Research output per year
Research output per year
- 1 - 50 out of 82 results
Search results
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2022
A maternal low-protein diet during gestation induces hepatic autophagy-related gene expression in a sex-specific manner in Sprague-Dawley rats
Cai, M., Zhang, J., Chen, H. & Pan, Y-X., Aug 28 2022, In: British Journal of Nutrition. 128, 4, p. 592-603 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-wide cross-cancer analysis illustrates the critical role of bimodal miRNA in patient survival and drug responses to PI3K inhibitors
Moody, L., Xu, G. B., Pan, Y. X. & Chen, H., May 2022, In: PLoS computational biology. 18, 5, e1010109.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Caloric restriction following early-life high fat-diet feeding represses skeletal muscle TNF in male rats
Hernández-Saavedra, D., Moody, L., Tang, X., Goldberg, Z. J., Wang, A. P., Chen, H. & Pan, Y. X., May 2021, In: Journal of Nutritional Biochemistry. 91, 108598.Research output: Contribution to journal › Article › peer-review
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Maternal high-fat diet activates hepatic interleukin-4 in rat male offspring accompanied by increased eosinophil infiltration
Wang, H., Xu, G. B., Chen, H. & Pan, Y. X., Jan 2021, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 320, 1, p. G81-G92Research output: Contribution to journal › Article › peer-review
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Weight loss with exercise improves muscle architecture and progenitor cell populations compared with weight loss alone in mice with preneoplastic colorectal lesions
Roubos, S., D’souza, D., Hernández-Saavedra, D., Xu, G., Collao, N., Emmons, R., Larkin, J., Lloyd, J., Vanhie, J. J., Pan, Y. X., Chen, H. & De Lisio, M., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 7, p. 837-845 9 p.Research output: Contribution to journal › Article › peer-review
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2020
Considerations for feature selection using gene pairs and applications in large-scale dataset integration, novel oncogene discovery, and interpretable cancer screening
Moody, L., Chen, H. & Pan, Y. X., Oct 1 2020, In: BMC Medical Genomics. 13, 148.Research output: Contribution to journal › Article › peer-review
Open Access -
Epigenetic stratification of head and neck cancer survivors reveals differences in lycopene levels, alcohol consumption, and methylation of immune regulatory genes
Moody, L., Crowder, S. L., Fruge, A. D., Locher, J. L., Demark-Wahnefried, W., Rogers, L. Q., Delk-Licata, A., Carroll, W. R., Spencer, S. A., Black, M., Erdman, J. W., Chen, H., Pan, Y. X. & Arthur, A. E., Sep 11 2020, In: Clinical epigenetics. 12, 1, 138.Research output: Contribution to journal › Article › peer-review
Open Access -
Low-protein diet during gestation and lactation increases hepatic lipid accumulation through autophagy and histone deacetylase
Wang, H., Xu, G. B., Hernandez-Saavedra, D., Chen, H. & Pan, Y. X., Jul 2020, In: American Journal of Physiology - Endocrinology and Metabolism. 319, 1, p. E11-E25Research output: Contribution to journal › Article › peer-review
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Role of glucocorticoid signaling in exercise-associated changes in high-fat diet preference in rats
Yang, T. Y., Gardner, J. C., Gao, Z., Pan, Y. X. & Liang, N. C., Mar 1 2020, In: American journal of physiology. Regulatory, integrative and comparative physiology. 318, 3, p. R515-R528Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Choline supply during negative nutrient balance alters hepatic cystathionine β-synthase, intermediates of the methionine cycle and transsulfuration pathway, and liver function in Holstein cows
Coleman, D. N., Alharthi, A., Lopreiato, V., Trevisi, E., Miura, M., Pan, Y. X. & Loor, J. J., Sep 2019, In: Journal of Dairy Science. 102, 9, p. 8319-8331 13 p.Research output: Contribution to journal › Article › peer-review
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Computational methods to identify bimodal gene expression and facilitate personalized treatment in cancer patients
Moody, L., Mantha, S., Chen, H. & Pan, Y. X., Mar 2019, In: Journal of Biomedical Informatics: X. 1, 100001.Research output: Contribution to journal › Review article › peer-review
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Early-life programming of type 2 diabetes mellitus: Understanding the association between epigenetics/genetics and environmental factors
Kadayifci, F. Z., Haggard, S., Jeon, S., Ranard, K., Tao, D. & Pan, Y. X., 2019, In: Current Genomics. 20, 6, p. 453-463 11 p.Research output: Contribution to journal › Review article › peer-review
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Effects of obesity and exercise on colon cancer induction and hematopoiesis in mice
Emmons, R., Xu, G., Hernández-Saavedra, D., Kriska, A., Pan, Y. X., Chen, H. & De Lisio, M., Feb 1 2019, In: American Journal of Physiology - Endocrinology and Metabolism. 316, 2, p. E210-E220Research output: Contribution to journal › Article › peer-review
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Epigenetic regulation of carnitine palmitoyltransferase 1 (Cpt1a) by high fat diet
Moody, L., Xu, G. B., Chen, H. & Pan, Y. X., Feb 2019, In: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1862, 2, p. 141-152 12 p.Research output: Contribution to journal › Article › peer-review
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Epigenetic Regulation of Metabolism and Inflammation by Calorie Restriction
Hernández-Saavedra, D., Moody, L., Xu, G. B., Chen, H. & Pan, Y. X., May 1 2019, In: Advances in Nutrition. 10, 3, p. 520-536 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Hepatic 1-carbon metabolism enzyme activity, intermediate metabolites, and growth in neonatal Holstein dairy calves are altered by maternal supply of methionine during late pregnancy
Alharthi, A. S., Coleman, D. N., Liang, Y., Batistel, F., Elolimy, A. A., Yambao, R. C., Abdel-Hamied, E., Pan, Y. X., Parys, C., Alhidary, I. A., Abdelrahman, M. M. & Loor, J. J., Nov 2019, In: Journal of Dairy Science. 102, 11, p. 10291-10303 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Hepatic betaine-homocysteine methyltransferase and methionine synthase activity and intermediates of the methionine cycle are altered by choline supply during negative energy balance in Holstein cows
Coleman, D. N., Vailati-Riboni, M., Elolimy, A. A., Cardoso, F. C., Rodriguez-Zas, S. L., Miura, M., Pan, Y. X. & Loor, J. J., Sep 2019, In: Journal of Dairy Science. 102, 9, p. 8305-8318 14 p.Research output: Contribution to journal › Article › peer-review
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Maternal and Post-weaning High-Fat Diets Produce Distinct DNA Methylation Patterns in Hepatic Metabolic Pathways within Specific Genomic Contexts
Moody, L., Wang, H., Jung, P. M., Chen, H. & Pan, Y-X., Jun 30 2019, In: International Journal of Molecular Sciences. 20, 13, 3229.Research output: Contribution to journal › Article › peer-review
Open Access -
Maternal low-fat diet programs the hepatic epigenome despite exposure to an obesogenic postnatal diet
Moody, L., Shao, J., Chen, H. & Pan, Y. X., Sep 2019, In: Nutrients. 11, 9, 2075.Research output: Contribution to journal › Article › peer-review
Open Access -
Methionine Supply during Late-Gestation Triggers Offspring Sex-Specific Divergent Changes in Metabolic and Epigenetic Signatures in Bovine Placenta
Batistel, F., Alharthi, A. S., Yambao, R. R. C., Elolimy, A. A., Pan, Y. X., Parys, C. & Loor, J. J., Jan 1 2019, In: Journal of Nutrition. 149, 1, p. 6-17 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Perinatal High-Fat Diet and Bisphenol A: Effects on Behavior and Gene Expression in the Medial Prefrontal Cortex
Wise, L. M., Hernández-Saavedra, D., Boas, S. M., Pan, Y. X. & Juraska, J. M., Sep 1 2019, In: Developmental Neuroscience. 41, 1-2, p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Perinatal phthalate and high-fat diet exposure induce sex-specific changes in adipocyte size and DNA methylation
Moody, L., Kougias, D., Jung, P. M., Digan, I., Hong, A., Gorski, A., Chen, H., Juraska, J. & Pan, Y. X., Mar 2019, In: Journal of Nutritional Biochemistry. 65, p. 15-25 11 p.Research output: Contribution to journal › Article › peer-review
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The Efficacy of miR-20a as a Diagnostic and Prognostic Biomarker for Colorectal Cancer: A Systematic Review and Meta-Analysis
Moody, L., Dvoretskiy, S., An, R., Mantha, S. & Pan, Y-X., Aug 3 2019, In: Cancers. 11, 8, 1111.Research output: Contribution to journal › Review article › peer-review
Open Access -
Tissue-specific changes in Srebf1 and Srebf2 expression and DNA methylation with perinatal phthalate exposure
Moody, L., Hernández-Saavedra, D., Kougias, D. G., Chen, H., Juraska, J. M. & Pan, Y. X., Apr 1 2019, In: Environmental Epigenetics. 5, 2, dvz009.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Effects of perinatal exposure to phthalates and a high-fat diet on maternal behavior and pup development and social play
Kougias, D. G., Cortes, L. R., Moody, L., Rhoads, S., Pan, Y. X. & Juraska, J. M., Feb 2018, In: Endocrinology. 159, 2, p. 1088-1105 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
High-fat diet modifies expression of hepatic cellular senescence gene p16(INK4a) through chromatin modifications in adult male rats
Zhang, X., Xu, G. B., Zhou, D. & Pan, Y. X., Mar 14 2018, In: Genes and Nutrition. 13, 1, 6.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular mechanisms underlying the link between diet and DNA methylation
Kadayifci, F. Z., Zheng, S. & Pan, Y. X., Dec 14 2018, In: International journal of molecular sciences. 19, 12, 4055.Research output: Contribution to journal › Review article › peer-review
Open Access -
2017
Early-life nutritional programming of cognition-the fundamental role of epigenetic mechanisms in mediating the relation between early-life environment and learning and memory process
Moody, L., Chen, H. & Pan, Y. X., Mar 1 2017, In: Advances in Nutrition. 8, 2, p. 337-350 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Epigenetic regulation of centromere chromatin stability by dietary and environmental factors
Hernández-Saavedra, D., Strakovsky, R. S., Ostrosky-Wegman, P. & Pan, Y. X., Nov 1 2017, In: Advances in Nutrition. 8, 6, p. 889-904 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Methods and novel technology for microRNA quantification in colorectal cancer screening
Moody, L., He, H., Pan, Y. X. & Chen, H., 2017, In: Clinical epigenetics. 9, p. 119 1 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Placentome nutrient transporters and mammalian target of rapamycin signaling proteins are altered by the methionine supply during late gestation in dairy cows and are associated with newborn birth weight
Batistel, F., Alharthi, A. S. M., Wang, L., Parys, C., Pan, Y. X., Cardoso, F. C. & Loor, J. J., Sep 1 2017, In: Journal of Nutrition. 147, 9, p. 1640-1647 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Postnatal diet remodels hepatic DNA methylation in metabolic pathways established by a maternal high-fat diet
Moody, L., Chen, H. & Pan, Y. X., Nov 2017, In: Epigenomics. 9, 11, p. 1387-1402 16 p.Research output: Contribution to journal › Article › peer-review
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2016
Compensatory induction of Fads1 gene expression in heterozygous Fads2-null mice and by diet with a high n-6/n-3 PUFA ratio
Su, H., Zhou, D., Pan, Y. X., Wang, X. & Nakamura, M. T., 2016, In: Journal of Lipid Research. 57, 11, p. 1995-2004 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genistein exposure inhibits growth and alters steroidogenesis in adult mouse antral follicles
Patel, S., Peretz, J., Pan, Y. X., Helferich, W. G. & Flaws, J. A., Feb 15 2016, In: Toxicology and Applied Pharmacology. 293, p. 53-62 10 p.Research output: Contribution to journal › Article › peer-review
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2015
Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis
Strakovsky, R. S., Wang, H., Engeseth, N. J., Flaws, J. A., Helferich, W. G., Pan, Y. X. & Lezmi, S., Apr 5 2015, In: Toxicology and Applied Pharmacology. 284, 2, p. 101-112 12 p.Research output: Contribution to journal › Article › peer-review
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Early-life exposure to high-fat diet may predispose rats to gender-specific hepatic fat accumulation by programming Pepck expression
Zhou, D., Wang, H., Cui, H., Chen, H. & Pan, Y. X., May 1 2015, In: Journal of Nutritional Biochemistry. 26, 5, p. 433-440 8 p.Research output: Contribution to journal › Article › peer-review
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High-fat diet caused widespread epigenomic differences on hepatic methylome in rat
Zhang, Y., Wang, H., Zhou, D., Moody, L., Lezmi, S., Chen, H. & Pan, Y. X., Oct 1 2015, In: Physiological genomics. 47, 10, p. 514-523 10 p.Research output: Contribution to journal › Article › peer-review
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Induction of autophagy through the activating transcription factor 4 (ATF4)-dependent amino acid response pathway in maternal skeletal muscle may function as the molecular memory in response to gestational protein restriction to alert offspring to maternal nutrition
Wang, H., Wilson, G. J., Zhou, D., Lezmi, S., Chen, X., Layman, D. K. & Pan, Y. X., Aug 28 2015, In: British Journal of Nutrition. 114, 4, p. 519-532 14 p.Research output: Contribution to journal › Article › peer-review
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In utero growth restriction and catch-up adipogenesis after developmental di (2-ethylhexyl) phthalate exposure cause glucose intolerance in adult male rats following a high-fat dietary challenge
Strakovsky, R. S., Lezmi, S., Shkoda, I., Flaws, J. A., Helferich, W. G. & Pan, Y. X., Nov 2015, In: Journal of Nutritional Biochemistry. 26, 11, p. 1208-1220 13 p.Research output: Contribution to journal › Article › peer-review
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Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice
Liu, Y., Hilakivi-Clarke, L., Zhang, Y., Wang, X., Pan, Y. X., Xuan, J., Fleck, S. C., Doerge, D. R. & Helferich, W. G., Aug 1 2015, In: Molecular Nutrition and Food Research. 59, 8, p. 1419-1430 12 p.Research output: Contribution to journal › Article › peer-review
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Pathophysiological basis for compromised health beyond generations: Role of maternal high-fat diet and low-grade chronic inflammation
Zhou, D. & Pan, Y. X., 2015, In: Journal of Nutritional Biochemistry. 26, 1, p. 1-8 8 p.Research output: Contribution to journal › Review article › peer-review
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2014
Epigenetic mechanisms of colon cancer prevention: What can nutrition do?
Pan, Y. X., Zhang, Y. & Chen, H., Feb 1 2014, Molecular Mechanisms and Physiology of Disease: Implications for Epigenetics and Health. Springer, p. 401-426 26 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Genistein exposure during the early postnatal period favors the development of obesity in female, but not male rats
Strakovsky, R. S., Lezmi, S., Flaws, J. A., Schantz, S. L., Pan, Y. X. & Helferich, W. G., Mar 2014, In: Toxicological Sciences. 138, 1, p. 161-174 14 p., kft331.Research output: Contribution to journal › Article › peer-review
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The regulation of hepatic Pon1 by a maternal high-fat diet is gender specific and may occur through promoter histone modifications in neonatal rats
Strakovsky, R. S., Zhang, X., Zhou, D. & Pan, Y. X., Feb 2014, In: Journal of Nutritional Biochemistry. 25, 2, p. 170-176 7 p.Research output: Contribution to journal › Article › peer-review
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2012
A decrease in DKK1, a WNT inhibitor, contributes to placental lipid accumulation in an obesity-prone rat model
Strakovsky, R. S. & Pan, Y. X., Mar 1 2012, In: Biology of reproduction. 86, 3, 81, 1-11.Research output: Contribution to journal › Article › peer-review
Open Access -
A gestational low-protein diet represses p21WAF1/Cip1 expression in the mammary gland of offspring rats through promoter histone modifications
Zheng, S., Rollet, M., Yang, K. & Pan, Y. X., Sep 28 2012, In: British Journal of Nutrition. 108, 6, p. 998-1007 10 p.Research output: Contribution to journal › Article › peer-review
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Hepatic cellular senescence pathway genes are induced through histone modifications in a diet-induced obese rat model
Zhang, X., Zhou, D., Strakovsky, R., Zhang, Y. & Pan, Y. X., Mar 2012, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 5, p. G558-G564Research output: Contribution to journal › Article › peer-review
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Histone deacetylase 3 (HDAC3) participates in the transcriptional repression of the p16INK4a gene in mammary gland of the female rat offspring exposed to an early-life high-fat diet
Zheng, S., Li, Q., Zhang, Y., Balluf, Z. & Pan, Y. X., Feb 2012, In: Epigenetics. 7, 2, p. 183-190 8 p.Research output: Contribution to journal › Article › peer-review
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In utero oxidative stress epigenetically programs antioxidant defense capacity and adulthood diseases
Strakovsky, R. S. & Pan, Y. X., Jul 15 2012, In: Antioxidants and Redox Signaling. 17, 2, p. 237-253 17 p.Research output: Contribution to journal › Review article › peer-review
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Protein restriction during gestation alters histone modifications at the glucose transporter 4 (GLUT4) promoter region and induces GLUT4 expression in skeletal muscle of female rat offspring
Zheng, S., Rollet, M. & Pan, Y. X., Sep 2012, In: Journal of Nutritional Biochemistry. 23, 9, p. 1064-1071 8 p.Research output: Contribution to journal › Article › peer-review