1α,25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C,D-ring side-chain

Gary H. Posner; M. Christina White; Patrick Dolan; Thomas W. Kensler; Shigefumi Yukihiro; Sandra E. Guggino

doi:10.1016/S0960-894X(01)80840-4

1α,25-dihydroxyvitamin D₃ hybrid analogs with structural changes at both the A-ring and the C,D-ring side-chain

Gary H. Posner
, M. Christina White
, Patrick Dolan
, Thomas W. Kensler
, Shigefumi Yukihiro
, Sandra E. Guggino

Research output: Contribution to journal › Article › peer-review

Abstract

Calcitrol analogs 5, designed to combine two remote structural changes each of which separately produces a sharply different biological profile, have biological activities that are a blending of the effects of each structural change.

Original language	English (US)
Pages (from-to)	2919-2924
Number of pages	6
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	4
Issue number	24
DOIs	https://doi.org/10.1016/S0960-894X(01)80840-4
State	Published - Dec 22 1994
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Online availability

10.1016/S0960-894X(01)80840-4

Library availability

Discover UIUC Full Text

Cite this

@article{7802dd09e95e4bb98b888f934a35eed1,

title = "1α,25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C,D-ring side-chain",

abstract = "Calcitrol analogs 5, designed to combine two remote structural changes each of which separately produces a sharply different biological profile, have biological activities that are a blending of the effects of each structural change.",

author = "Posner, \{Gary H.\} and White, \{M. Christina\} and Patrick Dolan and Kensler, \{Thomas W.\} and Shigefumi Yukihiro and Guggino, \{Sandra E.\}",

year = "1994",

month = dec,

day = "22",

doi = "10.1016/S0960-894X(01)80840-4",

language = "English (US)",

volume = "4",

pages = "2919--2924",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

number = "24",

}

TY - JOUR

T1 - 1α,25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C,D-ring side-chain

AU - Posner, Gary H.

AU - White, M. Christina

AU - Dolan, Patrick

AU - Kensler, Thomas W.

AU - Yukihiro, Shigefumi

AU - Guggino, Sandra E.

PY - 1994/12/22

Y1 - 1994/12/22

N2 - Calcitrol analogs 5, designed to combine two remote structural changes each of which separately produces a sharply different biological profile, have biological activities that are a blending of the effects of each structural change.

AB - Calcitrol analogs 5, designed to combine two remote structural changes each of which separately produces a sharply different biological profile, have biological activities that are a blending of the effects of each structural change.

UR - https://www.scopus.com/pages/publications/0028587852

UR - https://www.scopus.com/pages/publications/0028587852#tab=citedBy

U2 - 10.1016/S0960-894X(01)80840-4

DO - 10.1016/S0960-894X(01)80840-4

M3 - Article

AN - SCOPUS:0028587852

SN - 0960-894X

VL - 4

SP - 2919

EP - 2924

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 24

ER -