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  • Benita S Katzenellenbogen
2011

Estrogen receptor β ligands: Recent advances and biomedical applications

Minutolo, F., Macchia, M., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., May 2011, In : Medicinal Research Reviews. 31, 3, p. 364-442 79 p.

Research output: Contribution to journalArticle

Estrogen-regulated prohibitin is required for mouse uterine development and adult function

He, B., Kim, T. H., Kommagani, R., Feng, Q., Lanz, R. B., Jeong, J. W., DeMayo, F. J., Katzenellenbogen, B. S., Lydon, J. P. & O'Malley, B. W., Mar 2011, In : Endocrinology. 152, 3, p. 1047-1056 10 p.

Research output: Contribution to journalArticle

Repressor of Estrogen Receptor Activity (REA) is essential for mammary gland morphogenesis and functional activities: Studies in conditional knockout mice

Park, S., Zhao, Y., Yoon, S., Xu, J., Liao, L., Lydon, J., DeMayo, F., O'Malley, B. W. & Katzenellenbogen, B. S., Nov 2011, In : Endocrinology. 152, 11, p. 4336-4349 14 p.

Research output: Contribution to journalArticle

Reversal of endocrine resistance in breast cancer: Interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

Bergamaschi, A., Christensen, B. L. & Katzenellenbogen, B. S., Jun 29 2011, In : Breast Cancer Research. 13, 3, R70.

Research output: Contribution to journalArticle

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In : Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

2012

Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In : Oncogene. 31, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA

Park, S., Yoon, S., Zhao, Y., Park, S. E., Liao, L., Xu, J., Lydon, J. P., DeMayo, F. J., O'Malley, B. W., Bagchi, M. K. & Katzenellenbogen, B. S., Aug 1 2012, In : Endocrinology. 153, 8, p. 3982-3994 13 p.

Research output: Contribution to journalArticle

2013

14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers

Bergamaschi, A., Frasor, J., Borgen, K., Stanculescu, A., Johnson, P., Rowland, K., Wiley, E. L. & Katzenellenbogen, B. S., Feb 1 2013, In : Breast Cancer Research and Treatment. 137, 3, p. 689-696 8 p.

Research output: Contribution to journalArticle

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

Madak-Erdogan, Z., Charn, T. H., Jiang, Y., Liu, E. T., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., 2013, In : Molecular Systems Biology. 9, 201328.

Research output: Contribution to journalArticle

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

Jiang, Y., Gong, P., Madak-Erdogan, Z., Martin, T., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T. J., Chittiboyina, A. G., Rotte, S. C. K., Helferich, W. G., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Nov 2013, In : FASEB Journal. 27, 11, p. 4406-4418 13 p.

Research output: Contribution to journalArticle

Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass

Bartell, S. M., Han, L., Kim, H. N., Kim, S. H., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Chambliss, K. L., Shaul, P. W., Roberson, P. K., Weinstein, R. S., Jilka, R. L., Almeida, M. & Manolagas, S. C., Apr 1 2013, In : Molecular Endocrinology. 27, 4, p. 649-656 8 p.

Research output: Contribution to journalArticle

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In : Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journalArticle

2014

Endocrine Society 2014 Laureate Awards

Gustafsson, J. A., Katzenellenbogen, B., Jameson, J. L., Roth, J., Melmed, S., McDonnell, D., Wartofsky, L., Crowley, W. F., Griz, L. H. E., Becker, C., Moore, D. D., Drucker, D., Singh, N. & O'Malley, B., Oct 1 2014, In : Hormones & cancer. 5, 5, p. 339-355 17 p.

Research output: Contribution to journalArticle

Estrogen-induced CCN1 Is critical for establishment of endometriosis-like lesions in mice

Zhao, Y., Li, Q., Katzenellenbogen, B. S., Lau, L. F., Taylor, R. N., Bagchi, I. C. & Bagchi, M. K., 2014, In : Molecular Endocrinology. 28, 12, p. 1934-1947 14 p.

Research output: Contribution to journalArticle

Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells

Clark, S., Rainville, J., Zhao, X., Katzenellenbogen, B. S., Pfaff, D. & Vasudevan, N., Jan 1 2014, In : Journal of Steroid Biochemistry and Molecular Biology. 139, p. 45-53 9 p.

Research output: Contribution to journalArticle

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Jan 1 2014, In : In Vitro Cellular and Developmental Biology - Animal. 51, 1, p. 59-71 13 p.

Research output: Contribution to journalArticle

Highly sensitive quantitative imaging for monitoring single cancer cell growth kinetics and drug response

Mir, M., Bergamaschi, A., Katzenellenbogen, B. S. & Popescu, G., Feb 18 2014, In : PloS one. 9, 2, e89000.

Research output: Contribution to journalArticle

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valéra, M. C., Gompel, A., Gerard, C., Péqueux, C., Mestdagt, M., Raymond-Letron, I., Knauf, C. & 9 others, Ferriere, F., Valet, P., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Lenfant, F., Greene, G. L., Foidart, J. M. & Arnal, J. F., Oct 1 2014, In : EMBO Molecular Medicine. 6, 10, p. 1328-1346 19 p.

Research output: Contribution to journalArticle

2015

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C. M., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In : Science Translational Medicine. 7, 271, 271ra9.

Research output: Contribution to journalArticle

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

Paterni, I., Bertini, S., Granchi, C., Tuccinardi, T., Macchia, M., Martinelli, A., Caligiuri, I., Toffoli, G., Rizzolio, F., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Minutolo, F., Feb 12 2015, In : Journal of Medicinal Chemistry. 58, 3, p. 1184-1194 11 p.

Research output: Contribution to journalArticle

Ligand accessibility and bioactivity of a hormone-dendrimer conjugate depend on pH and pH history

Kim, S. H., Madak-Erdogan, Z., Bae, S. C., Carlson, K. E., Mayne, C. G., Granick, S., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Aug 19 2015, In : Journal of the American Chemical Society. 137, 32, p. 10326-10335 10 p.

Research output: Contribution to journalArticle

Protective hematopoietic effect of estrogens in a mouse model of thrombosis: Respective roles of nuclear versus membrane estrogen receptor α

Valera, M. C., Fontaine, C., Lenfant, F., Cabou, C., Guillaume, M., Smirnova, N., Kim, S. H., Chambon, P., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Payrastre, B. & Arnal, J. F., Nov 2015, In : Endocrinology. 156, 11, p. 4293-4301 9 p.

Research output: Contribution to journalArticle

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In : Nature communications. 6, 8303.

Research output: Contribution to journalArticle

The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In : Circulation Research. 117, 9, p. 770-777 8 p.

Research output: Contribution to journalArticle

2017

Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells

Min, J., Guillen, V. S., Sharma, A., Zhao, Y., Ziegler, Y., Gong, P., Mayne, C. G., Srinivasan, S., Kim, S. H., Carlson, K. E., Nettles, K. W., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Jul 27 2017, In : Journal of Medicinal Chemistry. 60, 14, p. 6321-6336 16 p.

Research output: Contribution to journalArticle

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

Nelson, A. W., Groen, A. J., Miller, J. L., Warren, A. Y., Holmes, K. A., Tarulli, G. A., Tilley, W. D., Katzenellenbogen, B. S., Hawse, J. R., Gnanapragasam, V. J. & Carroll, J. S., Jan 15 2017, In : Molecular and Cellular Endocrinology. 440, p. 138-150 13 p.

Research output: Contribution to journalArticle

Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms

Martin, A., Yu, J., Xiong, J., Khalid, A. B., Katzenellenbogen, B., Kim, S. H., Katzenellenbogen, J. A., Malaivijitnond, S., Gabet, Y., Krum, S. A. & Frenkel, B., Dec 2017, In : Journal of Cellular Physiology. 232, 12, p. 3798-3807 10 p.

Research output: Contribution to journalArticle

Full antagonism of the estrogen receptor without a prototypical ligand side chain

Srinivasan, S., Nwachukwu, J. C., Bruno, N. E., Dharmarajan, V., Goswami, D., Kastrati, I., Novick, S., Nowak, J., Cavett, V., Zhou, H. B., Boonmuen, N., Zhao, Y., Min, J., Frasor, J., Katzenellenbogen, B. S., Griffin, P. R., Katzenellenbogen, J. A. & Nettles, K. W., Jan 1 2017, In : Nature chemical biology. 13, 1, p. 111-118 8 p.

Research output: Contribution to journalArticle

Membrane and nuclear estrogen receptor alpha actions: From tissue specificity to medical implications

Arnal, J. F., Lenfant, F., Metivier, R., Flouriot, G., Henrion, D., Adlanmerini, M., Fontaine, C., Gourdy, P., Chambon, P., Katzenellenbogen, B. & Katzenellenbogen, J., Jul 2017, In : Physiological Reviews. 97, 3, p. 1045-1087 43 p.

Research output: Contribution to journalReview article

MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression

Christenson, J. L., Butterfield, K. T., Spoelstra, N. S., Norris, J. D., Josan, J. S., Pollock, J. A., McDonnell, D. P., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Richer, J. K., Apr 1 2017, In : Hormones and Cancer. 8, 2, p. 69-77 9 p.

Research output: Contribution to journalArticle

Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice

Menazza, S., Sun, J., Appachi, S., Chambliss, K. L., Kim, S. H., Aponte, A., Khan, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Shaul, P. W. & Murphy, E., Jun 1 2017, In : Journal of Molecular and Cellular Cardiology. 107, p. 41-51 11 p.

Research output: Contribution to journalArticle

Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors

Zhao, Y., Laws, M. J., Guillen, V. S., Ziegler, Y., Min, J., Sharma, A., Kim, S. H., Chu, D., Park, B. H., Oesterreich, S., Mao, C., Shapiro, D. J., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5602-5613 12 p.

Research output: Contribution to journalArticle

2019

Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In : npj Breast Cancer. 5, 1, 45.

Research output: Contribution to journalArticle

Open Access