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  • Benita S Katzenellenbogen
2015

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In : Nature communications. 6, 8303.

Research output: Contribution to journalArticle

Protective hematopoietic effect of estrogens in a mouse model of thrombosis: Respective roles of nuclear versus membrane estrogen receptor α

Valera, M. C., Fontaine, C., Lenfant, F., Cabou, C., Guillaume, M., Smirnova, N., Kim, S. H., Chambon, P., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Payrastre, B. & Arnal, J. F., Nov 2015, In : Endocrinology. 156, 11, p. 4293-4301 9 p.

Research output: Contribution to journalArticle

2012
2017

Full antagonism of the estrogen receptor without a prototypical ligand side chain

Srinivasan, S., Nwachukwu, J. C., Bruno, N. E., Dharmarajan, V., Goswami, D., Kastrati, I., Novick, S., Nowak, J., Cavett, V., Zhou, H. B., Boonmuen, N., Zhao, Y., Min, J., Frasor, J., Katzenellenbogen, B. S., Griffin, P. R., Katzenellenbogen, J. A. & Nettles, K. W., Jan 1 2017, In : Nature chemical biology. 13, 1, p. 111-118 8 p.

Research output: Contribution to journalArticle

2016

Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities

Boonmuen, N., Gong, P., Ali, Z., Chittiboyina, A. G., Khan, I., Doerge, D. R., Helferich, W. G., Carlson, K. E., Martin, T., Piyachaturawat, P., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2016, In : Steroids. 105, p. 42-49 8 p.

Research output: Contribution to journalArticle

Multiple beneficial roles of repressor of estrogen receptor activity (REA) in suppressing the progression of endometriosis

Zhao, Y., Chen, Y., Kuang, Y., Bagchi, M. K., Taylor, R. N., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Feb 2016, In : Endocrinology. 157, 2, p. 900-912 13 p.

Research output: Contribution to journalArticle

2018

Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: Implications for ERα modulation

Vinel, A., Coudert, A. E., Buscato, M., Valera, M. C., Ostertag, A., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Berdal, A., Babajko, S., Arnal, J. F. & Fontaine, C., Aug 2018, In : Journal of Bone and Mineral Research. 33, 8, p. 1520-1531 12 p.

Research output: Contribution to journalArticle

2016

Science Signaling podcast for 24 May 2016: Designer estrogens

Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In : Science Signaling. 9, 429, pc13.

Research output: Contribution to journalReview article

2019

Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In : npj Breast Cancer. 5, 1, 45.

Research output: Contribution to journalArticle

Open Access
2013

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In : Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journalArticle

2016

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

Madak-Erdogan, Z., Kim, S. H., Gong, P., Zhao, Y. C., Zhang, H., Chambliss, K. L., Carlson, K. E., Mayne, C. G., Shaul, P. W., Korach, K. S., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., May 24 2016, In : Science Signaling. 9, 429, ra53.

Research output: Contribution to journalArticle

2018

Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

Selvaraj, U. M., Zuurbier, K. R., Whoolery, C. W., Plautz, E. J., Chambliss, K. L., Kong, X., Zhang, S., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C., Shaul, P. W. & Stowe, A. M., 2018, In : Endocrinology. 159, 11, p. 3848-3859 12 p.

Research output: Contribution to journalArticle

2017

Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice

Menazza, S., Sun, J., Appachi, S., Chambliss, K. L., Kim, S. H., Aponte, A., Khan, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Shaul, P. W. & Murphy, E., Jun 1 2017, In : Journal of Molecular and Cellular Cardiology. 107, p. 41-51 11 p.

Research output: Contribution to journalArticle

2018

Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice

Miranda, C. L., Johnson, L. A., De Montgolfier, O., Elias, V. D., Ullrich, L. S., Hay, J. J., Paraiso, I. L., Choi, J., Reed, R. L., Revel, J. S., Kioussi, C., Bobe, G., Iwaniec, U. T., Turner, R. T., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Blakemore, P. R., Gombart, A. F., Maier, C. S., Raber, J. & 1 others, Stevens, J. F., Dec 1 2018, In : Scientific reports. 8, 1, 613.

Research output: Contribution to journalArticle

2020

Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors

Laws, M. J., Ziegler, Y., Shahoei, S. H., Dey, P., Kim, S. H., Yasuda, M., Park, B. H., Nettles, K. W., Katzenellenbogen, J. A., Nelson, E. R. & Katzenellenbogen, B. S., Jun 1 2020, In : Breast Cancer Research and Treatment. 181, 2, p. 297-307 11 p.

Research output: Contribution to journalArticle

2014
2012

Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In : Oncogene. 31, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

2014

Highly sensitive quantitative imaging for monitoring single cancer cell growth kinetics and drug response

Mir, M., Bergamaschi, A., Katzenellenbogen, B. S. & Popescu, G., Feb 18 2014, In : PloS one. 9, 2, e89000.

Research output: Contribution to journalArticle

2016
2011

Estrogen-regulated prohibitin is required for mouse uterine development and adult function

He, B., Kim, T. H., Kommagani, R., Feng, Q., Lanz, R. B., Jeong, J. W., DeMayo, F. J., Katzenellenbogen, B. S., Lydon, J. P. & O'Malley, B. W., Mar 2011, In : Endocrinology. 152, 3, p. 1047-1056 10 p.

Research output: Contribution to journalArticle

2014
2017

Membrane and nuclear estrogen receptor alpha actions: From tissue specificity to medical implications

Arnal, J. F., Lenfant, F., Metivier, R., Flouriot, G., Henrion, D., Adlanmerini, M., Fontaine, C., Gourdy, P., Chambon, P., Katzenellenbogen, B. & Katzenellenbogen, J., Jul 2017, In : Physiological Reviews. 97, 3, p. 1045-1087 43 p.

Research output: Contribution to journalReview article

Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors

Zhao, Y., Laws, M. J., Guillen, V. S., Ziegler, Y., Min, J., Sharma, A., Kim, S. H., Chu, D., Park, B. H., Oesterreich, S., Mao, C., Shapiro, D. J., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5602-5613 12 p.

Research output: Contribution to journalArticle

2013

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

Jiang, Y., Gong, P., Madak-Erdogan, Z., Martin, T., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T. J., Chittiboyina, A. G., Rotte, S. C. K., Helferich, W. G., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Nov 2013, In : FASEB Journal. 27, 11, p. 4406-4418 13 p.

Research output: Contribution to journalArticle

2017

Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms

Martin, A., Yu, J., Xiong, J., Khalid, A. B., Katzenellenbogen, B., Kim, S. H., Katzenellenbogen, J. A., Malaivijitnond, S., Gabet, Y., Krum, S. A. & Frenkel, B., Dec 2017, In : Journal of Cellular Physiology. 232, 12, p. 3798-3807 10 p.

Research output: Contribution to journalArticle

2014
2016

Endocrine treatment in breast cancer: Cure, resistance and beyond

Tryfonidis, K., Zardavas, D., Katzenellenbogen, B. S. & Piccart, M., Nov 1 2016, In : Cancer Treatment Reviews. 50, p. 68-81 14 p.

Research output: Contribution to journalReview article

2018

Predominant role of nuclear versus membrane estrogen receptor α in arterial protection: Implications for estrogen receptor α modulation in cardiovascular prevention/safety

Guivarc’h, E., Buscato, M., Guihot, A. L., Favre, J., Vessières, E., Grimaud, L., Wakim, J., Melhem, N. J., Zahreddine, R., Adlanmerini, M., Loufrani, L., Knauf, C., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Foidart, J. M., Gourdy, P., Lenfant, F., Arnal, J. F., Henrion, D. & Fontaine, C., Jul 1 2018, In : Journal of the American Heart Association. 7, 13, e008950.

Research output: Contribution to journalArticle

2012
2011

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In : Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

Estrogen receptor β ligands: Recent advances and biomedical applications

Minutolo, F., Macchia, M., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., May 1 2011, In : Medicinal Research Reviews. 31, 3, p. 364-442 79 p.

Research output: Contribution to journalArticle

2016

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

Fanning, S. W., Mayne, C. G., Dharmarajan, V., Carlson, K. E., Martin, T. A., Novick, S. J., Toy, W., Green, B., Panchamukhi, S., Katzenellenbogen, B. S., Tajkhorshid, E., Griffin, P. R., Shen, Y., Chandarlapaty, S., Katzenellenbogen, J. A. & Greene, G. L., Feb 2 2016, In : eLife. 5, FEBRUARY2016, e12792.

Research output: Contribution to journalArticle

2013

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

Madak-Erdogan, Z., Charn, T. H., Jiang, Y., Liu, E. T., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., 2013, In : Molecular Systems Biology. 9, 201328.

Research output: Contribution to journalArticle

2014

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Jan 1 2014, In : In Vitro Cellular and Developmental Biology - Animal. 51, 1, p. 59-71 13 p.

Research output: Contribution to journalArticle

Estrogen-induced CCN1 Is critical for establishment of endometriosis-like lesions in mice

Zhao, Y., Li, Q., Katzenellenbogen, B. S., Lau, L. F., Taylor, R. N., Bagchi, I. C. & Bagchi, M. K., 2014, In : Molecular Endocrinology. 28, 12, p. 1934-1947 14 p.

Research output: Contribution to journalArticle

2020

The tissue-specific effects of different 17β-estradiol doses reveal the key sensitizing role of AF1 domain in ERα activity

Fontaine, C., Buscato, M., Vinel, A., Giton, F., Raymond-Letron, I., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Gourdy, P., Milon, A., Flouriot, G., Ohlsson, C., Lenfant, F. & Arnal, J. F., Apr 5 2020, In : Molecular and Cellular Endocrinology. 505, 110741.

Research output: Contribution to journalArticle

2016

OCT-4: A novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells

Bhatt, S., Stender, J. D., Joshi, S., Wu, G. & Katzenellenbogen, B. S., Nov 3 2016, In : Oncogene. 35, 44, p. 5722-5734 13 p.

Research output: Contribution to journalArticle

2018

Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

Katzenellenbogen, J. A., Mayne, C. G., Katzenellenbogen, B. S., Greene, G. L. & Chandarlapaty, S., Jun 1 2018, In : Nature Reviews Cancer. 18, 6, p. 377-388 12 p.

Research output: Contribution to journalReview article

2017
2015

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

Paterni, I., Bertini, S., Granchi, C., Tuccinardi, T., Macchia, M., Martinelli, A., Caligiuri, I., Toffoli, G., Rizzolio, F., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Minutolo, F., Feb 12 2015, In : Journal of Medicinal Chemistry. 58, 3, p. 1184-1194 11 p.

Research output: Contribution to journalArticle

2013
2016

Nonnuclear estrogen receptor activation improves hepatic steatosis in female mice

Chambliss, K. L., Barrera, J., Umetani, M., Umetani, J., Kim, S. H., Madak-Erdogan, Z., Huang, L., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C. & Shaul, P. W., 2016, In : Endocrinology. 157, 10, p. 3731-3741 11 p.

Research output: Contribution to journalArticle

2018

Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain

Sharma, A., Toy, W., Guillen, V. S., Sharma, N., Min, J., Carlson, K. E., Mayne, C. G., Lin, S., Sabio, M., Greene, G., Katzenellenbogen, B. S., Chandarlapaty, S. & Katzenellenbogen, J. A., Dec 21 2018, In : ACS chemical biology. 13, 12, p. 3374-3384 11 p.

Research output: Contribution to journalArticle

2014

Endocrine Society 2014 Laureate Awards

Gustafsson, J. A., Katzenellenbogen, B., Jameson, J. L., Roth, J., Melmed, S., McDonnell, D., Wartofsky, L., Crowley, W. F., Griz, L. H. E., Becker, C., Moore, D. D., Drucker, D., Singh, N. & O'Malley, B., Oct 1 2014, In : Hormones & cancer. 5, 5, p. 339-355 17 p.

Research output: Contribution to journalArticle

Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells

Clark, S., Rainville, J., Zhao, X., Katzenellenbogen, B. S., Pfaff, D. & Vasudevan, N., Jan 1 2014, In : Journal of Steroid Biochemistry and Molecular Biology. 139, p. 45-53 9 p.

Research output: Contribution to journalArticle

2020

Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers

Cotul, E. K., Zuo, Q., Santaliz-Casiano, A., Imir, O. B., Mogol, A. N., Tunc, E., Duong, K., Lee, J. K., Ramesh, R., Odukoya, E., Kesavadas, M. P., Ziogaite, M., Smith, B. P., Mao, C., Shapiro, D. J., Park, B. H., Katzenellenbogen, B. S., Daly, D., Aranda, E., O’Neill, J. D. & 3 others, Walker, C., Landesman, Y. & Madak-Erdogan, Z., Aug 22 2020, In : Cancers. 12, 9, 2397.

Research output: Contribution to journalArticle

Open Access
2015

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C. M., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In : Science Translational Medicine. 7, 271, 271ra9.

Research output: Contribution to journalArticle

2017

MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression

Christenson, J. L., Butterfield, K. T., Spoelstra, N. S., Norris, J. D., Josan, J. S., Pollock, J. A., McDonnell, D. P., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Richer, J. K., Apr 1 2017, In : Hormones and Cancer. 8, 2, p. 69-77 9 p.

Research output: Contribution to journalArticle