William M Brieher

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Research Output

  • 30 Article
  • 2 Conference contribution
  • 2 Review article
  • 1 Chapter
2020
Open Access

Mechanism of Long-Range Chromosome Motion Triggered by Gene Activation

Wang, A., Kolhe, J. A., Gioacchini, N., Baade, I., Brieher, W. M., Peterson, C. L. & Freeman, B. C., Feb 10 2020, In : Developmental cell. 52, 3, p. 309-320.e5

Research output: Contribution to journalArticle

2018

The actin filament bundling protein α-actinin-4 actually suppresses actin stress fibers by permitting actin turnover

Kemp, J. P. & Brieher, W. M., Sep 14 2018, In : Journal of Biological Chemistry. 293, 37, p. 14520-14533 14 p.

Research output: Contribution to journalArticle

2017

CRMP-1 enhances EVL-mediated actin elongation to build lamellipodia and the actin cortex

Yu-Kemp, H. C., Kemp, J. P. & Brieher, W. M., Jan 1 2017, In : Journal of Cell Biology. 216, 8, p. 2463-2479 17 p.

Research output: Contribution to journalArticle

2016

Collapsin response mediator protein-1 regulates Arp2/3-dependent actin assembly

Yu-Kemp, H. C. & Brieher, W. M., Jan 8 2016, In : Journal of Biological Chemistry. 291, 2, p. 658-664 7 p.

Research output: Contribution to journalArticle

Regulation and integrated functions of the actin cytoskeleton

Charras, G. & Brieher, W. M., Mar 15 2016, In : Molecular biology of the cell. 27, 6, 1 p.

Research output: Contribution to journalArticle

2014

Aip1 destabilizes cofilin-saturated actin filaments by severing and accelerating monomer dissociation from ends

Nadkarni, A. V. & Brieher, W. M., Dec 1 2014, In : Current Biology. 24, 23, p. 2749-2757 9 p.

Research output: Contribution to journalArticle

2013

Cadherin junctions and their cytoskeleton(s)

Brieher, W. M. & Yap, A. S., Feb 2013, In : Current Opinion in Cell Biology. 25, 1, p. 39-46 8 p.

Research output: Contribution to journalReview article

Mechanisms of actin disassembly

Brieher, W., Aug 1 2013, In : Molecular biology of the cell. 24, 15, p. 2299-2302 4 p.

Research output: Contribution to journalReview article

2012

The natural product cucurbitacin e inhibits depolymerization of actin filaments

Sörensen, P. M., Iacob, R. E., Fritzsche, M., Engen, J. R., Brieher, W. M., Charras, G. & Eggert, U. S., Sep 21 2012, In : ACS chemical biology. 7, 9, p. 1502-1508 7 p.

Research output: Contribution to journalArticle

α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction

Tang, V. W. & Brieher, W. M., Jan 2012, In : Journal of Cell Biology. 196, 1, p. 115-130 16 p.

Research output: Contribution to journalArticle

2011

Facioscapulohumeral muscular dystrophy region gene 1 Is a dynamic RNA-associated and actin-bundling protein

Sun, C. Y. J., Van Koningsbruggen, S., Long, S. W., Straasheijm, K., Klooster, R., Jones, T. I., Bellini, M., Levesque, L., Brieher, W. M., Van Der Maarel, S. M. & Jones, P. L., Aug 12 2011, In : Journal of Molecular Biology. 411, 2, p. 397-416 20 p.

Research output: Contribution to journalArticle

2010

Facioscapulohumeral muscular dystrophy region gene-1 (FRG-1) is an actin-bundling protein associated with muscle-attachment sites

Liu, Q., Jones, T. I., Tang, V. W., Brieher, W. M. & Jones, P. L., Apr 1 2010, In : Journal of cell science. 123, 7, p. 1116-1123 8 p.

Research output: Contribution to journalArticle

Quantitative analysis of actin turnover in listeria comet tails: Evidence for catastrophic filament turnover

Kueh, H. Y., Brieher, W. M. & Mitchison, T. J., Oct 6 2010, In : Biophysical journal. 99, 7, p. 2153-2162 10 p.

Research output: Contribution to journalArticle

2008

Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers

Hao, Y. K., Charras, G. T., Mitchison, T. J. & Brieher, W. M., Jul 28 2008, In : Journal of Cell Biology. 182, 2, p. 341-353 13 p.

Research output: Contribution to journalArticle

A quantitative analysis of contractility in active cytoskeletal protein networks

Bendix, P. M., Koenderink, G. H., Cuvelier, D., Dogic, Z., Koeleman, B. N., Brieher, W. M., Field, C. M., Mahadevan, L. & Weitz, D. A., Apr 15 2008, In : Biophysical journal. 94, 8, p. 3126-3136 11 p.

Research output: Contribution to journalArticle

Coronin-1A Stabilizes F-Actin by Bridging Adjacent Actin Protomers and Stapling Opposite Strands of the Actin Filament

Galkin, V. E., Orlova, A., Brieher, W., Kueh, H. Y., Mitchison, T. J. & Egelman, E. H., Feb 22 2008, In : Journal of Molecular Biology. 376, 3, p. 607-613 7 p.

Research output: Contribution to journalArticle

Dynamic stabilization of actin filaments

Hao, Y. K., Brieher, W. M. & Mitchison, T. J., Oct 28 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16531-16536 6 p.

Research output: Contribution to journalArticle

Open Access
2007

A Type III Secretion System in Vibrio cholerae Translocates a Formin/Spire Hybrid-like Actin Nucleator to Promote Intestinal Colonization

Tam, V. C., Serruto, D., Dziejman, M., Brieher, W. & Mekalanos, J. J., Apr 19 2007, In : Cell Host and Microbe. 1, 2, p. 95-107 13 p.

Research output: Contribution to journalArticle

Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization

Li, J., Brieher, W. M., Scimone, M. L., Kang, S. J., Zhu, H., Yin, H., von Andrian, U. H., Mitchison, T. & Yuan, J., Mar 1 2007, In : Nature Cell Biology. 9, 3, p. 276-286 11 p.

Research output: Contribution to journalArticle

Cell-free extract systems and the cytoskeleton: Preparation of biochemical experiments for transmission electron microscopy

Coughlin, M., Brieher, W. M. & Ohi, R., Feb 27 2007, Electron Microscopy: Methods and Protocols. Kuo, J. (ed.). p. 199-212 14 p. (Methods in Molecular Biology; vol. 369).

Research output: Chapter in Book/Report/Conference proceedingChapter

2006

Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1

Brieher, W. M., Hao, Y. K., Ballif, B. A. & Mitchison, T. J., Oct 23 2006, In : Journal of Cell Biology. 175, 2, p. 315-324 10 p.

Research output: Contribution to journalArticle

2004

Fascin-mediated propulsion of Listeria monocytogenes independent of frequent nucleation by the Arp2/3 complex

Brieher, W. M., Coughlin, M. & Mitchison, T. J., Apr 26 2004, In : Journal of Cell Biology. 165, 2, p. 233-242 10 p.

Research output: Contribution to journalArticle

1999

Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody

Zhong, Y., Brieher, W. M. & Gumbiner, B. M., Jan 25 1999, In : Journal of Cell Biology. 144, 2, p. 351-359 9 p.

Research output: Contribution to journalArticle

Direct measurements of adhesive interactions between cadherin extracellular domains

Leckband, D., Sivasankar, S., Brieher, W., Lavrik, N. & Gumbiner, B., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains

Sivasankar, S., Brieher, W., Lavrik, N., Gumbiner, B. & Leckband, D., Oct 12 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 21, p. 11820-11824 5 p.

Research output: Contribution to journalArticle

Unusual mechanism controls the adhesive failure of bonds between cadherin extracellular domains

Leckband, D. E., Sivasankar, S., Brieher, W. M., Lavrik, N. & Gumbiner, B., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1997

Lateral clustering of the adhesive ectodomain: A fundamental determinant of cadherin function

Yap, A. S., Brieher, W. M., Pruschy, M. & Gumbiner, B. M., May 1 1997, In : Current Biology. 7, 5, p. 308-315 8 p.

Research output: Contribution to journalArticle

Molecular and functional analysis of cadherin-based adherens junctions

Yap, A. S., Brieher, W. M. & Gumbiner, B. M., Dec 1 1997, In : Annual review of cell and developmental biology. 13, p. 119-146 28 p.

Research output: Contribution to journalArticle

1996

Lateral dimerization is required for the homophilic binding activity of C-cadherin

Brieher, W. M., Yap, A. S. & Gumbiner, B. M., Oct 1996, In : Journal of Cell Biology. 135, 2, p. 487-496 10 p.

Research output: Contribution to journalArticle

1994

Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps

Brieher, W. M. & Gumbiner, B. M., Jul 1 1994, In : Journal of Cell Biology. 126, 2, p. 519-527 9 p.

Research output: Contribution to journalArticle

1993

Induction of a secondary body axis in Xenopus by antibodies to β-catenin

McCrea, P. D., Brieher, W. M. & Gumbiner, B. M., Oct 1993, In : Journal of Cell Biology. 123, 2, p. 477-484 8 p.

Research output: Contribution to journalArticle