., p. 501-537 37 p. (Methods in Enzymology; vol. 580).

Research output: Chapter in Book/Report/Conference proceedingChapter

A density functional theory protocol for the calculation of redox potentials of copper complexes

Yan, L., Lu, Y. & Li, X., Jan 1 2016, In : Physical Chemistry Chemical Physics. 18, 7, p. 5529-5536 8 p.

Research output: Contribution to journalArticle

2019

Y-Shaped Backbone-Rigidified Triangular DNA Scaffold-Directed Stepwise Movement of a DNAzyme Walker for Sensitive MicroRNA Imaging within Living Cells

Xue, C., Zhang, S., Li, C., Yu, X., Ouyang, C., Lu, Y. & Wu, Z. S., Dec 17 2019, In : Analytical chemistry. 91, 24, p. 15678-15685 8 p.

Research output: Contribution to journalArticle

2012

Metal ion-dependent DNAzymes and their applications as biosensors

Lan, T. & Lu, Y., 2012, In : Metal Ions in Life Sciences. 10, p. 217-248 32 p.

Research output: Contribution to journalArticle

The importance of peripheral sequences in determining the metal selectivity of an in vitro-selected co 2+-Dependent DNAzyme

Nelson, K. E., Ihms, H. E., Mazumdar, D., Bruesehoff, P. J. & Lu, Y., Feb 13 2012, In : ChemBioChem. 13, 3, p. 381-391 11 p.

Research output: Contribution to journalArticle

2011

A novel terpyridine/benzofurazan hybrid fluorophore: Metal sensing behavior and application

Yang, Z., Yan, C., Chen, Y., Zhu, C., Zhang, C., Dong, X., Yang, W., Guo, Z., Lu, Y. & He, W., Mar 14 2011, In : Dalton Transactions. 40, 10, p. 2173-2176 4 p.

Research output: Contribution to journalArticle

2013

Metalloprotein Design

Lu, Y., Chakraborty, S., Miner, K. D., Wilson, T. D., Mukherjee, A., Yu, Y., Liu, J. & Marshall, N. M., Aug 1 2013, Comprehensive Inorganic Chemistry II (Second Edition): From Elements to Applications. Elsevier Ltd, Vol. 3. p. 565-593 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Direct detection of adenosine in undiluted serum using a luminescent aptamer sensor attached to a terbium complex

Li, L. L., Ge, P., Selvin, P. R. & Lu, Y., Sep 18 2012, In : Analytical chemistry. 84, 18, p. 7852-7856 5 p.

Research output: Contribution to journalArticle

2011

Spectroscopic characterization of mononitrosyl complexes in heme-nonheme diiron centers within the myoglobin scaffold (FeBMbs): Relevance to denitrifying No reductase

Hayashi, T., Miner, K. D., Yeung, N., Lin, Y. W., Lu, Y. & Moënne-Loccoz, P., Jul 5 2011, In : Biochemistry. 50, 26, p. 5939-5947 9 p.

Research output: Contribution to journalArticle

2015

Editorial overview: Bioinorganic chemistry: Bioinorganic catalysis for renewable energy

Lim, M. H. & Lu, Y., Apr 1 2015, In : Current Opinion in Chemical Biology. 25, p. vii-viii

Research output: Contribution to journalEditorial

2016

Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities

Bhagi-Damodaran, A., Petrik, I. & Lu, Y., Oct 1 2016, In : Israel Journal of Chemistry. 56, 9-10, p. 773-790 18 p.

Research output: Contribution to journalReview article

2015

Compound Q is finally deciphered

Bhagi-Damodaran, A. & Lu, Y., Sep 1 2015, In : Inorganic Chemistry Frontiers. 2, 9, p. 824-826 3 p.

Research output: Contribution to journalArticle

2014

Functional tuning and expanding of myoglobin by rational protein design

Lin, Y., Wang, J. & Lu, Y., Mar 2014, In : Science China Chemistry. 57, 3, p. 346-355 10 p.

Research output: Contribution to journalReview article

2015

Graphene-DNAzyme junctions: A platform for direct metal ion detection with ultrahigh sensitivity

Gao, L., Li, L. L., Wang, X., Wu, P., Cao, Y., Liang, B., Li, X., Lin, Y., Lu, Y. & Guo, X., Apr 1 2015, In : Chemical Science. 6, 4, p. 2469-2473 5 p.

Research output: Contribution to journalArticle

Jun-Long Zhang

Zhang, J. L., Che, C. M. & Lu, Y., Jan 2015, In : ChemPlusChem. 80, 1, 1 p.

Research output: Contribution to journalComment/debate

2013

Metal ion as both a cofactor and a probe of metal-binding sites in a uranyl-specific DNAzyme: A uranyl photocleavage study

Cepeda-Plaza, M., Null, E. L. & Lu, Y., Nov 1 2013, In : Nucleic acids research. 41, 20, p. 9361-9370 10 p.

Research output: Contribution to journalArticle

2014

Copper-sulfenate complex from oxidation of a cavity mutant of pseudomonas aeruginosa azurin

Sieracki, N. A., Tian, S., Hadt, R. G., Zhang, J. L., Woertink, J. S., Nilges, M. J., Sun, F., Solomon, E. I. & Lu, Y., Jan 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 924-929 6 p.

Research output: Contribution to journalArticle

2016

Design of a single protein that spans the entire 2-V range of physiological redox potentials

Hosseinzadeh, P., Marshall, N. M., Chacón, K. N., Yu, Y., Nilges, M. J., New, S. Y., Tashkov, S. A., Blackburn, N. J. & Lu, Y., Jan 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 2, p. 262-267 6 p.

Research output: Contribution to journalArticle

2013
2017

Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme–Catalytic Hairpin Assembly Probe

Wu, Z., Fan, H., Satyavolu, N. S. R., Wang, W. J., Lake, R., Jiang, J. H. & Lu, Y., Jul 17 2017, In : Angewandte Chemie - International Edition. 56, 30, p. 8721-8725 5 p.

Research output: Contribution to journalArticle

2020

Independent control over size, valence, and elemental composition in the synthesis of DNA-nanoparticle conjugates

Bai, Y., Xing, H., Bai, Y., Tan, L. H., Hwang, K., Li, J., Lu, Y. & Zimmerman, S. C., Feb 14 2020, In : Chemical Science. 11, 6, p. 1564-1572 9 p.

Research output: Contribution to journalArticle

Open Access
2019

Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors

Hwang, K., Mou, Q., Lake, R. J., Xiong, M., Holland, B. & Lu, Y., Oct 21 2019, In : Inorganic Chemistry. 58, 20, p. 13696-13708 13 p.

Research output: Contribution to journalReview article

2017

Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism

Reed, J. H., Shi, Y., Zhu, Q., Chakraborty, S., Mirts, E. N., Petrik, I. D., Bhagi-Damodaran, A., Ross, M., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Sep 6 2017, In : Journal of the American Chemical Society. 139, 35, p. 12209-12218 10 p.

Research output: Contribution to journalArticle

2011

A smart magnetic resonance imaging contrast agent responsive to adenosine based on a DNA aptamer-conjugated gadolinium complex

Xu, W. & Lu, Y., May 7 2011, In : Chemical Communications. 47, 17, p. 4998-5000 3 p.

Research output: Contribution to journalArticle

2016

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

Zhang, J. J., Cheng, F. F., Li, J. J., Zhu, J. J. & Lu, Y., Jun 1 2016, In : Nano Today. 11, 3, p. 309-329 21 p.

Research output: Contribution to journalReview article

2018

Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles

Yang, Z., Loh, K. Y., Chu, Y. T., Feng, R., Satyavolu, N. S. R., Xiong, M., Nakamata Huynh, S. M., Hwang, K., Li, L., Xing, H., Zhang, X., Chemla, Y. R., Gruebele, M. & Lu, Y., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17656-17665 10 p.

Research output: Contribution to journalArticle

Translating molecular detections into a simple temperature test using a target-responsive smart thermometer

Zhang, J., Xing, H. & Lu, Y., Jan 1 2018, In : Chemical Science. 9, 16, p. 3906-3910 5 p.

Research output: Contribution to journalArticle

2012

Functional protein microarrays by electrohydrodynamic jet printing

Shigeta, K., He, Y., Sutanto, E., Kang, S., Le, A. P., Nuzzo, R. G., Alleyne, A. G., Ferreira, P. M., Lu, Y. & Rogers, J. A., Nov 20 2012, In : Analytical chemistry. 84, 22, p. 10012-10018 7 p.

Research output: Contribution to journalArticle

2019

Discovery of and Insights into DNA “Codes” for Tunable Morphologies of Metal Nanoparticles

Satyavolu, N. S. R., Loh, K. Y., Tan, L. H. & Lu, Y., Jun 26 2019, In : Small. 15, 26, 1900975.

Research output: Contribution to journalReview article

2015

Nanomaterial-based biosensors using dual transducing elements for solution phase detection

Li, N., Su, X. & Lu, Y., May 7 2015, In : Analyst. 140, 9, p. 2916-2943 28 p.

Research output: Contribution to journalReview article

2012

Significant increase of oxidase activity through the genetic incorporation of a tyrosine-histidine cross-link in a myoglobin model of heme-copper oxidase

Liu, X., Yu, Y., Hu, C., Zhang, W., Lu, Y. & Wang, J., Apr 27 2012, In : Angewandte Chemie - International Edition. 51, 18, p. 4312-4316 5 p.

Research output: Contribution to journalArticle

2013

A smart T1-weighted MRI contrast agent for uranyl cations based on a DNAzyme-gadolinium conjugate

Xu, W., Xing, H. & Lu, Y., Nov 7 2013, In : Analyst. 138, 21, p. 6266-6269 4 p.

Research output: Contribution to journalArticle

Enhanced and tunable fluorescent quantum dots within a single crystal of protein

Wei, H., House, S., Wu, J., Zhang, J., Wang, Z., He, Y., Gao, E. J., Gao, Y., Robinson, H., Li, W., Zuo, J-M., Robertson, I. M. & Lu, Y., Sep 1 2013, In : Nano Research. 6, 9, p. 627-634 8 p.

Research output: Contribution to journalArticle

2019

Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter

Xu, J., Qiao, X., Zhang, J., Cheng, N., Sheng, Q., Zheng, J., Cao, W., Yue, T. & Lu, Y., Apr 14 2019, In : Analytical Methods. 11, 14, p. 1849-1856 8 p.

Research output: Contribution to journalArticle

Cupredoxin engineered upconversion nanoparticles for ratiometric luminescence sensing of Cu2+

Liu, C., Yu, Y., Chen, D., Zhao, J., Yu, Y., Li, L. & Lu, Y., Jan 1 2019, In : Nanoscale Advances. 1, 7, p. 2580-2585 6 p.

Research output: Contribution to journalArticle

Open Access
2014

Applications of synchrotron-based spectroscopic techniques in studying nucleic acids and nucleic acid-functionalized nanomaterials

Wu, P., Yu, Y., McGhee, C. E., Tan, L. H. & Lu, Y., Dec 10 2014, In : Advanced Materials. 26, 46, p. 7849-7872 24 p.

Research output: Contribution to journalArticle

Direct EPR observation of a tyrosyl radical in a functional oxidase model in myoglobin during both H2O2 and O2 reactions

Yu, Y., Mukherjee, A., Nilges, M. J., Hosseinzadeh, P., Miner, K. D. & Lu, Y., Jan 29 2014, In : Journal of the American Chemical Society. 136, 4, p. 1174-1177 4 p.

Research output: Contribution to journalArticle

2016

Reversible S-nitrosylation in an engineered azurin

Tian, S., Liu, J., Cowley, R. E., Hosseinzadeh, P., Marshall, N. M., Yu, Y., Robinson, H., Nilges, M. J., Blackburn, N. J., Solomon, E. I. & Lu, Y., Jul 1 2016, In : Nature Chemistry. 8, 7, p. 670-677 8 p.

Research output: Contribution to journalArticle

2014

The production of nitrous oxide by the heme/nonheme diiron center of engineered myoglobins (FeBMbs) proceeds through a trans -iron-nitrosyl dimer

Matsumura, H., Hayashi, T., Chakraborty, S., Lu, Y. & Moënne-Loccoz, P., Feb 12 2014, In : Journal of the American Chemical Society. 136, 6, p. 2420-2431 12 p.

Research output: Contribution to journalArticle

2011
2017

Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases

Bhagi-Damodaran, A., Michael, M. A., Zhu, Q., Reed, J., Sandoval, B. A., Mirts, E. N., Chakraborty, S., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Mar 1 2017, In : Nature Chemistry. 9, 3, p. 257-263 7 p.

Research output: Contribution to journalArticle

2014

DNA aptamer technology for personalized medicine

Xing, H., Hwang, K., Li, J., Torabi, S. F. & Lu, Y., May 2014, In : Current Opinion in Chemical Engineering. 4, p. 79-87 9 p.

Research output: Contribution to journalReview article

2016

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

Hwang, K., Hosseinzadeh, P. & Lu, Y., Jan 1 2016, In : Inorganica Chimica Acta. 452, p. 12-24 13 p.

Research output: Contribution to journalReview article

2013

An invasive DNA approach toward a general method for portable quantification of metal ions using a personal glucose meter

Xiang, Y. & Lu, Y., Jan 21 2013, In : Chemical Communications. 49, 6, p. 585-587 3 p.

Research output: Contribution to journalArticle

2017

DNAzyme sensors for detection of metal ions in the environment and imaging them in living cells

McGhee, C. E., Loh, K. Y. & Lu, Y., Jun 1 2017, In : Current Opinion in Biotechnology. 45, p. 191-201 11 p.

Research output: Contribution to journalReview article

2011

The important role of covalent anchor positions in tuning catalytic properties of a rationally designed Mnsalen-containing metalloenzyme

Garner, D. K., Liang, L., Barrios, D. A., Zhang, J. L. & Lu, Y., Sep 2 2011, In : ACS Catalysis. 1, 9, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

2015

A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification

Pallares, R. M., Kong, S. L., Hui Ru, T., Thanh, N. T. K., Lu, Y. & Su, X., Aug 6 2015, In : Chemical Communications. 51, 77, p. 14524-14527 4 p.

Research output: Contribution to journalArticle