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• Profiling of Microbial Colonies for High-Throughput Engineering of Multistep Enzymatic Reactions via Optically Guided Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

  Si, T., Li, B., Comi, T. J., Wu, Y., Hu, P., Wu, Y., Min, Y., Mitchell, D. A., Zhao, H. & Sweedler, J. V., Sep 13 2017, In: Journal of the American Chemical Society. 139, 36, p. 12466-12473 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionization
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Desorption
  • ionization

• Profiling metabolites and peptides in single cells

  Rubakhin, S. S., Romanova, E. V., Nemes, P. & Sweedler, J. V., Apr 2011, In: Nature Methods. 8, 4, p. S20-S29

  Research output: Contribution to journal › Article › peer-review

  • Metabolites
  • Developmental Biology
  • Cytology
  • Stem cells
  • Microanalysis

• Probing the production of amidated peptides following genetic and dietary copper manipulations

  Yin, P., Bousquet-Moore, D., Annangudi, S. P., Southey, B. R., Mains, R. E., Eipper, B. A. & Sweedler, J. V., Dec 16 2011, In: PloS one. 6, 12, e28679.

  Research output: Contribution to journal › Article › peer-review

  • peptidylglycine monooxygenase
  • Mixed Function Oxygenases
  • Copper
  • copper
  • peptides

• Pittcon: Still vibrant after more than 60 years

  Sweedler, J. V., Mar 5 2013, In: Analytical chemistry. 85, 5, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Peptidomics for the discovery and characterization of neuropeptides and hormones

  Romanova, E. V. & Sweedler, J. V., Sep 12 2015, In: Trends in Pharmacological Sciences. 36, 9, p. 579-586 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neuropeptides
  • G-Protein-Coupled Receptors
  • Hormones
  • Orphaned Children
  • Mass spectrometry

• Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System

  Tillmaand, E. G., Yang, N., Kindt, C. A. C., Romanova, E. V., Rubakhin, S. S. & Sweedler, J. V., Dec 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 12, p. 2051-2061 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Spinal Ganglia
  • Mass spectrometry
  • Peptides
  • Spinal Nerve Roots
  • Mass Spectrometry

• Peptide identifications and false discovery rates using different mass spectrometry platforms

  Anapindi, K. D. B., Romanova, E. V., Southey, B. R. & Sweedler, J. V., May 15 2018, In: Talanta. 182, p. 456-463 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Peptides
  • Neuropeptides
  • Protein Precursors
  • Bioinformatics

• PACAP and other neuropeptide targets link chronic migraine and opioid-induced hyperalgesia in mouse models

  Anapindi, K. D. B., Yang, N., Romanova, E. V., Rubakhin, S. S., Tipton, A., Dripps, I., Sheets, Z., Sweedler, J. V. & Pradhan, A. A., 2019, In: Molecular and Cellular Proteomics. 18, 12, p. 2447-2458 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Pituitary Adenylate Cyclase-Activating Polypeptide
  • Hyperalgesia
  • Neuropeptides
  • Migraine Disorders
  • Opioid Analgesics

• Our editorial team

  Sweedler, J. V., Jun 2 2015, In: Analytical chemistry. 87, 11, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Optically Guided Single Cell Mass Spectrometry of Rat Dorsal Root Ganglia to Profile Lipids, Peptides and Proteins

  Do, T. D., Ellis, J. F., Neumann, E. K., Comi, T. J., Tillmaand, E. G., Lenhart, A. E., Rubakhin, S. S. & Sweedler, J. V., May 22 2018, In: ChemPhysChem. 19, 10, p. 1180-1191 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Rats
  • peptides
  • rats
  • lipids

• Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens

  Zhang, P., Moye, L. S., Southey, B. R., Dripps, I., Sweedler, J. V., Pradhan, A. & Rodriguez-Zas, S. L., Dec 1 2019, In: Molecular Neurobiology. 56, 12, p. 7929-7949 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Trigeminal Nuclei
  • Trigeminal Ganglion
  • Hyperalgesia
  • Nucleus Accumbens
  • Circadian Rhythm

• Non-targeted identification of d-amino acid-containing peptides through enzymatic screening, chiral amino acid analysis, and LC-MS

  Tai, H. C., Checco, J. W. & Sweedler, J. V., 2018, Methods in Molecular Biology. Humana Press Inc., p. 107-118 12 p. (Methods in Molecular Biology; vol. 1719).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amino Acids
  • Peptides
  • Post Translational Protein Processing
  • Mass Spectrometry
  • Animals

• New Mass Spectrometric Approaches for Uncovering Neuropeptides

  Hou, X. & Sweedler, J. V., Aug 29 2013, Handbook of Biologically Active Peptides. Elsevier Inc., p. 1749-1756 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Newly Identified Aplysia SPTR-Gene Family-Derived Peptides: Localization and Function

  Zhang, G., Yuan, W. D., Vilim, F. S., Romanova, E. V., Yu, K., Yin, S. Y., Le, Z. W., Xue, Y. Y., Chen, T. T., Chen, G. K., Chen, S. A., Cropper, E. C., Sweedler, J. V., Weiss, K. R. & Jing, J., Aug 15 2018, In: ACS Chemical Neuroscience. 9, 8, p. 2041-2053 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Aplysia
  • Interneurons
  • Genes
  • Cheek
  • Peptides

• Neuropeptidomics of the Rat Habenular Nuclei

  Yang, N., Anapindi, K. D. B., Rubakhin, S. S., Wei, P., Yu, Q., Li, L., Kenny, P. J. & Sweedler, J. V., Apr 6 2018, In: Journal of Proteome Research. 17, 4, p. 1463-1473 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Habenula
  • Mass spectrometry
  • Rats
  • Tandem Mass Spectrometry
  • Neuropeptides

• Neuropeptidomics of the mammalian brain

  Xie, F., Romanova, E. V. & Sweedler, J. V., Jun 3 2011, Neuroproteomics. Li, K. W. (ed.). p. 229-242 14 p. (Neuromethods; vol. 57).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Brain
  • Mass spectrometry
  • Peptides
  • Mass Spectrometry
  • Liquid chromatography

• Neuropeptidomics of the mammalian brain

  Xie, F., Anapindi, K. D. B., Romanova, E. V. & Sweedler, J. V., 2019, Neuromethods. Humana Press Inc., p. 161-177 17 p. (Neuromethods; vol. 146).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Brain
  • Mass spectrometry
  • Peptides
  • Mass Spectrometry
  • Liquid chromatography

• Neuropeptidomics: Mass spectrometry-based qualitative and quantitative analysis

  Yin, P., Hou, X., Romanova, E. V. & Sweedler, J. V., 2011, Neuropeptides: Methods and Protocols. Merighi, A. (ed.). p. 223-236 14 p. (Methods in Molecular Biology; vol. 789).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neuropeptides
  • Mass Spectrometry
  • Liquid Chromatography
  • Peptides
  • Protein Precursors

• Neuropeptidomics

  Sweedler, J. V., Xie, F. & Bora, A., Sep 23 2011, Protein and Peptide Mass Spectrometry in Drug Discovery. John Wiley and Sons, p. 393-433 41 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Nanopipet-based liquid-liquid interface probes for the electrochemical detection of acetylcholine, tryptamine, and serotonin via ionic transfer

  Colombo, M. L., Sweedler, J. V. & Shen, M., May 19 2015, In: Analytical Chemistry. 87, 10, p. 5095-5100 6 p.

  Research output: Contribution to journal › Article › peer-review

  • tryptamine
  • Acetylcholine
  • Serotonin
  • Electrodes
  • Liquids

• Multimodal chemical imaging of molecular messengers in emerging Pseudomonas aeruginosa bacterial communities

  Baig, N. F., Dunham, S. J. B., Morales-Soto, N., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 7 2015, In: Analyst. 140, 19, p. 6544-6552 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Multimodal Imaging
  • Biofilms
  • Pseudomonas aeruginosa
  • biofilm
  • Oxides

• Multimodal Chemical Analysis of the Brain by High Mass Resolution Mass Spectrometry and Infrared Spectroscopic Imaging

  Neumann, E. K., Comi, T. J., Spegazzini, N., Mitchell, J. W., Rubakhin, S. S., Gillette, M. U., Bhargava, R. & Sweedler, J. V., Oct 2 2018, In: Analytical Chemistry. 90, 19, p. 11572-11580 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Infrared radiation
  • Brain
  • Imaging techniques
  • Chemical analysis

• Multifactorial understanding of ion abundance in tandem mass spectrometry experiments

  Fazal, Z., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., 2013, In: Journal of Proteomics and Bioinformatics. 6, 2, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Tandem Mass Spectrometry
  • Ions
  • Peptides
  • Experiments

• Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol

  Park, H. M., Satta, R., Davis, R. G., Goo, Y. A., Leduc, R. D., Fellers, R. T., Greer, J. B., Romanova, E. V., Rubakhin, S. S., Tai, R., Thomas, P. M., Sweedler, J. V., Kelleher, N. L., Patrie, S. M. & Lasek, A. W., Nov 1 2019, In: Journal of Proteome Research. 18, 11, p. 3999-4012 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Cocaine
  • Estradiol
  • Brain
  • Estrogens

• Molecular organization of drosophila neuroendocrine cells by dimmed

  Park, D., Hadžić, T., Yin, P., Rusch, J., Abruzzi, K., Rosbash, M., Skeath, J. B., Panda, S., Sweedler, J. V. & Taghert, P. H., Sep 27 2011, In: Current Biology. 21, 18, p. 1515-1524 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroendocrine Cells
  • Drosophila
  • Assays
  • Secretory Vesicles
  • cytochrome b561

• Molecular and Physiological Characterization of a Receptor for d -Amino Acid-Containing Neuropeptides

  Checco, J. W., Zhang, G., Yuan, W. D., Yu, K., Yin, S. Y., Roberts-Galbraith, R. H., Yau, P. M., Romanova, E. V., Jing, J. & Sweedler, J. V., May 18 2018, In: ACS chemical biology. 13, 5, p. 1343-1352 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Receptors
  • Neuropeptides
  • Neuropeptide Receptors
  • Amino Acids
  • Aplysia

• Model of ion intensity from tandem mass spectra for improved peptide identification and simulation

  Fazal, Z., Southey, B. R., Sadeque, A., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 994-996 3 p. 6112534. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Peptides
  • Ions
  • Mass spectrometry
  • Protons
  • Tandem Mass Spectrometry

• Microscale transport physics during atomic force microscopy mass spectrometry and improved sampling efficiency

  Moon, H., Comi, T. J., Dunham, S. J. B., Kwon, B., Sweedler, J. V. & King, W. P., Jul 26 2017, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., p. 24-27 4 p. 7993978. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Mass spectrometry
  • Atomic force microscopy
  • microbalances
  • mass spectroscopy
  • Physics

• microMS: A Python Platform for Image-Guided Mass Spectrometry Profiling

  Comi, T. J., Neumann, E. K., Do, T. D. & Sweedler, J. V., Sep 1 2017, In: Journal of the American Society for Mass Spectrometry. 28, 9, p. 1919-1928 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Boidae
  • Mass spectrometry
  • Mass Spectrometry
  • Microscopic examination
  • Microscopy

• Microfluidic systems for studying neurotransmitters and neurotransmission

  Croushore, C. A. & Sweedler, J. V., May 7 2013, In: Lab on a chip. 13, 9, p. 1666-1676 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Microfluidics
  • Molecules
  • Synaptic Transmission
  • Neurotransmitter Agents
  • Cell signaling

• Microbeam-coupled capillary electrophoresis

  Garty, G., Ehsan, M. U., Buonanno, M., Yang, Z., Sweedler, J. V. & Brenner, D. J., Sep 1 2015, In: Radiation Protection Dosimetry. 166, 1-4, p. 188-191 4 p., ncv148.

  Research output: Contribution to journal › Article › peer-review

  • Capillary Electrophoresis
  • microbeams
  • electrophoresis
  • charged particles
  • Reactive Oxygen Species

• Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord

  Miller, L. K., Hou, X., Rodriguiz, R. M., Gagnidze, K., Sweedler, J. V., Wetsel, W. C. & Devi, L. A., Dec 2011, In: Journal of Neurochemistry. 119, 5, p. 1074-1085 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin-Converting Enzymes
  • Morphine
  • Spinal Cord
  • Peptides
  • Neuropeptides

• Metrics to Evaluate Journals, Scientists, and Science: We Are Not There Yet

  Sweedler, J. V., Jun 6 2017, In: Analytical Chemistry. 89, 11, p. 5653 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry

  Nemes, P., Knolhoff, A. M., Rubakhin, S. S. & Sweedler, J. V., Sep 1 2011, In: Analytical chemistry. 83, 17, p. 6810-6817 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Mass spectrometry
  • Neurons
  • Metabolites

• Meet the Analytical Chemistry editorial advisory board

  Sweedler, J. V., Feb 5 2013, In: Analytical chemistry. 85, 3, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Meet our second advisory board, the analytical chemistry features panel

  Sweedler, J. V., Aug 20 2013, In: Analytical chemistry. 85, 16, 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Mass spectrometry imaging of complex microbial communities

  Dunham, S. J. B., Ellis, J. F., Li, B. & Sweedler, J. V., Jan 17 2017, In: Accounts of chemical research. 50, 1, p. 96-104 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Imaging techniques
  • Metabolomics
  • Microbiology
  • Metabolites

• Mass spectrometry imaging and GC-MS profiling of the mammalian peripheral sensory-motor circuit

  Rubakhin, S. S., Ulanov, A. & Sweedler, J. V., Jun 1 2015, In: Journal of the American Society for Mass Spectrometry. 26, 6, p. 958-966 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Spinal Ganglia
  • Mass Spectrometry
  • Imaging techniques
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

• Mass spectrometry-based characterization of endogenous peptides and metabolites in small volume samples

  Ong, T. H., Tillmaand, E. G., Makurath, M., Rubakhin, S. S. & Sweedler, J. V., Jul 1 2015, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1854, 7, p. 732-740 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Metabolites
  • Mass spectrometry
  • Mass Spectrometry
  • Peptides
  • Assays

• MALDI MS Guided Liquid Microjunction Extraction for Capillary Electrophoresis-Electrospray Ionization MS Analysis of Single Pancreatic Islet Cells

  Comi, T. J., Makurath, M. A., Philip, M. C., Rubakhin, S. S. & Sweedler, J. V., Jul 18 2017, In: Analytical Chemistry. 89, 14, p. 7765-7772 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Electrospray ionization
  • Capillary electrophoresis
  • Ionization
  • Mass spectrometry
  • Desorption

• MALDI mass spectrometry imaging of neuronal cell cultures

  Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 2011, In: Journal of the American Society for Mass Spectrometry. 22, 5, p. 828-836 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell culture
  • Mass spectrometry
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
  • Aplysia
  • Mass Spectrometry

• Making the Editor's Job Easier: Let Us Know about Prior Submissions and Related Manuscripts

  Sweedler, J. V., Apr 18 2017, In: Analytical Chemistry. 89, 8, p. 4329 1 p.

  Research output: Contribution to journal › Editorial › peer-review

• Lipid Heterogeneity between Astrocytes and Neurons Revealed by Single-Cell MALDI-MS Combined with Immunocytochemical Classification

  Neumann, E. K., Comi, T. J., Rubakhin, S. S. & Sweedler, J. V., Apr 23 2019, In: Angewandte Chemie - International Edition. 58, 18, p. 5910-5914 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Astrocytes
  • Lipids
  • Ionization
  • Mass spectrometry
  • Desorption

• Lipid Analysis of 30 000 Individual Rodent Cerebellar Cells Using High-Resolution Mass Spectrometry

  Neumann, E. K., Ellis, J. F., Triplett, A. E., Rubakhin, S. S. & Sweedler, J. V., Jan 1 2019, In: Analytical Chemistry.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Lipids
  • Cyclotron resonance
  • Ionization
  • Rats

• Laminar stream of detergents for subcellular neurite damage in a microfluidic device: A simple tool for the study of neuroregeneration

  Lee, C. Y., Romanova, E. V. & Sweedler, J. V., Jun 2013, In: Journal of Neural Engineering. 10, 3, 036020.

  Research output: Contribution to journal › Article › peer-review

  • Lab-On-A-Chip Devices
  • Detergents
  • Neurites
  • Microfluidics
  • Neurons

• Is the Power List a Representative List?

  Sweedler, J. V., Dec 3 2019, In: Analytical Chemistry. 91, 23, p. 14783 1 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Investigating brain d-serine: Advocacy for good practices

  Mothet, J. P., Billard, J. M., Pollegioni, L., Coyle, J. T. & Sweedler, J. V., May 2019, In: Acta Physiologica. 226, 1, e13257.

  Research output: Contribution to journal › Review article › peer-review

  • Amino Acids
  • Brain
  • Molecular Models
  • Practice Guidelines
  • Nervous System

• Interrogation of spatial metabolome of Ginkgo biloba with high-resolution matrix-assisted laser desorption/ionization and laser desorption/ionization mass spectrometry imaging

  Li, B., Neumann, E. K., Ge, J., Gao, W., Yang, H., Li, P. & Sweedler, J. V., Nov 2018, In: Plant Cell and Environment. 41, 11, p. 2693-2703 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ginkgo
  • Ginkgo biloba
  • metabolome
  • Metabolome
  • ionization

• Integration of untargeted metabolomics with transcriptomics reveals active metabolic pathways

  Cho, K., Evans, B. S., Wood, B. M. K., Kumar, R., Erb, T. J., Warlick, B. P., Gerlt, J. A. & Sweedler, J. V., Jun 1 2015, In: Metabolomics. 11, 3, p. 503-517 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolic Networks and Pathways
  • Salvaging
  • Methionine
  • Metabolites

• Integration of sequence and functional information to identify and annotate neuropeptides in the pig genome

  Porter, K. I., Southey, B. R., Akhtar, M. N., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 988-990 3 p. 6112532. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Neuropeptides
  • Genes
  • Swine
  • Genome
  • proenkephalin