Find Research Outputs

Search in all content

Filters for Research & Scholarship

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Yi Lu
2016

A density functional theory protocol for the calculation of redox potentials of copper complexes

Yan, L., Lu, Y. & Li, X., Jan 1 2016, In : Physical Chemistry Chemical Physics. 18, 7, p. 5529-5536 8 p.

Research output: Contribution to journalArticle

A Highly Efficient Single-Chain Metal-Organic Nanoparticle Catalyst for Alkyne-Azide "click" Reactions in Water and in Cells

Bai, Y., Feng, X., Xing, H., Xu, Y., Kim, B. K., Baig, N., Zhou, T., Gewirth, A. A., Lu, Y., Oldfield, E. & Zimmerman, S. C., Sep 7 2016, In : Journal of the American Chemical Society. 138, 35, p. 11077-11080 4 p.

Research output: Contribution to journalArticle

A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site

Hosseinzadeh, P., Tian, S., Marshall, N. M., Hemp, J., Mullen, T., Nilges, M. J., Gao, Y. G., Robinson, H., Stahl, D. A., Gennis, R. B. & Lu, Y., May 25 2016, In : Journal of the American Chemical Society. 138, 20, p. 6324-6327 4 p.

Research output: Contribution to journalArticle

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

Hwang, K., Hosseinzadeh, P. & Lu, Y., 2016, In : Inorganica Chimica Acta. 452, p. 12-24 13 p.

Research output: Contribution to journalReview article

Design and engineering of artificial oxygen-activating metalloenzymes

Nastri, F., Chino, M., Maglio, O., Bhagi-Damodaran, A., Lu, Y. & Lombardi, A., Sep 21 2016, In : Chemical Society Reviews. 45, 18, p. 5020-5054 35 p.

Research output: Contribution to journalReview article

Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics

Hosseinzadeh, P. & Lu, Y., May 1 2016, In : Biochimica et Biophysica Acta - Bioenergetics. 1857, 5, p. 557-581 25 p.

Research output: Contribution to journalArticle

Design of a single protein that spans the entire 2-V range of physiological redox potentials

Hosseinzadeh, P., Marshall, N. M., Chacón, K. N., Yu, Y., Nilges, M. J., New, S. Y., Tashkov, S. A., Blackburn, N. J. & Lu, Y., Jan 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 2, p. 262-267 6 p.

Research output: Contribution to journalArticle

Design of Heteronuclear Metalloenzymes

Bhagi-Damodaran, A., Hosseinzadeh, P., Mirts, E., Reed, J., Petrik, I. D. & Lu, Y., Jan 1 2016, Methods in Enzymology. Academic Press Inc., p. 501-537 37 p. (Methods in Enzymology; vol. 580).

Research output: Chapter in Book/Report/Conference proceedingChapter

DNA-Mediated Morphological Control of Pd-Au Bimetallic Nanoparticles

Satyavolu, N. S. R., Tan, L. H. & Lu, Y., Dec 21 2016, In : Journal of the American Chemical Society. 138, 50, p. 16542-16548 7 p.

Research output: Contribution to journalArticle

Effect of Outer-Sphere Side Chain Substitutions on the Fate of the trans Iron-Nitrosyl Dimer in Heme/Nonheme Engineered Myoglobins (FeBMbs): Insights into the Mechanism of Denitrifying NO Reductases

Matsumura, H., Chakraborty, S., Reed, J., Lu, Y. & Moënne-Loccoz, P., Apr 12 2016, In : Biochemistry. 55, 14, p. 2091-2099 9 p.

Research output: Contribution to journalArticle

Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions

Hosseinzadeh, P., Mirts, E. N., Pfister, T. D., Gao, Y. G., Mayne, C., Robinson, H., Tajkhorshid, E. & Lu, Y., Mar 15 2016, In : Biochemistry. 55, 10, p. 1494-1502 9 p.

Research output: Contribution to journalArticle

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

Zhang, J. J., Cheng, F. F., Li, J. J., Zhu, J. J. & Lu, Y., Jun 1 2016, In : Nano Today. 11, 3, p. 309-329 21 p.

Research output: Contribution to journalReview article

Integration of Solution-Based Assays onto Lateral Flow Device for One-Step Quantitative Point-of-Care Diagnostics Using Personal Glucose Meter

Zhang, J., Shen, Z., Xiang, Y. & Lu, Y., Sep 23 2016, In : ACS Sensors. 1, 9, p. 1091-1096 6 p.

Research output: Contribution to journalArticle

Multimodal Detection of a Small Molecule Target Using Stimuli-Responsive Liposome Triggered by Aptamer-Enzyme Conjugate

Xing, H., Zhang, C. L., Ruan, G., Zhang, J., Hwang, K. & Lu, Y., Feb 2 2016, In : Analytical chemistry. 88, 3, p. 1506-1510 5 p.

Research output: Contribution to journalArticle

Recent developments of liposomes as nanocarriers for theranostic applications

Xing, H., Hwang, K. & Lu, Y., Jan 1 2016, In : Theranostics. 6, 9, p. 1336-1352 17 p.

Research output: Contribution to journalReview article

Reversible S-nitrosylation in an engineered azurin

Tian, S., Liu, J., Cowley, R. E., Hosseinzadeh, P., Marshall, N. M., Yu, Y., Robinson, H., Nilges, M. J., Blackburn, N. J., Solomon, E. I. & Lu, Y., Jul 1 2016, In : Nature Chemistry. 8, 7, p. 670-677 8 p.

Research output: Contribution to journalArticle

Size-dependent modulation of graphene oxide-aptamer interactions for an amplified fluorescence-based detection of aflatoxin B1 with a tunable dynamic range

Zhang, J., Li, Z., Zhao, S. & Lu, Y., Jul 7 2016, In : Analyst. 141, 13, p. 4029-4034 6 p.

Research output: Contribution to journalArticle

Spectroscopic and Crystallographic Evidence for the Role of a Water-Containing H-Bond Network in Oxidase Activity of an Engineered Myoglobin

Petrik, I. D., Davydov, R., Ross, M., Zhao, X., Hoffman, B. & Lu, Y., Feb 3 2016, In : Journal of the American Chemical Society. 138, 4, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase

Chauhan, S., Hosseinzadeh, P., Lu, Y. & Blackburn, N. J., Apr 19 2016, In : Biochemistry. 55, 13, p. 2008-2021 14 p.

Research output: Contribution to journalArticle

The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin

Xing, H., Li, J., Xu, W., Hwang, K., Wu, P., Yin, Q., Li, Z., Cheng, J. & Lu, Y., Jun 16 2016, In : ChemBioChem. p. 1111-1117 7 p.

Research output: Contribution to journalArticle

Transforming the blood glucose meter into a general healthcare meter for in vitro diagnostics in mobile health

Lan, T., Zhang, J. & Lu, Y., May 1 2016, In : Biotechnology Advances. 34, 3, p. 331-341 11 p.

Research output: Contribution to journalReview article

Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities

Bhagi-Damodaran, A., Petrik, I. & Lu, Y., Oct 1 2016, In : Israel Journal of Chemistry. 56, 9-10, p. 773-790 18 p.

Research output: Contribution to journalReview article

2017

Advances in the development of aptamer drug conjugates for targeted drug delivery

Chen, K., Liu, B., Yu, B., Zhong, W., Lu, Y., Zhang, J., Liao, J., Liu, J., Pu, Y., Qiu, L., Zhang, L., Liu, H. & Tan, W., May 1 2017, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 9, 3, e1438.

Research output: Contribution to journalReview article

Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids

Yu, Y., Cui, C., Wang, J. & Lu, Y., Feb 1 2017, In : Science China Chemistry. 60, 2, p. 188-200 13 p.

Research output: Contribution to journalReview article

Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand

Xing, H., Bai, Y., Bai, Y., Tan, L. H., Tao, J., Pedretti, B., Vincil, G. A., Lu, Y. & Zimmerman, S. C., Mar 15 2017, In : Journal of the American Chemical Society. 139, 10, p. 3623-3626 4 p.

Research output: Contribution to journalArticle

DNA Aptamer-Based Activatable Probes for Photoacoustic Imaging in Living Mice

Zhang, J., Smaga, L. P., Satyavolu, N. S. R., Chan, J. & Lu, Y., Dec 6 2017, In : Journal of the American Chemical Society. 139, 48, p. 17225-17228 4 p.

Research output: Contribution to journalArticle

DNAzyme sensors for detection of metal ions in the environment and imaging them in living cells

McGhee, C. E., Loh, K. Y. & Lu, Y., Jun 1 2017, In : Current Opinion in Biotechnology. 45, p. 191-201 11 p.

Research output: Contribution to journalReview article

Effect of circular permutation on the structure and function of type 1 blue copper center in azurin

Yu, Y., Petrik, I. D., Chacón, K. N., Hosseinzadeh, P., Chen, H., Blackburn, N. J. & Lu, Y., Feb 1 2017, In : Protein Science. 26, 2, p. 218-226 9 p.

Research output: Contribution to journalArticle

Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme–Catalytic Hairpin Assembly Probe

Wu, Z., Fan, H., Satyavolu, N. S. R., Wang, W. J., Lake, R., Jiang, J. H. & Lu, Y., Jul 17 2017, In : Angewandte Chemie - International Edition. 56, 30, p. 8721-8725 5 p.

Research output: Contribution to journalArticle

Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase

Bhagi-Damodaran, A., Kahle, M., Shi, Y., Zhang, Y., Ädelroth, P. & Lu, Y., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 23, p. 6622-6626 5 p.

Research output: Contribution to journalArticle

Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism

Reed, J. H., Shi, Y., Zhu, Q., Chakraborty, S., Mirts, E. N., Petrik, I. D., Bhagi-Damodaran, A., Ross, M., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Sep 6 2017, In : Journal of the American Chemical Society. 139, 35, p. 12209-12218 10 p.

Research output: Contribution to journalArticle

Near-Infrared Photothermally Activated DNAzyme–Gold Nanoshells for Imaging Metal Ions in Living Cells

Wang, W., Satyavolu, N. S. R., Wu, Z., Zhang, J. R., Zhu, J. J. & Lu, Y., Jan 1 2017, In : Angewandte Chemie - International Edition. 56, 24, p. 6798-6802 5 p.

Research output: Contribution to journalArticle

Recent advances in DNAzyme-based gene silencing

Fan, H., Zhang, X. & Lu, Y., May 1 2017, In : Science China Chemistry. 60, 5, p. 591-601 11 p.

Research output: Contribution to journalReview article

The "ok, molly" chemistry

Lu, Y., Jan 1 2017, In : Accounts of chemical research. 50, 3, p. 647-651 5 p.

Research output: Contribution to journalReview article

Thiolate Spin Population of Type I Copper in Azurin Derived from33S Hyperfine Coupling

Ramirez Cohen, M., Mendelman, N., Radoul, M., Wilson, T. D., Savelieff, M. G., Zimmermann, H., Kaminker, I., Feintuch, A., Lu, Y. & Goldfarb, D., Jun 5 2017, In : Inorganic Chemistry. 56, 11, p. 6163-6174 12 p.

Research output: Contribution to journalArticle

Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases

Bhagi-Damodaran, A., Michael, M. A., Zhu, Q., Reed, J., Sandoval, B. A., Mirts, E. N., Chakraborty, S., Moënne-Loccoz, P., Zhang, Y. & Lu, Y., Mar 1 2017, In : Nature Chemistry. 9, 3, p. 257-263 7 p.

Research output: Contribution to journalArticle

“Dipstick” colorimetric detection of metal ions based on immobilization of DNAzyme and gold nanoparticles onto a lateral flow device

Mazumdar, D., Lan, T. & Lu, Y., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 389-406 18 p. (Methods in Molecular Biology; vol. 1571).

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme

Mirts, E. N., Petrik, I. D., Hosseinzadeh, P., Nilges, M. J. & Lu, Y., Sep 14 2018, In : Science. 361, 6407, p. 1098-1101 4 p.

Research output: Contribution to journalArticle

A new era for electron bifurcation

Peters, J. W., Beratan, D. N., Bothner, B., Dyer, R. B., Harwood, C. S., Heiden, Z. M., Hille, R., Jones, A. K., King, P. W., Lu, Y., Lubner, C. E., Minteer, S. D., Mulder, D. W., Raugei, S., Schut, G. J., Seefeldt, L. C., Tokmina-Lukaszewska, M., Zadvornyy, O. A., Zhang, P. & Adams, M. WW., Dec 2018, In : Current Opinion in Chemical Biology. 47, p. 32-38 7 p.

Research output: Contribution to journalReview article

DNA-encoded morphological evolution of bimetallic Pd@Au core-shell nanoparticles from a high-indexed core

Satyavolu, N. S. R., Pishevaresfahani, N., Tan, L. H. & Lu, Y., Sep 1 2018, In : Nano Research. 11, 9, p. 4549-4561 13 p.

Research output: Contribution to journalArticle

Evidence of a General Acid-Base Catalysis Mechanism in the 8-17 DNAzyme

Cepeda-Plaza, M., McGhee, C. E. & Lu, Y., Mar 6 2018, In : Biochemistry. 57, 9, p. 1517-1522 6 p.

Research output: Contribution to journalArticle

Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase

Bhagi-Damodaran, A., Reed, J. H., Zhu, Q., Shi, Y., Hosseinzadeh, P., Sandoval, B. A., Harnden, K. A., Wang, S., Sponholtz, M. R., Mirts, E. N., Dwaraknath, S., Zhang, Y., Moënne-Loccoz, P. & Lu, Y., Jun 12 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 24, p. 6195-6200 6 p.

Research output: Contribution to journalArticle

Insights into the Competition between K+ and Pb2+ Binding to a G-Quadruplex and Discovery of a Novel K+-Pb2+-Quadruplex Intermediate

Yu, Z., Zhou, W., Ma, G., Li, Y., Fan, L., Li, X. & Lu, Y., Oct 11 2018, In : Journal of Physical Chemistry B. 122, 40, p. 9382-9388 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Reductase Activity in Heme-Nonheme Binuclear Engineered Myoglobins through a One-Electron Reduction Cycle

Sabuncu, S., Reed, J. H., Lu, Y. & Moënne-Loccoz, P., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17389-17393 5 p.

Research output: Contribution to journalArticle

O2 Reduction by Biosynthetic Models of Cytochrome c Oxidase: Insights into Role of Proton Transfer Residues from Perturbed Active Sites Models of CcO

Mukherjee, S., Mukherjee, M., Mukherjee, A., Bhagi-Damodaran, A., Lu, Y. & Dey, A., Sep 7 2018, In : ACS Catalysis. 8, 9, p. 8915-8924 10 p.

Research output: Contribution to journalArticle

Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles

Yang, Z., Loh, K. Y., Chu, Y. T., Feng, R., Satyavolu, N. S. R., Xiong, M., Nakamata Huynh, S. M., Hwang, K., Li, L., Xing, H., Zhang, X., Chemla, Y. R., Gruebele, M. & Lu, Y., Dec 19 2018, In : Journal of the American Chemical Society. 140, 50, p. 17656-17665 10 p.

Research output: Contribution to journalArticle

Sequence-specific control of inorganic nanomaterials morphologies by biomolecules

Wang, Y., Reddy Satyavolu, N. S. & Lu, Y., Nov 2018, In : Current Opinion in Colloid and Interface Science. 38, p. 158-169 12 p.

Research output: Contribution to journalReview article