Zeynep Madak Erdogan

Associate Dean, Graduate College

Sylvia D. Stroup Scholar, Food Science and Human Nutrition
Associate Professor, Food Science and Human Nutrition
Associate Professor, Nutritional Sciences
Associate Professor, Biomedical and Translational Sciences
Associate Professor, Carl R. Woese Institute for Genomic Biology
Affiliate, Personalized Nutrition Initiative, Carl R. Woese Institute for Genomic Biology
Associate Professor, National Center for Supercomputing Applications (NCSA)
Associate Professor, Center for Digital Agriculture, National Center for Supercomputing Applications (NCSA)
Associate Director for Education, Cancer Center at Illinois, Office of the Vice Chancellor for Research and Innovation

https://orcid.org/0000-0003-2607-1643

Emailzmadake2illinoisedu

55 Article
11 Review article
2 Editorial
1 Conference contribution
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1 - 50 out of 72 results

2024
Comparative hepatotoxicity of novel lithium bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) and legacy Perfluorooctanoic acid (PFOA) in male mice: Insights into epigenetic mechanisms and pathway-specific responses
Sands, M., Zhang, X., gal, A., Laws, M., Spinella, M., Erdogan, Z. M. & Irudayaraj, J., Mar 2024, In: Environment international. 185, 108556.
Research output: Contribution to journal › Article › peer-review

Open Access
From Fundamentals to the Clinic: Advancing Obesity Research in Endocrinology
Madak-Erdogan, Z., Hammes, S. R. & Furkan Burak, M., Jun 2024, In: Journal of the Endocrine Society. 8, 6
Research output: Contribution to journal › Editorial › peer-review

Open Access
Navigating nonalcoholic fatty liver disease (NAFLD): Exploring the roles of estrogens, pharmacological and medical interventions, and life style
Zuo, Q., Park, N. H., Lee, J. K., Santaliz-Casiano, A. & Madak-Erdogan, Z., Mar 2024, In: Steroids. 203, 109330.
Research output: Contribution to journal › Article › peer-review
Perfluorooctanesulfonic Acid Alters Pro-Cancer Phenotypes and Metabolic and Transcriptional Signatures in Testicular Germ Cell Tumors
Boyd, R. I., Shokry, D., Fazal, Z., Rennels, B. C., Freemantle, S. J., La Frano, M. R., Prins, G. S., Madak Erdogan, Z., Irudayaraj, J., Singh, R. & Spinella, M. J., Apr 2024, In: Toxics. 12, 4, 232.
Research output: Contribution to journal › Article › peer-review

Open Access
PFAS and their association with the increased risk of cardiovascular disease in postmenopausal women
Arredondo Eve, A., Tunc, E., Mehta, D., Yoo, J. Y., Yilmaz, H. E., Emren, S. V., Akçay, F. A. & Madak Erdogan, Z., Aug 1 2024, In: Toxicological Sciences. 200, 2, p. 312-323 12 p., kfae065.
Research output: Contribution to journal › Article › peer-review
Targeting NAD+ metabolism: Pre-clinical insights into potential cancer therapy strategies
Mogol, A. N., Kaminsky, A. Z., Dutton, D. J. & Madak Erdogan, Z., May 1 2024, In: Endocrinology. 165, 5, bqae043.
Research output: Contribution to journal › Article › peer-review
Targeting systemic and gut microbial metabolism in ER⁺ breast cancer
Heath, H., Mogol, A. N., Santaliz Casiano, A., Zuo, Q. & Madak-Erdogan, Z., Apr 2024, In: Trends in Endocrinology and Metabolism. 35, 4, p. 321-330 10 p.
Research output: Contribution to journal › Review article › peer-review
The effect of exposure to neighborhood violence on Glucocorticoid Receptor signaling in lung tumors
Heath, H., Yoo, J. Y., Akter, S., Jain, A., Sharma, V., McGee, H., Soliman, A., Mahmoud, A. M., Matthews, A. K., Winn, R. A., Madak-Erdogan, Z. & Kim, S. J., Jul 2024, In: Cancer Research Communications. 4, 7, p. 1643-1654 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2023
Identification of metabolic pathways contributing to ER⁺ breast cancer disparities using a machine-learning pipeline
Santaliz-Casiano, A., Mehta, D., Danciu, O. C., Patel, H., Banks, L., Zaidi, A., Buckley, J., Rauscher, G. H., Schulte, L., Weller, L. R., Taiym, D., Liko-Hazizi, E., Pulliam, N., Friedewald, S. M., Khan, S., Kim, J. J., Gradishar, W., Hegerty, S., Frasor, J. & Hoskins, K. F. & 1 others, Madak-Erdogan, Z., Dec 2023, In: Scientific reports. 13, 1, 12136.
Research output: Contribution to journal › Article › peer-review

Open Access
NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
Mogol, A. N., Zuo, Q., Yoo, J. Y., Kaminsky, A. Z., Imir, O. B., Landesman, Y., Walker, C. J. & Madak erdogan, Z., Jun 1 2023, In: Endocrinology. 164, 6, bqad073.
Research output: Contribution to journal › Article › peer-review
2022
Adherence to a priori-Defined Diet Quality Indices Throughout the Early Disease Course Is Associated With Survival in Head and Neck Cancer Survivors: An Application Involving Marginal Structural Models
Maino Vieytes, C. A., Rodriguez-Zas, S. L., Madak-Erdogan, Z., Smith, R. L., Zarins, K. R., Wolf, G. T., Rozek, L. S., Mondul, A. M. & Arthur , A. E., Apr 25 2022, In: Frontiers in Nutrition. 9, 791141.
Research output: Contribution to journal › Article › peer-review

Open Access
Endocrine-Disrupting Chemicals and Breast Cancer: Disparities in Exposure and Importance of Research Inclusivity
Santaliz Casiano, A., Lee, A., Teteh, D., Madak Erdogan, Z. & Treviño, L., May 1 2022, In: Endocrinology (United States). 163, 5, bqac034.
Research output: Contribution to journal › Review article › peer-review

Open Access
Expanding Our Scope and Our Identity
Erdogan, Z. M. & Hammes, S. R., Nov 1 2022, In: Journal of the Endocrine Society. 6, 11, bvac149.
Research output: Contribution to journal › Editorial › peer-review

Open Access
Liver Metastatic Breast Cancer: Epidemiology, Dietary Interventions, and Related Metabolism
Zuo, Q., Park, N. H., Lee, J. K. & Madak Erdogan, Z., Jun 2022, In: Nutrients. 14, 12, 2376.
Research output: Contribution to journal › Review article › peer-review

Open Access
Per- and polyfluoroalkyl substances target and alter human prostate stem-progenitor cells
Hu, W. Y., Lu, R., Hu, D. P., Imir, O. B., Zuo, Q., Moline, D., Afradiasbagharani, P., Liu, L., Lowe, S., Birch, L., Griend, D. J. V., Madak-Erdogan, Z. & Prins, G. S., Mar 2022, In: Biochemical Pharmacology. 197, 114902.
Research output: Contribution to journal › Article › peer-review

Open Access
Sex Differences Across the Life Course: A Focus On Unique Nutritional and Health Considerations among Women
Bailey, R. L., Dog, T. L., Smith-Ryan, A. E., Das, S. K., Baker, F. C., Madak-Erdogan, Z., Hammond, B. R., Sesso, H. D., Eapen, A., Mitmesser, S. H., Wong, A. & Nguyen, H., Jul 1 2022, In: Journal of Nutrition. 152, 7, p. 1597-1610 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Spatial Analysis of Tumor Heterogeneity Using Machine Learning Techniques
Mitra, C., Yoo, J. Y., Madak-Erdogan, Z. & Soliman, A., 2022, Proceedings - 2022 IEEE 19th International Conference on Mobile Ad Hoc and Smart Systems, MASS 2022. Institute of Electrical and Electronics Engineers Inc., p. 781-786 6 p. (Proceedings - 2022 IEEE 19th International Conference on Mobile Ad Hoc and Smart Systems, MASS 2022).
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Targeting Metabolic Adaptations in the Breast Cancer–Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy
Zuo, Q., Mogol, A. N., Liu, Y. J., Casiano, A. S., Chien, C., Drnevich, J., Imir, O. B., Kulkoyluoglu-Cotul, E., Park, N. H., Shapiro, D. J., Park, B. H., Ziegler, Y., Katzenellenbogen, B. S., Aranda, E., O’Neill, J. D., Raghavendra, A. S., Tripathy, D. & Erdogan, Z. M., Jun 2022, In: Molecular Cancer Research. 20, 6, p. 923-937 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer
Nelczyk, A. T., Ma, L., Gupta, A. D., Gamage, H. E. V., McHenry, M. T., Henn, M. A., Kadiri, M., Wang, Y., Krawczynska, N., Bendre, S., He, S., Shahoei, S. H., Madak-Erdogan, Z., Hsiao, S. H., Saleh, T., Carpenter, V., Gewirtz, D. A., Spinella, M. J. & Nelson, E. R., Nov 1 2022, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1868, 11, 166515.
Research output: Contribution to journal › Article › peer-review

Open Access
Toward a Mechanistic Understanding of Poly-and Perfluoroalkylated Substances and Cancer
Boyd, R. I., Ahmad, S., Singh, R., Fazal, Z., Prins, G. S., Erdogan, Z. M., Irudayaraj, J. & Spinella, M. J., Jun 1 2022, In: Cancers. 14, 12, 2919.
Research output: Contribution to journal › Review article › peer-review

Open Access
2021
Identification of Circulating Diagnostic Biomarkers for Coronary Microvascular Disease in Postmenopausal Women Using Machine-Learning Techniques
Arredondo Eve, A., Tunc, E., Liu, Y.-J., Agrawal, S., Erbak Yilmaz, H., Emren, S. V., Akyıldız Akçay, F., Mainzer, L., Žurauskienė, J. & Madak Erdogan, Z., May 2021, In: Metabolites. 11, 6, 339.
Research output: Contribution to journal › Article › peer-review

Open Access
Making an IMPACT on Career Development for Early- And Mid-career Faculty
Sikora, M. J., Riggins, R. B. & Madak-Erdogan, Z., Mar 1 2021, In: Endocrinology (United States). 162, 3, bqaa247.
Research output: Contribution to journal › Article › peer-review

Open Access
Obesity and Postmenopausal Hormone Receptor-positive Breast Cancer: Epidemiology and Mechanisms
Zuo, Q., Band, S., Kesavadas, M. & Madak Erdogan, Z., Dec 1 2021, In: Endocrinology (United States). 162, 12, bqab195.
Research output: Contribution to journal › Review article › peer-review

Open Access
Pathway preferential estrogens prevent hepatosteatosis due to ovariectomy and high−fat diets
Zuo, Q., Chen, K. L., Eve, A. A., Liu, Y. J., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Madak-Erdogan, Z., Oct 2021, In: Nutrients. 13, 10, 3334.
Research output: Contribution to journal › Article › peer-review

Open Access
Per- and Polyfluoroalkyl Substance Exposure Combined with High-Fat Diet Supports Prostate Cancer Progression
Imir, O. B., Kaminsky, A. Z., Zuo, Q.-Y., Liu, Y.-J., Singh, R., Spinella, M. J., Irudayaraj, J., Hu, W.-Y., Prins, G. S. & Madak Erdogan, Z., Nov 2021, In: Nutrients. 13, 11, 3902.
Research output: Contribution to journal › Article › peer-review

Open Access
Racial Differences in Lifestyle, Demographic, and Health Factors Associated with Quality of Life (QoL) in Midlife Women
Smith, B. P., Cardoso-Mendoza, E., Flaws, J. A., Madak-Erdogan, Z. & Smith, R. L., Jan 6 2021, In: Women's midlife health. 7, 1, p. 2
Research output: Contribution to journal › Article › peer-review

Open Access
Steroid Hormones and Receptors in Health and Disease: A Research Conference Co-Organized by FASEB and the International Committee on Rapid Responses to Steroid Hormones (RRSH), May 25-27, 2021
Barton, M., Frigo, D. E., Madak-Erdogan, Z., Mauvais-Jarvis, F. & Prossnitz, E. R., Nov 2021, In: FASEB Journal. 35, 11, e21858.
Research output: Contribution to journal › Article › peer-review

Open Access
The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression
Baek, A. E., Krawczynska, N., Das Gupta, A., Dvoretskiy, S. V., You, S., Park, J., Deng, Y.-H., Sorrells, J. E., Smith, B. P., Ma, L., Nelson, A. T., McDowell, H. B., Sprenger, A., Henn, M. A., Madak-Erdogan, Z., Kong, H., Boppart, S. A., Boppart, M. D. & Nelson, E. R., Jul 1 2021, In: Endocrinology. 162, 7, bqab095.
Research output: Contribution to journal › Article › peer-review
2020
A Computational Statistics Approach to Evaluate Blood Biomarkers for Breast Cancer Risk Stratification
Oktay, K., Santaliz-Casiano, A., Patel, M., Marino, N., Storniolo, A. M. V., Torun, H., Acar, B. & Madak Erdogan, Z., Feb 1 2020, In: Hormones and Cancer. 11, 1, p. 17-33 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Biomarkers of Broccoli Consumption: Implications for Glutathione Metabolism and Liver Health
Eve, A. A., Liu, X., Wang, Y., Miller, M. J., Jeffery, E. H. & Madak-Erdogan, Z., Sep 2020, In: Nutrients. 12, 9, p. 1-16 16 p., 2514.
Research output: Contribution to journal › Article › peer-review

Open Access
Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers
Cotul, E. K., Zuo, Q., Santaliz-Casiano, A., Imir, O. B., Mogol, A. N., Tunc, E., Duong, K., Lee, J. K., Ramesh, R., Odukoya, E., Kesavadas, M. P., Ziogaite, M., Smith, B. P., Mao, C., Shapiro, D. J., Park, B. H., Katzenellenbogen, B. S., Daly, D., Aranda, E. & O’neill, J. D. & 3 others, Walker, C., Landesman, Y. & Madak-Erdogan, Z., Sep 2020, In: Cancers. 12, 9, p. 1-22 22 p., 2397.
Research output: Contribution to journal › Article › peer-review

Open Access
Compounds which activate estrogen receptors and compositions and methods of using the same
Katzenellenbogen, J. A. (Inventor), Katzenellenbogen, B. (Inventor), Kim, S. H. (Inventor), Madak-Erdogan, Z. (Inventor) & Shaul, P. (Inventor), Jul 7 2020, U.S. Patent No. 10703698
Research output: Patent
Coronary Microvascular Dysfunction and Estrogen Receptor Signaling
Tunc, E., Eve, A. A. & Madak-Erdogan, Z., Mar 2020, In: Trends in Endocrinology and Metabolism. 31, 3, p. 228-238 11 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
Health disparities research is enabled by data diversity but requires much tighter integration of collaborative efforts
Cazier, J.-B., Mainzer, L. S., Ge, W., Žurauskienė, J. & Madak-Erdogan, Z., Dec 2020, In: Journal of Global Health. 10, 2, p. 1-4 4 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
Identification of early liver toxicity gene biomarkers using comparative supervised machine learning
Smith, B. P., Auvil, L. S., Welge, M. E., Bushell, C. B., Bhargava, R., Elango, N., Johnson, K. & Madak-Erdogan, Z., Dec 1 2020, In: Scientific reports. 10, 1, 19128.
Research output: Contribution to journal › Article › peer-review

Open Access
The window of vulnerability for uterus
Zuo, Q. & Erdogan, Z. M., 2020, In: Endocrinology (United States). 161, 8
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
2019
Combined Targeting of Estrogen Receptor Alpha and XPO1 Prevent Akt Activation, Remodel Metabolic Pathways and Induce Autophagy to Overcome Tamoxifen Resistance
Kulkoyluoglu-Cotul, E., Smith, B. P., Wrobel, K., Zhao, Y. C., Chen, K. L. A., Hieronymi, K., Imir, O. B., Duong, K., O’Callaghan, C., Mehta, A., Sahoo, S., Haley, B., Chang, H., Landesman, Y. & Madak-Erdogan, Z., Apr 4 2019, In: Cancers. 11, 4, 479.
Research output: Contribution to journal › Article › peer-review

Open Access
Crosstalk between Estrogen Signaling and Breast Cancer Metabolism
Kulkoyluoglu-Cotul, E., Arca, A. & Madak-Erdogan, Z., Jan 2019, In: Trends in Endocrinology and Metabolism. 30, 1, p. 25-38 14 p.
Research output: Contribution to journal › Review article › peer-review
Free fatty acids rewire cancer metabolism in obesity-associated breast cancer via estrogen receptor and mTOR signaling
Madak-Erdogan, Z., Band, S., Zhao, Y. C., Smith, B. P., Kulkoyluoglu-Cotul, E., Zuo, Q., Casiano, A. S., Wrobel, K., Rossi, G., Smith, R. L., Kim, S. H., Katzenellenbogen, J. A., Johnson, M. L., Patel, M., Marino, N., Storniolo, A. M. V. & Flaws11, J. A., 2019, In: Cancer Research. 79, 10, p. 2494-2510 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds
Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In: npj Breast Cancer. 5, 1, 45.
Research output: Contribution to journal › Article › peer-review

Open Access
2018
Estrogens and female liver health
Chen, K. L. & Madak-Erdogan, Z., May 2018, In: Steroids. 133, p. 38-43 6 p.
Research output: Contribution to journal › Article › peer-review
Long-Term Administration of Conjugated Estrogen and Bazedoxifene Decreased Murine Fecal β-Glucuronidase Activity Without Impacting Overall Microbiome Community
Chen, K. L. A., Liu, X., Zhao, Y. C., Hieronymi, K., Rossi, G., Auvil, L. S., Welge, M., Bushell, C., Smith, R. L., Carlson, K. E., Kim, S. H., Katzenellenbogen, J. A., Miller, M. J. & Madak-Erdogan, Z., Dec 1 2018, In: Scientific reports. 8, 1, 8166.
Research output: Contribution to journal › Article › peer-review

Open Access
Urban Neighborhood and Residential Factors Associated with Breast Cancer in African American Women: a Systematic Review
Smith, B. P. & Madak-Erdogan, Z., Apr 1 2018, In: Hormones and Cancer. 9, 2, p. 71-81 11 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
2017
Bazedoxifene and conjugated estrogen combination maintains metabolic homeostasis and benefits liver health
Chen, K. L. A., Zhao, Y. C., Hieronymi, K., Smith, B. P. & Madak-Erdogan, Z., Dec 2017, In: PloS one. 12, 12, Y.
Research output: Contribution to journal › Article › peer-review

Open Access
Impact of Diet and Nutrition on Cancer Hallmarks
Chen, K. L., Jung, P., Kulkoyluoglu-Cotul, E., Liguori, C., Lumibao, J., Mazewski, C., Ranard, K., Rowles, J. L., Wang, Y., Xue, L. & Madak-Erdogan, Z., 2017, In: Journal of cancer prevention & current research. 7, 4
Research output: Contribution to journal › Article › peer-review

Open Access
2016
Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues
Madak-Erdogan, Z., Kim, S. H., Gong, P., Zhao, Y. C., Zhang, H., Chambliss, K. L., Carlson, K. E., Mayne, C. G., Shaul, P. W., Korach, K. S., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., May 24 2016, In: Science Signaling. 9, 429, ra53.
Research output: Contribution to journal › Article › peer-review

Open Access
Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland
Madak-Erdogan, Z., Gong, P., Zhao, Y. C., Xu, L., Wrobel, K. U., Hartman, J. A., Wang, M., Cam, A., Iwaniec, U. T., Turner, R. T., Twaddle, N. C., Doerge, D. R., Khan, I. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Helferich, W. G., Feb 1 2016, In: Molecular Nutrition and Food Research. 60, 2, p. 369-380 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Differential utilization of nuclear and extranuclear receptor signaling pathways in the actions of estrogens, SERMs, and a tissue-selective estrogen complex (TSEC)
Madak-Erdogan, Z., Gong, P. & Katzenellenbogen, B. S., Apr 1 2016, In: Journal of Steroid Biochemistry and Molecular Biology. 158, p. 198-206 9 p.
Research output: Contribution to journal › Article › peer-review
ERα-XPO1 cross talk controls tamoxifen sensitivity in tumors by altering ERK5 cellular localization
Wrobel, K., Zhao, Y. C., Kulkoyluoglu, E., Chen, K. L. A., Hieronymi, K., Holloway, J., Li, S., Ray, T., Ray, P. S., Landesman, Y., Lipka, A. E., Smith, R. L. & Madak-Erdogan, Z., Oct 2016, In: Molecular Endocrinology. 30, 10, p. 1029-1045 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Estrogen and Microbiota Crosstalk: Should We Pay Attention?
Chen, K. L. & Madak-Erdogan, Z., Nov 1 2016, In: Trends in Endocrinology and Metabolism. 27, 11, p. 752-755 4 p.
Research output: Contribution to journal › Short survey › peer-review

Zeynep Madak Erdogan

Research output

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