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2011

A diverse family of novel peptide toxins from an unusual cone snail, Conus californicus

Gilly, W. F., Richmond, T. A., Duda, T. F., Elliger, C., Lebaric, Z., Schulz, J., Bingham, J. P. & Sweedler, J. V., Jan 1 2011, In : Journal of Experimental Biology. 214, 1, p. 147-161 15 p.

Research output: Contribution to journalArticle

Conus Snail
seed cones
peptide
snail
toxin

A novel pyridoxal 5'-phosphate-dependent amino acid racemase in the aplysia californica central nervous system

Wang, L., Ota, N., Romanova, E. V. & Sweedler, J. V., Apr 15 2011, In : Journal of Biological Chemistry. 286, 15, p. 13765-13774 10 p.

Research output: Contribution to journalArticle

aspartate racemase
Amino Acid Isomerases
D-Aspartic Acid
Aplysia
Pyridoxal Phosphate

Chronic morphine alters the presynaptic protein profile: Identification of novel molecular targets using proteomics and network analysis

Abul-Husn, N. S., Annangudi, S. P., Ma'ayan, A., Ramos-Ortolaza, D. L., Stockton, S. D., Gomes, I., Sweedler, J. V. & Devi, L. A., Oct 17 2011, In : PloS one. 6, 10, e25535.

Research output: Contribution to journalArticle

morphine
Electric network analysis
Proteomics
proteomics
Morphine
ethylenediamine
Neurons
Ionization
Mass spectrometry
Pyrrolidinones

Comparison of tandem mass spectrometry search methods to identify neuropeptides

Akhtar, M. N., Southey, B. R., Porter, K. I., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 982-984 3 p. 6112530. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tandem Mass Spectrometry
Neuropeptides
Mass spectrometry
Peptides
Amino acids

Direct cellular peptidomics of hypothalamic neurons

Mitchell, J. W., Atkins, N., Sweedler, J. V. & Gillette, M. L., Oct 1 2011, In : Frontiers in Neuroendocrinology. 32, 4, p. 377-386 10 p.

Research output: Contribution to journalReview article

Neurons
Peptides
Cell signaling
Supraoptic Nucleus
Suprachiasmatic Nucleus
Neuropeptides
Neurons
Mass spectrometry
Amino Acids
Peptides

Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history

Elliger, C. A., Richmond, T. A., Lebaric, Z. N., Pierce, N. T., Sweedler, J. V. & Gilly, W. F., Feb 1 2011, In : Toxicon. 57, 2, p. 311-322 12 p.

Research output: Contribution to journalArticle

Conotoxins
History
Peptides
Complementary DNA
Molluscs

Integration of sequence and functional information to identify and annotate neuropeptides in the pig genome

Porter, K. I., Southey, B. R., Akhtar, M. N., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 988-990 3 p. 6112532. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neuropeptides
Swine
Genes
Genome
Proprotein Convertases

MALDI mass spectrometry imaging of neuronal cell cultures

Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 1 2011, In : Journal of the American Society for Mass Spectrometry. 22, 5, p. 828-836 9 p.

Research output: Contribution to journalArticle

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Cell culture
Mass spectrometry
Aplysia
Mass Spectrometry

Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry

Nemes, P., Knolhoff, A. M., Rubakhin, S. & Sweedler, J. V., Sep 1 2011, In : Analytical chemistry. 83, 17, p. 6810-6817 8 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Electrospray ionization
Neurons
Mass spectrometry
Neurology

Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord

Miller, L. K., Hou, X., Rodriguiz, R. M., Gagnidze, K., Sweedler, J. V., Wetsel, W. C. & Devi, L. A., Dec 1 2011, In : Journal of Neurochemistry. 119, 5, p. 1074-1085 12 p.

Research output: Contribution to journalArticle

Endothelins
Morphine
Spinal Cord
Peptides
Enzymes

Model of ion intensity from tandem mass spectra for improved peptide identification and simulation

Fazal, Z., Southey, B. R., Sadeque, A., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 1 2011, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. p. 994-996 3 p. 6112534. (2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Peptides
Ions
Mass spectrometry
Tandem Mass Spectrometry
Protons

Molecular organization of drosophila neuroendocrine cells by dimmed

Park, D., Hadžić, T., Yin, P., Rusch, J., Abruzzi, K., Rosbash, M., Skeath, J. B., Panda, S., Sweedler, J. V. & Taghert, P. H., Sep 27 2011, In : Current Biology. 21, 18, p. 1515-1524 10 p.

Research output: Contribution to journalArticle

Neuroendocrine Cells
Drosophila
Secretory Vesicles
Assays
Proteins

Neuropeptidomics: Mass spectrometry-based qualitative and quantitative analysis

Yin, P., Hou, X., Romanova, E. V. & Sweedler, J. V., Oct 24 2011, Neuropeptides: Methods and Protocols. Merighi, A. (ed.). p. 223-236 14 p. (Methods in Molecular Biology; vol. 789).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuropeptides
Mass Spectrometry
Liquid Chromatography
Peptides
Protein Precursors

Neuropeptidomics

Sweedler, J. V., Xie, F. & Bora, A., Sep 23 2011, Protein and Peptide Mass Spectrometry in Drug Discovery. John Wiley and Sons, p. 393-433 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuropeptidomics of the mammalian brain

Xie, F., Romanova, E. V. & Sweedler, J. V., Jun 3 2011, Neuroproteomics. Li, K. W. (ed.). p. 229-242 14 p. (Neuromethods; vol. 57).

Research output: Chapter in Book/Report/Conference proceedingChapter

Brain
Peptides
Mass spectrometry
Mass Spectrometry
Liquid chromatography

Probing the production of amidated peptides following genetic and dietary copper manipulations

Yin, P., Bousquet-Moore, D., Annangudi, S. P., Southey, B. R., Mains, R. E., Eipper, B. A. & Sweedler, J. V., Dec 16 2011, In : PloS one. 6, 12, e28679.

Research output: Contribution to journalArticle

Mixed Function Oxygenases
Copper
copper
peptides
Peptides

Profiling metabolites and peptides in single cells

Rubakhin, S. S., Romanova, E. V., Nemes, P. & Sweedler, J. V., Apr 2011, In : Nature Methods. 8, 4, p. S20-S29

Research output: Contribution to journalArticle

Metabolites
Cytology
Peptides
Stem cells
Chemical analysis

Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry

Amaya, K. R., Sweedler, J. V. & Clayton, D. F., Aug 1 2011, In : Journal of Neurochemistry. 118, 4, p. 499-511 13 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Finches
Equidae
Music
Secondary ion mass spectrometry

Stretched tissue mounting for MALDI mass spectrometry imaging

Tucker, K. R., Lanni, E. J., Serebryannyy, L. A., Rubakhin, S. & Sweedler, J. V., Dec 1 2011, In : Analytical chemistry. 83, 23, p. 9181-9185 5 p.

Research output: Contribution to journalArticle

Mountings
Ionization
Mass spectrometry
Desorption
Tissue

The enzyme function initiative

Gerlt, J. A., Allen, K. N., Almo, S. C., Armstrong, R. N., Babbitt, P. C., Cronan, J. E., Dunaway-Mariano, D., Imker, H. J., Jacobson, M. P., Minor, W., Poulter, C. D., Raushel, F. M., Sali, A., Shoichet, B. K. & Sweedler, J. V., Nov 22 2011, In : Biochemistry. 50, 46, p. 9950-9962 13 p.

Research output: Contribution to journalReview article

Enzymes
Microbiology
Genes
Amidohydrolases
Genome

The mechanical sensitivity of vesicle dynamics in in vivo and in vitro neurons

Ahmed, W. W., Li, T. C., Rubakhin, S., Chiba, A., Sweedler, J. V. & Saif, M. T. A., Nov 23 2011, Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011. p. 436-439 4 p. (Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neurons
Cones
Imaging techniques
Compaction

The modified-bead stretched sample method: Development and application to MALDI-MS imaging of protein localization in the spinal cord

Tucker, K. R., Serebryannyy, L. A., Zimmerman, T. A., Rubakhin, S. S. & Sweedler, J. V., May 9 2011, In : Chemical Science. 2, 4, p. 785-795 11 p.

Research output: Contribution to journalArticle

Ionization
Mass spectrometry
Desorption
Imaging techniques
Peptides

The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary

Aujla, P. K., Bora, A., Monahan, P., Sweedler, J. V. & Raetzman, L. T., May 1 2011, In : Developmental Biology. 353, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Neuropeptides
Axons
Supraoptic Nucleus
Paraventricular Hypothalamic Nucleus

Using microfluidics and mass spectrometry to study peptide release in neurons

Croushore, C. A., Lee, C. Y., Zhong, M. & Sweedler, J. V., Dec 1 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. p. 858-860 3 p. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Peptides
Neurons
Mass spectrometry
Silicon wafers
2012

1-methylthio-d-xylulose 5-phosphate methylsulfurylase: A novel route to 1-deoxy-d-xylulose 5-phosphate in Rhodospirillum rubrum

Warlick, B. P., Evans, B. S., Erb, T. J., Ramagopal, U. A., Sriram, J., Imker, H. J., Sauder, J. M., Bonanno, J. B., Burley, S. K., Tabita, F. R., Almo, S. C., Sweedler, J. S. & Gerlt, J. A., Oct 23 2012, In : Biochemistry. 51, 42, p. 8324-8326 3 p.

Research output: Contribution to journalArticle

Rhodospirillum rubrum
Salvaging
S-Adenosylmethionine
Biosynthesis
Terpenes

A hyphenated optical trap capillary electrophoresis laser induced native fluorescence system for single-cell chemical analysis

Cecala, C., Rubakhin, S. S., Mitchell, J. W., Gillette, M. U. & Sweedler, J. V., Jul 7 2012, In : Analyst. 137, 13, p. 2965-2972 8 p.

Research output: Contribution to journalReview article

Optical Tweezers
Single-Cell Analysis
Capillary electrophoresis
Capillary Electrophoresis
chemical analysis

Analyses of pig genomes provide insight into porcine demography and evolution

Groenen, M. A. M., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H. J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C., Auvil, L. & 116 others, Badaoui, B., Beattie, C. W., Bendixen, C., Berman, D., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Bujie, Z., Bystrom, M., Capitanu, B., Carvalho-Silva, D., Chardon, P., Chen, C., Cheng, R., Choi, S. H., Chow, W., Clark, R. C., Clee, C., Crooijmans, R. P. M. A., Dawson, H. D., Dehais, P., De Sapio, F., Dibbits, B., Drou, N., Du, Z. Q., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G. J., Fowler, K. E., Fredholm, M., Fritz, E., Gilbert, J. G. R., Giuffra, E., Gorodkin, J., Griffin, D. K., Harrow, J. L., Hayward, A., Howe, K., Hu, Z. L., Humphray, S. J., Hunt, T., Hornshoøj, H., Jeon, J. T., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Kim, J., Kim, J. H., Kim, K. W., Kim, T. H., Larson, G., Lee, K., Lee, K. T., Leggett, R., Lewin, H. A., Li, Y., Liu, W., Loveland, J. E., Lu, Y., Lunney, J. K., Ma, J., Madsen, O., Mann, K., Matthews, L., McLaren, S., Morozumi, T., Murtaugh, M. P., Narayan, J., Nguyen, D. T., Ni, P., Oh, S. J., Onteru, S., Panitz, F., Park, E. W., Park, H. S., Pascal, G., Paudel, Y., Perez-Enciso, M., Ramirez-Gonzalez, R., Reecy, J. M., Rodriguez-Zas, S., Rohrer, G. A., Rund, L., Sang, Y., Schachtschneider, K., Schraiber, J. G., Schwartz, J., Scobie, L., Scott, C., Searle, S., Servin, B., Southey, B. R., Sperber, G., Stadler, P., Sweedler, J. V., Tafer, H., Thomsen, B., Wali, R., Wang, J., Wang, J., White, S., Xu, X., Yerle, M., Zhang, G., Zhang, J., Zhang, J., Zhao, S., Rogers, J., Churcher, C. & Schook, L. B., Nov 15 2012, In : Nature. 491, 7424, p. 393-398 6 p.

Research output: Contribution to journalArticle

Sus scrofa
Swine
Demography
Genome
Smell

Analytical chemistry: The synergies between the division and the journal

Sweedler, J. V. & Koppenaal, D. W., Nov 6 2012, In : Analytical chemistry. 84, 21, 1 p.

Research output: Contribution to journalEditorial

Chemical analysis

An enhanced protein crosslink identification strategy using CID-cleavable chemical crosslinkers and LC/MS n analysis

Liu, F., Wu, C., Sweedler, J. V. & Goshe, M. B., Feb 1 2012, In : Proteomics. 12, 3, p. 401-405 5 p.

Research output: Contribution to journalComment/debate

Peptides
aspartyl-proline
Proteins
Cross-Linking Reagents
Optical resolving power

A protease for 'middle-down' proteomics

Wu, C., Tran, J. C., Zamdborg, L., Durbin, K. R., Li, M., Ahlf, D. R., Early, B. P., Thomas, P. M., Sweedler, J. V. & Kelleher, N. L., Aug 1 2012, In : Nature Methods. 9, 8, p. 822-824 3 p.

Research output: Contribution to journalArticle

Proteomics
Peptide Hydrolases
Proteolysis
Peptide T
Membranes

Are we growing more picky, more careless or simply under more pressure?

Sweedler, J. V., Aug 7 2012, In : Analytical chemistry. 84, 15, 1 p.

Research output: Contribution to journalEditorial

A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis

Erb, T. J., Evans, B. S., Cho, K., Warlick, B. P., Sriram, J., Wood, B. M. K., Imker, H. J., Sweedler, J. V., Tabita, F. R. & Gerlt, J. A., Nov 2012, In : Nature chemical biology. 8, 11, p. 926-932 7 p.

Research output: Contribution to journalArticle

Oxygenases
Terpenes
Rhodospirillum rubrum
S-Adenosylmethionine
Metabolomics

Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons

Wang, T. A., Yu, Y. V., Govindaiah, G., Ye, X., Artinian, L., Coleman, T. P., Sweedler, J. V., Cox, C. L. & Gillette, M. U., Aug 17 2012, In : Science. 337, 6096, p. 839-842 4 p.

Research output: Contribution to journalArticle

Suprachiasmatic Nucleus
Circadian Rhythm
Neurons
Circadian Clocks
Potassium Channels

Collaborators, colleagues, and friends need not be listed

Sweedler, J. V., May 1 2012, In : Analytical chemistry. 84, 9, 1 p.

Research output: Contribution to journalEditorial

Comparative peptidomics analysis of neural adaptations in rats repeatedly exposed to amphetamine

Romanova, E. V., Lee, J. E., Kelleher, N. L., Sweedler, J. V. & Gulley, J. M., Nov 1 2012, In : Journal of Neurochemistry. 123, 2, p. 276-287 12 p.

Research output: Contribution to journalArticle

Amphetamine
Rats
Peptides
Mass spectrometry
Liquid chromatography

D-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems

Ota, N., Shi, T. & Sweedler, J. V., Nov 1 2012, In : Amino Acids. 43, 5, p. 1873-1886 14 p.

Research output: Contribution to journalReview article

D-Aspartic Acid
Neurosecretory Systems
Nervous System
Molecules
Biosynthesis

Don't grow your article too long: We do have length guidelines

Sweedler, J. V., Jul 3 2012, In : Analytical chemistry. 84, 13, 1 p.

Research output: Contribution to journalEditorial

Evaluation of database search programs for accurate detection of neuropeptides in tandem mass spectrometry experiments

Akhtar, M. N., Southey, B. R., Andrén, P. E., Sweedler, J. V. & Rodriguez-Zas, S. L., Dec 7 2012, In : Journal of Proteome Research. 11, 12, p. 6044-6055 12 p.

Research output: Contribution to journalArticle

Tandem Mass Spectrometry
Neuropeptides
Mass spectrometry
Databases
Peptides

Filling Royce's shoes

Sweedler, J., Jan 3 2012, In : Analytical chemistry. 84, 1, 1 p.

Research output: Contribution to journalEditorial

First survey and functional annotation of prohormone and convertase genes in the pig

Porter, K. I., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., Nov 15 2012, In : BMC genomics. 13, 1, 582.

Research output: Contribution to journalArticle

Proprotein Convertases
Swine
Urocortins
Neuropeptides
Genes

Glial D-serine gates NMDA receptors at excitatory synapses in prefrontal cortex

Fossat, P., Turpin, F. R., Sacchi, S., Dulong, J., Shi, T., Rivet, J. M., Sweedler, J. V., Pollegioni, L., Millan, M. J., Oliet, S. H. R. & Mothet, J. P., Mar 1 2012, In : Cerebral Cortex. 22, 3, p. 595-606 12 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
N-Methyl-D-Aspartate Receptors
Neuroglia
Synapses
Serine

Label-free quantitation of peptide release from neurons in a microfluidic device with mass spectrometry imaging

Zhong, M., Lee, C. Y., Croushore, C. A. & Sweedler, J. V., May 8 2012, In : Lab on a chip. 12, 11, p. 2037-2045 9 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Peptides
Neurons
Mass spectrometry

Let's get social

Sweedler, J. V., Apr 3 2012, In : Analytical chemistry. 84, 7, 1 p.

Research output: Contribution to journalEditorial

Mass spectrometry imaging and profiling of single cells

Lanni, E. J., Rubakhin, S. & Sweedler, J. V., Aug 30 2012, In : Journal of Proteomics. 75, 16, p. 5036-5051 16 p.

Research output: Contribution to journalReview article

Mass spectrometry
Secondary Ion Mass Spectrometry
Mass Spectrometry
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Imaging techniques

Mechanical tension modulates local and global vesicle dynamics in neurons

Ahmed, W. W., Li, T. C., Rubakhin, S., Chiba, A., Sweedler, J. V. & Saif, M. T. A., Jun 1 2012, In : Cellular and Molecular Bioengineering. 5, 2, p. 155-164 10 p.

Research output: Contribution to journalArticle

Vesicles
Aplysia
Drosophila
Neurons
Synaptic Vesicles

Metabolomics in analytical chemistry

Sweedler, J. V., Jul 17 2012, In : Analytical chemistry. 84, 14, 1 p.

Research output: Contribution to journalEditorial

Analytical Chemistry Techniques
Metabolomics
Chemical analysis

Microfluidic device for the selective chemical stimulation of neurons and characterization of peptide release with mass spectrometry

Croushore, C. A., Supharoek, S. A., Lee, C. Y., Jakmunee, J. & Sweedler, J. V., Nov 6 2012, In : Analytical chemistry. 84, 21, p. 9446-9452 7 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Chemical Stimulation
Microfluidics
Neurons
Mass spectrometry

Now it is a highlight, not an acceleration

Sweedler, J. V., Sep 4 2012, In : Analytical chemistry. 84, 17, 1 p.

Research output: Contribution to journalEditorial