B.S., Tsinghua University, Beijing, China
M.S., Tsinghua University, Beijing, China
Ph.D., University of California Santa Cruz
Postdoc., University of California Santa Cruz
Postdoc., University of California Los Angeles

Exploring Astrocyte Contributions to Neural Circuits, Behaviors and Diseases

Our emotions and thoughts are generated and processed by a network of different cell types in the brain, including both neurons and glial cells. As the most abundant glial cells, the "star cells" - astrocytes - were discovered more than a century ago but were only considered to have passive supporting functions to neurons. However, many recent studies have challenged this view and suggested that astrocytes are an integral part of the central nervous system.

There are two major questions that we are interested in:

1. What are the cellular and molecular mechanisms by which astrocytes contribute to neural circuit plasticity, motor learning and memory, and the development of neuropsychiatric disorders?
   
   
2. How can we link and predict circuit and behavioral alterations based on astrocyte signaling changes?

To tackle these questions, we will take a systematic approach with innovative genetic tools, in vivo imaging, electrophysiological recordings, next generation sequencing and computational modeling. We hope that our findings will expand the understanding of astrocyte physiology as well as offer mechanistic insights into new biomarkers for early diagnosis and potential therapeutic treatments for neuropsychiatric disorders.

2019 NIH BRAIN Initiative Principal Investigators Meeting Travel Award, National Institutes of Health
2018 – 2019 Brain Research Institute Postdoctoral Award, University of California Los Angeles
2016 – 2017 American Heart Association Postdoctoral Fellowship, American Heart Association

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