Find Research Outputs

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Huimin Zhao
2016

ACS Catalysis and the Scope of Papers Sought in Three Catalysis Subdisciplines: Biocatalysis and Enzymology, Molecular Catalysis for Organic Synthesis, and Heterogeneous Photocatalysis

Chang, S., Fornasiero, P., Gunnoe, T. B., Jones, C. W., Linic, S., Ooi, T., Williams, R. M. & Zhao, H., Jul 1 2016, In : ACS Catalysis. 6, 7, p. 4782-4785 4 p.

Research output: Contribution to journalReview article

2017

A plug-and-play pathway refactoring workflow for natural product research in Escherichia coli and Saccharomyces cerevisiae

Ren, H., Hu, P. & Zhao, H., Aug 2017, In : Biotechnology and bioengineering. 114, 8, p. 1847-1854 8 p.

Research output: Contribution to journalArticle

2018

Cooperative asymmetric reactions combining photocatalysis and enzymatic catalysis

Litman, Z. C., Wang, Y., Zhao, H. & Hartwig, J. F., Aug 16 2018, In : Nature. 560, 7718, p. 355-359 5 p.

Research output: Contribution to journalLetter

2013

Construction and engineering of large biochemical pathways via DNA assembler

Shao, Z. & Zhao, H., Sep 20 2013, Synthetic Biology. Polizzi, K. & Kontoravdi, C. (eds.). p. 85-106 22 p. (Methods in Molecular Biology; vol. 1073).

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

New tools for reconstruction and heterologous expression of natural product biosynthetic gene clusters

Luo, Y., Enghiad, B. & Zhao, H., Feb 2016, In : Natural Product Reports. 33, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

2019

An efficient gene knock-in strategy using 5′-modified double-stranded DNA donors with short homology arms

Yu, Y., Guo, Y., Tian, Q., Lan, Y., Yeh, H., Zhang, M., Tasan, I., Jain, S. & Zhao, H., Dec 23 2019, (Accepted/In press) In : Nature chemical biology.

Research output: Contribution to journalArticle

2014

A two-plasmid bacterial selection system for characterization and engineering of homing endonucleases

Sun, N. & Zhao, H., 2014, Homing Endonucleases: Methods and Protocols. Humana Press Inc., p. 87-96 10 p. (Methods in Molecular Biology; vol. 1123).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Cloning and characterization of a type III polyketide synthase from Aspergillus niger

Li, J., Luo, Y., Lee, J. K. & Zhao, H., Oct 15 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 20, p. 6085-6089 5 p.

Research output: Contribution to journalArticle

2013

Directed evolution as a powerful synthetic biology tool

Cobb, R. E., Sun, N. & Zhao, H., Mar 15 2013, In : Methods. 60, 1, p. 81-90 10 p.

Research output: Contribution to journalReview article

2012

DNA assembler: A synthetic biology tool for characterizing and engineering natural product gene clusters

Shao, Z. & Zhao, H., 2012, Natural Product Biosynthesis by Microorganisms and Plants, Part C. Academic Press Inc., p. 203-224 22 p. (Methods in Enzymology; vol. 517).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine

Yin, J., Wei, Y., Liu, D., Hu, Y., Lu, Q., Lui Ang, E., Zhao, H. & Zhang, Y., Jan 1 2019, In : Journal of Biological Chemistry. 294, 43, p. 15662-15671 10 p.

Research output: Contribution to journalArticle

2020

Computational Tools for Discovering and Engineering Natural Product Biosynthetic Pathways

Ren, H., Shi, C. & Zhao, H., Jan 24 2020, In : iScience. 23, 1, 100795.

Research output: Contribution to journalReview article

Open Access
2013

Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production

Rao, G., Lee, J. K. & Zhao, H., Jul 1 2013, In : Applied Microbiology and Biotechnology. 97, 13, p. 5861-5867 7 p.

Research output: Contribution to journalArticle

2016

Editorial: Synthetic biology and bioinformatics

Medema, M. H. & Zhao, H., Aug 2016, In : Natural Product Reports. 33, 8, p. 913-914 2 p.

Research output: Contribution to journalEditorial

2011

Genome-scale consequences of cofactor balancing in engineered pentose utilization pathways in Saccharomyces cerevisiae

Ghosh, A., Zhao, H. & Price, N. D., Nov 4 2011, In : PloS one. 6, 11, e27316.

Research output: Contribution to journalArticle

2019

A gene cluster for taurine sulfur assimilation in an anaerobic human gut bacterium

Xing, M., Wei, Y., Hua, G., Li, M., Nanjaraj Urs, A. N., Wang, F., Hu, Y., Zhai, W., Liu, Y., Ang, E. L., Zhao, H. & Zhang, Y., Aug 15 2019, In : Biochemical Journal. 476, 15, p. 2271-2279 9 p.

Research output: Contribution to journalArticle

2018

Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface

Limsakul, P., Peng, Q., Wu, Y., Allen, M. E., Liang, J., Remacle, A. G., Lopez, T., Ge, X., Kay, B. K., Zhao, H., Strongin, A. Y., Yang, X. L., Lu, S. & Wang, Y., Apr 19 2018, In : Cell chemical biology. 25, 4, p. 370-379.e4

Research output: Contribution to journalArticle

2013

Customized optimization of metabolic pathways by combinatorial transcriptional engineering.

Yuan, Y., Du, J. & Zhao, H., Aug 2 2013, In : Methods in molecular biology (Clifton, N.J.). 985, p. 177-209 33 p.

Research output: Contribution to journalArticle

2012

Recent advances in targeted genome engineering in mammalian systems

Sun, N., Abil, Z. & Zhao, H., Sep 1 2012, In : Biotechnology Journal. 7, 9, p. 1074-1087 14 p.

Research output: Contribution to journalReview article

2016

Accelerated genome engineering through multiplexing

Bao, Z., Cobb, R. E. & Zhao, H., Jan 1 2016, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 8, 1, p. 5-21 17 p.

Research output: Contribution to journalReview article

2019

Author Correction: Building a global alliance of biofoundries (Nature Communications, (2019), 10, 1, (2040), 10.1038/s41467-019-10079-2)

Hillson, N., Caddick, M., Cai, Y., Carrasco, J. A., Chang, M. W., Curach, N. C., Bell, D. J., Feuvre, R. L., Friedman, D. C., Fu, X., Gold, N. D., Herrgård, M. J., Holowko, M. B., Johnson, J. R., Johnson, R. A., Keasling, J. D., Kitney, R. I., Kondo, A., Liu, C., Martin, V. J. J. & 16 others, Menolascina, F., Ogino, C., Patron, N. J., Pavan, M., Poh, C. L., Pretorius, I. S., Rosser, S. J., Scrutton, N. S., Storch, M., Tekotte, H., Travnik, E., Vickers, C. E., Yew, W. S., Yuan, Y., Zhao, H. & Freemont, P. S., Dec 1 2019, In : Nature communications. 10, 1, 3132.

Research output: Contribution to journalComment/debate

Open Access
2015

Direct observation of TALE protein dynamics reveals a two-state search mechanism

Cuculis, L., Abil, Z., Zhao, H. & Schroeder, C. M., Jun 1 2015, In : Nature communications. 6, 7277.

Research output: Contribution to journalArticle

2018

CRISPR/Cas9-mediated knock-in of an optimized TetO repeat for live cell imaging of endogenous loci

Tasan, I., Sustackova, G., Zhang, L., Kim, J., Sivaguru, M., HamediRad, M., Wang, Y., Genova, J., Ma, J., Belmont, A. S. & Zhao, H., Jan 1 2018, In : Nucleic acids research. 46, 17, e100.

Research output: Contribution to journalArticle

Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole

Liu, D., Wei, Y., Liu, X., Zhou, Y., Jiang, L., Yin, J., Wang, F., Hu, Y., Nanjaraj Urs, A. N., Liu, Y., Ang, E. L., Zhao, S., Zhao, H. & Zhang, Y., Dec 1 2018, In : Nature communications. 9, 1, 4224.

Research output: Contribution to journalArticle

2014

Comparative biochemical characterization of three exolytic oligoalginate lyases from Vibrio splendidus reveals complementary substrate scope, temperature, and pH adaptations

Jagtap, S. S., Hehemann, J. H., Polz, M. F., Lee, J. K. & Zhao, H., 2014, In : Applied and environmental microbiology. 80, 14, p. 4207-4214 8 p.

Research output: Contribution to journalArticle

2015

Engineered biosynthesis of natural products in heterologous hosts

Luo, Y., Li, B. Z., Liu, D., Zhang, L., Chen, Y., Jia, B., Zeng, B. X., Zhao, H. & Yuan, Y. J., Aug 7 2015, In : Chemical Society Reviews. 44, 15, p. 5265-5290 26 p.

Research output: Contribution to journalArticle

2016

Use of genome-editing tools to treat sickle cell disease

Tasan, I., Jain, S. & Zhao, H., Sep 1 2016, In : Human Genetics. 135, 9, p. 1011-1028 18 p.

Research output: Contribution to journalReview article

2018

Recent developments in the application of P450 based biocatalysts

Wei, Y., Ang, E. L. & Zhao, H., Apr 2018, In : Current Opinion in Chemical Biology. 43, p. 1-7 7 p.

Research output: Contribution to journalReview article

2015
2011

Further biochemical studies on aminopyrrolnitrin oxygenase (PrnD)

Tiwari, M. K., Lee, J. K., Moon, H. J. & Zhao, H., May 15 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 10, p. 2873-2876 4 p.

Research output: Contribution to journalArticle

2015

Recent advances in DNA assembly technologies

Chao, R., Yuan, Y. & Zhao, H., Jan 1 2015, In : FEMS yeast research. 15, 1, 12171.

Research output: Contribution to journalShort survey

2019

Development of a CRISPR/Cas9 system for high efficiency multiplexed gene deletion in Rhodosporidium toruloides

Schultz, J. C., Cao, M. & Zhao, H., Aug 2019, In : Biotechnology and bioengineering. 116, 8, p. 2103-2109 7 p.

Research output: Contribution to journalArticle

2017

Combining Rh-Catalyzed Diazocoupling and Enzymatic Reduction to Efficiently Synthesize Enantioenriched 2-Substituted Succinate Derivatives

Wang, Y., Bartlett, M. J., Denard, C. A., Hartwig, J. F. & Zhao, H., Apr 7 2017, In : ACS Catalysis. 7, 4, p. 2548-2552 5 p.

Research output: Contribution to journalArticle

2011

Characterization and application of the Fe(ii) and α-ketoglutarate dependent hydroxylase FrbJ

Desieno, M. A., Van Der Donk, W. A. & Zhao, H., Sep 28 2011, In : Chemical Communications. 47, 36, p. 10025-10027 3 p.

Research output: Contribution to journalArticle

2013

Challenges and opportunities in synthetic biology for chemical engineers

Luo, Y., Lee, J. K. & Zhao, H., Nov 5 2013, In : Chemical Engineering Science. 103, p. 115-119 5 p.

Research output: Contribution to journalArticle

2014

Exploiting Issatchenkia orientalis SD108 for succinic acid production

Xiao, H., Shao, Z., Jiang, Y., Dole, S. & Zhao, H., Aug 27 2014, In : Microbial cell factories. 13, 1, 121.

Research output: Contribution to journalReview article

2019

Highly Efficient Single-Pot Scarless Golden Gate Assembly

Hamedirad, M., Weisberg, S., Chao, R., Lian, J. & Zhao, H., May 17 2019, In : ACS synthetic biology. 8, 5, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

2015

In Situ Assembly of Antifouling/Bacterial Silver Nanoparticle-Hydrogel Composites with Controlled Particle Release and Matrix Softening

Baek, K., Liang, J., Lim, W. T., Zhao, H., Kim, D. H. & Kong, H., Jul 22 2015, In : ACS Applied Materials and Interfaces. 7, 28, p. 15359-15367 9 p.

Research output: Contribution to journalArticle

2014

Homology-integrated CRISPR-cas (HI-CRISPR) system for one-step multigene disruption in saccharomyces cerevisiae

Bao, Z., Xiao, H., Liang, J., Zhang, L., Xiong, X., Sun, N., Si, T. & Zhao, H., Jan 1 2014, Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. AIChE, p. 27-36 10 p. (Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area at the 2014 AIChE Annual Meeting; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2016
2013

Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold

Shao, Z., Rao, G., Li, C., Abil, Z., Luo, Y. & Zhao, H., Nov 15 2013, In : ACS synthetic biology. 2, 11, p. 662-669 8 p.

Research output: Contribution to journalArticle

Investigating xylose metabolism in recombinant Saccharomyces cerevisiae via 13C metabolic flux analysis

Feng, X. & Zhao, H., Nov 18 2013, In : Microbial cell factories. 12, 1, 114.

Research output: Contribution to journalArticle

2015

Selective elimination of mitochondrial mutations in the germline by genome editing

Reddy, P., Ocampo, A., Suzuki, K., Luo, J., Bacman, S. R., Williams, S. L., Sugawara, A., Okamura, D., Tsunekawa, Y., Wu, J., Lam, D., Xiong, X., Montserrat, N., Esteban, C. R., Liu, G. H., Sancho-Martinez, I., Manau, D., Civico, S., Cardellach, F., Del Mar O'Callaghan, M. & 5 others, Campistol, J., Zhao, H., Campistol, J. M., Moraes, C. T. & Izpisua Belmonte, J. C., Apr 23 2015, In : Cell. 161, 3, p. 459-469 11 p.

Research output: Contribution to journalArticle

2012

Role of conserved glycine in zinc-dependent medium chain dehydrogenase/reductase superfamily

Tiwari, M. K., Singh, R. K., Singh, R., Jeya, M., Zhao, H. & Lee, J. K., Jun 1 2012, In : Journal of Biological Chemistry. 287, 23, p. 19429-19439 11 p.

Research output: Contribution to journalArticle

2016

Engineered minicellulosomes for consolidated bioprocessing

Liang, Y., Ang, E. L. & Zhao, H., Jul 11 2016, Handbook of Carbohydrate-Modifying Biocatalysts. Pan Stanford Publishing Pte. Ltd., Vol. 2. p. 965-992 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Protein design for pathway engineering

Eriksen, D. T., Lian, J. & Zhao, H., Feb 1 2014, In : Journal of Structural Biology. 185, 2, p. 234-242 9 p.

Research output: Contribution to journalArticle

2017

Twin-primer non-enzymatic DNA assembly: An efficient and accurate multi-part DNA assembly method

Liang, J., Liu, Z., Low, X. Z., Ang, E. L. & Zhao, H., Jun 1 2017, In : Nucleic acids research. 45, 11, p. e94

Research output: Contribution to journalArticle

2013

Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster

Luo, Y., Huang, H., Liang, J., Wang, M., Lu, L., Shao, Z., Cobb, R. E. & Zhao, H., Dec 5 2013, In : Nature communications. 4, 2894.

Research output: Contribution to journalArticle

2019

Identification and Characterization of Citrus Peel Uronic Acid Oxidase

Wei, Y., Tan, Y. L., Ang, E. L. & Zhao, H., Jan 1 2019, (Accepted/In press) In : ChemBioChem.

Research output: Contribution to journalArticle

2015

A Rewritable, Random-Access DNA-Based Storage System

Tabatabaei Yazdi, S. M. H., Yuan, Y., Ma, J., Zhao, H. & Milenkovic, O., Sep 18 2015, In : Scientific reports. 5, 14138.

Research output: Contribution to journalArticle