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• 2010

  Activation of ERα is necessary for estradiol's anorexigenic effect in female rats

  Santollo, J., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Eckel, L. A., Nov 2010, In: Hormones and Behavior. 58, 5, p. 872-877 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Estradiol
  • Eating
  • Estrogen Receptor Antagonists
  • Hormones

• Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs)

  Kieser, K. J., Kim, D. W., Carlson, K. E., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 22 2010, In: Journal of Medicinal Chemistry. 53, 8, p. 3320-3329 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • acrylic acid
  • Ligands
  • bicyclo(3.3.1)nonane
  • Cyclofenil

• Extranuclear estrogen receptor-α stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

  Wong, W. P. S., Tiano, J. P., Liu, S., Hewitt, S. C., Le May, C., Dalle, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Korach, K. S. & Mauvais-Jarvis, F., Jul 20 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 29, p. 13057-13062 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Insulin
  • Response Elements
  • Islets of Langerhans
  • Estrogens

• Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

  Stender, J. D., Kim, K., Charn, T. H., Komm, B., Chang, K. C. N., Kraus, W. L., Benner, C., Glass, C. K. & Katzenellenbogen, B. S., Aug 2010, In: Molecular and cellular biology. 30, 16, p. 3943-3955 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor alpha
  • Estrogen Receptors
  • Transcriptional Activation
  • Genome
  • Response Elements

• Genome-wide dynamics of chromatin binding of estrogen receptors α and β: Mutual restriction and competitive site selection

  Charn, T. H., Liu, E. T. B., Chang, E. C., Lee, Y. K., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 2010, In: Molecular Endocrinology. 24, 1, p. 47-59 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Chromatin
  • Binding Sites
  • Genome
  • Cytoplasmic and Nuclear Receptors

• Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

  Chambliss, K. L., Wu, Q., Oltmann, S., Konaniah, E. S., Umetani, M., Korach, K. S., Thomas, G. D., Mineo, C., Yuhanna, I. S., Kim, S. H., Madak-Erdogan, Z., Maggi, A., Dineen, S. P., Roland, C. L., Hui, D. Y., Brekken, R. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Shaul, P. W., Jul 1 2010, In: Journal of Clinical Investigation. 120, 7, p. 2319-2330 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Uterine Neoplasms
  • Dendrimers
  • Estrogen Receptors
  • Estrogens
  • Breast Neoplasms

• Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

  Marshall, G. M., Gherardi, S., Xu, N., Neiron, Z., Trahair, T., Scarlett, C. J., Chang, D. K., Liu, P. Y., Jankowski, K., Iraci, N., Haber, M., Norris, M. D., Keating, J., Sekyere, E., Jonquieres, G., Stossi, F., Katzenellenbogen, B. S., Biankin, A. V., Perini, G. & Liu, T., Nov 4 2010, In: Oncogene. 29, 44, p. 5957-5968 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclin G2
  • Histone Deacetylase 2
  • Histone Deacetylases
  • Up-Regulation
  • Neuroblastoma
• 2011

  Estrogen receptor β ligands: Recent advances and biomedical applications

  Minutolo, F., Macchia, M., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., May 2011, In: Medicinal Research Reviews. 31, 3, p. 364-442 79 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Ligands
  • Non-Steroidal Estrogens
  • Endometriosis
  • Cytoplasmic and Nuclear Receptors

• Estrogen-regulated prohibitin is required for mouse uterine development and adult function

  He, B., Kim, T. H., Kommagani, R., Feng, Q., Lanz, R. B., Jeong, J. W., DeMayo, F. J., Katzenellenbogen, B. S., Lydon, J. P. & O'Malley, B. W., Mar 2011, In: Endocrinology. 152, 3, p. 1047-1056 10 p.

  Research output: Contribution to journal › Article › peer-review

  • prohibitin
  • Estrogens
  • Estrogen Receptors
  • Uterus
  • Steroid Receptors

• Genomic collaboration of estrogen receptor α and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs

  Madak-Erdogan, Z., Lupien, M., Stossi, F., Brown, M. & Katzenellenbogen, B. S., Jan 2011, In: Molecular and cellular biology. 31, 1, p. 226-236 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitogen-Activated Protein Kinase 1
  • Estrogen Receptors
  • Genes
  • Cytoplasmic and Nuclear Receptors
  • Mitogen-Activated Protein Kinases

• Repressor of Estrogen Receptor Activity (REA) is essential for mammary gland morphogenesis and functional activities: Studies in conditional knockout mice

  Park, S., Zhao, Y., Yoon, S., Xu, J., Liao, L., Lydon, J., DeMayo, F., O'Malley, B. W. & Katzenellenbogen, B. S., Nov 2011, In: Endocrinology. 152, 11, p. 4336-4349 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Mammary Glands
  • Morphogenesis
  • Estrogen Receptors
  • Knockout Mice
  • Breast

• Reversal of endocrine resistance in breast cancer: Interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

  Bergamaschi, A., Christensen, B. L. & Katzenellenbogen, B. S., Jun 29 2011, In: Breast Cancer Research. 13, 3, R70.

  Research output: Contribution to journal › Article › peer-review

  • Mitosis
  • Breast Neoplasms
  • Estrogen Receptors
  • Genes
  • Aurora Kinase B

• The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

  Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In: Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptor alpha
  • Estrogen Receptors
  • Estrogens
  • Transcription Factors
  • Breast Neoplasms
• 2014

  Endocrine Society 2014 Laureate Awards

  Gustafsson, J. A., Katzenellenbogen, B., Jameson, J. L., Roth, J., Melmed, S., McDonnell, D., Wartofsky, L., Crowley, W. F., Griz, L. H. E., Becker, C., Moore, D. D., Drucker, D., Singh, N. & O'Malley, B., Oct 1 2014, In: Hormones & cancer. 5, 5, p. 339-355 17 p.

  Research output: Contribution to journal › Article › peer-review

• Estrogen-induced CCN1 Is critical for establishment of endometriosis-like lesions in mice

  Zhao, Y., Li, Q., Katzenellenbogen, B. S., Lau, L. F., Taylor, R. N., Bagchi, I. C. & Bagchi, M. K., 2014, In: Molecular Endocrinology. 28, 12, p. 1934-1947 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Endometriosis
  • Estrogens
  • Choristoma
  • Vascular Endothelial Growth Factor C
  • Cell Proliferation

• Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells

  Clark, S., Rainville, J., Zhao, X., Katzenellenbogen, B. S., Pfaff, D. & Vasudevan, N., 2014, In: Journal of Steroid Biochemistry and Molecular Biology. 139, p. 45-53 9 p.

  Research output: Contribution to journal › Article › peer-review

  • estradiol-bovine serum albumin
  • Transcription
  • Neuroblastoma
  • Estrogen Receptors
  • Transcriptional Activation

• Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

  Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Jan 1 2014, In: In Vitro Cellular and Developmental Biology - Animal. 51, 1, p. 59-71 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dioscorea
  • 5-methyldeoxycytidine
  • 5-hydroxymethylcytosine
  • Epigenomics
  • MCF-7 Cells

• Highly sensitive quantitative imaging for monitoring single cancer cell growth kinetics and drug response

  Mir, M., Bergamaschi, A., Katzenellenbogen, B. S. & Popescu, G., Feb 18 2014, In: PloS one. 9, 2, e89000.

  Research output: Contribution to journal › Article › peer-review

  • Light interference
  • Growth kinetics
  • Cell growth
  • Microscopic examination
  • Cells

• Integration of molecular profiling and chemical imaging to elucidate fibroblast-microenvironment impact on cancer cell phenotype and endocrine resistance in breast cancer

  Holton, S. E., Bergamaschi, A., Katzenellenbogen, B. S. & Bhargava, R., May 9 2014, In: PloS one. 9, 5, e96878.

  Research output: Contribution to journal › Article › peer-review

  • Fibroblasts
  • Endocrine Cells
  • breast neoplasms
  • Cells
  • neoplasm cells

• Novel roles for ERK5 and cofilin as critical mediators linking ERα-driven transcription, actin reorganization, and invasiveness in breast cancer

  Madak-Erdogan, Z., Ventrella, R., Petry, L. & Katzenellenbogen, B. S., May 2014, In: Molecular Cancer Research. 12, 5, p. 714-727 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Actin Depolymerizing Factors
  • Estrogen Receptors
  • Actins
  • Breast Neoplasms
  • Hormones

• The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells

  Bergamaschi, A., Madak-Erdogan, Z., Kim, Y. J., Choi, Y. L., Lu, H. & Katzenellenbogen, B. S., 2014, In: Breast Cancer Research. 16, 1, 436.

  Research output: Contribution to journal › Article › peer-review

  • Forkhead Transcription Factors
  • Neoplastic Stem Cells
  • Estrogen Receptors
  • Breast Neoplasms
  • Forkhead Box Protein M1

• The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

  Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valéra, M. C., Gompel, A., Gerard, C., Péqueux, C., Mestdagt, M., Raymond-Letron, I., Knauf, C. & 9 others, Ferriere, F., Valet, P., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Lenfant, F., Greene, G. L., Foidart, J. M. & Arnal, J. F., Oct 1 2014, In: EMBO Molecular Medicine. 6, 10, p. 1328-1346 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Estetrol
  • Nuclear Envelope
  • Estrogen Receptors
  • Blood Vessels
  • Furylfuramide

• Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens

  Gong, P., Madak-Erdogan, Z., Li, J., Cheng, J., Greenlief, C. M., Helferich, W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., 2014, In: Nuclear receptor signaling. 12, p. e001

  Research output: Contribution to journal › Article › peer-review

  • Gene Regulatory Networks
  • Estrogen Receptors
  • Estrogens
  • Gene Expression
  • Glycyrrhiza
• 2016

  Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

  Madak-Erdogan, Z., Kim, S. H., Gong, P., Zhao, Y. C., Zhang, H., Chambliss, K. L., Carlson, K. E., Mayne, C. G., Shaul, P. W., Korach, K. S., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., May 24 2016, In: Science Signaling. 9, 429, ra53.

  Research output: Contribution to journal › Article › peer-review

  • Tissue
  • Estrogens
  • Blood Vessels
  • Ligands
  • Estrogen Receptors

• Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland

  Madak-Erdogan, Z., Gong, P., Zhao, Y. C., Xu, L., Wrobel, K. U., Hartman, J. A., Wang, M., Cam, A., Iwaniec, U. T., Turner, R. T., Twaddle, N. C., Doerge, D. R., Khan, I. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Helferich, W. G., Feb 1 2016, In: Molecular Nutrition and Food Research. 60, 2, p. 369-380 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Glycyrrhiza
  • licorice
  • fatty liver
  • isoliquiritigenin
  • Human Mammary Glands

• Differential utilization of nuclear and extranuclear receptor signaling pathways in the actions of estrogens, SERMs, and a tissue-selective estrogen complex (TSEC)

  Madak-Erdogan, Z., Gong, P. & Katzenellenbogen, B. S., Apr 1 2016, In: Journal of Steroid Biochemistry and Molecular Biology. 158, p. 198-206 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Conjugated (USP) Estrogens
  • Selective Estrogen Receptor Modulators
  • Cytoplasmic and Nuclear Receptors
  • Tissue
  • Estrogens

• Endocrine treatment in breast cancer: Cure, resistance and beyond

  Tryfonidis, K., Zardavas, D., Katzenellenbogen, B. S. & Piccart, M., Nov 1 2016, In: Cancer Treatment Reviews. 50, p. 68-81 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Breast Neoplasms
  • Tumor Microenvironment
  • Therapeutics
  • Hormones
  • Biomarkers

• Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

  Fanning, S. W., Mayne, C. G., Dharmarajan, V., Carlson, K. E., Martin, T. A., Novick, S. J., Toy, W., Green, B., Panchamukhi, S., Katzenellenbogen, B. S., Tajkhorshid, E., Griffin, P. R., Shen, Y., Chandarlapaty, S., Katzenellenbogen, J. A. & Greene, G. L., Feb 2 2016, In: eLife. 5, FEBRUARY2016, e12792.

  Research output: Contribution to journal › Article › peer-review

  • Conformations
  • Estrogen Receptor alpha
  • Estrogen Receptor Modulators
  • Breast Neoplasms
  • Mutation

• Estrogen receptor-α and aryl hydrocarbon receptor involvement in the actions of botanical estrogens in target cells

  Gong, P., Madak-Erdogan, Z., Flaws, J. A., Shapiro, D. J., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 5 2016, In: Molecular and Cellular Endocrinology. 437, p. 190-200 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aryl Hydrocarbon Receptors
  • Estrogen Receptors
  • Estrogens
  • Gene expression
  • Crosstalk

• Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities

  Boonmuen, N., Gong, P., Ali, Z., Chittiboyina, A. G., Khan, I., Doerge, D. R., Helferich, W. G., Carlson, K. E., Martin, T., Piyachaturawat, P., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2016, In: Steroids. 105, p. 42-49 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary supplements
  • liquiritigenin
  • isoliquiritigenin
  • Glycyrrhiza
  • Selective Estrogen Receptor Modulators

• Multiple beneficial roles of repressor of estrogen receptor activity (REA) in suppressing the progression of endometriosis

  Zhao, Y., Chen, Y., Kuang, Y., Bagchi, M. K., Taylor, R. N., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Feb 2016, In: Endocrinology. 157, 2, p. 900-912 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Endometriosis
  • Estrogen Receptors
  • Tissue Donors
  • prohibitin
  • Estradiol Receptors

• Nonnuclear estrogen receptor activation improves hepatic steatosis in female mice

  Chambliss, K. L., Barrera, J., Umetani, M., Umetani, J., Kim, S. H., Madak-Erdogan, Z., Huang, L., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C. & Shaul, P. W., 2016, In: Endocrinology. 157, 10, p. 3731-3741 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendrimers
  • Estrogen Receptors
  • Estrogens
  • Liver
  • Adiposity

• OCT-4: A novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells

  Bhatt, S., Stender, J. D., Joshi, S., Wu, G. & Katzenellenbogen, B. S., Nov 3 2016, In: Oncogene. 35, 44, p. 5722-5734 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Tamoxifen
  • Estrogen Receptors
  • Breast Neoplasms
  • Binding Sites
  • MCF-7 Cells

• Science Signaling podcast for 24 May 2016: Designer estrogens

  Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In: Science Signaling. 9, 429, pc13.

  Research output: Contribution to journal › Review article › peer-review

  • Webcasts
  • Estrogens
  • Metabolism
  • Bone
  • Estradiol Congeners

• The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

  Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In: Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

  Research output: Contribution to journal › Article › peer-review

  • dioscin
  • Dioscorea
  • Saponins
  • Cells
  • Breast Neoplasms
• 2019

  Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

  Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In: npj Breast Cancer. 5, 1, 45.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Breast Neoplasms
  • Growth
  • Forkhead Box Protein M1
  • In Vitro Techniques
  • Triple Negative Breast Neoplasms