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Author

  • Benita S Katzenellenbogen
2010

Activation of ERα is necessary for estradiol's anorexigenic effect in female rats

Santollo, J., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Eckel, L. A., Nov 1 2010, In : Hormones and Behavior. 58, 5, p. 872-877 6 p.

Research output: Contribution to journalArticle

Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs)

Kieser, K. J., Kim, D. W., Carlson, K. E., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 22 2010, In : Journal of Medicinal Chemistry. 53, 8, p. 3320-3329 10 p.

Research output: Contribution to journalArticle

Extranuclear estrogen receptor-α stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

Wong, W. P. S., Tiano, J. P., Liu, S., Hewitt, S. C., Le May, C., Dalle, S., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Korach, K. S. & Mauvais-Jarvis, F., Jul 20 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 29, p. 13057-13062 6 p.

Research output: Contribution to journalArticle

Genome-wide analysis of estrogen receptor α DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

Stender, J. D., Kim, K., Charn, T. H., Komm, B., Chang, K. C. N., Kraus, W. L., Benner, C., Glass, C. K. & Katzenellenbogen, B. S., Aug 1 2010, In : Molecular and cellular biology. 30, 16, p. 3943-3955 13 p.

Research output: Contribution to journalArticle

Genome-wide dynamics of chromatin binding of estrogen receptors α and β: Mutual restriction and competitive site selection

Charn, T. H., Liu, E. T. B., Chang, E. C., Lee, Y. K., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2010, In : Molecular Endocrinology. 24, 1, p. 47-59 13 p.

Research output: Contribution to journalArticle

Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

Chambliss, K. L., Wu, Q., Oltmann, S., Konaniah, E. S., Umetani, M., Korach, K. S., Thomas, G. D., Mineo, C., Yuhanna, I. S., Kim, S. H., Madak-Erdogan, Z., Maggi, A., Dineen, S. P., Roland, C. L., Hui, D. Y., Brekken, R. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Shaul, P. W., Jul 1 2010, In : Journal of Clinical Investigation. 120, 7, p. 2319-2330 12 p.

Research output: Contribution to journalArticle

Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

Marshall, G. M., Gherardi, S., Xu, N., Neiron, Z., Trahair, T., Scarlett, C. J., Chang, D. K., Liu, P. Y., Jankowski, K., Iraci, N., Haber, M., Norris, M. D., Keating, J., Sekyere, E., Jonquieres, G., Stossi, F., Katzenellenbogen, B. S., Biankin, A. V., Perini, G. & Liu, T., Nov 4 2010, In : Oncogene. 29, 44, p. 5957-5968 12 p.

Research output: Contribution to journalArticle

2011

Estrogen receptor β ligands: Recent advances and biomedical applications

Minutolo, F., Macchia, M., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., May 1 2011, In : Medicinal Research Reviews. 31, 3, p. 364-442 79 p.

Research output: Contribution to journalArticle

Estrogen-regulated prohibitin is required for mouse uterine development and adult function

He, B., Kim, T. H., Kommagani, R., Feng, Q., Lanz, R. B., Jeong, J. W., DeMayo, F. J., Katzenellenbogen, B. S., Lydon, J. P. & O'Malley, B. W., Mar 2011, In : Endocrinology. 152, 3, p. 1047-1056 10 p.

Research output: Contribution to journalArticle

Repressor of Estrogen Receptor Activity (REA) is essential for mammary gland morphogenesis and functional activities: Studies in conditional knockout mice

Park, S., Zhao, Y., Yoon, S., Xu, J., Liao, L., Lydon, J., DeMayo, F., O'Malley, B. W. & Katzenellenbogen, B. S., Nov 2011, In : Endocrinology. 152, 11, p. 4336-4349 14 p.

Research output: Contribution to journalArticle

Reversal of endocrine resistance in breast cancer: Interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis

Bergamaschi, A., Christensen, B. L. & Katzenellenbogen, B. S., Jun 29 2011, In : Breast Cancer Research. 13, 3, R70.

Research output: Contribution to journalArticle

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In : Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

2013

14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers

Bergamaschi, A., Frasor, J., Borgen, K., Stanculescu, A., Johnson, P., Rowland, K., Wiley, E. L. & Katzenellenbogen, B. S., Feb 1 2013, In : Breast Cancer Research and Treatment. 137, 3, p. 689-696 8 p.

Research output: Contribution to journalArticle

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

Madak-Erdogan, Z., Charn, T. H., Jiang, Y., Liu, E. T., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2013, In : Molecular Systems Biology. 9, 201328.

Research output: Contribution to journalArticle

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

Jiang, Y., Gong, P., Madak-Erdogan, Z., Martin, T., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T. J., Chittiboyina, A. G., Rotte, S. C. K., Helferich, W. G., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Nov 1 2013, In : FASEB Journal. 27, 11, p. 4406-4418 13 p.

Research output: Contribution to journalArticle

Non-nuclear-initiated actions of the estrogen receptor protect cortical bone mass

Bartell, S. M., Han, L., Kim, H. N., Kim, S. H., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Chambliss, K. L., Shaul, P. W., Roberson, P. K., Weinstein, R. S., Jilka, R. L., Almeida, M. & Manolagas, S. C., Apr 1 2013, In : Molecular Endocrinology. 27, 4, p. 649-656 8 p.

Research output: Contribution to journalArticle

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In : Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journalArticle

2014

Endocrine Society 2014 Laureate Awards

Gustafsson, J. A., Katzenellenbogen, B., Jameson, J. L., Roth, J., Melmed, S., McDonnell, D., Wartofsky, L., Crowley, W. F., Griz, L. H. E., Becker, C., Moore, D. D., Drucker, D., Singh, N. & O'Malley, B., Oct 1 2014, In : Hormones & cancer. 5, 5, p. 339-355 17 p.

Research output: Contribution to journalArticle

Estrogen-induced CCN1 Is critical for establishment of endometriosis-like lesions in mice

Zhao, Y., Li, Q., Katzenellenbogen, B. S., Lau, L. F., Taylor, R. N., Bagchi, I. C. & Bagchi, M. K., 2014, In : Molecular Endocrinology. 28, 12, p. 1934-1947 14 p.

Research output: Contribution to journalArticle

Estrogen receptor-mediated transcription involves the activation of multiple kinase pathways in neuroblastoma cells

Clark, S., Rainville, J., Zhao, X., Katzenellenbogen, B. S., Pfaff, D. & Vasudevan, N., Jan 1 2014, In : Journal of Steroid Biochemistry and Molecular Biology. 139, p. 45-53 9 p.

Research output: Contribution to journalArticle

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Jan 1 2014, In : In Vitro Cellular and Developmental Biology - Animal. 51, 1, p. 59-71 13 p.

Research output: Contribution to journalArticle

Highly sensitive quantitative imaging for monitoring single cancer cell growth kinetics and drug response

Mir, M., Bergamaschi, A., Katzenellenbogen, B. S. & Popescu, G., Feb 18 2014, In : PloS one. 9, 2, e89000.

Research output: Contribution to journalArticle

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valéra, M. C., Gompel, A., Gerard, C., Péqueux, C., Mestdagt, M., Raymond-Letron, I., Knauf, C. & 9 others, Ferriere, F., Valet, P., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Lenfant, F., Greene, G. L., Foidart, J. M. & Arnal, J. F., Oct 1 2014, In : EMBO Molecular Medicine. 6, 10, p. 1328-1346 19 p.

Research output: Contribution to journalArticle

2015

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

Zhao, Y., Gong, P., Chen, Y., Nwachukwu, J. C., Srinivasan, S., Ko, C. M., Bagchi, M. K., Taylor, R. N., Korach, K. S., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 21 2015, In : Science Translational Medicine. 7, 271, 271ra9.

Research output: Contribution to journalArticle

Highly selective salicylketoxime-based estrogen receptor β agonists display antiproliferative activities in a glioma model

Paterni, I., Bertini, S., Granchi, C., Tuccinardi, T., Macchia, M., Martinelli, A., Caligiuri, I., Toffoli, G., Rizzolio, F., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Minutolo, F., Feb 12 2015, In : Journal of Medicinal Chemistry. 58, 3, p. 1184-1194 11 p.

Research output: Contribution to journalArticle

Ligand accessibility and bioactivity of a hormone-dendrimer conjugate depend on pH and pH history

Kim, S. H., Madak-Erdogan, Z., Bae, S. C., Carlson, K. E., Mayne, C. G., Granick, S., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Aug 19 2015, In : Journal of the American Chemical Society. 137, 32, p. 10326-10335 10 p.

Research output: Contribution to journalArticle

Protective hematopoietic effect of estrogens in a mouse model of thrombosis: Respective roles of nuclear versus membrane estrogen receptor α

Valera, M. C., Fontaine, C., Lenfant, F., Cabou, C., Guillaume, M., Smirnova, N., Kim, S. H., Chambon, P., Katzenellenbogen, J. A., Katzenellenbogen, B. S., Payrastre, B. & Arnal, J. F., Nov 2015, In : Endocrinology. 156, 11, p. 4293-4301 9 p.

Research output: Contribution to journalArticle

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In : Nature communications. 6, 8303.

Research output: Contribution to journalArticle

The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In : Circulation Research. 117, 9, p. 770-777 8 p.

Research output: Contribution to journalArticle

2016

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

Madak-Erdogan, Z., Kim, S. H., Gong, P., Zhao, Y. C., Zhang, H., Chambliss, K. L., Carlson, K. E., Mayne, C. G., Shaul, P. W., Korach, K. S., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., May 24 2016, In : Science Signaling. 9, 429, ra53.

Research output: Contribution to journalArticle

Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland

Madak-Erdogan, Z., Gong, P., Zhao, Y. C., Xu, L., Wrobel, K. U., Hartman, J. A., Wang, M., Cam, A., Iwaniec, U. T., Turner, R. T., Twaddle, N. C., Doerge, D. R., Khan, I. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Helferich, W. G., Feb 1 2016, In : Molecular Nutrition and Food Research. 60, 2, p. 369-380 12 p.

Research output: Contribution to journalArticle

Endocrine treatment in breast cancer: Cure, resistance and beyond

Tryfonidis, K., Zardavas, D., Katzenellenbogen, B. S. & Piccart, M., Nov 1 2016, In : Cancer Treatment Reviews. 50, p. 68-81 14 p.

Research output: Contribution to journalReview article

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

Fanning, S. W., Mayne, C. G., Dharmarajan, V., Carlson, K. E., Martin, T. A., Novick, S. J., Toy, W., Green, B., Panchamukhi, S., Katzenellenbogen, B. S., Tajkhorshid, E., Griffin, P. R., Shen, Y., Chandarlapaty, S., Katzenellenbogen, J. A. & Greene, G. L., Feb 2 2016, In : eLife. 5, FEBRUARY2016, e12792.

Research output: Contribution to journalArticle

Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities

Boonmuen, N., Gong, P., Ali, Z., Chittiboyina, A. G., Khan, I., Doerge, D. R., Helferich, W. G., Carlson, K. E., Martin, T., Piyachaturawat, P., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2016, In : Steroids. 105, p. 42-49 8 p.

Research output: Contribution to journalArticle

Multiple beneficial roles of repressor of estrogen receptor activity (REA) in suppressing the progression of endometriosis

Zhao, Y., Chen, Y., Kuang, Y., Bagchi, M. K., Taylor, R. N., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Feb 2016, In : Endocrinology. 157, 2, p. 900-912 13 p.

Research output: Contribution to journalArticle

Nonnuclear estrogen receptor activation improves hepatic steatosis in female mice

Chambliss, K. L., Barrera, J., Umetani, M., Umetani, J., Kim, S. H., Madak-Erdogan, Z., Huang, L., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C. & Shaul, P. W., Jan 1 2016, In : Endocrinology. 157, 10, p. 3731-3741 11 p.

Research output: Contribution to journalArticle

OCT-4: A novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells

Bhatt, S., Stender, J. D., Joshi, S., Wu, G. & Katzenellenbogen, B. S., Nov 3 2016, In : Oncogene. 35, 44, p. 5722-5734 13 p.

Research output: Contribution to journalArticle

Science Signaling podcast for 24 May 2016: Designer estrogens

Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In : Science Signaling. 9, 429, pc13.

Research output: Contribution to journalReview article

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In : Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

Research output: Contribution to journalArticle

2017

Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells

Min, J., Guillen, V. S., Sharma, A., Zhao, Y., Ziegler, Y., Gong, P., Mayne, C. G., Srinivasan, S., Kim, S. H., Carlson, K. E., Nettles, K. W., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Jul 27 2017, In : Journal of Medicinal Chemistry. 60, 14, p. 6321-6336 16 p.

Research output: Contribution to journalArticle

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

Nelson, A. W., Groen, A. J., Miller, J. L., Warren, A. Y., Holmes, K. A., Tarulli, G. A., Tilley, W. D., Katzenellenbogen, B. S., Hawse, J. R., Gnanapragasam, V. J. & Carroll, J. S., Jan 15 2017, In : Molecular and Cellular Endocrinology. 440, p. 138-150 13 p.

Research output: Contribution to journalArticle