2.45 - The Aging Central Auditory System

Kendra D. Maclaine, Daniel A. Llano

Research output: Chapter in Book/Report/Conference proceedingChapter


Aging-related hearing loss occurs in the auditory periphery and in the central auditory system. Two major changes are seen. First, there is a general loss of the ability of central auditory neurons to encode the fine temporal components of acoustic signals. Second, there is a downregulation of the enzymatic machinery that produces the inhibitory neurotransmitters, GABA and glycine. These two phenomena of central auditory processing and are likely related.

Original languageEnglish (US)
Title of host publicationThe Senses
Subtitle of host publicationA Comprehensive Reference: Volume 1-7, Second Edition
Number of pages12
ISBN (Electronic)9780128054093
ISBN (Print)9780128054086
StatePublished - Jan 1 2020


  • Aging
  • Auditory
  • Hearing loss
  • Inhibition
  • Synapse

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience


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