α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

Ann S. Clark; Bruce Nock; Harvey H. Feder; Edward J. Roy

doi:10.1016/0006-8993(85)90028-9

α₁-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

Ann S. Clark, Bruce Nock, Harvey H. Feder, Edward J. Roy

Research output: Contribution to journal › Article › peer-review

Abstract

Prazosin, a putative α₁-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.

Original language	English (US)
Pages (from-to)	197-199
Number of pages	3
Journal	Brain Research
Volume	330
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(85)90028-9
State	Published - Mar 18 1985

Keywords

estrogen receptors
norepinephrine
progestin receptors

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

Access to Document

10.1016/0006-8993(85)90028-9

Cite this

@article{94194b528a3f4f1d9af5913f74dcec54,

title = "α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area",

abstract = "Prazosin, a putative α1-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.",

keywords = "estrogen receptors, norepinephrine, progestin receptors",

author = "Clark, {Ann S.} and Bruce Nock and Feder, {Harvey H.} and Roy, {Edward J.}",

note = "Funding Information: 04467, NIMH-29006 and a grant from the Busch FoundationR, utgersU niversity( all to H.H.F.). We thank Diane Lynn and Marlene Wilson for technical assistanceP. razosinwas a generousg ift of E. M.",

year = "1985",

month = mar,

day = "18",

doi = "10.1016/0006-8993(85)90028-9",

language = "English (US)",

volume = "330",

pages = "197--199",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

AU - Clark, Ann S.

AU - Nock, Bruce

AU - Feder, Harvey H.

AU - Roy, Edward J.

N1 - Funding Information: 04467, NIMH-29006 and a grant from the Busch FoundationR, utgersU niversity( all to H.H.F.). We thank Diane Lynn and Marlene Wilson for technical assistanceP. razosinwas a generousg ift of E. M.

PY - 1985/3/18

Y1 - 1985/3/18

N2 - Prazosin, a putative α1-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.

AB - Prazosin, a putative α1-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.

KW - estrogen receptors

KW - norepinephrine

KW - progestin receptors

UR - http://www.scopus.com/inward/record.url?scp=0021943641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021943641&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(85)90028-9

DO - 10.1016/0006-8993(85)90028-9

M3 - Article

C2 - 2985191

AN - SCOPUS:0021943641

VL - 330

SP - 197

EP - 199

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1

ER -