Wilfred Adrianus van der Donk

1990 …2019
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Biosynthesis Chemical Compounds
Bacteriocins Medicine & Life Sciences
Peptides Chemical Compounds
Ligases Medicine & Life Sciences
Substrates Chemical Compounds
Biological Products Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Sulfides Medicine & Life Sciences

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Research Output 1990 2019

Investigations into the Mechanism of Action of Sublancin

Wu, C., Biswas, S., Garcia De Gonzalo, C. V. & van der Donk, W. A., Jan 1 2019, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journalArticle

Glucose
Biological Products
DNA Replication
Cell Wall
Carbon

Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin

Bougioukou, D. J., Ting, C. P., Peck, S. C., Mukherjee, S. & van der Donk, W. A., Jan 1 2019, In : Organic and Biomolecular Chemistry. 17, 4, p. 822-829 8 p.

Research output: Contribution to journalArticle

enzymes
analogs
Enzymes
RNA, Transfer, Leu
peptides
Isotopes
isotope
kinetics
Kinetics
Hydrides

A lanthipeptide library used to identify a protein-protein interaction inhibitor article

Yang, X., Lennard, K. R., He, C., Walker, M. C., Ball, A. T., Doigneaux, C., Tavassoli, A. & van der Donk, W. A., Apr 1 2018, In : Nature chemical biology. 14, 4, p. 375-380 6 p.

Research output: Contribution to journalArticle

Libraries
Proteins
Human Immunodeficiency Virus Proteins
Ligases
Biological Products

Characterization of Leader Peptide Binding during Catalysis by the Nisin Dehydratase NisB

Repka, L. M., Hetrick, K. J., Chee, S. H. & van der Donk, W. A., Mar 28 2018, In : Journal of the American Chemical Society. 140, 12, p. 4200-4203 4 p.

Research output: Contribution to journalArticle

Hydro-Lyases
Nisin
catalysis
Protein Sorting Signals
Catalysis