3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

David B. Kolesky, Ryan L. Truby, A. Sydney Gladman, Travis A. Busbee, Kimberly A. Homan, Jennifer A. Lewis

Research output: Contribution to journalArticle


A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.

Original languageEnglish (US)
Pages (from-to)3124-3130
Number of pages7
JournalAdvanced Materials
Issue number19
StatePublished - May 21 2014


  • 3D printing
  • biomaterials
  • bioprinting
  • tissue engineering
  • vasculature

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Kolesky, D. B., Truby, R. L., Gladman, A. S., Busbee, T. A., Homan, K. A., & Lewis, J. A. (2014). 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs. Advanced Materials, 26(19), 3124-3130. https://doi.org/10.1002/adma.201305506