1-methyl-1-vinyl- and 1-methyl-1-(prop-2-enyl)silacyclobutane: Reagents for palladium-catalyzed cross-coupling reactions of aryl halides

Scott E. Denmark, Zhigang Wang

Research output: Contribution to journalArticle

Abstract

1-Methyl-1-vinylsilacyclobutane (1) and 1-methyl-1(prop-2- enyl)silacyclobutane (2) undergo rapid and high yielding cross-coupling with aromatic halides. Many different substituents and patterns on the aromatic moiety are tolerated. All reactions can be run at room temperature and require the presence of tetrabutylammonium fluoride and Pd(dba)2. Both silacyclobutanes can be made in one step from commercially available precursors.

Original languageEnglish (US)
Pages (from-to)999-1003
Number of pages5
JournalSynthesis
Issue number7
DOIs
StatePublished - Jan 1 2000

Keywords

  • Alkenes
  • Cross-coupling
  • Organosilicon
  • Palladium catalysis
  • Styrenes

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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