α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

Ann S. Clark; Bruce Nock; Harvey H. Feder; Edward J. Roy

doi:10.1016/0006-8993(85)90028-9

α₁-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area

Ann S. Clark, Bruce Nock, Harvey H. Feder, Edward J. Roy

Research output: Contribution to journal › Article › peer-review

Abstract

Prazosin, a putative α₁-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.

Original language	English (US)
Pages (from-to)	197-199
Number of pages	3
Journal	Brain Research
Volume	330
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(85)90028-9
State	Published - Mar 18 1985

Keywords

estrogen receptors
norepinephrine
progestin receptors

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

Online availability

10.1016/0006-8993(85)90028-9

Library availability

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Cite this

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title = "α1-noradrenergic receptor blockade decreases nuclear estrogen receptor binding in guinea pig hypothalamus and preoptic area",

abstract = "Prazosin, a putative α1-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.",

keywords = "estrogen receptors, norepinephrine, progestin receptors",

author = "Clark, {Ann S.} and Bruce Nock and Feder, {Harvey H.} and Roy, {Edward J.}",

note = "Funding Information: 04467, NIMH-29006 and a grant from the Busch FoundationR, utgersU niversity( all to H.H.F.). We thank Diane Lynn and Marlene Wilson for technical assistanceP. razosinwas a generousg ift of E. M.",

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doi = "10.1016/0006-8993(85)90028-9",

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AU - Clark, Ann S.

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AU - Feder, Harvey H.

AU - Roy, Edward J.

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AB - Prazosin, a putative α1-noradrenergic antagonist, reduced nuclear estrogen receptor levels in the hypothalamus and preoptic area of the estrogen-primed guinea pig. Noradrenergic transmission may alter steroid-dependent processes and neuroendocrine function through actions on steroid-concentrating cells.

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KW - norepinephrine

KW - progestin receptors

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