@inproceedings{50970f90ebf04964b6fe65f6872b7035,
title = "2SNV: Quasispecies reconstruction from PacBio reads",
abstract = "Pacific Biosciences (PacBio) sequencing is providing thousands of reads with the length up to 10,000 bases. In most cases this length is enough to cover entire region of interest however this technology has high (≈15%) error rate. We propose a method for viral haplotype reconstruction using long SMRT reads. The proposed method based on correlation between SNVs and maximum likelihood for frequency estimation. When applied to PacBio reads from an Influenza A Virus (IAV) sample with ten variants, our method was able to reconstruct the nine most frequent.",
keywords = "PacBio, SNV, viral quasispecies",
author = "Alexander Artyomenko and Wu, {Nicholas C.} and Serghei Mangul and Eleazar Eskin and Ren Sun and Alex Zelikovsky",
note = "Publisher Copyright: {\textcopyright} 2015 IEEE.; 5th IEEE International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2015 ; Conference date: 15-10-2015 Through 17-10-2015",
year = "2015",
month = dec,
day = "2",
doi = "10.1109/ICCABS.2015.7344730",
language = "English (US)",
series = "2015 IEEE 5th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2015",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
booktitle = "2015 IEEE 5th International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2015",
address = "United States",
}