1979 …2019
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Research Output 1979 2019

2019

Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERαY537S and ERαD538G mutations

Yu, L., Wang, L., Mao, C., Duraki, D., Kim, J. E., Huang, R., Helferich, W. G., Nelson, E. R., Park, B. H. & Shapiro, D. J., Feb 1 2019, In : Cancer Letters. 442, p. 373-382 10 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Breast Neoplasms
Mutation
Neoplasm Metastasis

Thermally abused frying oil potentiates metastasis to lung in a murine model of late-stage breast cancer

Cam, A., Oyirifi, A. B., Liu, Y., Haschek, W. M., Iwaniec, U. T., Turner, R. T., Engeseth, N. J. & Helferich, W. G., Apr 1 2019, In : Cancer Prevention Research. 12, 4, p. 201-210 10 p.

Research output: Contribution to journalArticle

Oils
Breast Neoplasms
Neoplasm Metastasis
Lipids
Lung
2018

A chiral pool approach for asymmetric syntheses of both antipodes of equol and sativan

Yalamanchili, C., Chittiboyina, A. G., Chandra Kumar Rotte, S., Katzenellenbogen, J. A., Helferich, W. G. & Khan, I. A., Apr 19 2018, In : Tetrahedron. 74, 16, p. 2020-2029 10 p.

Research output: Contribution to journalArticle

Equol
Pharmacology
Isoflavones
Boron
Enantiomers

Albumin as a "trojan Horse" for polymeric nanoconjugate transendothelial transport across tumor vasculatures for improved cancer targeting

Yin, Q., Tang, L., Cai, K., Yang, X., Yin, L., Zhang, Y., Dobrucki, L. W., Helferich, W. G., Fan, T. M. & Cheng, J., May 2018, In : Biomaterials Science. 6, 5, p. 1189-1200 12 p.

Research output: Contribution to journalArticle

Nanoconjugates
Tumors
Albumins
Bearings (structural)
Medical nanotechnology

Iron Fortification of Spiced Vinegar in the Philippines

Lopez Barrera, E. C., Gaur, S., Andrade, J. E., Engeseth, N. J., Nielsen, C. & Helferich, W. G., Oct 2018, In : Journal of food science. 83, 10, p. 2602-2611 10 p.

Research output: Contribution to journalArticle

Philippines
vinegars
Acetic Acid
Iron
iron

Licorice root components mimic estrogens in an object location task but not an object recognition task

Kundu, P., Korol, D. L., Bandara, S., Monaikul, S., Ondera, C. E., Helferich, W. G., Khan, I. A., Doerge, D. R. & Schantz, S. L., Jul 2018, In : Hormones and Behavior. 103, p. 97-106 10 p.

Research output: Contribution to journalArticle

Glycyrrhiza
Estrogens
Powders
Estradiol
Young Adult

The effects of dietary levels of genistein on ovarian follicle number and gene expression

Kundu, P., Patel, S., Meling, D. D., Deal, K., Gao, L., Helferich, W. G. & Flaws, J. A., Oct 2018, In : Reproductive Toxicology. 81, p. 132-139 8 p.

Research output: Contribution to journalArticle

Ovarian Follicle
Genistein
Gene expression
Gene Expression
Ovary

The effects of the botanical estrogen, isoliquiritigenin on delayed spatial alternation

Kundu, P., Neese, S. L., Bandara, S., Monaikul, S., Helferich, W. G., Doerge, D. R., Khan, I. A. & Schantz, S. L., Mar 2018, In : Neurotoxicology and Teratology. 66, p. 55-62 8 p.

Research output: Contribution to journalArticle

Estrogens
Short-Term Memory
Rats
Brain
Dietary supplements
2017

Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model

Wang, H., Wu, X., Lezmi, S., Li, Q., Helferich, W. G., Xu, Y. & Chen, H., Dec 2 2017, In : BMC Complementary and Alternative Medicine. 17, 1, 516.

Research output: Contribution to journalArticle

Ginkgo biloba
Heterografts
Colonic Neoplasms
Neoplasm Metastasis
Liver

Lifetime genistein intake increases the response of mammary tumors to tamoxifen in rats

Zhang, X., Cook, K. L., Warri, A., Cruz, I. M., Rosim, M., Riskin, J., Helferich, W., Doerge, D., Clarke, R. & Hilakivi-Clarke, L., Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 814-824 11 p.

Research output: Contribution to journalArticle

Genistein
Tamoxifen
Breast Neoplasms
Diet
Unfolded Protein Response

Low calcium diet increases 4T1 mammary tumor carcinoma cell burden and bone pathology in mice

Wang, W., Gordon, J. L., Philbrick, K. A., Yang, X., Branscum, A. J., Löhr, C. V., Haschek, W. M., Turner, R. T., Iwaniec, U. T. & Helferich, W. G., Jul 2017, In : PloS one. 12, 7, e0180886.

Research output: Contribution to journalArticle

mammary neoplasms (animal)
Pathology
Nutrition
carcinoma
Tumors

Preconception exposure to dietary levels of genistein affects female reproductive outcomes

Patel, S., Hartman, J. A., Helferich, W. G. & Flaws, J. A., Dec 2017, In : Reproductive Toxicology. 74, p. 174-180 7 p.

Research output: Contribution to journalArticle

Genistein
Litter Size
Birth Rate
Fertility
Estradiol
2016

Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland

Madak-Erdogan, Z., Gong, P., Zhao, Y. C., Xu, L., Wrobel, K. U., Hartman, J. A., Wang, M., Cam, A., Iwaniec, U. T., Turner, R. T., Twaddle, N. C., Doerge, D. R., Khan, I. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Helferich, W. G., Feb 1 2016, In : Molecular Nutrition and Food Research. 60, 2, p. 369-380 12 p.

Research output: Contribution to journalArticle

Glycyrrhiza
licorice
fatty liver
Human Mammary Glands
mammary glands

Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis

Mahalingam, S., Gao, L., Eisner, J., Helferich, W. & Flaws, J. A., Dec 1 2016, In : Reproductive Toxicology. 66, p. 107-114 8 p.

Research output: Contribution to journalArticle

Ovarian Follicle
Growth
Dimethyl Sulfoxide
Estradiol
Estrogens

Effects of letrozole on breast cancer micro-metastatic tumor growth in bone and lung in mice inoculated with murine 4T1 cells

Wang, W., Belosay, A., Yang, X., Hartman, J. A., Song, H., Iwaniec, U. T., Turner, R. T., Churchwell, M. I., Doerge, D. R. & Helferich, W. G., Jun 1 2016, In : Clinical and Experimental Metastasis. 33, 5, p. 475-485 11 p.

Research output: Contribution to journalArticle

letrozole
Bone Development
Breast Neoplasms
Lung
Neoplasms

Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles in vitro

Mahalingam, S., Gao, L., Gonnering, M., Helferich, W. & Flaws, J. A., Mar 15 2016, In : Toxicology and Applied Pharmacology. 295, p. 47-55 9 p.

Research output: Contribution to journalArticle

Equol
Growth
Isoflavones
Ovarian Follicle
Metabolites

Genistein exposure inhibits growth and alters steroidogenesis in adult mouse antral follicles

Patel, S., Peretz, J., Pan, Y. X., Helferich, W. G. & Flaws, J. A., Feb 15 2016, In : Toxicology and Applied Pharmacology. 293, p. 53-62 10 p.

Research output: Contribution to journalArticle

Genistein
Growth
Phytoestrogens
Cell Cycle
Cells

Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action

Zheng, X., Andruska, N., Yu, L., Mao, C., Kim, J. E., Livezey, M., Helferich, W. G. & Shapiro, D. J., Jan 1 2016, In : Steroids. 114, p. 2-6 5 p.

Research output: Contribution to journalReview article

Steroid hormones
Unfolded Protein Response
Cytoplasmic and Nuclear Receptors
Chemical activation
Steroids

Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities

Boonmuen, N., Gong, P., Ali, Z., Chittiboyina, A. G., Khan, I., Doerge, D. R., Helferich, W. G., Carlson, K. E., Martin, T., Piyachaturawat, P., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Jan 1 2016, In : Steroids. 105, p. 42-49 8 p.

Research output: Contribution to journalArticle

Dietary supplements
Glycyrrhiza
Selective Estrogen Receptor Modulators
Dietary Supplements
Estrogen Receptors

Long-lasting impairments in adult neurogenesis, spatial learning and memory from a standard chemotherapy regimen used to treat breast cancer

Rendeiro, C., Sheriff, A., Bhattacharya, T. K., Gogola, J. V., Baxter, J. H., Chen, H., Helferich, W. G., Roy, E. J. & Rhodes, J. S., Dec 15 2016, In : Behavioural Brain Research. 315, p. 10-22 13 p.

Research output: Contribution to journalArticle

Neurogenesis
Breast Neoplasms
Drug Therapy
Bromodeoxyuridine
Cognition

Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis

Yin, Q., Tang, L., Cai, K., Tong, R., Sternberg, R., Yang, X., Dobrucki, L. W., Borst, L. B., Kamstock, D., Song, Z., Helferich, W. G., Cheng, J. & Fan, T. M., Aug 9 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 32, p. E4601-E4609

Research output: Contribution to journalArticle

pamidronate
Nanoconjugates
Osteolysis
Nanoparticles
Doxorubicin

Pharmacokinetics of isoflavones from soy infant formula in neonatal and adult rhesus monkeys

Doerge, D. R., Woodling, K. A., Churchwell, M. I., Fleck, S. C. & Helferich, W. G., Jun 1 2016, In : Food and Chemical Toxicology. 92, p. 165-176 12 p.

Research output: Contribution to journalArticle

Infant Formula
Isoflavones
Pharmacokinetics
infant formulas
isoflavones

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In : Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

Research output: Contribution to journalArticle

Dioscorea
Saponins
Cells
Breast Neoplasms
Cell Line
2015

A multi-targeted approach to suppress tumor-promoting inflammation

Samadi, A. K., Bilsland, A., Georgakilas, A. G., Amedei, A., Amin, A., Bishayee, A., Azmi, A. S., Lokeshwar, B. L., Grue, B., Panis, C., Boosani, C. S., Poudyal, D., Stafforini, D. M., Bhakta, D., Niccolai, E., Guha, G., Vasantha Rupasinghe, H. P., Fujii, H., Honoki, K., Mehta, K. & 15 others, Aquilano, K., Lowe, L., Hofseth, L. J., Ricciardiello, L., Ciriolo, M. R., Singh, N., Whelan, R. L., Chaturvedi, R., Ashraf, S. S., Shantha Kumara, H. M. C., Nowsheen, S., Mohammed, S. I., Keith, W. N., Helferich, W. G. & Yang, X., Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S151-S184

Research output: Contribution to journalReview article

Inflammation
Neoplasms
Anti-Inflammatory Agents
Macrophage Migration-Inhibitory Factors
CXC Chemokines

Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer

Andruska, N., Zheng, X., Yang, X., Helferich, W. G. & Shapiro, D. J., Jul 21 2015, In : Oncogene. 34, 29, p. 3760-3769 10 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Estrogen Receptors
Estrogens
Cell Proliferation
Breast Neoplasms

Broad targeting of resistance to apoptosis in cancer

Mohammad, R. M., Muqbil, I., Lowe, L., Yedjou, C., Hsu, H. Y., Lin, L. T., Siegelin, M. D., Fimognari, C., Kumar, N. B., Dou, Q. P., Yang, H., Samadi, A. K., Russo, G. L., Spagnuolo, C., Ray, S. K., Chakrabarti, M., Morre, J. D., Coley, H. M., Honoki, K., Fujii, H. & 19 others, Georgakilas, A. G., Amedei, A., Niccolai, E., Amin, A., Ashraf, S. S., Helferich, W. G., Yang, X., Boosani, C. S., Guha, G., Bhakta, D., Ciriolo, M. R., Aquilano, K., Chen, S., Mohammed, S. I., Keith, W. N., Bilsland, A., Halicka, D., Nowsheen, S. & Azmi, A. S., Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S78-S103

Research output: Contribution to journalReview article

Apoptosis
Neoplasms
Cell Death
Gossypol
Cell Nucleus Active Transport

Cancer prevention and therapy through the modulation of the tumor microenvironment

Casey, S. C., Amedei, A., Aquilano, K., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A. E., Boosani, C. S., Chen, S., Ciriolo, M. R., Crawford, S., Fujii, H., Georgakilas, A. G., Guha, G., Halicka, D., Helferich, W. G., Heneberg, P., Honoki, K., Keith, W. N., Kerkar, S. P. & 11 others, Mohammed, S. I., Niccolai, E., Nowsheen, S., Vasantha Rupasinghe, H. P., Samadi, A., Singh, N., Talib, W. H., Venkateswaran, V., Whelan, R. L., Yang, X. & Felsher, D. W., Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S199-S223

Research output: Contribution to journalReview article

Tumor Microenvironment
piperine
Neoplasms
Carcinogenesis
Indoleamine-Pyrrole 2,3,-Dioxygenase

Designing a broad-spectrum integrative approach for cancer prevention and treatment

Block, K. I., Gyllenhaal, C., Lowe, L., Amedei, A., Ruhul Amin, A. R. M., Amin, A., Aquilano, K., Arbiser, J., Arreola, A., Arzumanyan, A., Salman Ashraf, S., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A., Bishayee, A., Blain, S. W., Block, P. B., Boosani, C. S., Carey, T. E. & 160 others, Carnero, A., Carotenuto, M., Casey, S. C., Chakrabarti, M., Chaturvedi, R., Chen, G. Z., Chen, H., Chen, S., Chen, Y. C., Choi, B. K., Ciriolo, M. R., Coley, H. M., Collins, A. R., Connell, M., Crawford, S., Curran, C. S., Dabrosin, C., Damia, G., Dasgupta, S., DeBerardinis, R. J., Decker, W. K., Dhawan, P., Diehl, A. M. E., Dong, J. T., Dou, Q. P., Drewa, J. E., Elkord, E., El-Rayes, B., Feitelson, M. A., Felsheru, D. W., Ferguson, L. R., Fimognari, C., Firestone, G. L., Frezza, C., Fujii, H., Fuster, M. M., Generali, D., Georgakilas, A. G., Gieseler, F., Gilbertson, M., Green, M. F., Grue, B., Guhal, G., Halicka, D., Helferich, W. G., Heneberg, P., Hentosh, P., Hirschey, M. D., Hofseth, L. J., Holcombe, R. F., Honoki, K., Hsu, H. Y., Huang, G. S., Jensen, L. D., Jiang, W. G., Jones, L. W., Karpowicz, P. A., Keith, W. N., Kerkar, S. P., Khan, G. N., Khatami, M., Ko, Y. H., Kucuk, O., Kulathinal, R. J., Kumar, N. B., Kwon, B. S., Leb, A., Leab, M. A., Lee, H. Y., Lichtor, T., Lin, L. T., Locasale, J. W., Lokeshwar, B. L., Longo, V. D., Lyssiotis, C. A., MacKenzie, K. L., Malhotra, M., Marino, M., Martinez-Chantar, M. L., Matheu, A., Maxwellx, C., McDonnell, E., Meeker, A. K., Mehrmohamadi, M., Mehta, K., Michelotti, G. A., Mohammad, R. M., Mohammed, S. I., Morre, D. J., Muqbil, I., Muralidharcq, V., Murphy, M. P., Nagaraju, G. P., Nahta, R., Niccolai, E., Nowsheen, S., Panis, C., Pantano, F., Parslow, V. R., Pawelec, G., Pedersen, P. L., Poore, B., Poudyal, D., Prakash, S., Prince, M., Raffaghello, L., Rathmell, J. C., Rathmell, W. K., Ray, S. K., Reichrath, J., Rezazadeh, S., Ribatti, D., Ricciardiello, L., Robeydf, R. B., Rodierdh, F., Rupasinghe, H. P. V., Russo, G. L., Ryan, E. P., Samadi, A. K., Sanchez-Garcia, I., Sanders, A. J., Santini, D., Sarkar, M., Sasada, T., Saxena, N. K., Shackelford, R. E., Shantha Kumara, H. M. C., Sharma, D., Shin, D. M., Sidransky, D., Siegelin, M. D., Signori, E., Singh, N., Sivanand, S., Sliva, D., Smythe, C., Spagnuolo, C., Stafforini, D. M., Stagg, J., Subbarayan, P. R., Sundin, T., Talib, W. H., Thompson, S. K., Tran, P. T., Ungefroren, H., Vander Heiden, M. G., Venkateswaran, V., Vinay, D. S., Vlachostergios, P. J., Wang, Z., Wellen, K. E., Whelan, R. L., Yang, E. S., Yang, H., Yang, X., Yaswen, P., Yedjou, C., Yin, X., Zhu, J. & Zollo, M., Jan 1 2015, In : Seminars in Cancer Biology. 35, p. S276-S304

Research output: Contribution to journalReview article

Tumor Microenvironment
Recurrence
Neoplasms
Genetic Heterogeneity
Poisons
High Fat Diet
Nutrition
Gene expression
Fats
Parturition

Development of a point-of-use fortification technology for delivery of micronutrients in Honduras

Andrade, J., Rosales, E., Lopez, J. R., Carrillo, E. P., Engeseth, N. J. & Helferich, W. G., Jan 30 2015, In : Journal of the Science of Food and Agriculture. 95, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Honduras
Micronutrients
dietary minerals
Technology
rice

Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors

Yang, X., Belosay, A., Hartman, J. A., Song, H., Zhang, Y., Wang, W., Doerge, D. R. & Helferich, W. G., Apr 8 2015, In : Clinical and Experimental Metastasis. 32, 4, p. 323-333 11 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Isoflavones
Theoretical Models
Breast Neoplasms
Neoplasm Metastasis

Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression

Andruska, N. D., Zheng, X., Yang, X., Mao, C., Cherian, M. M., Mahapatra, L., Helferich, W. G. & Shapiro, D. J., Apr 14 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 15, p. 4737-4742 6 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Estrogen Receptors
Endoplasmic Reticulum
Neoplasms
Peptide Elongation Factor 2

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

Ferguson, L. R., Chen, H., Collins, A. R., Connell, M., Damia, G., Dasgupta, S., Malhotra, M., Meeker, A. K., Amedei, A., Amin, A., Ashraf, S. S., Aquilano, K., Azmi, A. S., Bhakta, D., Bilsland, A., Boosani, C. S., Chen, S., Ciriolo, M. R., Fujii, H., Guha, G. & 15 others, Halicka, D., Helferich, W. G., Keith, W. N., Mohammed, S. I., Niccolai, E., Yang, X., Honoki, K., Parslow, V. R., Prakash, S., Rezazadeh, S., Shackelford, R. E., Sidransky, D., Tran, P. T., Yang, E. S. & Maxwell, C. A., Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S5-S24

Research output: Contribution to journalReview article

Genomic Instability
Diet
Neoplasms
DNA Damage
Centrosome

Immune evasion in cancer: Mechanistic basis and therapeutic strategies

Vinay, D. S., Ryan, E. P., Pawelec, G., Talib, W. H., Stagg, J., Elkord, E., Lichtor, T., Decker, W. K., Whelan, R. L., Kumara, H. M. C. S., Signori, E., Honoki, K., Georgakilas, A. G., Amin, A., Helferich, W. G., Boosani, C. S., Guha, G., Ciriolo, M. R., Chen, S., Mohammed, S. I. & 12 others, Azmi, A. S., Keith, W. N., Bilsland, A., Bhakta, D., Halicka, D., Fujii, H., Aquilano, K., Ashraf, S. S., Nowsheen, S., Yang, X., Choi, B. K. & Kwon, B. S., Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S185-S198

Research output: Contribution to journalReview article

Immune Evasion
Neoplasms
Therapeutics
Phytochemicals
Tumor Escape
Adipogenesis
Glucose Intolerance
Dietary Fats
Rats
Glucose

Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice

Liu, Y., Hilakivi-Clarke, L., Zhang, Y., Wang, X., Pan, Y. X., Xuan, J., Fleck, S. C., Doerge, D. R. & Helferich, W. G., Aug 1 2015, In : Molecular Nutrition and Food Research. 59, 8, p. 1419-1430 12 p.

Research output: Contribution to journalArticle

Isoflavones
soy flour
Flour
isoflavones
Nude Mice

Long-term exposure to dietary sources of genistein induces estrogen-independence in the human breast cancer (MCF-7) xenograft model

Andrade, J. E., Ju, Y. H., Baker, C., Doerge, D. R. & Helferich, W. G., Mar 1 2015, In : Molecular Nutrition and Food Research. 59, 3, p. 413-423 11 p.

Research output: Contribution to journalArticle

Genistein
genistein
chronic exposure
Heterografts
breast neoplasms

Redox-responsive self-assembled chain-shattering polymeric therapeutics

Cai, K., Yen, J., Yin, Q., Liu, Y., Song, Z., Lezmi, S., Zhang, Y., Yang, X., Helferich, W. G. & Cheng, J., Jul 1 2015, In : Biomaterials Science. 3, 7, p. 1061-1065 5 p.

Research output: Contribution to journalArticle

Polyethylene glycols
Nanoparticles
Polycondensation
Pharmaceutical Preparations
Particle size

Tissue invasion and metastasis: Molecular, biological and clinical perspectives

Jiang, W. G., Sanders, A. J., Katoh, M., Ungefroren, H., Gieseler, F., Prince, M., Thompson, S. K., Zollo, M., Spano, D., Dhawan, P., Sliva, D., Subbarayan, P. R., Sarkar, M., Honoki, K., Fujii, H., Georgakilas, A. G., Amedei, A., Niccolai, E., Amin, A., Ashraf, S. S. & 16 others, Ye, L., Helferich, W. G., Yang, X., Boosani, C. S., Guha, G., Ciriolo, M. R., Aquilano, K., Chen, S., Azmi, A. S., Keith, W. N., Bilsland, A., Bhakta, D., Halicka, D., Nowsheen, S., Pantano, F. & Santini, D., Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S244-S275

Research output: Contribution to journalReview article

Neoplasm Metastasis
Neoplasms
Milk Thistle
Cordyceps
Reishi
2014

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

Aumsuwan, P., Khan, S. I., Khan, I. A., Avula, B., Walker, L. A., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Jan 1 2014, In : In Vitro Cellular and Developmental Biology - Animal. 51, 1, p. 59-71 13 p.

Research output: Contribution to journalArticle

5-methyldeoxycytidine
Dioscorea
Epigenomics
MCF-7 Cells
Breast Neoplasms

Genistein exposure during the early postnatal period favors the development of obesity in female, but not male rats

Strakovsky, R. S., Lezmi, S., Flaws, J. A., Schantz, S. L., Pan, Y-X. & Helferich, W. G., Mar 1 2014, In : Toxicological Sciences. 138, 1, p. 161-174 14 p., kft331.

Research output: Contribution to journalArticle

Genistein
Rats
Obesity
Fats
CCAAT-Enhancer-Binding Protein-alpha

Investigating the optimal size of anticancer nanomedicine

Tang, L., Yang, X., Yin, Q., Cai, K., Wang, H., Chaudhury, I., Yao, C., Zhou, Q., Kwon, M., Hartman, J. A., Dobrucki, I. T., Dobrucki, L. W., Borst, L. B., Lezmi, S., Helferich, W. G., Ferguson, A. L., Fan, T. M. & Cheng, J., Oct 28 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 43, p. 15344-15349 6 p.

Research output: Contribution to journalArticle

Nanomedicine
Neoplasms
Nanoconjugates
United States Food and Drug Administration
Particle Size

The effects of dietary treatment with S-equol on learning and memory processes in middle-aged ovariectomized rats

Neese, S. L., Pisani, S. L., Doerge, D. R., Helferich, W. G., Sepehr, E., Chittiboyina, A. G., Rotte, S. C. K., Smillie, T. J., Khan, I. A., Korol, D. L. & Schantz, S. L., Jan 1 2014, In : Neurotoxicology and Teratology. 41, p. 80-88 9 p.

Research output: Contribution to journalArticle

Equol
Rats
Learning
Genistein
Data storage equipment
Gene Regulatory Networks
Estrogen Receptors
Estrogens
Gene Expression
Glycyrrhiza
2013

Association between Absolute Tumor Burden and Serum Bone-Specific Alkaline Phosphatase in Canine Appendicular Osteosarcoma

Sternberg, R. A., Pondenis, H. C., Yang, X., Mitchell, M. A., O'Brien, R. T., Garrett, L. D., Helferich, W. G., Hoffmann, W. E. & Fan, T. M., Jul 1 2013, In : Journal of veterinary internal medicine. 27, 4, p. 955-963 9 p.

Research output: Contribution to journalArticle

osteosarcoma
Osteosarcoma
Tumor Burden
Alkaline Phosphatase
alkaline phosphatase

Estradiol increases ER-negative breast cancer metastasis in an experimental model

Yang, X., Belosay, A., Du, M., Fan, T. M., Turner, R. T., Iwaniec, U. T. & Helferich, W. G., Aug 1 2013, In : Clinical and Experimental Metastasis. 30, 6, p. 711-721 11 p.

Research output: Contribution to journalArticle

Estradiol
Theoretical Models
Breast Neoplasms
Neoplasm Metastasis
Neoplasms

Genistein administered as a once-daily oral supplement had no beneficial effect on the tibia in rat models for postmenopausal bone loss

Turner, R. T., Iwaniec, U. T., Andrade, J. E., Branscum, A. J., Neese, S. L., Olson, D. A., Wagner, L., Wang, V. C., Schantz, S. L. & Helferich, W. G., Jun 1 2013, In : Menopause. 20, 6, p. 677-686 10 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Genistein
Tibia
Bone and Bones
Dietary Supplements

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

Jiang, Y., Gong, P., Madak-Erdogan, Z., Martin, T. A., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T. J., Chittiboyina, A. G., Rotte, S. C. K., Helferich, W. G., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Nov 1 2013, In : FASEB Journal. 27, 11, p. 4406-4418 13 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Gene expression
Chromatin
Equol

Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo

Xing, H., Tang, L., Yang, X., Hwang, K., Wang, W., Yin, Q., Wong, N. Y., Dobrucki, L. W., Yasui, N., Katzenellenbogen, J. A., Helferich, W. G., Cheng, J. & Lu, Y., Oct 21 2013, In : Journal of Materials Chemistry B. 1, 39, p. 5288-5297 10 p.

Research output: Contribution to journalArticle

Liposomes
Cells
Nucleotide Aptamers
Breast Neoplasms
Nude Mice
2012

Acute genistein treatment mimics the effects of estradiol by enhancing place learning and impairing response learning in young adult female rats

Pisani, S. L., Neese, S. L., Doerge, D. R., Helferich, W. G., Schantz, S. L. & Korol, D. L., Sep 1 2012, In : Hormones and Behavior. 62, 4, p. 491-499 9 p.

Research output: Contribution to journalArticle

Genistein
Young Adult
Estradiol
Learning
Estrogen Receptors