(2aS,3S,6S,7S,7bR)-7-[(Dimethylphenyl) -silyl]-2-oxo-6- [(1R,2S)- 2-phenylcyclohexyloxy]-2a,3,6,7,7a,7b -hexahydro-2H-1,4,5- trioxa-4 a-azacyclopenta[cd]indene-3-carboxylic acid 1-methylethyl ester

Atli Thorarensen, Kevin A. Swiss, Scott E. Denmark

Research output: Contribution to journalArticle

Abstract

The structure of the title compound, C 31 H 39 NO 7 Si, was determined and found to be a fused tricyclic nitroso acetal. Remarkable features include a twist-boat conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σ(angles) = 310.6(6)°]. Three of the contiguous stereocenters in the nitroso acetal are of the same correct relative and absolute configuration as is found in (+)-crotanecine.

Original languageEnglish (US)
Pages (from-to)[d]2558-2561
JournalActa Crystallographica, Section C: Crystal Structure Communications
Volume52
Issue numberpt 10
DOIs
StatePublished - Jan 1 1996

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Acetals
Carboxylic Acids
Esters
Oxazines
Ships
Boats
Conformations
Atoms
indene
oxazine 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

@article{576599af8790475e921ec995468e38d5,
title = "(2aS,3S,6S,7S,7bR)-7-[(Dimethylphenyl) -silyl]-2-oxo-6- [(1R,2S)- 2-phenylcyclohexyloxy]-2a,3,6,7,7a,7b -hexahydro-2H-1,4,5- trioxa-4 a-azacyclopenta[cd]indene-3-carboxylic acid 1-methylethyl ester",
abstract = "The structure of the title compound, C 31 H 39 NO 7 Si, was determined and found to be a fused tricyclic nitroso acetal. Remarkable features include a twist-boat conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σ(angles) = 310.6(6)°]. Three of the contiguous stereocenters in the nitroso acetal are of the same correct relative and absolute configuration as is found in (+)-crotanecine.",
author = "Atli Thorarensen and Swiss, {Kevin A.} and Denmark, {Scott E.}",
year = "1996",
month = "1",
day = "1",
doi = "10.1107/S0108270196005434",
language = "English (US)",
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pages = "[d]2558--2561",
journal = "Acta Crystallographica, Section C: Crystal Structure Communications",
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number = "pt 10",

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TY - JOUR

T1 - (2aS,3S,6S,7S,7bR)-7-[(Dimethylphenyl) -silyl]-2-oxo-6- [(1R,2S)- 2-phenylcyclohexyloxy]-2a,3,6,7,7a,7b -hexahydro-2H-1,4,5- trioxa-4 a-azacyclopenta[cd]indene-3-carboxylic acid 1-methylethyl ester

AU - Thorarensen, Atli

AU - Swiss, Kevin A.

AU - Denmark, Scott E.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - The structure of the title compound, C 31 H 39 NO 7 Si, was determined and found to be a fused tricyclic nitroso acetal. Remarkable features include a twist-boat conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σ(angles) = 310.6(6)°]. Three of the contiguous stereocenters in the nitroso acetal are of the same correct relative and absolute configuration as is found in (+)-crotanecine.

AB - The structure of the title compound, C 31 H 39 NO 7 Si, was determined and found to be a fused tricyclic nitroso acetal. Remarkable features include a twist-boat conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σ(angles) = 310.6(6)°]. Three of the contiguous stereocenters in the nitroso acetal are of the same correct relative and absolute configuration as is found in (+)-crotanecine.

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