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2013

Combining small-volume metabolomic and transcriptomic approaches for assessing brain chemistry

Knolhoff, A. M., Nautiyal, K. M., Nemes, P., Kalachikov, S., Morozova, I., Silver, R. & Sweedler, J. V., Mar 19 2013, In : Analytical chemistry. 85, 6, p. 3136-3143 8 p.

Research output: Contribution to journalArticle

Metabolites
Capillary electrophoresis
Brain
Biological systems
Gene expression

Correlated imaging-a grand challenge in chemical analysis

Masyuko, R., Lanni, E. J., Sweedler, J. V. & Bohn, P. W., Apr 7 2013, In : Analyst. 138, 7, p. 1924-1939 16 p.

Research output: Contribution to journalReview article

chemical analysis
Imaging techniques
Chemical analysis
experiment
Experiments

Details matter, and so do statistics

Sweedler, J. V., Jun 4 2013, In : Analytical chemistry. 85, 11, 1 p.

Research output: Contribution to journalEditorial

Statistics

Discovery of new enzymes and metabolic pathways by using structure and genome context

Zhao, S., Kumar, R., Sakai, A., Vetting, M. W., Wood, B. M. K., Brown, S., Bonanno, J. B., Hillerich, B. S., Seidel, R. D., Babbitt, P. C., Almo, S. C., Sweedler, J. V., Gerlt, J. A., Cronan, J. E. & Jacobson, M. P., Sep 24 2013, In : Nature. 502, 7473, p. 698-702 5 p.

Research output: Contribution to journalArticle

Metabolic Networks and Pathways
Genome
Multigene Family
Substrate Specificity
Enzymes
Lab-On-A-Chip Devices
Detergents
Neurites
Microfluidics
Neurons

Meet our second advisory board, the analytical chemistry features panel

Sweedler, J. V., Aug 20 2013, In : Analytical chemistry. 85, 16, 1 p.

Research output: Contribution to journalEditorial

Chemical analysis

Meet the Analytical Chemistry editorial advisory board

Sweedler, J. V., Feb 5 2013, In : Analytical chemistry. 85, 3, 1 p.

Research output: Contribution to journalEditorial

Chemical analysis

Microfluidic systems for studying neurotransmitters and neurotransmission

Croushore, C. A. & Sweedler, J. V., May 7 2013, In : Lab on a Chip. 13, 9, p. 1666-1676 11 p.

Research output: Contribution to journalReview article

Microfluidics
Synaptic Transmission
Neurotransmitter Agents
Molecules
Cell signaling

Multifactorial understanding of ion abundance in tandem mass spectrometry experiments

Fazal, Z., Southey, B. R., Sweedler, J. V. & Rodriguez-Zas, S. L., Mar 12 2013, In : Journal of Proteomics and Bioinformatics. 6, 2, p. 23-29 7 p.

Research output: Contribution to journalArticle

Tandem Mass Spectrometry
Mass spectrometry
Ions
Peptides
Experiments

New Mass Spectrometric Approaches for Uncovering Neuropeptides

Hou, X. & Sweedler, J. V., Aug 29 2013, Handbook of Biologically Active Peptides. Elsevier Inc., p. 1749-1756 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neuropeptides

Pittcon: Still vibrant after more than 60 years

Sweedler, J. V., Mar 5 2013, In : Analytical chemistry. 85, 5, 1 p.

Research output: Contribution to journalEditorial

Progress toward single cell metabolomics

Rubakhin, S. S., Lanni, E. J. & Sweedler, J. V., Feb 1 2013, In : Current Opinion in Biotechnology. 24, 1, p. 95-104 10 p.

Research output: Contribution to journalReview article

Metabolomics
Metabolites
Molecules
Microfluidics
Mass spectrometry
Capillary electrophoresis
Electrospray ionization
Metabolomics
Electrospray Ionization Mass Spectrometry
Capillary Electrophoresis

Quantitation of endogenous peptides using mass spectrometry based methods

Romanova, E. V., Dowd, S. E. & Sweedler, J. V., Oct 1 2013, In : Current Opinion in Chemical Biology. 17, 5, p. 801-808 8 p.

Research output: Contribution to journalReview article

Mass spectrometry
Mass Spectrometry
Peptides
Data Mining
Molecular interactions

Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus

Lee, J. E., Zamdborg, L., Southey, B. R., Atkins, N., Mitchell, J. W., Li, M., Gillette, M. U., Kelleher, N. L. & Sweedler, J. V., Feb 1 2013, In : Journal of Proteome Research. 12, 2, p. 585-593 9 p.

Research output: Contribution to journalArticle

Suprachiasmatic Nucleus
Rats
Peptides
Optic Chiasm
Circadian Clocks

Quantitative reflection imaging of fixed aplysia californica pedal ganglion neurons on nanostructured plasmonic crystals

Le, A. P., Kang, S., Thompson, L. B., Rubakhin, S. S., Sweedler, J. V., Rogers, J. A. & Nuzzo, R. G., Nov 4 2013, In : Journal of Physical Chemistry B. 117, 42, p. 13069-13081 13 p.

Research output: Contribution to journalArticle

pedals
Aplysia
Surface Plasmon Resonance
Surface plasmon resonance
neurons

Reflections from my first year

Sweedler, J. V., Jan 2 2013, In : Analytical chemistry. 85, 1, 1 p.

Research output: Contribution to journalEditorial

Signals from the Brainstem Sleep/Wake Centers Regulate Behavioral Timing via the Circadian Clock

Abbott, S. M., Arnold, J. M., Chang, Q., Miao, H., Ota, N., Cecala, C., Gold, P. E., Sweedler, J. V. & Gillette, M. L., Aug 12 2013, In : PloS one. 8, 8, e70481.

Research output: Contribution to journalArticle

Circadian Clocks
Suprachiasmatic Nucleus
brain stem
sleep
circadian rhythm

Stimulation and release from neurons via a dual capillary collection device interfaced to mass spectrometry

Fan, Y., Lee, C. Y., Rubakhin, S. S. & Sweedler, J. V., Nov 7 2013, In : Analyst. 138, 21, p. 6337-6346 10 p.

Research output: Contribution to journalArticle

peptide
Peptides
Neurons
Mass spectrometry
Mass Spectrometry

Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission

Martineau, M., Shi, T., Puyal, J., Knolhoff, A. M., Dulong, J., Gasnier, B., Klingauf, J., Sweedler, J. V., Jahn, R. & Mothet, J. P., Feb 20 2013, In : Journal of Neuroscience. 33, 8, p. 3413-3423 11 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Serine
Glutamic Acid
Astrocytes
SNARE Proteins

Tips on writing a postdoctoral request letter

Sweedler, J. V., Aug 6 2013, In : Analytical chemistry. 85, 15, 1 p.

Research output: Contribution to journalEditorial

Visualizing the proteome: Mapping protein changes in disease states with mass spectrometry imaging

Lanni, E. J., Rubakhin, S. & Sweedler, J. V., Mar 1 2013, In : Journal of Neurochemistry. 124, 5, p. 581-583 3 p.

Research output: Contribution to journalReview article

Neuroimaging
Proteome
Mass spectrometry
Imaging techniques
Proteins
2014
Chemical analysis

Accurate assignment of significance to neuropeptide identifications using monte carlo K-permuted decoy databases

Akhtar, M. N., Southey, B. R., Andrén, P. E., Sweedler, J. V. & Rodriguez-Zas, S. L., Oct 17 2014, In : PloS one. 9, 10, e111112.

Research output: Contribution to journalArticle

neuropeptides
Neuropeptides
Databases
testing
peptides

Analysis of endogenous nucleotides by single cell capillary electrophoresis-mass spectrometry

Liu, J. X., Aerts, J. T., Rubakhin, S. S., Zhang, X. X. & Sweedler, J. V., Oct 15 2014, In : Analyst. 139, 22, p. 5835-5842 8 p.

Research output: Contribution to journalArticle

Aplysia
Capillary electrophoresis
Capillary Electrophoresis
Nucleotides
Neurons

Application of capillary electrophoresis for the early diagnosis of cancer

Yang, Z. & Sweedler, J. V., Jul 2014, In : Analytical and bioanalytical chemistry. 406, 17, p. 4013-4031 19 p.

Research output: Contribution to journalReview article

Capillary electrophoresis
Capillary Electrophoresis
Early Detection of Cancer
Microchip Electrophoresis
Biomarkers

Around the world with analytical chemistry

Sweedler, J. V., May 6 2014, In : Analytical chemistry. 86, 9, 1 p.

Research output: Contribution to journalEditorial

Chemical analysis
Single-Cell Analysis
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Biomolecules
Mass spectrometers
Ion sources

Chemistry and the BRAIN initiative

Andrews, A. M., Schepartz, A., Sweedler, J. V. & Weiss, P. S., Jan 8 2014, In : Journal of the American Chemical Society. 136, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Brain Chemistry
Neurosciences
Brain

Comparing label-free quantitative peptidomics approaches to characterize diurnal variation of peptides in the rat suprachiasmatic nucleus

Southey, B. R., Lee, J. E., Zamdborg, L., Atkins, N., Mitchell, J. W., Li, M., Gillette, M. U., Kelleher, N. L. & Sweedler, J. V., Jan 7 2014, In : Analytical chemistry. 86, 1, p. 443-452 10 p.

Research output: Contribution to journalArticle

Rats
Labels
Peptides
Neuropeptides
Secretogranin II

Correction: Spatial organization of Pseudomonas aeruginosa biofilms probed by combined matrix-assisted laser desorption ionization mass spectrometry and confocal raman microscopy

Masyuko, R. N., Lanni, E. J., Driscoll, C. M., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 15 2014, In : Analyst. 139, 22, p. 6058-6060 3 p.

Research output: Contribution to journalArticle

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Biofilms
Confocal Microscopy
Pseudomonas aeruginosa
Ionization

Correlated imaging with C60-SIMS and confocal raman microscopy: Visualization of cell-scale molecular distributions in bacterial biofilms

Lanni, E. J., Masyuko, R. N., Driscoll, C. M., Dunham, S. J. B., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Sep 30 2014, In : Analytical chemistry. 86, 21, p. 10885-10891 7 p.

Research output: Contribution to journalArticle

Biofilms
Secondary ion mass spectrometry
Microscopic examination
Visualization
Quinolones

D-Alanine in the islets of Langerhans of rat pancreas

Ota, N., Rubakhin, S. & Sweedler, J. V., May 2 2014, In : Biochemical and Biophysical Research Communications. 447, 2, p. 328-333 6 p.

Research output: Contribution to journalArticle

Islets of Langerhans
Alanine
Rats
Pancreas
Glucose

Editorial

Suzuki, K., Teramae, N., Hattori, S., Copsey, M. & Sweedler, J. V., Jan 2014, In : Analytical Sciences. 30, 1, p. 1-5 5 p.

Research output: Contribution to journalEditorial

Evaluation of significance level assignment of database search programs using monte carlo permutation approach

Akhtar, M. N., Southey, B. R., Andrén, P. E., Sweedler, J. V. & Rodriguez-Zas, S. L., Jan 1 2014, Proceedings of the 6th International Conference on Bioinformatics and Computational Biology, BICOB 2014. International Society for Computers and Their Applications, p. 103-107 5 p. (Proceedings of the 6th International Conference on Bioinformatics and Computational Biology, BICOB 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Databases
Peptides
Neuropeptides
Tandem Mass Spectrometry
Mass spectrometry

Fibrinogen α-chain-derived peptide is upregulated in hippocampus of rats exposed to acute morphine injection and spontaneous alternation testing

Maki, A. E., Morris, K. A., Catherman, K., Chen, X., Hatcher, N. G., Gold, P. E. & Sweedler, J. V., Jun 2014, In : Pharmacology Research and Perspectives. 2, 3, e00037.

Research output: Contribution to journalArticle

Fibrinopeptide A
Fibrinogen
Morphine
Hippocampus
Peptides

Identification of best indicators of peptide-spectrum match using a permutation resampling approach

Akhtar, M. N., Southey, B. R., Andrén, P. E., Sweedler, J. V. & Rodriguez-Zas, S. L., Oct 30 2014, In : Journal of Bioinformatics and Computational Biology. 12, 5, 1440001.

Research output: Contribution to journalArticle

Peptides
Databases
Software

MALDI-guided SIMS: Multiscale imaging of metabolites in bacterial biofilms

Lanni, E. J., Masyuko, R. N., Driscoll, C. M., Aerts, J. T., Shrout, J. D., Bohn, P. W. & Sweedler, J. V., Sep 1 2014, In : Analytical chemistry. 86, 18, p. 9139-9145 7 p.

Research output: Contribution to journalArticle

Biofilms
Secondary ion mass spectrometry
Metabolites
Ionization
Desorption

Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization

Aerts, J. T., Louis, K. R., Crandall, S. R., Govindaiah, G., Cox, C. L. & Sweedler, J. V., Jan 1 2014, In : Analytical chemistry. 86, 6, p. 3203-3208 6 p.

Research output: Contribution to journalArticle

Electrophysiology
Capillary electrophoresis
Clamping devices
Neurons
Mass spectrometry

Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

Kumar, R., Zhao, S., Vetting, M. W., Wood, B. M. K., Sakai, A., Cho, K., Solbiati, J., Almo, S. C., Sweedler, J. V., Jacobson, M. P., Gerlt, J. A. & Cronan, J. E., Feb 11 2014, In : mBio. 5, 1, e00933-13.

Research output: Contribution to journalArticle

Betaine
Paracoccus denitrificans
Metabolomics
Hydroxyproline
Rhodobacter sphaeroides

Publish only your original research

Sweedler, J. V., Apr 1 2014, In : Analytical chemistry. 86, 7, 1 p.

Research output: Contribution to journalEditorial

Small-Volume Analysis of Cell-Cell Signaling Molecules in the Brain

Romanova, E. V., Aerts, J. T., Croushore, C. A. & Sweedler, J. V., Jan 1 2014, In : Neuropsychopharmacology. 39, 1, p. 50-64 15 p.

Research output: Contribution to journalReview article

Cell Size
Brain
Research
Nervous System
Technology

So you want to be a principal investigator?

Sweedler, J. V., Aug 5 2014, In : Analytical chemistry. 86, 15, 1 p.

Research output: Contribution to journalEditorial

Spatial organization of pseudomonas aeruginosa biofilms probed by combined matrix-assisted laser desorption ionization mass spectrometry and confocal raman microscopy

Masyuko, R. N., Lanni, E. J., Driscoll, C. M., Shrout, J. D., Sweedler, J. V. & Bohn, P. W., Oct 15 2014, In : Analyst. 139, 22, p. 5700-5708 9 p.

Research output: Contribution to journalArticle

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Biofilms
Confocal Microscopy
Pseudomonas aeruginosa
Ionization

The analytical chemistry advisory boards

Sweedler, J. V., Jul 1 2014, In : Analytical chemistry. 86, 13, 1 p.

Research output: Contribution to journalEditorial

Chemical analysis

The ctenophore genome and the evolutionary origins of neural systems

Moroz, L. L., Kocot, K. M., Citarella, M. R., Dosung, S., Norekian, T. P., Povolotskaya, I. S., Grigorenko, A. P., Dailey, C., Berezikov, E., Buckley, K. M., Ptitsyn, A., Reshetov, D., Mukherjee, K., Moroz, T. P., Bobkova, Y., Yu, F., Kapitonov, V. V., Jurka, J., Bobkov, Y. V., Swore, J. J. & 16 others, Girardo, D. O., Fodor, A., Gusev, F., Sanford, R., Bruders, R., Kittler, E., Mills, C. E., Rast, J. P., Derelle, R., Solovyev, V. V., Kondrashov, F. A., Swalla, B. J., Sweedler, J. V., Rogaev, E. I., Halanych, K. M. & Kohn, A. B., Jan 1 2014, In : Nature. 510, 7503, p. 109-114 6 p.

Research output: Contribution to journalArticle

Ctenophora
Genome
Genes
Ribes
Developmental Genes

The Past, Present, and Future of Analytical Chemistry According to Chris Enke

Sweedler, J. V., Oct 7 2014, In : Analytical chemistry. 86, 19, 1 p.

Research output: Contribution to journalEditorial

Chemical analysis

Too busy to review?

Sweedler, J. V., Jun 3 2014, In : Analytical chemistry. 86, 11, 1 p.

Research output: Contribution to journalEditorial

Understanding the impact of fractionation and dynamic exclusion on proteomics

Zavala, C., Nixon, S., Southey, B. R., Wu, C., Romanova, E. V., Sweedler, J. V. & Rodriguez-Zas, S. L., Jan 1 2014, Proceedings of the 6th International Conference on Bioinformatics and Computational Biology, BICOB 2014. International Society for Computers and Their Applications, p. 93-96 4 p. (Proceedings of the 6th International Conference on Bioinformatics and Computational Biology, BICOB 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fractionation
Proteomics
Proteins
Peptides
Databases

Writing a review

Sweedler, J. V., Oct 16 2014, In : Analytical chemistry. 86, 21, 1 p.

Research output: Contribution to journalEditorial