TY - GEN
T1 - 3D laser optoacoustic ultrasonic imaging system for preclinical research
AU - Ermilov, Sergey A.
AU - Conjusteau, Andre
AU - Hernandez, Travis
AU - Su, Richard
AU - Nadvoretskiy, Vyacheslav
AU - Tsyboulski, Dmitri
AU - Anis, Fatima
AU - Anastasio, Mark A.
AU - Oraevsky, Alexander A.
PY - 2013/5/28
Y1 - 2013/5/28
N2 - In this work, we introduce a novel three-dimensional imaging system for in vivo high-resolution anatomical and functional whole-body visualization of small animal models developed for preclinical or other type of biomedical research. The system (LOUIS-3DM) combines a multi-wavelength optoacoustic and ultrawide-band laser ultrasound tomographies to obtain coregistered maps of tissue optical absorption and acoustic properties, displayed within the skin outline of the studied animal. The most promising applications of the LOUIS-3DM include 3D angiography, cancer research, and longitudinal studies of biological distribution of optoacoustic contrast agents (carbon nanotubes, metal plasmonic nanoparticles, etc.).
AB - In this work, we introduce a novel three-dimensional imaging system for in vivo high-resolution anatomical and functional whole-body visualization of small animal models developed for preclinical or other type of biomedical research. The system (LOUIS-3DM) combines a multi-wavelength optoacoustic and ultrawide-band laser ultrasound tomographies to obtain coregistered maps of tissue optical absorption and acoustic properties, displayed within the skin outline of the studied animal. The most promising applications of the LOUIS-3DM include 3D angiography, cancer research, and longitudinal studies of biological distribution of optoacoustic contrast agents (carbon nanotubes, metal plasmonic nanoparticles, etc.).
KW - laser ultrasound
KW - Photoacoustic tomography
KW - speed of sound tomography
UR - http://www.scopus.com/inward/record.url?scp=84878028506&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878028506&partnerID=8YFLogxK
U2 - 10.1117/12.2008811
DO - 10.1117/12.2008811
M3 - Conference contribution
AN - SCOPUS:84878028506
SN - 9780819493507
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Photons Plus Ultrasound
T2 - Photons Plus Ultrasound: Imaging and Sensing 2013
Y2 - 3 February 2013 through 5 February 2013
ER -